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Toutes les maladies
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Périmètre
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10635 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 5743
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| NIRS-based cerebral oxygenation and blood pressure monitoring NCT07747701 · FACTOR — Ultra-early Identification of Futile Recanalization After Reperfusion T… | Accident vasculaire cérébral | À vérifier | Non applicable | RECRUITING | This multicenter, prospective, and interventional diagnostic accuracy stud… À vérifier | ClinicalTrials.gov 2026-10-18 04:37:41 | Détail |
| Tafolecimab NCT07341958 · INtensive liPid-lowering Therapy for Acute High-risk IntracRanial or Extracrania… | Accident vasculaire cérébral | À vérifier | Non applicable | NOT_YET_RECRUITING | The research team is conducting a randomized, double-blind, placebo-contro… À vérifier | ClinicalTrials.gov 2026-10-18 04:37:41 | Détail |
| Tocilizumab NCT07509645 · IRIS-3 — Efficacy and Safety of Interleukin-6 Receptor Inhibitor Combined With E… | Accident vasculaire cérébral | À vérifier | Phase 3 | RECRUITING | The purpose of this study is to investigate the safety, tolerability, phar… À vérifier | ClinicalTrials.gov 2026-10-18 04:37:41 | Détail |
| Vivistim System NCT05301140 · Vivistim Registry for Paired VNS Therapy (GRASP) | Accident vasculaire cérébral | À vérifier | À vérifier | RECRUITING | The purpose of the Vivistim Registry for Paired VNS Therapy (GRASP) is to… À vérifier | ClinicalTrials.gov 2026-10-18 04:37:41 | Détail |
| Zastaprazan NCT07730840 · Zastaprazan for the prEvention of Upper GI Bleeding in Ischemic Stroke | Accident vasculaire cérébral | Thérapie génique | Phase 3 | NOT_YET_RECRUITING | The goal of this clinical trial is to learn if zastaprazan can help preven… À vérifier | ClinicalTrials.gov 2026-10-18 04:37:41 | Détail |
| Zoom System NCT07491952 · ADAPT 2 0 — Continuous Dual Aspiration Technique With Zoom System for Stroke | Accident vasculaire cérébral | À vérifier | À vérifier | RECRUITING | This study is designed to evaluate the effectiveness, safety and clinical… À vérifier | ClinicalTrials.gov 2026-10-18 04:37:41 | Détail |
| BASIS technique NCT06881420 · BASIS Technique for Endovascular Therapy of Acute Large Vessel Occlusion Strokes… | Accident vasculaire cérébral | Traitement symptomatique | À vérifier | RECRUITING | This study will explore the safety and efficacy of BASIS technology in ICA… À vérifier | ClinicalTrials.gov 2026-10-18 04:37:40 | Détail |
| REGN7508 NCT07430956 · ROXI-INCLINE — Stroke and Systemic Embolism Prevention in Adult Participants Wit… | Accident vasculaire cérébral | À vérifier | Phase 3 | RECRUITING | This study is researching 2 different experimental drugs called REGN7508 a… À vérifier | ClinicalTrials.gov 2026-10-18 04:37:40 | Détail |
| Tenecteplase NCT07361302 · TENACITY — A Study to Test if Tenecteplase Helps People to Recover From an Acute… | Accident vasculaire cérébral | Ralentissement de la progression | Phase 3 | RECRUITING | This study is open to adults who had an acute stroke caused by a clot bloc… À vérifier | ClinicalTrials.gov 2026-10-18 04:37:40 | Détail |
| Tociliuzumab NCT07870681 · Infarct Growth After Intravenous Tocilizumab in Adults With Acute Ischemic Strok… | Accident vasculaire cérébral | Neuroprotection | Phase 2/3 | NOT_YET_RECRUITING | The goal of this phase II, placebo-controlled intervention study is to inv… À vérifier | ClinicalTrials.gov 2026-10-18 04:37:40 | Détail |
| anodal transcranial direct current stimulation (a-tDCS) NCT06681207 · Explore the Effects of Cortical Priming on Visuomotor Stepping Learning in Perso… | Accident vasculaire cérébral | À vérifier | Non applicable | RECRUITING | This research study aims to understand the relationship between brain stim… À vérifier | ClinicalTrials.gov 2026-10-18 04:37:38 | Détail |
| anodal transcranial direct current stimulation (a-tDCS) NCT06191549 · Brain Stimulation Enhance Post-stroke Walking Survivors and Healthy Adults | Accident vasculaire cérébral | À vérifier | Non applicable | RECRUITING | This research study aims to understand the relationship between brain stim… À vérifier | ClinicalTrials.gov 2026-10-18 04:37:38 | Détail |
| hyaluronidase plus saline NCT06718413 · Myofascial Dysfunction in Post Stroke Shoulder Pain | Accident vasculaire cérébral | Traitement symptomatique | Phase 2 | RECRUITING | Shoulder pain is extremely common after stroke and occurs in 30-70% of pat… À vérifier | ClinicalTrials.gov 2026-10-18 04:37:38 | Détail |
| Mechanical thrombectomy NCT06758609 · CHILL-ART — To Assess the Effectiveness and Safety of Catheter-based Focal Intra… | Accident vasculaire cérébral | À vérifier | Non applicable | COMPLETED | A multicenter, prospective, open-label, blinded-endpoint, randomized contr… À vérifier | ClinicalTrials.gov 2026-10-18 04:37:38 | Détail |
| Pelacarsen (TQJ230) NCT07517263 · An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to E… | Accident vasculaire cérébral | À vérifier | Phase 3 | ACTIVE_NOT_RECRUITING | This open-label extension study provides post-trial access to pelacarsen (… À vérifier | ClinicalTrials.gov 2026-10-18 04:37:38 | Détail |
| Phenylephrine NCT04218773 · Blood PREssure Augmentation in Large-vessel Occlusion Stroke Study | Accident vasculaire cérébral | Ralentissement de la progression | Phase 1 | TERMINATED | An open label, prospective, single center, pilot trial to assess feasibili… À vérifier | ClinicalTrials.gov 2026-10-18 04:37:38 | Détail |
| WATCHMAN FLX LAAC Device NCT04394546 · CHAMPION-AF Clinical Trial | Accident vasculaire cérébral | Thérapie génique | Non applicable | ACTIVE_NOT_RECRUITING | The primary objective of this study is to determine if left atrial appenda… À vérifier | ClinicalTrials.gov 2026-10-18 04:37:38 | Détail |
| Acu-TENS NCT05623137 · Acu-TENS to Improve the Sleep Quality in People With Stroke | Accident vasculaire cérébral | À vérifier | Non applicable | COMPLETED | Post-stroke sleep disorder and motor/cognitive dysfunction are common comp… À vérifier | ClinicalTrials.gov 2026-10-18 04:37:37 | Détail |
| AFSW Guided DOAC NCT05836987 · REACT-AF — The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring… | Accident vasculaire cérébral | À vérifier | Phase 3 | RECRUITING | REACT-AF is a multicenter prospective, randomized, open-label, blinded end… À vérifier | ClinicalTrials.gov 2026-10-18 04:37:37 | Détail |
| Apixaban NCT07237308 · BEACON-AA: Apixaban With or Without Clopidogrel in Stroke Patients With Atrial F… | Accident vasculaire cérébral | Traitement symptomatique | Phase 4 | RECRUITING | This trial aims to compare the safety and efficacy of apixaban alone versu… À vérifier | ClinicalTrials.gov 2026-10-18 04:37:37 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4871
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Effects of continuous vs. intermittent transcutaneous electrical stim… Transcutaneous electrical nerve stimulation unit (TENS) · PMID 41866984 | Maladie rénale chronique | Traitement symptomatique | Publication | PubMed | Voir la publication source To compare the effects of two transcutaneous electrical stimulation (TES) patterns applied to the auricular branches of… | Cranio : the journal of craniomandibular practice 2026-11-08 04:38:07 | Source |
| Optimizing Percutaneous Tibial Nerve Stimulation Intensity for Overac… Transcutaneous electrical nerve stimulation unit (TENS) · PMID 42554545 | Maladie rénale chronique | Traitement symptomatique | Publication | PubMed | Voir la publication source Overactive bladder (OAB) is a significant global health issue. The standard percutaneous tibial nerve stimulation (PTNS… | Neuromodulation : journal of the International Neuromo… 2026-11-08 04:38:07 | Source |
| Transcutaneous auricular vagus nerve stimulation improves dysautonomi… Transcutaneous electrical nerve stimulation unit (TENS) · PMID 42802247 | Maladie rénale chronique | Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source Autonomic nervous system dysfunction is highly prevalent in hypermobile Ehlers-Danlos syndrome (hEDS) and contributes s… | Neurological sciences : official journal of the Italia… 2026-11-08 04:38:07 | Source |
| Factors associated with high-flow therapy failure in COVID-19-related… Non-Invasive Positive Pressure Ventilation · PMID 42888091 | Maladie rénale chronique | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source The optimal selection of non-invasive respiratory support for patients with COVID-19-related acute hypoxemic respirator… | Enfermedades infecciosas y microbiologia clinica (Engl… 2026-11-08 04:38:06 | Source |
| High-Flow Nasal Cannula in Adult Acute Care: Physiological Mechanisms… Non-Invasive Positive Pressure Ventilation · PMID 42942512 | Maladie rénale chronique | À vérifier | Publication | PubMed | Voir la publication source High-flow nasal cannula (HFNC) oxygen therapy is widely used in emergency, intensive care, perioperative, and procedura… | Medicina (Kaunas, Lithuania) 2026-11-08 04:38:06 | Source |
| Impact of respiratory support on time to achieve full oral feeding in… Non-Invasive Positive Pressure Ventilation · PMID 42871336 | Maladie rénale chronique | À vérifier | Publication | PubMed | Voir la publication source Very low birth weight infants often require respiratory support, which may delay full oral feeding. The independent rol… | Frontiers in pediatrics 2026-11-08 04:38:06 | Source |
| A comparative analysis of 3MAX aspiration versus 3 mm Trevo Retriever… Thromboaspiration catheter · PMID 31243066 | Accident vasculaire cérébral | À vérifier | Publication | PubMed | Voir la publication source Although aspiration and stent retriever thrombectomy perform similarly in proximal occlusions, no comparative series ar… | Journal of neurointerventional surgery 2026-11-08 04:38:02 | Source |
| Percutaneous Pulmonary Thrombectomy Beyond Acute Pulmonary Embolism:… Thromboaspiration catheter · PMID 38385241 | Accident vasculaire cérébral | Thérapie génique | Publication | PubMed | Voir la publication source Subacute massive pulmonary embolism is an uncommon manifestation of severe pulmonary embolism associated with poor prog… | Journal of endovascular therapy : an official journal… 2026-11-08 04:38:02 | Source |
| Simplified classification of cavernous internal carotid artery tortuo… Thromboaspiration catheter · PMID 35475775 | Hypertension artérielle · Accident vasculaire cérébral | Thérapie génique | Publication | PubMed | Voir la publication source Thromboaspiration catheters are increasingly used for the endovascular treatment of large vessel stroke (LVS), while to… | Neurological research 2026-11-08 04:38:02 | Source |
| Multifocal continuous theta burst stimulation in idiopathic generaliz… Continuous Theta Burst Stimulation (cTBS) · PMID 42731195 | Accident vasculaire cérébral | Traitement symptomatique | Publication | PubMed | Voir la publication source Idiopathic generalized epilepsy (IGE) is a disorder of the cortico-subcortical networks. Continuous theta burst stimula… | Clinical neurophysiology : official journal of the Int… 2026-11-08 04:38:00 | Source |
| Optimizing brain functional-structural architecture with cTBS to redu… Continuous Theta Burst Stimulation (cTBS) · PMID 42457860 | Accident vasculaire cérébral | À vérifier | Publication | PubMed | Voir la publication source Alcohol use disorder (AUD) is characterized by high relapse rates, necessitating novel interventions. Continuous theta-… | Molecular psychiatry 2026-11-08 04:38:00 | Source |
| Digital Outreach to Improve Statin Refills in Patients With Low Stati… Cordio System · PMID 42667613 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Statin nonadherence is a leading, addressable driver of preventable cardiovascular events. Although health systems rout… | JAMA 2026-11-08 04:37:54 | Source |
| Endovascular ablation of the right greater splanchnic nerve for the m… Right Greater Splanchnic Nerve (GSN) ablation · PMID 42257781 | Insuffisance cardiaque | Traitement symptomatique | Publication | PubMed | Voir la publication source Heart failure with preserved ejection fraction (HFpEF) remains difficult to manage because conventional therapies often… | The Egyptian heart journal : (EHJ) : official bulletin… 2026-11-08 04:37:54 | Source |
| Incidence, medical therapy, and outcomes in heart failure with improv… Cordio System · PMID 42702264 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source To assess the incidence of heart failure with improved ejection fraction (HFimpEF) across guideline definitions (ACC/AH… | American heart journal 2026-11-08 04:37:54 | Source |
| Relationship Between the Azygos Vein and the Greater Splanchnic Nerve… Right Greater Splanchnic Nerve (GSN) ablation · PMID 42249803 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Although ablation of the greater splanchnic nerve is now being used to treat some patients with heart failure, the anat… | Clinical anatomy (New York, N.Y.) 2026-11-08 04:37:54 | Source |
| Validation of the PREVENT-HF Risk Prediction Equation in US Veterans. Cordio System · PMID 42969140 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Résumé non disponible dans la base locale. | Circulation 2026-11-08 04:37:54 | Source |
| Changes in right ventricular-pulmonary artery coupling after transcat… Tricuspid Transcatheter Edge-to-Edge Repair (TEER) · PMID 42822601 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Right ventricular-pulmonary artery (RV-PA) coupling is an established marker of prognosis in mitral regurgitation (MR),… | International journal of cardiology 2026-11-08 04:37:47 | Source |
| Intraprocedural evaluation of residual mitral and tricuspid regurgita… Tricuspid Transcatheter Edge-to-Edge Repair (TEER) · PMID 42982241 | Maladie coronarienne | À vérifier | Publication | PubMed | Voir la publication source Transcatheter edge-to-edge repair (TEER) has emerged as an established therapeutic option for selected patients with se… | International journal of cardiology 2026-11-08 04:37:47 | Source |
| Tricuspid transcatheter edge-to-edge repair versus transcatheter tric… Tricuspid Transcatheter Edge-to-Edge Repair (TEER) · PMID 42989943 | Maladie coronarienne | À vérifier | Publication | PubMed | Voir la publication source Recent clinical studies of tricuspid transcatheter edge-to-edge repair (T-TEER) and transcatheter tricuspid valve repla… | Current opinion in cardiology 2026-11-08 04:37:47 | Source |
| Automated Production of Gene-Edited CAR-T Cells for People Living wit… RAPA-501 Autologous T stem cells · PMID 42847201 | Cancer | Thérapie cellulaire · Thérapie génique | Publication | PubMed | Voir la publication source Adoptive transfer of gene-modified autologous T cells, for example, expressing chimeric antigen receptors (CARs), is a… | Human gene therapy 2026-11-08 04:37:39 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||