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10635 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 5743
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Early intervention for OMI NCT06570759 · DIFOCCULT-3 — Time for a Diagnostic Paradigm Shift From STEMI/NSTEMI to OMI/NOMI | Maladie coronarienne | À vérifier | Non applicable | COMPLETED | The investigators hypothesize that occlusion myocardial infarction(MI)/non… À vérifier | ClinicalTrials.gov 2026-10-18 04:37:27 | Détail |
| Colchicine 0.5 MG Oral Tablet NCT04774159 · LEADER-PAD — Low Dose ColchicinE in pAtients With Peripheral Artery DiseasE to A… | Maladie coronarienne | Ralentissement de la progression · Immunomodulation | Phase 3 | RECRUITING | The goal of this clinical trial is to evaluate whether low-dose colchicine… À vérifier | ClinicalTrials.gov 2026-10-18 04:37:26 | Détail |
| Percutaneous Coronary Intervention (PCI) NCT02038127 · GWPCI — Gangwon PCI Prospective Registry | Maladie coronarienne | À vérifier | À vérifier | RECRUITING | This prospective, multicenter registry will consecutively enroll patients… À vérifier | ClinicalTrials.gov 2026-10-18 04:37:26 | Détail |
| Selective CRP apheresis using the PentraSorb®-CRP system NCT04939805 · CRP Apheresis in STEMI | Maladie coronarienne | Immunomodulation | Non applicable | RECRUITING | Background: In patients with acute ST-elevation myocardial infarction (STE… À vérifier | ClinicalTrials.gov 2026-10-18 04:37:26 | Détail |
| Xolatryp NCT07362446 · PROTECT-MI — Prevention of Reperfusion Injury Outcomes Through Effective Cardiop… | Maladie coronarienne | À vérifier | Phase 2 | RECRUITING | This study is open to adults with ST elevation myocardial infarction (hear… À vérifier | ClinicalTrials.gov 2026-10-18 04:37:26 | Détail |
| Bisoprolol Oral Tablet NCT06562582 · STAMI-BAS — STunning in Acute Myocardial Infarction - BAS | Maladie coronarienne | À vérifier | Phase 4 | RECRUITING | The objective of this trial is to examine the effect of immediate versus l… À vérifier | ClinicalTrials.gov 2026-10-18 04:37:25 | Détail |
| Conventional Treatment group NCT07867197 · CR MI FC — Effectiveness of Digital Cardiac Rehabilitation on Functional Capacit… | Maladie coronarienne | Thérapie génique | Non applicable | RECRUITING | The goal of this clinical trial is to learn if a digital health-supported… À vérifier | ClinicalTrials.gov 2026-10-18 04:37:25 | Détail |
| Coronary and peripheral stents NCT04573660 · AV-MDR — Abbott Vascular Medical Device Registry | Maladie coronarienne | À vérifier | À vérifier | RECRUITING | The AV-MDR is a prospective, non-randomized, open-label, multi-center regi… À vérifier | ClinicalTrials.gov 2026-10-18 04:37:25 | Détail |
| Impella 5.5 SmartAssist NCT06965504 · INTeGRATE — INitiation and Titration of Guideline Directed Medical TheRApy in He… | Maladie coronarienne | À vérifier | Non applicable | RECRUITING | The study will evaluate the impact of a combined device-drug strategy with… À vérifier | ClinicalTrials.gov 2026-10-18 04:37:25 | Détail |
| Use of OCT to guide the angioplasty procedure NCT04391413 · DOCTORS-LM — Does OCT Optimise Results of Stenting on the Left Main Stem | Maladie coronarienne | À vérifier | Non applicable | COMPLETED | The DOCTORS-LM study will investigate the impact of using optical coherenc… À vérifier | ClinicalTrials.gov 2026-10-18 04:37:25 | Détail |
| OCT-guided PCI NCT06154395 · Study on the Improvement of Myocardial Microcirculation After Acute Anterior Myo… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This study is a prospective, single-center, randomized controlled clinical… À vérifier | ClinicalTrials.gov 2026-10-18 04:37:24 | Détail |
| Ablation procedure with DuoVT PFA system NCT07706712 · EXACT-VT — Evaluation of the DuoVT PFA System for Ventricular Tachycardia | Maladie coronarienne | À vérifier | Non applicable | RECRUITING | This study is a prospective, non-randomized, single-arm, multicenter study… À vérifier | ClinicalTrials.gov 2026-10-18 04:37:23 | Détail |
| Active Colchicine NCT03310125 · Colchicine For The Prevention Of Perioperative Atrial Fibrillation In Patients U… | Maladie coronarienne | Immunomodulation | Phase 3 | COMPLETED | The prevention of perioperative atrial fibrillation (AF) and myocardial in… À vérifier | ClinicalTrials.gov 2026-10-18 04:37:23 | Détail |
| aktivplan NCT07878520 · ACTIVE-CaRe — Effectiveness of the "Aktivplan" Digital Intervention for Supporti… | Maladie coronarienne | Thérapie génique | Non applicable | NOT_YET_RECRUITING | After a cardiac event like a heart attack or heart surgery, regular heart-… À vérifier | ClinicalTrials.gov 2026-10-18 04:37:23 | Détail |
| Bachmann's Bundle Pacing NCT07874763 · BACH-RAP — Bachmann's Bundle Versus Right Atrial Appendage Pacing | Maladie coronarienne | À vérifier | Non applicable | RECRUITING | Participants will be randomly assigned to one of two clinical treatment Ar… À vérifier | ClinicalTrials.gov 2026-10-18 04:37:23 | Détail |
| CPAP therapy NCT04712656 · Effects of CPAP Therapy on Blood Pressure and Heart Rate Variability in Obstruct… | Maladie coronarienne | Traitement symptomatique | À vérifier | ACTIVE_NOT_RECRUITING | The primary objective of this study is to determine whether the effect of… À vérifier | ClinicalTrials.gov 2026-10-18 04:37:23 | Détail |
| elamipretide NCT04689360 · An Intermediate Size Expanded Access Protocol of Elamipretide | Maladie coronarienne | Thérapie génique | À vérifier | AVAILABLE | Choosing to participate in an expanded access program is an important pers… À vérifier | ClinicalTrials.gov 2026-10-18 04:37:23 | Détail |
| LAAC NCT03409159 · Austrian Left Atrial Appendage Closure Registry | Maladie coronarienne | À vérifier | À vérifier | RECRUITING | Left atrial appendage (LAA) occlusion (LAAC) has been introduced to treat… À vérifier | ClinicalTrials.gov 2026-10-18 04:37:23 | Détail |
| oCRH NCT00001452 · Defining the Genetic Basis for the Development of Primary Pigmented Nodular Adre… | Maladie coronarienne | À vérifier | À vérifier | COMPLETED | Lentiginosis refers to groups of diseases marked by the presence of pigmen… À vérifier | ClinicalTrials.gov 2026-10-18 04:37:23 | Détail |
| Oura Ring NCT07878975 · HRV Variation in Rheumatoid Arthritis | Maladie coronarienne | À vérifier | À vérifier | RECRUITING | The goal of this observational study is to determine the association betwe… À vérifier | ClinicalTrials.gov 2026-10-18 04:37:23 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4871
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Effects of continuous vs. intermittent transcutaneous electrical stim… Transcutaneous electrical nerve stimulation unit (TENS) · PMID 41866984 | Maladie rénale chronique | Traitement symptomatique | Publication | PubMed | Voir la publication source To compare the effects of two transcutaneous electrical stimulation (TES) patterns applied to the auricular branches of… | Cranio : the journal of craniomandibular practice 2026-11-08 04:38:07 | Source |
| Optimizing Percutaneous Tibial Nerve Stimulation Intensity for Overac… Transcutaneous electrical nerve stimulation unit (TENS) · PMID 42554545 | Maladie rénale chronique | Traitement symptomatique | Publication | PubMed | Voir la publication source Overactive bladder (OAB) is a significant global health issue. The standard percutaneous tibial nerve stimulation (PTNS… | Neuromodulation : journal of the International Neuromo… 2026-11-08 04:38:07 | Source |
| Transcutaneous auricular vagus nerve stimulation improves dysautonomi… Transcutaneous electrical nerve stimulation unit (TENS) · PMID 42802247 | Maladie rénale chronique | Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source Autonomic nervous system dysfunction is highly prevalent in hypermobile Ehlers-Danlos syndrome (hEDS) and contributes s… | Neurological sciences : official journal of the Italia… 2026-11-08 04:38:07 | Source |
| Factors associated with high-flow therapy failure in COVID-19-related… Non-Invasive Positive Pressure Ventilation · PMID 42888091 | Maladie rénale chronique | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source The optimal selection of non-invasive respiratory support for patients with COVID-19-related acute hypoxemic respirator… | Enfermedades infecciosas y microbiologia clinica (Engl… 2026-11-08 04:38:06 | Source |
| High-Flow Nasal Cannula in Adult Acute Care: Physiological Mechanisms… Non-Invasive Positive Pressure Ventilation · PMID 42942512 | Maladie rénale chronique | À vérifier | Publication | PubMed | Voir la publication source High-flow nasal cannula (HFNC) oxygen therapy is widely used in emergency, intensive care, perioperative, and procedura… | Medicina (Kaunas, Lithuania) 2026-11-08 04:38:06 | Source |
| Impact of respiratory support on time to achieve full oral feeding in… Non-Invasive Positive Pressure Ventilation · PMID 42871336 | Maladie rénale chronique | À vérifier | Publication | PubMed | Voir la publication source Very low birth weight infants often require respiratory support, which may delay full oral feeding. The independent rol… | Frontiers in pediatrics 2026-11-08 04:38:06 | Source |
| A comparative analysis of 3MAX aspiration versus 3 mm Trevo Retriever… Thromboaspiration catheter · PMID 31243066 | Accident vasculaire cérébral | À vérifier | Publication | PubMed | Voir la publication source Although aspiration and stent retriever thrombectomy perform similarly in proximal occlusions, no comparative series ar… | Journal of neurointerventional surgery 2026-11-08 04:38:02 | Source |
| Percutaneous Pulmonary Thrombectomy Beyond Acute Pulmonary Embolism:… Thromboaspiration catheter · PMID 38385241 | Accident vasculaire cérébral | Thérapie génique | Publication | PubMed | Voir la publication source Subacute massive pulmonary embolism is an uncommon manifestation of severe pulmonary embolism associated with poor prog… | Journal of endovascular therapy : an official journal… 2026-11-08 04:38:02 | Source |
| Simplified classification of cavernous internal carotid artery tortuo… Thromboaspiration catheter · PMID 35475775 | Hypertension artérielle · Accident vasculaire cérébral | Thérapie génique | Publication | PubMed | Voir la publication source Thromboaspiration catheters are increasingly used for the endovascular treatment of large vessel stroke (LVS), while to… | Neurological research 2026-11-08 04:38:02 | Source |
| Multifocal continuous theta burst stimulation in idiopathic generaliz… Continuous Theta Burst Stimulation (cTBS) · PMID 42731195 | Accident vasculaire cérébral | Traitement symptomatique | Publication | PubMed | Voir la publication source Idiopathic generalized epilepsy (IGE) is a disorder of the cortico-subcortical networks. Continuous theta burst stimula… | Clinical neurophysiology : official journal of the Int… 2026-11-08 04:38:00 | Source |
| Optimizing brain functional-structural architecture with cTBS to redu… Continuous Theta Burst Stimulation (cTBS) · PMID 42457860 | Accident vasculaire cérébral | À vérifier | Publication | PubMed | Voir la publication source Alcohol use disorder (AUD) is characterized by high relapse rates, necessitating novel interventions. Continuous theta-… | Molecular psychiatry 2026-11-08 04:38:00 | Source |
| Digital Outreach to Improve Statin Refills in Patients With Low Stati… Cordio System · PMID 42667613 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Statin nonadherence is a leading, addressable driver of preventable cardiovascular events. Although health systems rout… | JAMA 2026-11-08 04:37:54 | Source |
| Endovascular ablation of the right greater splanchnic nerve for the m… Right Greater Splanchnic Nerve (GSN) ablation · PMID 42257781 | Insuffisance cardiaque | Traitement symptomatique | Publication | PubMed | Voir la publication source Heart failure with preserved ejection fraction (HFpEF) remains difficult to manage because conventional therapies often… | The Egyptian heart journal : (EHJ) : official bulletin… 2026-11-08 04:37:54 | Source |
| Incidence, medical therapy, and outcomes in heart failure with improv… Cordio System · PMID 42702264 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source To assess the incidence of heart failure with improved ejection fraction (HFimpEF) across guideline definitions (ACC/AH… | American heart journal 2026-11-08 04:37:54 | Source |
| Relationship Between the Azygos Vein and the Greater Splanchnic Nerve… Right Greater Splanchnic Nerve (GSN) ablation · PMID 42249803 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Although ablation of the greater splanchnic nerve is now being used to treat some patients with heart failure, the anat… | Clinical anatomy (New York, N.Y.) 2026-11-08 04:37:54 | Source |
| Validation of the PREVENT-HF Risk Prediction Equation in US Veterans. Cordio System · PMID 42969140 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Résumé non disponible dans la base locale. | Circulation 2026-11-08 04:37:54 | Source |
| Changes in right ventricular-pulmonary artery coupling after transcat… Tricuspid Transcatheter Edge-to-Edge Repair (TEER) · PMID 42822601 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Right ventricular-pulmonary artery (RV-PA) coupling is an established marker of prognosis in mitral regurgitation (MR),… | International journal of cardiology 2026-11-08 04:37:47 | Source |
| Intraprocedural evaluation of residual mitral and tricuspid regurgita… Tricuspid Transcatheter Edge-to-Edge Repair (TEER) · PMID 42982241 | Maladie coronarienne | À vérifier | Publication | PubMed | Voir la publication source Transcatheter edge-to-edge repair (TEER) has emerged as an established therapeutic option for selected patients with se… | International journal of cardiology 2026-11-08 04:37:47 | Source |
| Tricuspid transcatheter edge-to-edge repair versus transcatheter tric… Tricuspid Transcatheter Edge-to-Edge Repair (TEER) · PMID 42989943 | Maladie coronarienne | À vérifier | Publication | PubMed | Voir la publication source Recent clinical studies of tricuspid transcatheter edge-to-edge repair (T-TEER) and transcatheter tricuspid valve repla… | Current opinion in cardiology 2026-11-08 04:37:47 | Source |
| Automated Production of Gene-Edited CAR-T Cells for People Living wit… RAPA-501 Autologous T stem cells · PMID 42847201 | Cancer | Thérapie cellulaire · Thérapie génique | Publication | PubMed | Voir la publication source Adoptive transfer of gene-modified autologous T cells, for example, expressing chimeric antigen receptors (CARs), is a… | Human gene therapy 2026-11-08 04:37:39 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||