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8841 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 4225
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Expressive Writing for the Management of Stress in Cancer Survivors NCT04776941 · NCT04776941 | Cancer | Thérapie génique | Non applicable | RECRUITING | This clinical trial evaluates the effect of expressive writing for the man… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:36 | Détail |
| Oxaliplatin, 5FU, leucovorin NCT07062536 · mFOLFOX/mFOLFIRI vs. mFOLFOX in Advanced or Recurrent Biliary Tract Cancer Secon… | Cancer | À vérifier | Phase 2 | RECRUITING | In second line with advanced or recurrent biliary tract cancer refractory… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:36 | Détail |
| PF-06821497 NCT06629779 · A Study to Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic Ca… | Cancer | À vérifier | Phase 3 | RECRUITING | This study will explore whether a combination of the investigational drug… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:36 | Détail |
| PROMOTE — Gene Expression in Patients With Metastatic Prostate Cancer… NCT01953640 · NCT01953640 | Cancer | Thérapie génique | À vérifier | COMPLETED | This research trial studies gene expression in patients with prostate canc… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:36 | Détail |
| Rilvegostomig NCT06627647 · A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for… | Cancer | Ralentissement de la progression | Phase 3 | RECRUITING | DESTINY-Endometrial01 will investigate the efficacy of first-line T-DXd +… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:36 | Détail |
| Supra Inguinal Fascia Iliaca Block Versus Ultrasound-guided Caudal An… NCT07056946 · NCT07056946 | Cancer | À vérifier | Non applicable | COMPLETED | patients will then be randomized in the two groups. 1. Group C: in this gr… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:36 | Détail |
| Telisotuzumab Adizutecan NCT06772623 · Study to Evaluate Adverse Events and Efficacy of Intravenous (IV) Telisotuzumab… | Cancer | À vérifier | Phase 1/2 | RECRUITING | Non small cell lung carcinoma (NSCLC) is the most frequently occurring his… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:36 | Détail |
| Anti-CD40 Agonist Monoclonal Antibody CDX-1140 NCT05231122 · Pembrolizumab Combined With Bevacizumab With or Without Agonist Anti-CD40 CDX-11… | Cancer | Traitement symptomatique | Phase 2 | RECRUITING | This phase II trial tests whether pembrolizumab combined with bevacizumab… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:35 | Détail |
| Elranatamab NCT06152575 · MagnetisMM-32: A Study to Learn About the Study Medicine Called Elranatamab in P… | Cancer | Thérapie génique | Phase 3 | RECRUITING | The purpose of this study is to learn about the study medicine called elra… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:35 | Détail |
| flexible AIR coil NCT05043012 · Diagnostic Performance Of Non-Endorectal Coil Multiparametric Magnetic Resonance… | Cancer | À vérifier | Non applicable | RECRUITING | Multiparametric MRI (mpMRI) of the prostate is an important tool for diagn… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:35 | Détail |
| Hemanext ONE system NCT06685848 · Comparison of Hemanext ONE® System and Conventional Red Blood Cell Transfusion | Cancer | À vérifier | Non applicable | ACTIVE_NOT_RECRUITING | The overall objective of this study is to collect preliminary effectivenes… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:35 | Détail |
| PROACTION: — Investigations of Reproductive Cancers in Women NCT06527157 · NCT06527157 | Cancer | À vérifier | À vérifier | RECRUITING | The goal of this study is to create a non-invasive diagnostic test to rule… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:35 | Détail |
| HPV ctDNA Response based radiation NCT07425054 · CHART-AC — ctHPVDNA Response-Adapted Chemoradiation +/- Retifanlimab Treatment i… | Cancer | À vérifier | Phase 2 | RECRUITING | This study is for people who have anal cancer and have not yet had treatme… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:34 | Détail |
| Hydrocortisone NCT07763210 · Lazarus: IT Therapy for ICANS | Cancer | Ralentissement de la progression · Thérapie génique | Phase 2 | NOT_YET_RECRUITING | The purpose of this study is to assess the efficacy and safety of opevesos… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:34 | Détail |
| IMPACT STREAM — Master Framework For Relapse or Refractory Acute Myel… NCT06459024 · NCT06459024 | Cancer | À vérifier | À vérifier | RECRUITING | This is an observational (non-interventional), prospective, cohort study t… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:34 | Détail |
| Post-operative radiotherapy NCT06878274 · RESCUE — Post-operative Radiotherapy After Neodjuvant Chemo-immunotherapy and Su… | Cancer | À vérifier | Phase 2 | RECRUITING | This study investigates whether postoperative radiotherapy (PORT) improves… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:34 | Détail |
| Tislelizumab NCT05758116 · Tislelizumab Consolidation Therapy After Radiotherapy or Sequential Chemoradiati… | Cancer | À vérifier | Phase 2 | COMPLETED | The current standard of care for locally advanced non-small cell lung canc… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:34 | Détail |
| Biopsy Procedure NCT03502733 · Testing the Combination of Copanlisib, Nivolumab and Ipilimumab in Patients With… | Cancer | À vérifier | Phase 1 | ACTIVE_NOT_RECRUITING | This phase I/II trial studies the side effects and best dose of pidnarulex… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:33 | Détail |
| Inotuzumab ozogamicin NCT05748171 · A Study to Learn More About the Study Medicine Called Inotuzumab Ozogamicin (InO… | Cancer | À vérifier | Phase 2 | RECRUITING | This prospective, randomized, multicenter, open-label Phase 2 study is des… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:33 | Détail |
| PF-07799544 NCT05538130 · A Study to Learn About the Study Medicine Called PF-07799544 as Monotherapy or i… | Cancer | Thérapie génique | Phase 1 | RECRUITING | The purpose of this clinical trial is to learn the safety and effects of t… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:33 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4595
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Effects of testosterone-augmented multimodal exercise intervention in… Whole-body Electrical Muscle Stimulation Exercise · PMID 41988780 | Myasthénie | À vérifier | Publication | PubMed | Voir la publication source Spinal cord injury (SCI) leads to profound muscle atrophy, aerobic deconditioning, and metabolic dysfunction. Exercise-… | The Journal of clinical endocrinology and metabolism 2026-09-20 04:37:05 | Source |
| Feasibility and acceptability of whole-body electromyostimulation in… Whole-body Electrical Muscle Stimulation Exercise · PMID 42464389 | Myasthénie | À vérifier | Publication | PubMed | Voir la publication source Evidence on the effectiveness of electromyostimulation (EMS) has been reported in pulmonary rehabilitation, but the ben… | Pilot and feasibility studies 2026-09-20 04:37:05 | Source |
| Vestibular contributions adapt to the balance strategies adopted duri… Whole-body Electrical Muscle Stimulation Exercise · PMID 42616645 | Myasthénie | À vérifier | Publication | PubMed | Voir la publication source Vestibular contributions during walking are not uniform, but vary with gait phase, muscle group, and balance demands. M… | Journal of neurophysiology 2026-09-20 04:37:05 | Source |
| Clinical efficacy of abdominal moxibustion at the Zhongji (CV3) in co… Yangyin Roujin Decoction · PMID 42015783 | Myopathies | Neuroprotection · Traitement symptomatique | Publication | PubMed | Voir la publication source To investigate the clinical effect of abdominal moxibustion at the Zhongji (CV3) combined with Yiqi Tonglin Yangyin dec… | Journal of traditional Chinese medicine = Chung i tsa… 2026-09-20 04:37:03 | Source |
| Yiqi Huoxue Yangyin Decoction Ameliorates Diabetic Nephropathy by Tar… Yangyin Roujin Decoction · PMID 42713045 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source This study aimed to investigate the protective effects and underlying mechanisms of Yiqi Huoxue Yangyin Decoction (YHY)… | Diabetes, metabolic syndrome and obesity : targets and… 2026-09-20 04:37:03 | Source |
| Yiqi Huoxue Yangyin Decoction attenuates diabetic nephropathy in mice… Yangyin Roujin Decoction · PMID 42016924 | Myopathies | Thérapie génique | Publication | PubMed | Voir la publication source Diabetic nephropathy (DN) is a major complication of diabetes with limited therapeutic options. Yiqi Huoxue Yangyin Dec… | Frontiers in pharmacology 2026-09-20 04:37:03 | Source |
| Barcoded oligonucleotide system (BOLT) for targeted organ delivery. Immunotherapy · PMID 42733790 | Cancer | À vérifier | Publication | PubMed | Voir la publication source The therapeutic potential of oligonucleotides (oligos) is limited by insufficient delivery to extrahepatic tissues. In… | Bioactive materials 2026-09-20 04:36:56 | Source |
| Dual metabolic checkpoint blockade a 3D-Printed metalloplatform remod… Immunotherapy · PMID 42724565 | Cancer | Immunomodulation | Publication | PubMed | Voir la publication source The immunosuppressive tumor microenvironment limits the efficacy of therapies that target metabolism. Here we show a st… | Bioactive materials 2026-09-20 04:36:56 | Source |
| Oligosaccharide adjuvant-deferred antigen endocytosis promotes cross-… Immunotherapy · PMID 42751513 | Cancer | Immunomodulation · Thérapie génique | Publication | PubMed | Voir la publication source Antigen cross-presentation by dendritic cells (DCs) is essential for inducing cytotoxic immune responses, which are cru… | Bioactive materials 2026-09-20 04:36:56 | Source |
| Feasibility and safety of early discharge after robot-assisted uro-on… Digital care pathway for hypertension · PMID 42671715 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source Early discharge after robot-assisted uro-oncologic surgery remains limited by concerns regarding patient safety and the… | Journal of robotic surgery 2026-09-20 04:36:49 | Source |
| HomeSafe: Postpartum Hypertensive Care Enabled by Electronic Health R… Digital care pathway for hypertension · PMID 41707683 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source The objective is to present stepwise refinements to , an Epic-tethered, population-health-coordinated postpartum pathwa… | American journal of perinatology 2026-09-20 04:36:49 | Source |
| Nutraceutical and functional food: efficacy against metabolic disorde… Digital care pathway for hypertension · PMID 42603698 | Hypertension artérielle | Neuroprotection · Immunomodulation | Publication | PubMed | Voir la publication source The growing global emphasis on health consciousness has significantly increased demand for traditional and complementar… | Journal of advanced research 2026-09-20 04:36:49 | Source |
| Community-engaged design of a virtual diabetes prevention program int… Asynchronous communication with nurse · PMID 42288862 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source The Diabetes Prevention Program (DPP) is an evidence-based approach to prevent Type 2 Diabetes (T2D), the leading cause… | BMC health services research 2026-09-20 04:36:48 | Source |
| Evolving Lung Cancer Navigator Practice Through Targeted Professional… Asynchronous communication with nurse · PMID 42463006 | Cancer | À vérifier | Publication | PubMed | Voir la publication source Lung cancer remains the leading cause of cancer deaths worldwide, and it has persistent disparities in detection, treat… | Chest 2026-09-20 04:36:48 | Source |
| Mass casualty training for prehospital and emergency providers in Kig… Asynchronous communication with nurse · PMID 42751142 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source A mass casualty incident (MCI) occurs when the number of patients exceeds available healthcare resources, placing signi… | African journal of emergency medicine : Revue africain… 2026-09-20 04:36:48 | Source |
| Innovating a Teach-Back Model for Community Health Workers Led Health… Health Literacy Project · PMID 40194526 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source From 2021 to 2023, the City of Albuquerque, the University of New Mexico (UNM) Office for Community Health, the UNM Hos… | Health literacy research and practice 2026-09-20 04:36:34 | Source |
| Carotid intima-media thickness may be an early biomarker for cardiova… Impact of Ketogenic Diets on Cardiovascular Health in Adults With Epilepsy · PMID 41026111 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source To assess early signs of atherosclerosis following long-term treatment with the ketogenic diet therapy due to concerns… | Epilepsia open 2026-09-20 04:36:33 | Source |
| Impact of low-carbohydrate diet on health status: an umbrella review. Impact of Ketogenic Diets on Cardiovascular Health in Adults With Epilepsy · PMID 39385794 | Cancer | À vérifier | Publication | PubMed | Voir la publication source The prevalence of diet-related non-communicable diseases has increased. A low-carbohydrate diet (LCDs) is one of the mo… | Frontiers in nutrition 2026-09-20 04:36:33 | Source |
| The effect of anti-seizure medications on lipid values in adults with… Impact of Ketogenic Diets on Cardiovascular Health in Adults With Epilepsy · PMID 37244221 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source Certain anti-seizure medications (ASMs) adversely impact lipid values. Here, we explored the impact of ASMs on lipid va… | Epilepsy & behavior : E&B 2026-09-20 04:36:33 | Source |
| Possible role of locus coeruleus neuronal loss in age-related memory… The Role of the Locus Coeruleus in Age-related Distractibility · PMID 37694113 | Maladie d’Alzheimer | Immunomodulation | Publication | PubMed | Voir la publication source Aging is associated with a decline in cognitive abilities, including memory and attention. It is generally accepted tha… | Frontiers in neuroscience 2026-09-20 04:36:30 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||