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Synchronisé depuis ClinicalTrials.gov — NCT05152147

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47
MoléculeIndication / populationPhaseNCTTitreStatut
INBRX-106 - Hexavalent OX40 agonist antibody Cancer Phase 1/2 NCT04198766 Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist) RECRUITING
Carisbamate Épilepsie Phase 3 NCT05219617 Investigate Efficacy and Safety of Carisbamate as Adjunctive Treatment for Seizures Associated With LGS in Children and Adults RECRUITING
Maridebart cafraglutide Insuffisance cardiaque Phase 3 NCT07037459 MARITIME-HF — Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity RECRUITING
Selatogrel Maladie coronarienne Phase 3 NCT04957719 SOS-AMI — Selatogrel Outcome Study in Suspected Acute Myocardial Infarction ENROLLING_BY_INVITATION
Adagrasib Cancer Phase 2/3 NCT04613596 Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7 RECRUITING
FARAPULSE™ PFA system and WATCHMAN LAAC Delivery Systems Maladie coronarienne À vérifier NCT06686485 OPTION-A — Concomitant Left Atrial Appendage Closure and Pulsed Field Ablation-Asia ACTIVE_NOT_RECRUITING
FARAPULSE™ Pulsed Field Ablation System Maladie coronarienne Non applicable NCT06735534 ReMATCH — Repeat Ablation of Persistent Atrial Fibrillation, Including Mitral Isthmus Catheter Ablation, With the FARAPULSE Pulsed Field Ablation System ACTIVE_NOT_RECRUITING
Nivolumab Cancer Phase 3 NCT06561386 RELATIVITY1093 — A Study to Compare the Efficacy of Nivolumab and Relatlimab Plus Chemotherapy vs Pembrolizumab Plus Chemotherapy for Stage IV/Recurrent Non-squamous Non-small Cell Lung Cancer With PD-L1 Expression ≥ 1% RECRUITING
BI 690517 Maladie rénale chronique Phase 3 NCT06531824 EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin) ACTIVE_NOT_RECRUITING
Finerenone (Kerendia, BAY94-8862) Maladie rénale chronique Phase 3 NCT05196035 FIONA — A Study to Learn More About How Well the Study Treatment Finerenone Works, How Safe it is, How it Moves Into, Through, and Out of the Body, and the Effects it Has on the Body When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker in Children With Chronic Kidney Disease and Proteinuria ACTIVE_NOT_RECRUITING
Tenecteplase Accident vasculaire cérébral Phase 3 NCT07361302 TENACITY — A Study to Test if Tenecteplase Helps People to Recover From an Acute Stroke When Given More Than 4.5 Hours After the Person Was Last Seen Well RECRUITING
Vicadrostat Insuffisance cardiaque Phase 3 NCT06424288 A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure RECRUITING
Vicadrostat Insuffisance cardiaque Phase 3 NCT06935370 A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart RECRUITING
Percutaneous coronary intervention of coronary chronic total occlusion Maladie coronarienne À vérifier NCT06917378 TRIO CTO (Taiwan Research Initiative on Coronary Total Occlusion) RECRUITING
Exablate 4000 Transcranial MRgfUS System Épilepsie Non applicable NCT06292494 Focused Ultrasound for Drug-resistant Epilepsy RECRUITING
KarXT Alzheimer Phase 3 NCT06937229 A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer's Disease (ADAGIO-3) RECRUITING
Iza-bren Cancer Phase 2/3 NCT07100080 Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01) RECRUITING
PF-08634404 Cancer Phase 2 NCT07476287 Symbiotic-Lung-14: A Study to Learn About the Study Medicine Called PF08634404 in Combination With Chemotherapy in Adult Participants With Transformed Small Cell Lung Cancer RECRUITING
Pasritamig Cancer Phase 3 NCT07164443 KLK2-comPAS — A Study of Pasritamig With or Without JNJ-87189401 Versus Placebo for Late Line Metastatic Castration-resistant Prostate Cancer (mCRPC) RECRUITING
Zanidatamab Parkinson Phase 3 NCT05152147 HERIZON-GEA-01 — A Study of Zanidatamab in Combination With Chemotherapy Plus or Minus Tislelizumab in Patients With HER2-positive Advanced or Metastatic Gastric and Esophageal Cancers ACTIVE_NOT_RECRUITING
Sotorasib Cancer Phase 3 NCT05920356 A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202) RECRUITING
Trontinemab Alzheimer Phase 3 NCT07717411 PrevenTRON — A Study of Trontinemab in Cognitively Unimpaired Individuals at Risk for Progression to Symptomatic Alzheimer's Disease RECRUITING
Domvanalimab Cancer Phase 2 NCT06727565 VELOCITY-HNSCC — Study of Novel Treatment Combination Therapies in Participants With Head and Neck Squamous Cell Carcinoma Regardless of PD-L1 Expression Status; Substudy-01 ACTIVE_NOT_RECRUITING
Inavolisib Cancer Phase 3 NCT06790693 INAVO123 — A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer RECRUITING
Nerandomilast Myopathies Phase 3 NCT07789015 VERANDA™-IIM — A Study to Understand How Nerandomilast Works in People With Active Idiopathic Inflammatory Myopathies NOT_YET_RECRUITING
M5049 low dose Lupus Phase 2 NCT05540327 The Willow LTE Study With M5049 in Participants With SCLE, DLE and/or SLE (WILLOW LTE) ACTIVE_NOT_RECRUITING
PF-06821497 Cancer Phase 3 NCT06629779 A Study to Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic Castration-resistant Prostate Cancer. RECRUITING
Vicadrostat Hypertension Phase 3 NCT07064473 EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease RECRUITING
Precemtabart tocentecan Cancer Phase 3 NCT07549412 A Study of Precemtabart Tocentecan With or Without Bevacizumab Compared to Trifluridine/Tipiracil Plus Bevacizumab in Participants With Previously Treated Metastatic Colorectal Cancer (PROCEADE-CRC-03) RECRUITING
Cenerimod Lupus Phase 3 NCT06475742 OPUS OLE — Long-term Safety and Tolerability of Cenerimod in Adults With Systemic Lupus Erythematosus ENROLLING_BY_INVITATION
Cenerimod Lupus Phase 3 NCT05648500 OPUS-1 — A Research Study to Evaluate the Effects of a New Oral Medicine Called Cenerimod in Adults With Systemic Lupus Erythematosus ACTIVE_NOT_RECRUITING
Acoramidis Alzheimer Phase 3 NCT06563895 Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant RECRUITING
Donanemab Alzheimer Phase 2 NCT07589595 A Study of Donanemab (LY3002813) in Participants With Early Cognitive Decline (TRAILBLAZER-ALZ 7) RECRUITING
Trontinemab Alzheimer Phase 3 NCT07169578 TRONTIER 1 — A Study of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease ACTIVE_NOT_RECRUITING
Prasinezumab Parkinson Phase 3 NCT07174310 PARAISO — A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease RECRUITING
ALN-SOD Sclérose latérale amyotrophique Phase 1/2 NCT06351592 GOALS — First in Human (FIH) Study of ALN-SOD in Adult Participants With Amyotrophic Lateral Sclerosis Associated With Mutation in the SOD1 Gene (SOD1-ALS) RECRUITING
Nipocalimab Myasthénie Phase 3 NCT04951622 A Study of Nipocalimab Administered to Adults With Generalized Myasthenia Gravis RECRUITING
Cladribine Low Dose Myasthénie Phase 3 NCT06463587 Efficacy and Safety of a New Formulation of Oral Cladribine Compared With Placebo in Participants With Generalized Myasthenia Gravis (MyClad) RECRUITING
PF-06939926 Myopathies Phase 3 NCT04281485 Study to Evaluate the Safety and Efficacy of PF-06939926 for the Treatment of Duchenne Muscular Dystrophy ACTIVE_NOT_RECRUITING
SRP-1003 IV Infusion Myopathies Phase 1/2 NCT06138743 Study of SRP-1003 in Participants With Type 1 Myotonic Dystrophy ENROLLING_BY_INVITATION
Nipocalimab Lupus Phase 3 NCT07438496 GARDENIA-SLE — A Study of Nipocalimab in Adults With Moderate to Severe Systemic Lupus Erythematosus RECRUITING
BIIB059 (litifilimab) Lupus Phase 3 NCT06044337 AMETHYST LTE — A Long-Term Extension Study to Learn More About the Safety of Litifilimab (BIIB059) Injections and Whether They Can Improve Symptoms of Adult Participants Who Have Active Cutaneous Lupus Erythematosus ENROLLING_BY_INVITATION
BI 3000202 Lupus Phase 2 NCT07409181 A Study to Test Whether Different Doses of BI 3000202 Help People With Systemic Lupus Erythematosus (SLE) RECRUITING
Vonsetamig Lupus Phase 1 NCT06975787 Dose Escalation Study With Bispecific Antibodies in Adult Participants With Lupus Nephritis RECRUITING
Litifilimab Lupus Phase 2/3 NCT05531565 AMETHYST — A 2-Part Study to Learn Whether Litifilimab (BIIB059) Injections Can Improve Symptoms of Adult Participants Who Have Active Cutaneous Lupus Erythematosus ACTIVE_NOT_RECRUITING
Xanomeline/Trospium Chloride Capsule Alzheimer Phase 3 NCT07011732 A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-1) RECRUITING
uAOBP Hypertension NA NCT03578848 GYMNs — Guiding Hypertension Management Using Different Blood Pressure Monitoring Strategies UNKNOWN