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8666 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 4050
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Lm-LLO-TT NCT07828236 · PHASE 1 TRIAL OF Lm-LLO-TT AND GEMCITABINE IN UNRESECTABLE PANCREATIC DUCTAL ADE… | Cancer | Traitement symptomatique | Phase 1 | NOT_YET_RECRUITING | ClinicalTrials.gov Brief Summary This Phase 1, open-label, first-in-human… À vérifier | ClinicalTrials.gov 2026-09-20 04:36:53 | Détail |
| AQUA07 NCT07617337 · AQUA07 in Patients With ALK-Positive Non-Small Cell Lung Cancer | Cancer | À vérifier | Phase 1 | RECRUITING | This is a first-in-human, Phase I, open-label, multicenter, multinational… À vérifier | ClinicalTrials.gov 2026-09-20 04:36:52 | Détail |
| Cryotherapy NCT04248582 · Cryotherapy for Locally Advanced Esophageal Cancer | Cancer | Immunomodulation | Phase 1 | ACTIVE_NOT_RECRUITING | Background: In published studies, complete response (CR) to chemoradiation… À vérifier | ClinicalTrials.gov 2026-09-20 04:36:52 | Détail |
| Edetate Calcium Disodium NCT03630991 · Edetate Calcium Disodium or Succimer in Treating Patients With Acute Myeloid Leu… | Cancer | À vérifier | Phase 1 | RECRUITING | This phase I trial studies the side effects and best dose of edetate calci… À vérifier | ClinicalTrials.gov 2026-09-20 04:36:52 | Détail |
| GT719 Injection NCT06948981 · GT719 Injection for the Treatment of Recurrent/Refractory CD19 Positive Adult B-… | Cancer | À vérifier | Phase 1/2 | RECRUITING | This study is a prospective single-arm open-labled phase I/II clinical tri… À vérifier | ClinicalTrials.gov 2026-09-20 04:36:52 | Détail |
| JSB462 NCT07047118 · A Study of JSB462 (Luxdegalutamide) Plus Lutetium (177Lu) Vipivotide Tetraxetan… | Cancer | À vérifier | Phase 2 | ACTIVE_NOT_RECRUITING | This Phase II study aims to evaluate the efficacy and safety of the combin… À vérifier | ClinicalTrials.gov 2026-09-20 04:36:52 | Détail |
| modified FOLFIRINOX NCT07829185 · FALCON — Modified FOLFIRINOX and Pentamidine in Advanced and Metastatic Pancreat… | Cancer | À vérifier | Phase 1 | NOT_YET_RECRUITING | The purpose of this research is to observe the effects of using a new comb… À vérifier | ClinicalTrials.gov 2026-09-20 04:36:52 | Détail |
| Azacitidine NCT05554406 · Testing New Therapies for Patients With Acute Myeloid Leukemia Who Are Newly Dia… | Cancer | À vérifier | Phase 2 | RECRUITING | This phase II trial studies how well enasidenib and azacitidine work in tr… À vérifier | ClinicalTrials.gov 2026-09-20 04:36:51 | Détail |
| Biospecimen Collection NCT06058377 · Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy T… | Cancer | À vérifier | Phase 3 | RECRUITING | This phase III trial compares standard of care hormone therapy plus riboci… À vérifier | ClinicalTrials.gov 2026-09-20 04:36:51 | Détail |
| GammaTile® NCT07195591 · BRIDGES — Beginning Radiation Immediately With GammaTile at GBM Excision Versus… | Cancer | À vérifier | Phase 3 | RECRUITING | This is a Phase 3 prospective, randomized, superiority, open-label, multi-… À vérifier | ClinicalTrials.gov 2026-09-20 04:36:51 | Détail |
| Giredestrant NCT07827573 · kalitERA — A Study to Learn How Well Participants With a Specific Type of Early… | Cancer | À vérifier | Phase 3 | NOT_YET_RECRUITING | This study will evaluate the safety and efficacy of inavolisib combination… À vérifier | ClinicalTrials.gov 2026-09-20 04:36:51 | Détail |
| NBTXR3 NCT07224152 · NBTXR3 With Radiation Therapy Alone for Locally-advanced Non-small Cell Lung Can… | Cancer | À vérifier | Phase 1/2 | RECRUITING | This is a single institution, single arm phase I/II study of NBTXR3 with r… À vérifier | ClinicalTrials.gov 2026-09-20 04:36:51 | Détail |
| Stereotactic Radiosurgery NCT03508752 · Neurocognitive Decline in Patients With Brain Metastases | Cancer | À vérifier | Phase 1/2 | ACTIVE_NOT_RECRUITING | The phase I component of the study is to identify maximal tolerated dose (… À vérifier | ClinicalTrials.gov 2026-09-20 04:36:51 | Détail |
| Zilebesiran NCT07181109 · ZENITH — Zilebesiran in Patients With Hypertension Not Adequately Controlled and… | Hypertension artérielle | À vérifier | Phase 3 | RECRUITING | The purpose of this study is to evaluate the efficacy, pharmacodynamics (P… À vérifier | ClinicalTrials.gov 2026-09-20 04:36:45 | Détail |
| Atogepant 60 mg NCT07826910 · VOR-GRIP — Effect of Atogepant on the Vestibulo-Ocular Reflex in Healthy Adults… | Migraine | À vérifier | Phase 4 | NOT_YET_RECRUITING | This goal of this study is to compare three medications used for migraine… À vérifier | ClinicalTrials.gov 2026-09-20 04:36:35 | Détail |
| NEUROMARK System NCT06862674 · Clinical Exploration of NEUROMARK System in Participants With Chronic Migraine | Migraine | À vérifier | Non applicable | COMPLETED | Clinical exploration of NEUROMARK System in Participants with Chronic Migr… À vérifier | ClinicalTrials.gov 2026-09-20 04:36:35 | Détail |
| Neuromodulation Wearable Device NCT07642414 · A Comprehensive Digital Care Program for Migraine Management | Migraine | À vérifier | Non applicable | ENROLLING_BY_INVITATION | This study evaluates the clinical effectiveness of the Enso for Migraine p… À vérifier | ClinicalTrials.gov 2026-09-20 04:36:35 | Détail |
| Zavegepant NCT06401642 · Effectiveness and Tolerability of Zavegepant for Acute Migraine Treatment Among… | Migraine | À vérifier | Phase 4 | RECRUITING | Prospective, single-site, open-label, non-controlled pilot study consistin… À vérifier | ClinicalTrials.gov 2026-09-20 04:36:35 | Détail |
| NaviFUS System NCT06388707 · A Safety, Tolerability, and Preliminary Efficacy of Low-intensity Focused Ultras… | Épilepsie | À vérifier | Phase 1/2 | RECRUITING | Participants with drug-resistant epilepsy (DRE) enrolled in this study wil… À vérifier | ClinicalTrials.gov 2026-09-20 04:36:32 | Détail |
| RNS System NCT05339126 · RNS System LGS Feasibility Study | Épilepsie | À vérifier | Phase 2 | ACTIVE_NOT_RECRUITING | To generate preliminary safety and effectiveness data for brain-responsive… À vérifier | ClinicalTrials.gov 2026-09-20 04:36:32 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4595
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Effects of testosterone-augmented multimodal exercise intervention in… Whole-body Electrical Muscle Stimulation Exercise · PMID 41988780 | Myasthénie | À vérifier | Publication | PubMed | Voir la publication source Spinal cord injury (SCI) leads to profound muscle atrophy, aerobic deconditioning, and metabolic dysfunction. Exercise-… | The Journal of clinical endocrinology and metabolism 2026-09-20 04:37:05 | Source |
| Feasibility and acceptability of whole-body electromyostimulation in… Whole-body Electrical Muscle Stimulation Exercise · PMID 42464389 | Myasthénie | À vérifier | Publication | PubMed | Voir la publication source Evidence on the effectiveness of electromyostimulation (EMS) has been reported in pulmonary rehabilitation, but the ben… | Pilot and feasibility studies 2026-09-20 04:37:05 | Source |
| Vestibular contributions adapt to the balance strategies adopted duri… Whole-body Electrical Muscle Stimulation Exercise · PMID 42616645 | Myasthénie | À vérifier | Publication | PubMed | Voir la publication source Vestibular contributions during walking are not uniform, but vary with gait phase, muscle group, and balance demands. M… | Journal of neurophysiology 2026-09-20 04:37:05 | Source |
| Clinical efficacy of abdominal moxibustion at the Zhongji (CV3) in co… Yangyin Roujin Decoction · PMID 42015783 | Myopathies | Neuroprotection · Traitement symptomatique | Publication | PubMed | Voir la publication source To investigate the clinical effect of abdominal moxibustion at the Zhongji (CV3) combined with Yiqi Tonglin Yangyin dec… | Journal of traditional Chinese medicine = Chung i tsa… 2026-09-20 04:37:03 | Source |
| Yiqi Huoxue Yangyin Decoction Ameliorates Diabetic Nephropathy by Tar… Yangyin Roujin Decoction · PMID 42713045 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source This study aimed to investigate the protective effects and underlying mechanisms of Yiqi Huoxue Yangyin Decoction (YHY)… | Diabetes, metabolic syndrome and obesity : targets and… 2026-09-20 04:37:03 | Source |
| Yiqi Huoxue Yangyin Decoction attenuates diabetic nephropathy in mice… Yangyin Roujin Decoction · PMID 42016924 | Myopathies | Thérapie génique | Publication | PubMed | Voir la publication source Diabetic nephropathy (DN) is a major complication of diabetes with limited therapeutic options. Yiqi Huoxue Yangyin Dec… | Frontiers in pharmacology 2026-09-20 04:37:03 | Source |
| Barcoded oligonucleotide system (BOLT) for targeted organ delivery. Immunotherapy · PMID 42733790 | Cancer | À vérifier | Publication | PubMed | Voir la publication source The therapeutic potential of oligonucleotides (oligos) is limited by insufficient delivery to extrahepatic tissues. In… | Bioactive materials 2026-09-20 04:36:56 | Source |
| Dual metabolic checkpoint blockade a 3D-Printed metalloplatform remod… Immunotherapy · PMID 42724565 | Cancer | Immunomodulation | Publication | PubMed | Voir la publication source The immunosuppressive tumor microenvironment limits the efficacy of therapies that target metabolism. Here we show a st… | Bioactive materials 2026-09-20 04:36:56 | Source |
| Oligosaccharide adjuvant-deferred antigen endocytosis promotes cross-… Immunotherapy · PMID 42751513 | Cancer | Immunomodulation · Thérapie génique | Publication | PubMed | Voir la publication source Antigen cross-presentation by dendritic cells (DCs) is essential for inducing cytotoxic immune responses, which are cru… | Bioactive materials 2026-09-20 04:36:56 | Source |
| Feasibility and safety of early discharge after robot-assisted uro-on… Digital care pathway for hypertension · PMID 42671715 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source Early discharge after robot-assisted uro-oncologic surgery remains limited by concerns regarding patient safety and the… | Journal of robotic surgery 2026-09-20 04:36:49 | Source |
| HomeSafe: Postpartum Hypertensive Care Enabled by Electronic Health R… Digital care pathway for hypertension · PMID 41707683 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source The objective is to present stepwise refinements to , an Epic-tethered, population-health-coordinated postpartum pathwa… | American journal of perinatology 2026-09-20 04:36:49 | Source |
| Nutraceutical and functional food: efficacy against metabolic disorde… Digital care pathway for hypertension · PMID 42603698 | Hypertension artérielle | Neuroprotection · Immunomodulation | Publication | PubMed | Voir la publication source The growing global emphasis on health consciousness has significantly increased demand for traditional and complementar… | Journal of advanced research 2026-09-20 04:36:49 | Source |
| Community-engaged design of a virtual diabetes prevention program int… Asynchronous communication with nurse · PMID 42288862 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source The Diabetes Prevention Program (DPP) is an evidence-based approach to prevent Type 2 Diabetes (T2D), the leading cause… | BMC health services research 2026-09-20 04:36:48 | Source |
| Evolving Lung Cancer Navigator Practice Through Targeted Professional… Asynchronous communication with nurse · PMID 42463006 | Cancer | À vérifier | Publication | PubMed | Voir la publication source Lung cancer remains the leading cause of cancer deaths worldwide, and it has persistent disparities in detection, treat… | Chest 2026-09-20 04:36:48 | Source |
| Mass casualty training for prehospital and emergency providers in Kig… Asynchronous communication with nurse · PMID 42751142 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source A mass casualty incident (MCI) occurs when the number of patients exceeds available healthcare resources, placing signi… | African journal of emergency medicine : Revue africain… 2026-09-20 04:36:48 | Source |
| Innovating a Teach-Back Model for Community Health Workers Led Health… Health Literacy Project · PMID 40194526 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source From 2021 to 2023, the City of Albuquerque, the University of New Mexico (UNM) Office for Community Health, the UNM Hos… | Health literacy research and practice 2026-09-20 04:36:34 | Source |
| Carotid intima-media thickness may be an early biomarker for cardiova… Impact of Ketogenic Diets on Cardiovascular Health in Adults With Epilepsy · PMID 41026111 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source To assess early signs of atherosclerosis following long-term treatment with the ketogenic diet therapy due to concerns… | Epilepsia open 2026-09-20 04:36:33 | Source |
| Impact of low-carbohydrate diet on health status: an umbrella review. Impact of Ketogenic Diets on Cardiovascular Health in Adults With Epilepsy · PMID 39385794 | Cancer | À vérifier | Publication | PubMed | Voir la publication source The prevalence of diet-related non-communicable diseases has increased. A low-carbohydrate diet (LCDs) is one of the mo… | Frontiers in nutrition 2026-09-20 04:36:33 | Source |
| The effect of anti-seizure medications on lipid values in adults with… Impact of Ketogenic Diets on Cardiovascular Health in Adults With Epilepsy · PMID 37244221 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source Certain anti-seizure medications (ASMs) adversely impact lipid values. Here, we explored the impact of ASMs on lipid va… | Epilepsy & behavior : E&B 2026-09-20 04:36:33 | Source |
| Possible role of locus coeruleus neuronal loss in age-related memory… The Role of the Locus Coeruleus in Age-related Distractibility · PMID 37694113 | Maladie d’Alzheimer | Immunomodulation | Publication | PubMed | Voir la publication source Aging is associated with a decline in cognitive abilities, including memory and attention. It is generally accepted tha… | Frontiers in neuroscience 2026-09-20 04:36:30 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||