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Périmètre
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10635 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 5743
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| MT1013 NCT07122401 · Study of MT1013 for the Treatment of Patients With Secondary Hyperparathyroidism | Maladie rénale chronique | À vérifier | Phase 3 | RECRUITING | MT1013 is a first-in-class dual-target agonist. This study is a multicente… À vérifier | ClinicalTrials.gov 2026-11-08 04:38:05 | Détail |
| Acupuncture NCT07888777 · Manual Acupuncture for Intradialytic Nausea and Vomiting in Patients Undergoing… | Maladie rénale chronique | À vérifier | Non applicable | NOT_YET_RECRUITING | The goal of this clinical trial is to determine the effectiveness of Tai C… À vérifier | ClinicalTrials.gov 2026-11-08 04:38:03 | Détail |
| AI-Guided Relaxation Platform NCT07522944 · AI-Guided Personalized Relaxation for Hemodialysis Patients | Maladie rénale chronique | Traitement symptomatique | Non applicable | COMPLETED | Patients undergoing maintenance hemodialysis frequently experience impaire… À vérifier | ClinicalTrials.gov 2026-11-08 04:38:03 | Détail |
| Empagliflozin NCT07348484 · Urinary Biomarker-Based Diagnostic and Monitoring System for Chronic Kidney Dise… | Maladie rénale chronique | À vérifier | À vérifier | RECRUITING | The purpose of this study is to find out what effects (good and bad) the s… À vérifier | ClinicalTrials.gov 2026-11-08 04:38:03 | Détail |
| Finerenone (BAY 94-8862) NCT06278207 · An Observational Study Called FINEROD to Learn More About the Use of the Treatme… | Maladie rénale chronique | À vérifier | À vérifier | RECRUITING | This is an observational study, in which data from people in Asia and in t… À vérifier | ClinicalTrials.gov 2026-11-08 04:38:03 | Détail |
| Finerenone (Kerendia, BAY948862) NCT06763146 · IN-REALITY — An Observational Study to Learn More About How Safe Finerenone is a… | Maladie rénale chronique | Thérapie génique | À vérifier | ACTIVE_NOT_RECRUITING | This is an observational study in which data from people with chronic kidn… À vérifier | ClinicalTrials.gov 2026-11-08 04:38:03 | Détail |
| Human Wharton's jelly mesenchymal stem cell (HWJ-MSC) exosomes NCT07922889 · Mesenchymal Stem Cell Exosomes Alone or Combined With HUVEC Exosomes in Non-Dial… | Maladie rénale chronique | Ralentissement de la progression · Immunomodulation · Thérapie cellulaire · Thé… | Phase 1/2 | COMPLETED | The goal of this clinical trial is to learn whether a single intravenous i… À vérifier | ClinicalTrials.gov 2026-11-08 04:38:03 | Détail |
| Non-Invasive Positive Pressure Ventilation NCT07558265 · WINDSURFER — WIN Ratio Analysis to Determine a Strategy of Non- Invasive SUpport… | Maladie rénale chronique | À vérifier | Non applicable | RECRUITING | The purpose of this clinical trial is to determine the best initial non-in… À vérifier | ClinicalTrials.gov 2026-11-08 04:38:03 | Détail |
| Transcutaneous electrical nerve stimulation unit (TENS) NCT05981183 · Transcutaneous Auricular Vagus Nerve Stimulation Device in CKD Population | Maladie rénale chronique | À vérifier | Non applicable | RECRUITING | The purpose of this pilot interventional study is to collect preliminary d… À vérifier | ClinicalTrials.gov 2026-11-08 04:38:03 | Détail |
| Truway Portable Ultrasound Device NCT07209527 · TruDxPC — Truway Diagnostic Tools in Primary Care | Maladie rénale chronique | À vérifier | Phase 1 | ENROLLING_BY_INVITATION | This study evaluates the effectiveness of Truway Health-sourced portable d… À vérifier | ClinicalTrials.gov 2026-11-08 04:38:03 | Détail |
| Vitamin C NCT07184866 · VITAKI-ACLF — Vitamin C for Acute Kidney Injury in ACLF With Septic Shock: A Ran… | Maladie rénale chronique | Immunomodulation | Non applicable | NOT_YET_RECRUITING | This study is testing whether Vitamin C can help improve kidney function a… À vérifier | ClinicalTrials.gov 2026-11-08 04:38:03 | Détail |
| Atrasentan NCT07498335 · ADVANCE — Study to Assess the Efficacy, Pharmacokinetics, Safety and Tolerabilit… | Maladie rénale chronique | À vérifier | Phase 3 | RECRUITING | A Phase III, single-arm, multicenter pediatric clinical study evaluating a… À vérifier | ClinicalTrials.gov 2026-11-08 04:38:02 | Détail |
| Empagliflozin 10 MG NCT05786443 · SEED — Safety and Efficacy of Empagliflozin in Hemodialysis | Maladie rénale chronique | À vérifier | Phase 2 | ACTIVE_NOT_RECRUITING | A 12-week, phase II, randomized, double-blind, placebo-controlled, multi-c… À vérifier | ClinicalTrials.gov 2026-11-08 04:38:02 | Détail |
| Omnisol organ preservation solution NCT07920926 · OMNIPUMP — Hypothermic Kidney Machine Perfusion With Omnisol | Maladie rénale chronique | À vérifier | Non applicable | NOT_YET_RECRUITING | Insufficient availability of organs from brain dead (DBD) and living donor… À vérifier | ClinicalTrials.gov 2026-11-08 04:38:02 | Détail |
| Adaptive Tip Catheter NCT07367100 · PHAST — A Pivotal Study Evaluating Safety and Effectiveness of Adaptative Tip Ca… | Accident vasculaire cérébral | À vérifier | Non applicable | RECRUITING | The purpose of this study is to assess the safety and the effectiveness of… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:58 | Détail |
| Continuous Theta Burst Stimulation (cTBS) NCT07834333 · Effectiveness of Theta Burst Stimulation For Upper and Lower Extremity Recovery… | Accident vasculaire cérébral | Traitement symptomatique | Non applicable | RECRUITING | This single-center, single-blind, randomized, sham-controlled clinical tri… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:58 | Détail |
| High-dose accelerated intermittent theta burst stimulation (aiTBS) NCT07909954 · Accelerated Theta-Burst Stimulation for Refractory Central Post-Stroke Pain | Accident vasculaire cérébral | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This pilot study aims to evaluate the feasibility, safety, and preliminary… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:58 | Détail |
| HRS-4029 NCT07739160 · The Efficacy and Safety of HRS-4029 in Acute Ischemic Stroke Patients | Accident vasculaire cérébral | À vérifier | Phase 2 | RECRUITING | This trial will evaluate the efficacy and safety of HRS-4029 compared with… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:58 | Détail |
| Non-invasive Electrical Spinal Cord Stimulation NCT05591196 · HARNESS — Hand and Arm Motor Recovery Via Non-invasive Electrical Spinal Cord St… | Accident vasculaire cérébral | Ralentissement de la progression | Non applicable | RECRUITING | The recovery from a stroke is often incomplete. It is the leading cause of… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:58 | Détail |
| Thromboaspiration catheter NCT07571954 · iNFLOW-5 — Efficacy and Safety Evaluation of iNstroke 5F Aspiration Catheter for… | Accident vasculaire cérébral | À vérifier | Non applicable | NOT_YET_RECRUITING | Prospective, single-arm, multi-centre study to evaluate the efficacy and s… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:58 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4871
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Effects of continuous vs. intermittent transcutaneous electrical stim… Transcutaneous electrical nerve stimulation unit (TENS) · PMID 41866984 | Maladie rénale chronique | Traitement symptomatique | Publication | PubMed | Voir la publication source To compare the effects of two transcutaneous electrical stimulation (TES) patterns applied to the auricular branches of… | Cranio : the journal of craniomandibular practice 2026-11-08 04:38:07 | Source |
| Optimizing Percutaneous Tibial Nerve Stimulation Intensity for Overac… Transcutaneous electrical nerve stimulation unit (TENS) · PMID 42554545 | Maladie rénale chronique | Traitement symptomatique | Publication | PubMed | Voir la publication source Overactive bladder (OAB) is a significant global health issue. The standard percutaneous tibial nerve stimulation (PTNS… | Neuromodulation : journal of the International Neuromo… 2026-11-08 04:38:07 | Source |
| Transcutaneous auricular vagus nerve stimulation improves dysautonomi… Transcutaneous electrical nerve stimulation unit (TENS) · PMID 42802247 | Maladie rénale chronique | Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source Autonomic nervous system dysfunction is highly prevalent in hypermobile Ehlers-Danlos syndrome (hEDS) and contributes s… | Neurological sciences : official journal of the Italia… 2026-11-08 04:38:07 | Source |
| Factors associated with high-flow therapy failure in COVID-19-related… Non-Invasive Positive Pressure Ventilation · PMID 42888091 | Maladie rénale chronique | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source The optimal selection of non-invasive respiratory support for patients with COVID-19-related acute hypoxemic respirator… | Enfermedades infecciosas y microbiologia clinica (Engl… 2026-11-08 04:38:06 | Source |
| High-Flow Nasal Cannula in Adult Acute Care: Physiological Mechanisms… Non-Invasive Positive Pressure Ventilation · PMID 42942512 | Maladie rénale chronique | À vérifier | Publication | PubMed | Voir la publication source High-flow nasal cannula (HFNC) oxygen therapy is widely used in emergency, intensive care, perioperative, and procedura… | Medicina (Kaunas, Lithuania) 2026-11-08 04:38:06 | Source |
| Impact of respiratory support on time to achieve full oral feeding in… Non-Invasive Positive Pressure Ventilation · PMID 42871336 | Maladie rénale chronique | À vérifier | Publication | PubMed | Voir la publication source Very low birth weight infants often require respiratory support, which may delay full oral feeding. The independent rol… | Frontiers in pediatrics 2026-11-08 04:38:06 | Source |
| A comparative analysis of 3MAX aspiration versus 3 mm Trevo Retriever… Thromboaspiration catheter · PMID 31243066 | Accident vasculaire cérébral | À vérifier | Publication | PubMed | Voir la publication source Although aspiration and stent retriever thrombectomy perform similarly in proximal occlusions, no comparative series ar… | Journal of neurointerventional surgery 2026-11-08 04:38:02 | Source |
| Percutaneous Pulmonary Thrombectomy Beyond Acute Pulmonary Embolism:… Thromboaspiration catheter · PMID 38385241 | Accident vasculaire cérébral | Thérapie génique | Publication | PubMed | Voir la publication source Subacute massive pulmonary embolism is an uncommon manifestation of severe pulmonary embolism associated with poor prog… | Journal of endovascular therapy : an official journal… 2026-11-08 04:38:02 | Source |
| Simplified classification of cavernous internal carotid artery tortuo… Thromboaspiration catheter · PMID 35475775 | Hypertension artérielle · Accident vasculaire cérébral | Thérapie génique | Publication | PubMed | Voir la publication source Thromboaspiration catheters are increasingly used for the endovascular treatment of large vessel stroke (LVS), while to… | Neurological research 2026-11-08 04:38:02 | Source |
| Multifocal continuous theta burst stimulation in idiopathic generaliz… Continuous Theta Burst Stimulation (cTBS) · PMID 42731195 | Accident vasculaire cérébral | Traitement symptomatique | Publication | PubMed | Voir la publication source Idiopathic generalized epilepsy (IGE) is a disorder of the cortico-subcortical networks. Continuous theta burst stimula… | Clinical neurophysiology : official journal of the Int… 2026-11-08 04:38:00 | Source |
| Optimizing brain functional-structural architecture with cTBS to redu… Continuous Theta Burst Stimulation (cTBS) · PMID 42457860 | Accident vasculaire cérébral | À vérifier | Publication | PubMed | Voir la publication source Alcohol use disorder (AUD) is characterized by high relapse rates, necessitating novel interventions. Continuous theta-… | Molecular psychiatry 2026-11-08 04:38:00 | Source |
| Digital Outreach to Improve Statin Refills in Patients With Low Stati… Cordio System · PMID 42667613 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Statin nonadherence is a leading, addressable driver of preventable cardiovascular events. Although health systems rout… | JAMA 2026-11-08 04:37:54 | Source |
| Endovascular ablation of the right greater splanchnic nerve for the m… Right Greater Splanchnic Nerve (GSN) ablation · PMID 42257781 | Insuffisance cardiaque | Traitement symptomatique | Publication | PubMed | Voir la publication source Heart failure with preserved ejection fraction (HFpEF) remains difficult to manage because conventional therapies often… | The Egyptian heart journal : (EHJ) : official bulletin… 2026-11-08 04:37:54 | Source |
| Incidence, medical therapy, and outcomes in heart failure with improv… Cordio System · PMID 42702264 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source To assess the incidence of heart failure with improved ejection fraction (HFimpEF) across guideline definitions (ACC/AH… | American heart journal 2026-11-08 04:37:54 | Source |
| Relationship Between the Azygos Vein and the Greater Splanchnic Nerve… Right Greater Splanchnic Nerve (GSN) ablation · PMID 42249803 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Although ablation of the greater splanchnic nerve is now being used to treat some patients with heart failure, the anat… | Clinical anatomy (New York, N.Y.) 2026-11-08 04:37:54 | Source |
| Validation of the PREVENT-HF Risk Prediction Equation in US Veterans. Cordio System · PMID 42969140 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Résumé non disponible dans la base locale. | Circulation 2026-11-08 04:37:54 | Source |
| Changes in right ventricular-pulmonary artery coupling after transcat… Tricuspid Transcatheter Edge-to-Edge Repair (TEER) · PMID 42822601 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Right ventricular-pulmonary artery (RV-PA) coupling is an established marker of prognosis in mitral regurgitation (MR),… | International journal of cardiology 2026-11-08 04:37:47 | Source |
| Intraprocedural evaluation of residual mitral and tricuspid regurgita… Tricuspid Transcatheter Edge-to-Edge Repair (TEER) · PMID 42982241 | Maladie coronarienne | À vérifier | Publication | PubMed | Voir la publication source Transcatheter edge-to-edge repair (TEER) has emerged as an established therapeutic option for selected patients with se… | International journal of cardiology 2026-11-08 04:37:47 | Source |
| Tricuspid transcatheter edge-to-edge repair versus transcatheter tric… Tricuspid Transcatheter Edge-to-Edge Repair (TEER) · PMID 42989943 | Maladie coronarienne | À vérifier | Publication | PubMed | Voir la publication source Recent clinical studies of tricuspid transcatheter edge-to-edge repair (T-TEER) and transcatheter tricuspid valve repla… | Current opinion in cardiology 2026-11-08 04:37:47 | Source |
| Automated Production of Gene-Edited CAR-T Cells for People Living wit… RAPA-501 Autologous T stem cells · PMID 42847201 | Cancer | Thérapie cellulaire · Thérapie génique | Publication | PubMed | Voir la publication source Adoptive transfer of gene-modified autologous T cells, for example, expressing chimeric antigen receptors (CARs), is a… | Human gene therapy 2026-11-08 04:37:39 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||