Traitements14programmes
Essais12liés
Publications0liées
SourceDBlocale

Traitements

14
MoléculeIndication / populationPhaseObjectifPaysRésultat
ErlotinibThis study is to determine the use of theophylline in patients with NSCLC and advanced solid malignancies and whether treatment with theophylline will help lower or diminish the side effect of diarrhea in patients taking erlotinib. Patients will be enrolled in one of two parts of the study to verify the lowest dose of theophylline that is effective and the highest dose of erlotinib that can be tolerated with theophylline. If this study shows that theophylline is able to inhibit erlotinib induced diarrhea, it will help demonstrate that patients using the tyrosine kinase inhibitor (TKIs), erlotinib, can use it effectively at higher doses without experiencing severe diarrhea. SEP Phase 1 À vérifier Canada À vérifier
TheophyllineTo evaluate the effect of multiple doses of BIIL 284 BS on the pharmacokinetics of a single dose of theophylline. SEP Phase 1 À vérifier Canada À vérifier
TheophyllineTo evaluate the effect of multiple doses of BIIL 284 BS on the pharmacokinetics of a single dose of theophylline. SEP Non applicable À vérifier China À vérifier
TheophyllineTo evaluate the effect of multiple doses of BIIL 284 BS on the pharmacokinetics of a single dose of theophylline. SEP Phase 4 À vérifier China À vérifier
TheophyllineTo evaluate the effect of multiple doses of BIIL 284 BS on the pharmacokinetics of a single dose of theophylline. SEP Phase 4 À vérifier United States À vérifier
TheophyllineTo evaluate the effect of multiple doses of BIIL 284 BS on the pharmacokinetics of a single dose of theophylline. SEP Non applicable À vérifier Spain À vérifier
TheophyllineTo evaluate the effect of multiple doses of BIIL 284 BS on the pharmacokinetics of a single dose of theophylline. SEP Non applicable À vérifier Israel À vérifier
TheophyllineTo evaluate the effect of multiple doses of BIIL 284 BS on the pharmacokinetics of a single dose of theophylline. SEP Phase 3 À vérifier United States À vérifier
TheophyllineTo evaluate the effect of multiple doses of BIIL 284 BS on the pharmacokinetics of a single dose of theophylline. SEP Phase 2 À vérifier United States À vérifier
TheophyllineTo evaluate the effect of multiple doses of BIIL 284 BS on the pharmacokinetics of a single dose of theophylline. SEP Non applicable À vérifier Finland À vérifier
TheophyllineTo evaluate the effect of multiple doses of BIIL 284 BS on the pharmacokinetics of a single dose of theophylline. SEP Phase 2/3 À vérifier Canada À vérifier
TheophyllineTo evaluate the effect of multiple doses of BIIL 284 BS on the pharmacokinetics of a single dose of theophylline. SEP Phase 4 À vérifier United States À vérifier
TheophyllineTo evaluate the effect of multiple doses of BIIL 284 BS on the pharmacokinetics of a single dose of theophylline. SEP Phase 4 À vérifier Australia À vérifier
TheophyllineTo evaluate the effect of multiple doses of BIIL 284 BS on the pharmacokinetics of a single dose of theophylline. SEP Phase 1 À vérifier Canada À vérifier

Essais cliniques

12
MoléculeIndication / populationPhaseNCTTitreStatut
Theophylline SEP Phase 1 NCT02080078 A Phase I Dose Escalation Study of Erlotinib in Combination With Theophylline TERMINATED
Theophylline SEP Phase 4 NCT02261727 TASCS — Theophylline and Steroids in Chronic Obstructive Pulmonary Disease (COPD) Study COMPLETED
Theophylline SEP Phase 4 NCT01601132 Drug Interaction Study of Colchicine and Theophylline COMPLETED
Theophylline SEP Phase 2/3 NCT01066728 CO2 Inhalation as a New Treatment Modality for Apnea of Prematurity COMPLETED
Theophylline SEP Non applicable NCT03115294 CardiomeDIC — Digital Image Correlation in Right Ventricular Evaluation COMPLETED
Theophylline SEP Phase 2 NCT04551170 Theophylline Treatment for Pseudohypoparathyroidism - Children 2-12 Years Old ACTIVE_NOT_RECRUITING
Theophylline SEP Phase 3 NCT02340520 Enhancement of Corticosteroid Efficacy in COPD COMPLETED
Theophylline SEP Non applicable NCT00893009 The Effect on Small Airways of Addition of Theophylline as Inducer of Histone Deacilase Activity for Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD), Treated With Inhaled Steroids and Long Acting Beta Agonists UNKNOWN
Theophylline SEP Non applicable NCT00671151 Effects of Low-Dose Theophylline During Chronic Obstructive Pulmonary Disease (COPD) Exacerbations COMPLETED
Theophylline SEP Phase 4 NCT03718403 Effect of Theophylline in Pseudohypoparathyroidism RECRUITING
Theophylline SEP Phase 4 NCT01684683 The Effect of Theophylline in the Treatment of Bronchiectasis COMPLETED
Theophylline SEP Non applicable NCT02001935 Association Between CytochromeP4501A2 and CytochromeP4502E1 Gene Polymorphisms and Metabolism of Theophylline COMPLETED

Publications

0
MoléculeIndication / populationTitreJournalDate
Aucune publication.