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Toutes les maladies
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Périmètre
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10635 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 5743
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| TranspoCART19 NCT07799116 · CART-NEL — Study to Evaluate the Safety and Preliminary Efficacy of CD19 CAR-T C… | Lupus | Thérapie cellulaire | Phase 1/2 | RECRUITING | The goal of this clinical trial is to evaluate the safety and preliminary… À vérifier | ClinicalTrials.gov 2026-10-04 04:36:57 | Détail |
| SNUH-CD19-CAR-T Cells NCT07855302 · CD19 CAR-T Therapy for Refractory Childhood-Onset Systemic Lupus Erythematosus | Lupus | Immunomodulation · Thérapie cellulaire | Phase 1 | RECRUITING | This study is evaluating the safety and potential benefits of CD19 chimeri… À vérifier | ClinicalTrials.gov 2026-10-04 04:36:56 | Détail |
| Dapirolizumab pegol NCT04976322 · A Study to Evaluate the Safety and Tolerability of Dapirolizumab Pegol in Study… | Lupus | À vérifier | Phase 3 | ENROLLING_BY_INVITATION | The purpose of this study is to evaluate long-term safety and tolerability… À vérifier | ClinicalTrials.gov 2026-10-04 04:36:55 | Détail |
| Echocardiography-guided transthoracic radio frequency ablation for HO… NCT02888132 · Echocardiography-guided Transthoracic Radio Frequency/Laser Ablation for Ventric… | Cancer | Traitement symptomatique | Non applicable | UNKNOWN | Hypertrophic Obstructive Cardiomyopathy (HOCM) patients have significant c… À vérifier | ClinicalTrials.gov 2026-10-04 04:36:52 | Détail |
| 5G-Enabled Remote Robotic-Assisted Bronchoscopy-Guided Cryoablation NCT07830095 · 5G-Enabled Remote Robotic-Assisted Bronchoscopy-Guided Cryoablation for Pulmonar… | Cancer | À vérifier | Non applicable | NOT_YET_RECRUITING | The purpose of the study is to evaluate the technical feasibility of 5G-en… À vérifier | ClinicalTrials.gov 2026-10-04 04:36:51 | Détail |
| Branch Chain Amino Acid NCT03908255 · BCAA in HCC — Branched-chain Amino Acid Supplementation for Hepatocellular Carci… | Cancer | Ralentissement de la progression | Phase 2 | WITHDRAWN | Hepatocellular carcinoma (HCC) is the fifth most common cause of cancer de… À vérifier | ClinicalTrials.gov 2026-10-04 04:36:51 | Détail |
| EUS-guided RFA NCT03221335 · EUS-guided RFA for Solid Abdominal Neoplasms | Cancer | À vérifier | Non applicable | RECRUITING | Radiofrequency ablation has been used for treatment of solid neoplasms of… À vérifier | ClinicalTrials.gov 2026-10-04 04:36:51 | Détail |
| IP-001 NCT03993678 · Intratumoral Injection of IP-001 Following Thermal Ablation in Patients With Adv… | Cancer | Ralentissement de la progression | Phase 1/2 | COMPLETED | The therapeutic approach taken by trial SAKK 66/17 is different from those… À vérifier | ClinicalTrials.gov 2026-10-04 04:36:51 | Détail |
| Irreversible Electroporation NCT06185556 · COLDFIRE-III Trial: Efficacy of Irreversible Electroporation and Stereotactic Bo… | Cancer | Traitement symptomatique · Thérapie génique | Phase 2/3 | RECRUITING | Up to 16 patients with confirmed low- or intermediate risk prostate cancer… À vérifier | ClinicalTrials.gov 2026-10-04 04:36:51 | Détail |
| Multi-mode thermal ablation device NCT06307080 · Clinical Study of Multimodal Ablation Remodeling Immunosensitized PD-1 in the Tr… | Cancer | À vérifier | Non applicable | RECRUITING | 1. Clinical evaluation of multimodal ablation system for pancreatic cancer… À vérifier | ClinicalTrials.gov 2026-10-04 04:36:51 | Détail |
| Poseidon System NCT04087980 · Ablation of Prostate Tissue Utilizing Sterile Water Vapor in Patients With Inter… | Cancer | À vérifier | Non applicable | COMPLETED | The purpose of this research study is to collect information on a new trea… À vérifier | ClinicalTrials.gov 2026-10-04 04:36:51 | Détail |
| Surgical electrocautery (ECA) NCT02615860 · TECAIN — Efficacy and Safety of TCA vs. ECA for the Treatment of AIN in HIV-posi… | Cancer | À vérifier | Non applicable | COMPLETED | Comparative evaluation of efficacy and safety of high-resolution anoscopy… À vérifier | ClinicalTrials.gov 2026-10-04 04:36:51 | Détail |
| Visudyne NCT02464761 · Photodynamic Therapy for the Treatment of Vertebral Metastases | Cancer | Traitement symptomatique | Phase 1 | COMPLETED | An estimated 10 percent of primary breast, prostate, lung, thyroid and ren… À vérifier | ClinicalTrials.gov 2026-10-04 04:36:51 | Détail |
| Sonablate HIFU device NCT03620786 · HIFU for Focal Ablation of Prostate Tissue: An Observational Study | Cancer | À vérifier | À vérifier | RECRUITING | The Sonablate HIFU device was approved by the U.S.FDA for prostate tissue… À vérifier | ClinicalTrials.gov 2026-10-04 04:36:50 | Détail |
| UFOGUIDE "patient transducer" NCT04803773 · UFOGUIDE — MRI-guided Focused Ultrasound : Feasibility Study for the Treatment o… | Cancer | À vérifier | Non applicable | UNKNOWN | Ufoguide is a prospective single arm open study to assess the feasibility… À vérifier | ClinicalTrials.gov 2026-10-04 04:36:50 | Détail |
| Montanide (Registered Trademark) ISA-51 VG Adjuvant NCT05642195 · Evaluation of a Cancer Lysate Vaccine and Montanide (Registered Trademark) ISA-5… | Cancer | À vérifier | Phase 1/2 | SUSPENDED | Background: Surgery is the primary treatment for non-small cell lung cance… À vérifier | ClinicalTrials.gov 2026-10-04 04:36:49 | Détail |
| AZD6244 NCT01362803 · AZD6244 Hydrogen Sulfate for Children With Nervous System Tumors | Cancer | À vérifier | Phase 1/2 | ACTIVE_NOT_RECRUITING | Background: \- Plexiform neurofibromas are tumors that grow in and around… À vérifier | ClinicalTrials.gov 2026-10-04 04:36:48 | Détail |
| BAT8008 injection NCT06341114 · A Clinical Study Evaluating the Safety, Tolerability, Pharmacokinetic Characteri… | Cancer | À vérifier | Phase 1/2 | ACTIVE_NOT_RECRUITING | The study, led by Zhejiang Cancer Hospital and sponsored by Bio-Thera Solu… À vérifier | ClinicalTrials.gov 2026-10-04 04:36:48 | Détail |
| CD30.CAR-EBVST cells NCT04288726 · Allogeneic CD30.CAR-EBVSTs in Patients With Relapsed or Refractory CD30-Positive… | Cancer | Immunomodulation · Thérapie génique | Phase 1 | ACTIVE_NOT_RECRUITING | This study involved patients that have a cancer called diffuse large B cel… À vérifier | ClinicalTrials.gov 2026-10-04 04:36:48 | Détail |
| Enfortumab vedotin NCT04995419 · A Study to Evaluate Enfortumab Vedotin (ASG-22CE) in Chinese Participants With L… | Cancer | Traitement symptomatique | Phase 2 | COMPLETED | This study is being done to see how well two drugs (enfortumab vedotin and… À vérifier | ClinicalTrials.gov 2026-10-04 04:36:48 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4871
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Effects of continuous vs. intermittent transcutaneous electrical stim… Transcutaneous electrical nerve stimulation unit (TENS) · PMID 41866984 | Maladie rénale chronique | Traitement symptomatique | Publication | PubMed | Voir la publication source To compare the effects of two transcutaneous electrical stimulation (TES) patterns applied to the auricular branches of… | Cranio : the journal of craniomandibular practice 2026-11-08 04:38:07 | Source |
| Optimizing Percutaneous Tibial Nerve Stimulation Intensity for Overac… Transcutaneous electrical nerve stimulation unit (TENS) · PMID 42554545 | Maladie rénale chronique | Traitement symptomatique | Publication | PubMed | Voir la publication source Overactive bladder (OAB) is a significant global health issue. The standard percutaneous tibial nerve stimulation (PTNS… | Neuromodulation : journal of the International Neuromo… 2026-11-08 04:38:07 | Source |
| Transcutaneous auricular vagus nerve stimulation improves dysautonomi… Transcutaneous electrical nerve stimulation unit (TENS) · PMID 42802247 | Maladie rénale chronique | Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source Autonomic nervous system dysfunction is highly prevalent in hypermobile Ehlers-Danlos syndrome (hEDS) and contributes s… | Neurological sciences : official journal of the Italia… 2026-11-08 04:38:07 | Source |
| Factors associated with high-flow therapy failure in COVID-19-related… Non-Invasive Positive Pressure Ventilation · PMID 42888091 | Maladie rénale chronique | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source The optimal selection of non-invasive respiratory support for patients with COVID-19-related acute hypoxemic respirator… | Enfermedades infecciosas y microbiologia clinica (Engl… 2026-11-08 04:38:06 | Source |
| High-Flow Nasal Cannula in Adult Acute Care: Physiological Mechanisms… Non-Invasive Positive Pressure Ventilation · PMID 42942512 | Maladie rénale chronique | À vérifier | Publication | PubMed | Voir la publication source High-flow nasal cannula (HFNC) oxygen therapy is widely used in emergency, intensive care, perioperative, and procedura… | Medicina (Kaunas, Lithuania) 2026-11-08 04:38:06 | Source |
| Impact of respiratory support on time to achieve full oral feeding in… Non-Invasive Positive Pressure Ventilation · PMID 42871336 | Maladie rénale chronique | À vérifier | Publication | PubMed | Voir la publication source Very low birth weight infants often require respiratory support, which may delay full oral feeding. The independent rol… | Frontiers in pediatrics 2026-11-08 04:38:06 | Source |
| A comparative analysis of 3MAX aspiration versus 3 mm Trevo Retriever… Thromboaspiration catheter · PMID 31243066 | Accident vasculaire cérébral | À vérifier | Publication | PubMed | Voir la publication source Although aspiration and stent retriever thrombectomy perform similarly in proximal occlusions, no comparative series ar… | Journal of neurointerventional surgery 2026-11-08 04:38:02 | Source |
| Percutaneous Pulmonary Thrombectomy Beyond Acute Pulmonary Embolism:… Thromboaspiration catheter · PMID 38385241 | Accident vasculaire cérébral | Thérapie génique | Publication | PubMed | Voir la publication source Subacute massive pulmonary embolism is an uncommon manifestation of severe pulmonary embolism associated with poor prog… | Journal of endovascular therapy : an official journal… 2026-11-08 04:38:02 | Source |
| Simplified classification of cavernous internal carotid artery tortuo… Thromboaspiration catheter · PMID 35475775 | Hypertension artérielle · Accident vasculaire cérébral | Thérapie génique | Publication | PubMed | Voir la publication source Thromboaspiration catheters are increasingly used for the endovascular treatment of large vessel stroke (LVS), while to… | Neurological research 2026-11-08 04:38:02 | Source |
| Multifocal continuous theta burst stimulation in idiopathic generaliz… Continuous Theta Burst Stimulation (cTBS) · PMID 42731195 | Accident vasculaire cérébral | Traitement symptomatique | Publication | PubMed | Voir la publication source Idiopathic generalized epilepsy (IGE) is a disorder of the cortico-subcortical networks. Continuous theta burst stimula… | Clinical neurophysiology : official journal of the Int… 2026-11-08 04:38:00 | Source |
| Optimizing brain functional-structural architecture with cTBS to redu… Continuous Theta Burst Stimulation (cTBS) · PMID 42457860 | Accident vasculaire cérébral | À vérifier | Publication | PubMed | Voir la publication source Alcohol use disorder (AUD) is characterized by high relapse rates, necessitating novel interventions. Continuous theta-… | Molecular psychiatry 2026-11-08 04:38:00 | Source |
| Digital Outreach to Improve Statin Refills in Patients With Low Stati… Cordio System · PMID 42667613 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Statin nonadherence is a leading, addressable driver of preventable cardiovascular events. Although health systems rout… | JAMA 2026-11-08 04:37:54 | Source |
| Endovascular ablation of the right greater splanchnic nerve for the m… Right Greater Splanchnic Nerve (GSN) ablation · PMID 42257781 | Insuffisance cardiaque | Traitement symptomatique | Publication | PubMed | Voir la publication source Heart failure with preserved ejection fraction (HFpEF) remains difficult to manage because conventional therapies often… | The Egyptian heart journal : (EHJ) : official bulletin… 2026-11-08 04:37:54 | Source |
| Incidence, medical therapy, and outcomes in heart failure with improv… Cordio System · PMID 42702264 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source To assess the incidence of heart failure with improved ejection fraction (HFimpEF) across guideline definitions (ACC/AH… | American heart journal 2026-11-08 04:37:54 | Source |
| Relationship Between the Azygos Vein and the Greater Splanchnic Nerve… Right Greater Splanchnic Nerve (GSN) ablation · PMID 42249803 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Although ablation of the greater splanchnic nerve is now being used to treat some patients with heart failure, the anat… | Clinical anatomy (New York, N.Y.) 2026-11-08 04:37:54 | Source |
| Validation of the PREVENT-HF Risk Prediction Equation in US Veterans. Cordio System · PMID 42969140 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Résumé non disponible dans la base locale. | Circulation 2026-11-08 04:37:54 | Source |
| Changes in right ventricular-pulmonary artery coupling after transcat… Tricuspid Transcatheter Edge-to-Edge Repair (TEER) · PMID 42822601 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Right ventricular-pulmonary artery (RV-PA) coupling is an established marker of prognosis in mitral regurgitation (MR),… | International journal of cardiology 2026-11-08 04:37:47 | Source |
| Intraprocedural evaluation of residual mitral and tricuspid regurgita… Tricuspid Transcatheter Edge-to-Edge Repair (TEER) · PMID 42982241 | Maladie coronarienne | À vérifier | Publication | PubMed | Voir la publication source Transcatheter edge-to-edge repair (TEER) has emerged as an established therapeutic option for selected patients with se… | International journal of cardiology 2026-11-08 04:37:47 | Source |
| Tricuspid transcatheter edge-to-edge repair versus transcatheter tric… Tricuspid Transcatheter Edge-to-Edge Repair (TEER) · PMID 42989943 | Maladie coronarienne | À vérifier | Publication | PubMed | Voir la publication source Recent clinical studies of tricuspid transcatheter edge-to-edge repair (T-TEER) and transcatheter tricuspid valve repla… | Current opinion in cardiology 2026-11-08 04:37:47 | Source |
| Automated Production of Gene-Edited CAR-T Cells for People Living wit… RAPA-501 Autologous T stem cells · PMID 42847201 | Cancer | Thérapie cellulaire · Thérapie génique | Publication | PubMed | Voir la publication source Adoptive transfer of gene-modified autologous T cells, for example, expressing chimeric antigen receptors (CARs), is a… | Human gene therapy 2026-11-08 04:37:39 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||