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Périmètre
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10635 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 5743
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Heart monitoring tools (data revision) NCT07008729 · RETENTION — Heart Failure Patient Management and Interventions Using Continuous… | Insuffisance cardiaque | À vérifier | Non applicable | ACTIVE_NOT_RECRUITING | The goal of this study is to create a digital platform for managing patien… À vérifier | ClinicalTrials.gov 2026-11-01 04:37:29 | Détail |
| Maridebart cafraglutide NCT07037459 · MARITIME-HF — Maridebart Cafraglutide in Heart Failure With Preserved or Mildly… | Insuffisance cardiaque | Traitement symptomatique | Phase 3 | RECRUITING | This trial will examine if maridebart cafraglutide as an adjunct to standa… À vérifier | ClinicalTrials.gov 2026-11-01 04:37:29 | Détail |
| Savagen (sacubitril/valsartan) NCT07907640 · Real-world Effectiveness and Safety of Savagen (Sacubitril/Valsartan) in Malaysi… | Insuffisance cardiaque | À vérifier | À vérifier | NOT_YET_RECRUITING | This multicentre, prospective, single-arm cohort study will evaluate the r… À vérifier | ClinicalTrials.gov 2026-11-01 04:37:29 | Détail |
| SmartECG-EF NCT07844434 · AI-Based Cardiac Analysis Using 12-Lead and 1-Lead ECG | Insuffisance cardiaque | À vérifier | À vérifier | RECRUITING | This pilot study is designed to evaluate the clinical performance and util… À vérifier | ClinicalTrials.gov 2026-11-01 04:37:29 | Détail |
| Tamibarotene NCT07855692 · The Clinical Trial of Tamibarotene for Patients With HFpEF (RELIEF Trial) | Insuffisance cardiaque | À vérifier | Phase 2 | RECRUITING | This study will evaluate the effect of 12 weeks of treatment with tamibaro… À vérifier | ClinicalTrials.gov 2026-11-01 04:37:29 | Détail |
| Adenosine NCT07898696 · Reducing Slow/No-Reflow With Prophylactic High-Dose Intracoronary Adenosine Prot… | Maladie coronarienne | À vérifier | Non applicable | RECRUITING | The REFLOW AMI Trial aims to determine whether prophylactic high-dose intr… À vérifier | ClinicalTrials.gov 2026-11-01 04:37:23 | Détail |
| Empagliflozin (SGLT2i) NCT07898709 · Evaluating SGLT2 Inhibitors for the Reduction of No-Reflow Phenomenon in Patient… | Maladie coronarienne | À vérifier | Phase 2 | NOT_YET_RECRUITING | Study Background \& Purpose: The no-reflow phenomenon is a significant com… À vérifier | ClinicalTrials.gov 2026-11-01 04:37:23 | Détail |
| Impella NCT06964685 · OASIS-AMICS — Assessment of Support With Impella® Best Practices in Acute Myocar… | Maladie coronarienne | À vérifier | À vérifier | RECRUITING | The observational study titled "Observational Assessment of Support with I… À vérifier | ClinicalTrials.gov 2026-11-01 04:37:23 | Détail |
| OCR-Prompt-LLM Information Extraction and Classification Workflow (OC… NCT07449429 · OCR-LLM-CHD — AI-Assisted Coronary Syndrome Subtyping From Admission History of… | Maladie coronarienne | À vérifier | À vérifier | COMPLETED | This study will evaluate whether an OCR-LLM-based clinical decision suppor… À vérifier | ClinicalTrials.gov 2026-11-01 04:37:23 | Détail |
| Vasopressor NCT04682483 · CSWG — Cardiogenic Shock Working Group Registry | Maladie coronarienne | À vérifier | À vérifier | RECRUITING | The Cardiogenic Shock Working Group is a multicenter registry where we col… À vérifier | ClinicalTrials.gov 2026-11-01 04:37:23 | Détail |
| Selatogrel NCT04957719 · SOS-AMI — Selatogrel Outcome Study in Suspected Acute Myocardial Infarction | Maladie coronarienne | À vérifier | Phase 3 | ENROLLING_BY_INVITATION | This study will randomize patients recently discharged from the hospital w… À vérifier | ClinicalTrials.gov 2026-11-01 04:37:22 | Détail |
| Selective C-reactive protein apheresis (PentraSorb®-CRP) NCT07687017 · CRP-SHOCK — CRP Apheresis in Infarct-Related Cardiogenic Shock | Maladie coronarienne | Immunomodulation | Non applicable | RECRUITING | Cardiogenic shock complicating acute myocardial infarction remains associa… À vérifier | ClinicalTrials.gov 2026-11-01 04:37:22 | Détail |
| Double-TAP post-dilatation NCT07872020 · SYMmetric Valve fraME Expansion To Reduce hYpoattenuated Leaflet Thickening Afte… | Maladie coronarienne | À vérifier | Non applicable | RECRUITING | Rationale: Transcatheter aortic valve implantation (TAVI) has become the s… À vérifier | ClinicalTrials.gov 2026-11-01 04:37:21 | Détail |
| F2 filter and delivery system NCT05866640 · Feasibility Trial of the F2 Filter and Delivery System for Embolic Protection Du… | Maladie coronarienne | Traitement symptomatique · Thérapie génique | Phase 1 | COMPLETED | The goal of this clinical trial is to learn about the safety and performan… À vérifier | ClinicalTrials.gov 2026-11-01 04:37:21 | Détail |
| HS235 NCT07123779 · HS235 Study in Overweight and Obese Participants With Combined Pre and Post-Capi… | Maladie coronarienne | À vérifier | Phase 1/2 | RECRUITING | Study of HS235 in Overweight and Obese Participants with Combined Pre and… À vérifier | ClinicalTrials.gov 2026-11-01 04:37:21 | Détail |
| Hydra THV NCT07566624 · HYSPANIA — Spanish Prospective Registry of Hydra THV for Transcatheter Aortic Va… | Maladie coronarienne | Traitement symptomatique | À vérifier | RECRUITING | This study is designed to evaluate the success rate of transfemoral implan… À vérifier | ClinicalTrials.gov 2026-11-01 04:37:21 | Détail |
| J-Valve Transfemoral System NCT07363473 · JOURNEY LVAD: JOURNEY Left Ventricular Assist Device | Maladie coronarienne | À vérifier | Non applicable | ACTIVE_NOT_RECRUITING | The objective of this study is to assess the safety and effectiveness of t… À vérifier | ClinicalTrials.gov 2026-11-01 04:37:21 | Détail |
| LBBAP implant NCT07254013 · LBBOT — Left Bundle Branch Area Pacing (LBBAP) Monitoring Assistant: Evaluation… | Maladie coronarienne | À vérifier | Non applicable | COMPLETED | To evaluate the capability to monitor LBB success criteria with the use of… À vérifier | ClinicalTrials.gov 2026-11-01 04:37:21 | Détail |
| pulsed-field ablation NCT05922917 · PIVCO — Pulsed-field Ablation in Patients With Persistent Atrial Fibrillation | Maladie coronarienne | À vérifier | Non applicable | COMPLETED | Since a new method called pulsed-field ablation (PFA) has emerged, allowin… À vérifier | ClinicalTrials.gov 2026-11-01 04:37:21 | Détail |
| Pulsed Field Ablation NCT06106594 · VOLT CE Mark Study | Maladie coronarienne | Traitement symptomatique | Non applicable | ACTIVE_NOT_RECRUITING | This clinical investigation is intended to demonstrate safety and effectiv… À vérifier | ClinicalTrials.gov 2026-11-01 04:37:21 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4871
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Effects of continuous vs. intermittent transcutaneous electrical stim… Transcutaneous electrical nerve stimulation unit (TENS) · PMID 41866984 | Maladie rénale chronique | Traitement symptomatique | Publication | PubMed | Voir la publication source To compare the effects of two transcutaneous electrical stimulation (TES) patterns applied to the auricular branches of… | Cranio : the journal of craniomandibular practice 2026-11-08 04:38:07 | Source |
| Optimizing Percutaneous Tibial Nerve Stimulation Intensity for Overac… Transcutaneous electrical nerve stimulation unit (TENS) · PMID 42554545 | Maladie rénale chronique | Traitement symptomatique | Publication | PubMed | Voir la publication source Overactive bladder (OAB) is a significant global health issue. The standard percutaneous tibial nerve stimulation (PTNS… | Neuromodulation : journal of the International Neuromo… 2026-11-08 04:38:07 | Source |
| Transcutaneous auricular vagus nerve stimulation improves dysautonomi… Transcutaneous electrical nerve stimulation unit (TENS) · PMID 42802247 | Maladie rénale chronique | Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source Autonomic nervous system dysfunction is highly prevalent in hypermobile Ehlers-Danlos syndrome (hEDS) and contributes s… | Neurological sciences : official journal of the Italia… 2026-11-08 04:38:07 | Source |
| Factors associated with high-flow therapy failure in COVID-19-related… Non-Invasive Positive Pressure Ventilation · PMID 42888091 | Maladie rénale chronique | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source The optimal selection of non-invasive respiratory support for patients with COVID-19-related acute hypoxemic respirator… | Enfermedades infecciosas y microbiologia clinica (Engl… 2026-11-08 04:38:06 | Source |
| High-Flow Nasal Cannula in Adult Acute Care: Physiological Mechanisms… Non-Invasive Positive Pressure Ventilation · PMID 42942512 | Maladie rénale chronique | À vérifier | Publication | PubMed | Voir la publication source High-flow nasal cannula (HFNC) oxygen therapy is widely used in emergency, intensive care, perioperative, and procedura… | Medicina (Kaunas, Lithuania) 2026-11-08 04:38:06 | Source |
| Impact of respiratory support on time to achieve full oral feeding in… Non-Invasive Positive Pressure Ventilation · PMID 42871336 | Maladie rénale chronique | À vérifier | Publication | PubMed | Voir la publication source Very low birth weight infants often require respiratory support, which may delay full oral feeding. The independent rol… | Frontiers in pediatrics 2026-11-08 04:38:06 | Source |
| A comparative analysis of 3MAX aspiration versus 3 mm Trevo Retriever… Thromboaspiration catheter · PMID 31243066 | Accident vasculaire cérébral | À vérifier | Publication | PubMed | Voir la publication source Although aspiration and stent retriever thrombectomy perform similarly in proximal occlusions, no comparative series ar… | Journal of neurointerventional surgery 2026-11-08 04:38:02 | Source |
| Percutaneous Pulmonary Thrombectomy Beyond Acute Pulmonary Embolism:… Thromboaspiration catheter · PMID 38385241 | Accident vasculaire cérébral | Thérapie génique | Publication | PubMed | Voir la publication source Subacute massive pulmonary embolism is an uncommon manifestation of severe pulmonary embolism associated with poor prog… | Journal of endovascular therapy : an official journal… 2026-11-08 04:38:02 | Source |
| Simplified classification of cavernous internal carotid artery tortuo… Thromboaspiration catheter · PMID 35475775 | Hypertension artérielle · Accident vasculaire cérébral | Thérapie génique | Publication | PubMed | Voir la publication source Thromboaspiration catheters are increasingly used for the endovascular treatment of large vessel stroke (LVS), while to… | Neurological research 2026-11-08 04:38:02 | Source |
| Multifocal continuous theta burst stimulation in idiopathic generaliz… Continuous Theta Burst Stimulation (cTBS) · PMID 42731195 | Accident vasculaire cérébral | Traitement symptomatique | Publication | PubMed | Voir la publication source Idiopathic generalized epilepsy (IGE) is a disorder of the cortico-subcortical networks. Continuous theta burst stimula… | Clinical neurophysiology : official journal of the Int… 2026-11-08 04:38:00 | Source |
| Optimizing brain functional-structural architecture with cTBS to redu… Continuous Theta Burst Stimulation (cTBS) · PMID 42457860 | Accident vasculaire cérébral | À vérifier | Publication | PubMed | Voir la publication source Alcohol use disorder (AUD) is characterized by high relapse rates, necessitating novel interventions. Continuous theta-… | Molecular psychiatry 2026-11-08 04:38:00 | Source |
| Digital Outreach to Improve Statin Refills in Patients With Low Stati… Cordio System · PMID 42667613 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Statin nonadherence is a leading, addressable driver of preventable cardiovascular events. Although health systems rout… | JAMA 2026-11-08 04:37:54 | Source |
| Endovascular ablation of the right greater splanchnic nerve for the m… Right Greater Splanchnic Nerve (GSN) ablation · PMID 42257781 | Insuffisance cardiaque | Traitement symptomatique | Publication | PubMed | Voir la publication source Heart failure with preserved ejection fraction (HFpEF) remains difficult to manage because conventional therapies often… | The Egyptian heart journal : (EHJ) : official bulletin… 2026-11-08 04:37:54 | Source |
| Incidence, medical therapy, and outcomes in heart failure with improv… Cordio System · PMID 42702264 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source To assess the incidence of heart failure with improved ejection fraction (HFimpEF) across guideline definitions (ACC/AH… | American heart journal 2026-11-08 04:37:54 | Source |
| Relationship Between the Azygos Vein and the Greater Splanchnic Nerve… Right Greater Splanchnic Nerve (GSN) ablation · PMID 42249803 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Although ablation of the greater splanchnic nerve is now being used to treat some patients with heart failure, the anat… | Clinical anatomy (New York, N.Y.) 2026-11-08 04:37:54 | Source |
| Validation of the PREVENT-HF Risk Prediction Equation in US Veterans. Cordio System · PMID 42969140 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Résumé non disponible dans la base locale. | Circulation 2026-11-08 04:37:54 | Source |
| Changes in right ventricular-pulmonary artery coupling after transcat… Tricuspid Transcatheter Edge-to-Edge Repair (TEER) · PMID 42822601 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Right ventricular-pulmonary artery (RV-PA) coupling is an established marker of prognosis in mitral regurgitation (MR),… | International journal of cardiology 2026-11-08 04:37:47 | Source |
| Intraprocedural evaluation of residual mitral and tricuspid regurgita… Tricuspid Transcatheter Edge-to-Edge Repair (TEER) · PMID 42982241 | Maladie coronarienne | À vérifier | Publication | PubMed | Voir la publication source Transcatheter edge-to-edge repair (TEER) has emerged as an established therapeutic option for selected patients with se… | International journal of cardiology 2026-11-08 04:37:47 | Source |
| Tricuspid transcatheter edge-to-edge repair versus transcatheter tric… Tricuspid Transcatheter Edge-to-Edge Repair (TEER) · PMID 42989943 | Maladie coronarienne | À vérifier | Publication | PubMed | Voir la publication source Recent clinical studies of tricuspid transcatheter edge-to-edge repair (T-TEER) and transcatheter tricuspid valve repla… | Current opinion in cardiology 2026-11-08 04:37:47 | Source |
| Automated Production of Gene-Edited CAR-T Cells for People Living wit… RAPA-501 Autologous T stem cells · PMID 42847201 | Cancer | Thérapie cellulaire · Thérapie génique | Publication | PubMed | Voir la publication source Adoptive transfer of gene-modified autologous T cells, for example, expressing chimeric antigen receptors (CARs), is a… | Human gene therapy 2026-11-08 04:37:39 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||