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Toutes les maladies
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Périmètre
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Chaque choix s’applique immédiatement aux quatre sections. Le filtre « type de SEP » n’apparaît que lorsque la sclérose en plaques est sélectionnée.
10635 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 5743
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Thermocoagulation (device) NCT02956239 · DELTA — Development, Field Testing and Evaluation of the Efficacy of a Hand-held… | Cancer | À vérifier | Non applicable | COMPLETED | This project develops, tests and produces a lightweight, cordless, battery… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:00 | Détail |
| Treatment by ablative treatment NCT04794660 · CESTA — The Study for the "Cervical Cancer Screening and Treatment Algorithms St… | Cancer | Thérapie génique | Phase 3 | UNKNOWN | The main objectives of CESTA are (1) to compare the efficacy of two cervic… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:00 | Détail |
| MRI-Guided Transurethral Ultrasound Ablation NCT05438563 · MRI-guided Transurethral Urethral Ultrasound Ablation for the Treatment of Low t… | Cancer | À vérifier | Non applicable | RECRUITING | This clinical trial tests whether the magnetic resonance imaging (MRI)-gui… À vérifier | ClinicalTrials.gov 2026-11-08 04:36:59 | Détail |
| VORTX Rx treatment NCT03741088 · Study to Evaluate VORTX Rx (Theresa) | Cancer | À vérifier | Non applicable | COMPLETED | Multi-center, Open-labeled, Non-randomized Study to Evaluate the Acute Tec… À vérifier | ClinicalTrials.gov 2026-11-08 04:36:59 | Détail |
| Belzutifan NCT04586231 · A Study of Belzutifan (MK-6482) in Combination With Lenvatinib Versus Cabozantin… | Cancer | Ralentissement de la progression | Phase 3 | ACTIVE_NOT_RECRUITING | The goal of this study is to evaluate the efficacy and safety of pembroliz… À vérifier | ClinicalTrials.gov 2026-11-08 04:36:58 | Détail |
| Capecitabine NCT05693766 · INSIGHT — Gene Signatures to Guide HR+MBC Therapy in a Diverse Cohort | Cancer | À vérifier | Phase 2 | RECRUITING | This is a phase 1/2, multicenter, open-label umbrella platform study that… À vérifier | ClinicalTrials.gov 2026-11-08 04:36:58 | Détail |
| EndoScell™ intraoperative handheld microscope NCT07029646 · Comparative Research on the Accuracy of Margin Interpretation in Breast-Conservi… | Cancer | À vérifier | Non applicable | COMPLETED | The goal of this clinical trial is to assess whether cell microscopic imag… À vérifier | ClinicalTrials.gov 2026-11-08 04:36:58 | Détail |
| Ipatasertib NCT05862285 · UmbrellaMAX — A Rollover Study for Participants Previously Enrolled in a Genente… | Cancer | À vérifier | Phase 3 | RECRUITING | This phase I/Ib trial tests the safety and best dose of ipatasertib in com… À vérifier | ClinicalTrials.gov 2026-11-08 04:36:58 | Détail |
| Talquetamab NCT06993675 · Engaging T-cells to Eliminate MRD in Newly Diagnosed Myeloma Optimizing Response… | Cancer | Immunomodulation | Phase 2 | RECRUITING | Myasthenia Gravis (MG) is a chronic autoimmune disease mediated by pathoge… À vérifier | ClinicalTrials.gov 2026-11-08 04:36:58 | Détail |
| YKST02 NCT07695740 · Study of YKST02 in Adults With Relapsed or Refractory Multiple Myeloma | Cancer | Ralentissement de la progression · Immunomodulation · Thérapie génique | Phase 2 | NOT_YET_RECRUITING | The goal of this Phase 2 clinical trial is to learn whether YKST02 is effe… À vérifier | ClinicalTrials.gov 2026-11-08 04:36:58 | Détail |
| Acalabrutinib NCT07582159 · Tafasitamab With Acalabrutinib and Venetoclax for the Treatment of Chronic Lymph… | Sclérose en plaques | À vérifier | Phase 2 | RECRUITING | The purpose of this study is to investigate the efficacy and safety of fix… À vérifier | ClinicalTrials.gov 2026-11-08 04:36:57 | Détail |
| Biospecimen Collection NCT01089101 · Selumetinib in Treating Young Patients With Recurrent or Refractory Low Grade Gl… | Cancer | À vérifier | Phase 1/2 | ACTIVE_NOT_RECRUITING | This phase III trial compares standard of care hormone therapy plus riboci… À vérifier | ClinicalTrials.gov 2026-11-08 04:36:57 | Détail |
| Carfilzomib NCT07715903 · Hepatic Artery Infusion of Carfilzomib in Participants With Liver Metastatic Dis… | Cancer | Thérapie génique | Phase 1 | NOT_YET_RECRUITING | The purpose of this study is to learn about the study medicine called elra… À vérifier | ClinicalTrials.gov 2026-11-08 04:36:57 | Détail |
| Colli-Pee 20 mL device with UCM NCT07902375 · MYSSELF — Methylation Profiling in Self-Samples for Identification of (Epi)Genet… | Cancer | À vérifier | Non applicable | RECRUITING | The goal of the MYSSELF (Methylation Profiling in Self-Samples for Identif… À vérifier | ClinicalTrials.gov 2026-11-08 04:36:57 | Détail |
| imotuzumab combined with the NALIRIFOX chemotherapy NCT07920731 · A Single-Arm Study of Nimotuzumab Combined With NALIRIFOX as First-Line Treatmen… | Cancer | Ralentissement de la progression | Phase 2 | ENROLLING_BY_INVITATION | This is a prospective, single-arm study in patients with locally advanced… À vérifier | ClinicalTrials.gov 2026-11-08 04:36:57 | Détail |
| INBRX-106 - Hexavalent OX40 agonist antibody NCT04198766 · Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) i… | Cancer | À vérifier | Phase 1/2 | RECRUITING | This is a Phase 1/2, open-label, non-randomized, 4-part trial to determine… À vérifier | ClinicalTrials.gov 2026-11-08 04:36:57 | Détail |
| Proton radiotherapy NCT07922967 · PRORADNOR-ReIR — Proton Re-irradiation in Patients With Recurrent or Second Prim… | Cancer | À vérifier | À vérifier | RECRUITING | Re-irradiation of head and neck cancer due to relaps or new cancer in the… À vérifier | ClinicalTrials.gov 2026-11-08 04:36:57 | Détail |
| Secukinumab Injection NCT07237594 · IL-17 Blockade to Decrease irAEs (REPLAY) | Cancer | À vérifier | Phase 1 | RECRUITING | The primary objective of this study is to determine the safety and feasibi… À vérifier | ClinicalTrials.gov 2026-11-08 04:36:57 | Détail |
| HEMI device NCT07604922 · STIMULUS-CKD — Investigating Vascular Properties of HEMI and SPG Signals in Indi… | Hypertension artérielle | À vérifier | Non applicable | RECRUITING | This prospective, single-center clinical investigation conducted in France… À vérifier | ClinicalTrials.gov 2026-11-08 04:36:50 | Détail |
| Syndemic-Adapted Medly Uganda (SAMU) NCT07525271 · SAMU — Trial Phase: Syndemic Adapted Medly Uganda | Hypertension artérielle | À vérifier | Non applicable | RECRUITING | The purpose of this study is to evaluate the effectiveness of the Syndemic… À vérifier | ClinicalTrials.gov 2026-11-08 04:36:50 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4871
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Effects of continuous vs. intermittent transcutaneous electrical stim… Transcutaneous electrical nerve stimulation unit (TENS) · PMID 41866984 | Maladie rénale chronique | Traitement symptomatique | Publication | PubMed | Voir la publication source To compare the effects of two transcutaneous electrical stimulation (TES) patterns applied to the auricular branches of… | Cranio : the journal of craniomandibular practice 2026-11-08 04:38:07 | Source |
| Optimizing Percutaneous Tibial Nerve Stimulation Intensity for Overac… Transcutaneous electrical nerve stimulation unit (TENS) · PMID 42554545 | Maladie rénale chronique | Traitement symptomatique | Publication | PubMed | Voir la publication source Overactive bladder (OAB) is a significant global health issue. The standard percutaneous tibial nerve stimulation (PTNS… | Neuromodulation : journal of the International Neuromo… 2026-11-08 04:38:07 | Source |
| Transcutaneous auricular vagus nerve stimulation improves dysautonomi… Transcutaneous electrical nerve stimulation unit (TENS) · PMID 42802247 | Maladie rénale chronique | Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source Autonomic nervous system dysfunction is highly prevalent in hypermobile Ehlers-Danlos syndrome (hEDS) and contributes s… | Neurological sciences : official journal of the Italia… 2026-11-08 04:38:07 | Source |
| Factors associated with high-flow therapy failure in COVID-19-related… Non-Invasive Positive Pressure Ventilation · PMID 42888091 | Maladie rénale chronique | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source The optimal selection of non-invasive respiratory support for patients with COVID-19-related acute hypoxemic respirator… | Enfermedades infecciosas y microbiologia clinica (Engl… 2026-11-08 04:38:06 | Source |
| High-Flow Nasal Cannula in Adult Acute Care: Physiological Mechanisms… Non-Invasive Positive Pressure Ventilation · PMID 42942512 | Maladie rénale chronique | À vérifier | Publication | PubMed | Voir la publication source High-flow nasal cannula (HFNC) oxygen therapy is widely used in emergency, intensive care, perioperative, and procedura… | Medicina (Kaunas, Lithuania) 2026-11-08 04:38:06 | Source |
| Impact of respiratory support on time to achieve full oral feeding in… Non-Invasive Positive Pressure Ventilation · PMID 42871336 | Maladie rénale chronique | À vérifier | Publication | PubMed | Voir la publication source Very low birth weight infants often require respiratory support, which may delay full oral feeding. The independent rol… | Frontiers in pediatrics 2026-11-08 04:38:06 | Source |
| A comparative analysis of 3MAX aspiration versus 3 mm Trevo Retriever… Thromboaspiration catheter · PMID 31243066 | Accident vasculaire cérébral | À vérifier | Publication | PubMed | Voir la publication source Although aspiration and stent retriever thrombectomy perform similarly in proximal occlusions, no comparative series ar… | Journal of neurointerventional surgery 2026-11-08 04:38:02 | Source |
| Percutaneous Pulmonary Thrombectomy Beyond Acute Pulmonary Embolism:… Thromboaspiration catheter · PMID 38385241 | Accident vasculaire cérébral | Thérapie génique | Publication | PubMed | Voir la publication source Subacute massive pulmonary embolism is an uncommon manifestation of severe pulmonary embolism associated with poor prog… | Journal of endovascular therapy : an official journal… 2026-11-08 04:38:02 | Source |
| Simplified classification of cavernous internal carotid artery tortuo… Thromboaspiration catheter · PMID 35475775 | Hypertension artérielle · Accident vasculaire cérébral | Thérapie génique | Publication | PubMed | Voir la publication source Thromboaspiration catheters are increasingly used for the endovascular treatment of large vessel stroke (LVS), while to… | Neurological research 2026-11-08 04:38:02 | Source |
| Multifocal continuous theta burst stimulation in idiopathic generaliz… Continuous Theta Burst Stimulation (cTBS) · PMID 42731195 | Accident vasculaire cérébral | Traitement symptomatique | Publication | PubMed | Voir la publication source Idiopathic generalized epilepsy (IGE) is a disorder of the cortico-subcortical networks. Continuous theta burst stimula… | Clinical neurophysiology : official journal of the Int… 2026-11-08 04:38:00 | Source |
| Optimizing brain functional-structural architecture with cTBS to redu… Continuous Theta Burst Stimulation (cTBS) · PMID 42457860 | Accident vasculaire cérébral | À vérifier | Publication | PubMed | Voir la publication source Alcohol use disorder (AUD) is characterized by high relapse rates, necessitating novel interventions. Continuous theta-… | Molecular psychiatry 2026-11-08 04:38:00 | Source |
| Digital Outreach to Improve Statin Refills in Patients With Low Stati… Cordio System · PMID 42667613 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Statin nonadherence is a leading, addressable driver of preventable cardiovascular events. Although health systems rout… | JAMA 2026-11-08 04:37:54 | Source |
| Endovascular ablation of the right greater splanchnic nerve for the m… Right Greater Splanchnic Nerve (GSN) ablation · PMID 42257781 | Insuffisance cardiaque | Traitement symptomatique | Publication | PubMed | Voir la publication source Heart failure with preserved ejection fraction (HFpEF) remains difficult to manage because conventional therapies often… | The Egyptian heart journal : (EHJ) : official bulletin… 2026-11-08 04:37:54 | Source |
| Incidence, medical therapy, and outcomes in heart failure with improv… Cordio System · PMID 42702264 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source To assess the incidence of heart failure with improved ejection fraction (HFimpEF) across guideline definitions (ACC/AH… | American heart journal 2026-11-08 04:37:54 | Source |
| Relationship Between the Azygos Vein and the Greater Splanchnic Nerve… Right Greater Splanchnic Nerve (GSN) ablation · PMID 42249803 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Although ablation of the greater splanchnic nerve is now being used to treat some patients with heart failure, the anat… | Clinical anatomy (New York, N.Y.) 2026-11-08 04:37:54 | Source |
| Validation of the PREVENT-HF Risk Prediction Equation in US Veterans. Cordio System · PMID 42969140 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Résumé non disponible dans la base locale. | Circulation 2026-11-08 04:37:54 | Source |
| Changes in right ventricular-pulmonary artery coupling after transcat… Tricuspid Transcatheter Edge-to-Edge Repair (TEER) · PMID 42822601 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Right ventricular-pulmonary artery (RV-PA) coupling is an established marker of prognosis in mitral regurgitation (MR),… | International journal of cardiology 2026-11-08 04:37:47 | Source |
| Intraprocedural evaluation of residual mitral and tricuspid regurgita… Tricuspid Transcatheter Edge-to-Edge Repair (TEER) · PMID 42982241 | Maladie coronarienne | À vérifier | Publication | PubMed | Voir la publication source Transcatheter edge-to-edge repair (TEER) has emerged as an established therapeutic option for selected patients with se… | International journal of cardiology 2026-11-08 04:37:47 | Source |
| Tricuspid transcatheter edge-to-edge repair versus transcatheter tric… Tricuspid Transcatheter Edge-to-Edge Repair (TEER) · PMID 42989943 | Maladie coronarienne | À vérifier | Publication | PubMed | Voir la publication source Recent clinical studies of tricuspid transcatheter edge-to-edge repair (T-TEER) and transcatheter tricuspid valve repla… | Current opinion in cardiology 2026-11-08 04:37:47 | Source |
| Automated Production of Gene-Edited CAR-T Cells for People Living wit… RAPA-501 Autologous T stem cells · PMID 42847201 | Cancer | Thérapie cellulaire · Thérapie génique | Publication | PubMed | Voir la publication source Adoptive transfer of gene-modified autologous T cells, for example, expressing chimeric antigen receptors (CARs), is a… | Human gene therapy 2026-11-08 04:37:39 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||