Vue transversale de la maladie
Migraine
Un même point d’entrée pour les études cliniques, les découvertes scientifiques, les publications et les pistes exploratoires présentes dans Biomedical Watch.
Périmètre
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1305 résultats correspondants
· 46 visibles sur cette page
dans le périmètre Migraine
Niveau clinique
Études et traitements 623
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Dexmedetomidine NCT07926542 · DEX-EBUS — Dexmedetomidine as an add-on Sedative for Endobronchial Ultrasound | Cancer | Traitement symptomatique · Thérapie génique | Non applicable | COMPLETED | Migraine is a debilitating neurological disorder characterized by recurren… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:53 | Détail |
| Topical solution of 4% lidocaine NCT07764783 · VISION — Visual Instillation of Sphenopalatine-block Intervention for ONgoing Mi… | Migraine | Traitement symptomatique | Phase 2 | NOT_YET_RECRUITING | The goal of this double-blinded, randomized placebo controlled clinical tr… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:41 | Détail |
| Acupuncture NCT07888777 · Manual Acupuncture for Intradialytic Nausea and Vomiting in Patients Undergoing… | Maladie rénale chronique | À vérifier | Non applicable | NOT_YET_RECRUITING | The goal of this clinical trial is to determine the effectiveness of Tai C… À vérifier | ClinicalTrials.gov 2026-11-08 04:38:03 | Détail |
| Cryoneurolysis NCT05444361 · Ultrasound-Guided Percutaneous Cryoneurolysis to Treat Postoperative Pain After… | Cancer | Traitement symptomatique | Non applicable | ENROLLING_BY_INVITATION | The trial is a research study that tests a freezing technique called cryon… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:00 | Détail |
| Lidocaine Hydrochloride NCT06462781 · LIGHT 1 — Localized Injection of Lidocaine and Glucocorticoid for Headache Treat… | Migraine | Traitement symptomatique | Phase 1 | COMPLETED | This randomized clinical trial will aim to compare the effectiveness of dr… À vérifier | ClinicalTrials.gov 2026-11-08 04:36:45 | Détail |
| Elismetrep NCT07674654 · A Long-Term Safety Study of Elismetrep (K-304) in the Acute Treatment of Migraine | Migraine | À vérifier | Phase 3 | RECRUITING | This is a long-term safety study to evaluate the safety and tolerability o… À vérifier | ClinicalTrials.gov 2026-11-08 04:36:39 | Détail |
| Elismetrep NCT07645924 · A Study to Evaluate the Efficacy and Safety of Elismetrep (K-304) in the Acute T… | Migraine | À vérifier | Phase 3 | RECRUITING | This is a long-term safety study to evaluate the safety and tolerability o… À vérifier | ClinicalTrials.gov 2026-11-08 04:36:39 | Détail |
| Elismetrep NCT07816367 · A Study to Assess the Efficacy and Safety of Elismetrep (K-304) in the Acute Tre… | Migraine | À vérifier | Phase 3 | RECRUITING | This is a long-term safety study to evaluate the safety and tolerability o… À vérifier | ClinicalTrials.gov 2026-11-08 04:36:39 | Détail |
| Eptinezumab 100 mg or Eptinezumab 300 mg administered intravenously i… NCT07916571 · Migraine Menopause Study | Migraine | À vérifier | Phase 4 | NOT_YET_RECRUITING | The object of this study is to assess the effectiveness, safety, and toler… À vérifier | ClinicalTrials.gov 2026-11-08 04:36:39 | Détail |
| EVO756, Dose 1 NCT07616128 · Study of EVO756 in Adults With Migraine | Migraine | À vérifier | Phase 2 | RECRUITING | This study will evaluate the efficacy and safety of EVO756 against placebo… À vérifier | ClinicalTrials.gov 2026-11-08 04:36:39 | Détail |
| Middle Meningeal Artery embolization NCT06735833 · MMA Embolization for Refractory Chronic Migraine | Migraine | À vérifier | Non applicable | ACTIVE_NOT_RECRUITING | This is a prospective, multi-center, feasibility study to investigate safe… À vérifier | ClinicalTrials.gov 2026-11-08 04:36:39 | Détail |
| UB-313 NCT05477095 · A Phase 1 Study to Evaluate the Safety, Tolerability, and Immunogenicity of UB-3… | Migraine | À vérifier | Phase 1 | COMPLETED | This first in-human (FIH) study of UB-313, an anti-calcitonin gene-related… À vérifier | ClinicalTrials.gov 2026-11-08 04:36:39 | Détail |
| K-645 100 mg NCT07116499 · A Study of K-645 in the Treatment of Multiple Migraine Attacks | Migraine | À vérifier | Phase 2 | TERMINATED | This is a multicenter, randomized, double-blind, placebo-controlled, 3-per… À vérifier | ClinicalTrials.gov 2026-11-08 04:36:38 | Détail |
| Nitroglycerin 0.3 MG NCT05907655 · Study of the Glymphatic System in Migraine | Migraine | À vérifier | À vérifier | RECRUITING | This study aimed to investigate the role of the glymphatic system in the i… À vérifier | ClinicalTrials.gov 2026-11-08 04:36:38 | Détail |
| Rimegepant 75 mg ODT NCT07918053 · NIGHTCAP — A Prospective Study of Rimegepant for Short-term Preventive Treatment… | Migraine | À vérifier | Non applicable | NOT_YET_RECRUITING | This is a multicenter, single-arm, open-label Phase 4 study evaluating the… À vérifier | ClinicalTrials.gov 2026-11-08 04:36:38 | Détail |
| transcranial direct stimulation NCT06468189 · MIRAGE — Clinical and Neurophysiological Effects of tDCS to Visual and Motor Cor… | Migraine | Traitement symptomatique · Thérapie génique | Non applicable | ACTIVE_NOT_RECRUITING | tDCS can be offered as an alternative to migraine patients who have freque… À vérifier | ClinicalTrials.gov 2026-11-08 04:36:38 | Détail |
| Antiepileptic Drug NCT07903168 · Epi-IRIS — Why Do People With Epilepsy Get More Infections? | Épilepsie | À vérifier | À vérifier | NOT_YET_RECRUITING | People with epilepsy are predisposed to having seizures ("fits"), where ab… À vérifier | ClinicalTrials.gov 2026-11-08 04:36:35 | Détail |
| Cryoneurolysis NCT07303582 · ICE — Individualised Cryoneurolysis to Treat Pain in the Context of Spasticity i… | Sclérose en plaques | Traitement symptomatique | Phase 4 | RECRUITING | The trial is a research study that tests a freezing technique called cryon… À vérifier | ClinicalTrials.gov 2026-11-08 04:36:05 | Détail |
| Fentanyl Étude non communiquée | Cancer · Migraine | À vérifier | Non applicable | Terminé | Migraine attacks were frequently diagnosed in the emergency departments. A… À vérifier | ClinicalTrials.gov 2026-11-05 | Détail |
| Saline 0.9% Étude non communiquée | Migraine | Traitement symptomatique | Phase 2 | Prévu | The goal of this double-blinded, randomized placebo controlled clinical tr… À vérifier | ClinicalTrials.gov 2026-11-04 | Détail |
Découverte scientifique
Recherches et trouvailles 0
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune trouvaille ne correspond aux filtres. | |||||||
Bibliographie
Publications 676
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Synergistic Modification of Polylactic Acid Fibrous Membranes with Im… Glycerol Tributyrate · PMID 40254794 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Reusable and biodegradable facemasks with enhanced antibacterial and mechanical functions are considered sustainable pe… | ACS applied materials & interfaces 2026-08-16 19:24:34 | Source |
| Efficacy of acupuncture therapies for polycystic ovary syndrome: a ne… fire needling combined with filiform needling · PMID 42591356 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Polycystic ovary syndrome (PCOS) is a prevalent gynecological disorder that significantly impairs quality of life and r… | Frontiers in medicine 2026-08-16 19:24:33 | Source |
| Refractory Periungual Warts Treated with Filiform Fire Needle Combine… fire needling combined with filiform needling · PMID 42226748 | Migraine | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Periungual warts, caused by Human Papillomavirus (HPV) infection, are a therapeutic challenge due to their proximity to… | Clinical, cosmetic and investigational dermatology 2026-08-16 19:24:33 | Source |
| ['s experience in treatment of knee osteoarthritis with 's filiform f… fire needling combined with filiform needling · PMID 41987451 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source This paper introduces the clinical experience of Professor in treatment of knee osteoarthritis (KOA) using "'s filiform… | Zhongguo zhen jiu = Chinese acupuncture & moxibustion 2026-08-16 19:24:33 | Source |
| Investigating the effects of chlorogenic acid on novel object recogni… Ketamine · PMID 42571303 | Migraine | Neuroprotection · Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source Schizophrenia is a severe neuropsychiatric disorder characterized by positive, negative, cognitive, mood-related, and m… | IBRO neuroscience reports 2026-08-16 19:24:32 | Source |
| Ketamine preserves perineuronal nets in chronic stressed mice brain t… Ketamine · PMID 42571376 | Migraine | Immunomodulation | Publication | PubMed | Voir la publication source Deeper understanding of ketamine's mechanism of action would contribute to the discovery of novel therapeutic targets w… | IBRO neuroscience reports 2026-08-16 19:24:32 | Source |
| Pediatric Acupuncture Safety: A Scoping Review. filiform needling · PMID 42179706 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Previous research studies have indicated that acupuncture may be a promising treatment for several pediatric conditions… | Global advances in integrative medicine and health 2026-08-16 19:24:32 | Source |
| Substance use and mental health outcomes among gay and bisexual men i… Ketamine · PMID 42494974 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source This study investigated the prevalence of substance use among gay and bisexual men in South Korea and examined its asso… | Addictive behaviors reports 2026-08-16 19:24:32 | Source |
| [Long-term clinical effect of fire needling on knee osteoarthritis]. filiform needling · PMID 42116777 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source To observe the long-term clinical efficacy and safety of fire needling in the treatment of knee osteoarthritis. Sixty p… | Zhongguo zhen jiu = Chinese acupuncture & moxibustion 2026-08-16 19:24:32 | Source |
| Ditan Decoction alleviates glutamate excitotoxicity in an Aβ-induced… ditan · PMID 42320774 | Migraine | Neuroprotection | Publication | PubMed | Voir la publication source Alzheimer's disease (AD), as the most prevalent form of dementia among the elders, poses a major global health challeng… | Journal of ethnopharmacology 2026-08-16 19:24:28 | Source |
| Impact of antiviral treatment and initiation time on mother-to-child… ditan · PMID 42003011 | Migraine | À vérifier | Publication | PubMed | Voir la publication source To further reduce mother-to-child transmission (MTCT), this study aims to explore the factors influencing MTCT rate in… | Virulence 2026-08-16 19:24:28 | Source |
| Impact of midwife-led continuous support during childbirth on materna… ditan · PMID 42373140 | Migraine | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source To evaluate the association between integrated midwife-led continuous labor support with postpartum care and maternal a… | The journal of maternal-fetal & neonatal medicine : th… 2026-08-16 19:24:28 | Source |
| Effectiveness and safety of sumatriptan 85 mg/naproxen sodium 500 mg… combination of sumatriptan and naproxen · PMID 42591283 | Migraine | Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source This prospective multicenter observational study, designed by the Greek Research Alliance for the Study of Headache and… | Frontiers in neurology 2026-08-16 19:24:27 | Source |
| CGRP: the immune system's double agent - context-dependent roles in i… anti-CGRP monoclonal antibodies · PMID 42488654 | Migraine | Immunomodulation | Publication | PubMed | Voir la publication source Calcitonin gene-related peptide (CGRP) is traditionally recognized as a key mediator of nociception and vasodilation. H… | Frontiers in immunology 2026-08-16 19:24:26 | Source |
| Perceived comfort with migraine treatments and control of migraine sy… gepants · PMID 42517716 | Migraine | Ralentissement de la progression · Traitement symptomatique | Publication | PubMed | Voir la publication source This study was conducted to identify patient characteristics and medication factors associated with perceived comfort w… | Headache 2026-08-16 19:24:26 | Source |
| STS101 nasal powder as a new treatment option for acute migraine with… gepants · PMID 42217235 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Although effective acute migraine therapies are available, unmet treatment needs such as nausea, vomiting, or delayed g… | Expert review of neurotherapeutics 2026-08-16 19:24:26 | Source |
| Cobalt-induced charge redistribution and lattice distortion enable ac… Eptinezumab 100 or 300 mg ev · PMID 42335689 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Cation substitution provides an effective route to regulate electrochemical kinetics in NASICON-type cathodes, yet the… | Journal of colloid and interface science 2026-08-16 19:24:25 | Source |
| High-temperature reversible emission in a simple Schiff base: activat… Eptinezumab 100 or 300 mg ev · PMID 42348974 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Thermally robust solid-state emission remains rare among simple organic chromophores because elevated temperature usual… | Spectrochimica acta. Part A, Molecular and biomolecula… 2026-08-16 19:24:25 | Source |
| Integrated multispectroscopic and DFT analysis of molecular heterogen… Eptinezumab 100 or 300 mg ev · PMID 42349151 | Migraine | À vérifier | Publication | PubMed | Voir la publication source This study presents the first systematic analysis of the molecular architecture of asphaltenes isolated from Garabagh p… | Spectrochimica acta. Part A, Molecular and biomolecula… 2026-08-16 19:24:25 | Source |
| Targeting the PACAP-38 pathway is an emerging therapeutic strategy fo… Lu AG09222 · PMID 38337150 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source The pituitary adenylate cyclase-activating polypeptide-38 (PACAP-38) has emerged as a key mediator of migraine pathogen… | Expert opinion on emerging drugs 2026-08-16 19:24:23 | Source |
Exploration — prudence
Pistes exploratoires 6
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Bavisant BRAVEinMS — Bavisant | Migraine | Remyélinisation · Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Antagonisme du récepteur H3 de l’histamine Bavisant est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migra… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| Tol-MP Tol-MP — tolérance immunitaire spécifique de la myéline | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Microparticules biodégradables chargées en rapamycine et fonctionnalisées… Tol-MP est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migrain… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| C-CAR168 C-CAR168 — AbelZeta Pharma | Migraine | Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | CAR-T autologue bispécifique anti-CD20/BCMA visant une déplétion profonde… C-CAR168 est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migra… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| SetPoint System SetPoint System — SetPoint Medical | Migraine | Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | nceFuture ApplicationsPublicationsCompanyCareersNewsGet startedGet started… SetPoint System est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pou… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation immunométabolique de la microglie 4-octyl itaconate et dérivés est étudié dans Sclérose latérale amyotrophique et documente plusieurs axes biologiques po… | Rapprochement Biomedical Watch · Sclérose latérale amy… | Détail |
| N-PPG N-PPG — modulation métabolique cérébrale | Migraine | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation métabolique et mitohormèse N-PPG est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être pertinents pour Migrai… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |