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Synchronisé depuis ClinicalTrials.gov — NCT05152147

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38
MoléculeIndication / populationPhaseNCTTitreStatut
Ipatasertib Cancer Phase 3 NCT05862285 UmbrellaMAX — A Rollover Study for Participants Previously Enrolled in a Genentech and/or F. Hoffman-La Roche Sponsored Study RECRUITING
INBRX-106 - Hexavalent OX40 agonist antibody Cancer Phase 1/2 NCT04198766 Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist) RECRUITING
Selatogrel Maladie coronarienne Phase 3 NCT04957719 SOS-AMI — Selatogrel Outcome Study in Suspected Acute Myocardial Infarction ENROLLING_BY_INVITATION
Adagrasib Cancer Phase 2/3 NCT04613596 Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7 RECRUITING
BMS-986504 Cancer Phase 2/3 NCT07063745 MountainTAP-29 — A Study to Compare the Combination of Navlimetostat (BMS-986504) With Pembrolizumab and Chemotherapy Versus Placebo Plus Pembrolizumab and Chemotherapy in First-line Metastatic Non-small Cell Lung Cancer Participants With Homozygous MTAP Deletion RECRUITING
Nivolumab Cancer Phase 3 NCT06561386 RELATIVITY1093 — A Study to Compare the Efficacy of Nivolumab and Relatlimab Plus Chemotherapy vs Pembrolizumab Plus Chemotherapy for Stage IV/Recurrent Non-squamous Non-small Cell Lung Cancer With PD-L1 Expression ≥ 1% RECRUITING
Pumitamig Cancer Phase 1/2 NCT07293351 A Study to Evaluate the Safety, Tolerability, and Efficacy of Pumitamig Alone or in Combination With Other Agents in Participants With Advanced Renal Cell Carcinoma (RCC) (ROSETTA RCC-208) RECRUITING
Zastaprazan Accident vasculaire cérébral Phase 3 NCT07730840 Zastaprazan for the prEvention of Upper GI Bleeding in Ischemic Stroke NOT_YET_RECRUITING
Epcoritamab SEP Phase 2 NCT05660967 EPCORE DLBCL-3 — Subcutaneous Epcoritamab With or Without Lenalidomide as First Line Therapy for Diffuse Large B-Cell Lymphoma TERMINATED
Elacestrant Cancer Phase 1/2 NCT05386108 ELECTRA — Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer RECRUITING
KITE-363 Lupus Phase 1 NCT07038447 A Study of KITE-363 in Participants With Refractory Autoimmune Diseases ENROLLING_BY_INVITATION
Pasritamig Cancer Phase 3 NCT07164443 KLK2-comPAS — A Study of Pasritamig With or Without JNJ-87189401 Versus Placebo for Late Line Metastatic Castration-resistant Prostate Cancer (mCRPC) RECRUITING
Odronextamab Cancer Phase 3 NCT06091865 OLYMPIA-3 — A Study to Compare How Well Odronextamab Combined With Chemotherapy Works and How Safe it is Against Rituximab Combined With Chemotherapy, in Adult Patients With Previously Untreated Diffuse Large B-cell Lymphoma RECRUITING
Zanidatamab Parkinson Phase 3 NCT05152147 HERIZON-GEA-01 — A Study of Zanidatamab in Combination With Chemotherapy Plus or Minus Tislelizumab in Patients With HER2-positive Advanced or Metastatic Gastric and Esophageal Cancers ACTIVE_NOT_RECRUITING
cemacabtagene ansegedleucel SEP Phase 2 NCT06500273 ALPHA3 — Consolidation of First-Line MRD+ Remission With Cema-cel in Patients With LBCL RECRUITING
Giredestrant Cancer Phase 3 NCT06065748 A Study to Evaluate Efficacy and Safety of Giredestrant Compared With Fulvestrant (Plus a CDK4/6 Inhibitor), in Participants With ER-Positive, HER2-Negative Advanced Breast Cancer Resistant to Adjuvant Endocrine Therapy (pionERA Breast Cancer) ACTIVE_NOT_RECRUITING
Zanidatamab Cancer Phase 3 NCT06282575 Efficacy and Safety of Zanidatamab With Standard-of-care Therapy Against Standard-of-care Therapy for Advanced HER2-positive Biliary Tract Cancer RECRUITING
Sotorasib Cancer Phase 3 NCT05920356 A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202) RECRUITING
Obinutuzumab Cancer Phase 3 NCT06084936 GLOBRYTE — A Study to Evaluate Glofitamab as a Single Agent vs. Investigator's Choice in Participants With Relapsed/Refractory Mantle Cell Lymphoma RECRUITING
Inavolisib Cancer Phase 3 NCT06790693 INAVO123 — A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer RECRUITING
Amivantamab Cancer Phase 3 NCT04538664 PAPILLON — A Study of Combination Amivantamab and Carboplatin-Pemetrexed Therapy, Compared With Carboplatin-Pemetrexed, in Participants With Advanced or Metastatic Non-Small Cell Lung Cancer Characterized by Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertions ACTIVE_NOT_RECRUITING
Xanomeline/Trospium Chloride Capsule Alzheimer Phase 3 NCT07011745 A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease RECRUITING
Oxaliplatin, 5FU, leucovorin Cancer Phase 2 NCT07062536 mFOLFOX/mFOLFIRI vs. mFOLFOX in Advanced or Recurrent Biliary Tract Cancer Second-line RECRUITING
PF-06821497 Cancer Phase 3 NCT06629779 A Study to Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic Castration-resistant Prostate Cancer. RECRUITING
Vicadrostat Hypertension Phase 3 NCT07064473 EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease RECRUITING
Obinutuzumab Cancer Phase 2 NCT06806033 A Study to Evaluate the Optimization of the Cytokine Release Syndrome Profile for Glofitamab in Combination With Gemcitabine Plus Oxaliplatin in Participants With Relapsed/Refractory Aggressive B-Cell Non-Hodgkin's Lymphoma RECRUITING
DKF-MA102 Cancer Phase 3 NCT06490328 Efficacy and Safety of DKF-MA102 in Patients With Prostate Cancer COMPLETED
Precemtabart tocentecan Cancer Phase 3 NCT07549412 A Study of Precemtabart Tocentecan With or Without Bevacizumab Compared to Trifluridine/Tipiracil Plus Bevacizumab in Participants With Previously Treated Metastatic Colorectal Cancer (PROCEADE-CRC-03) RECRUITING
HyperQure Renal Denervation System Hypertension Non applicable NCT06216808 A First-in-human Study of HyperQureTM", Laparoscopic Renal Denervation Therapy in Patient With Resistant Hypertension ACTIVE_NOT_RECRUITING
Trontinemab Alzheimer Phase 3 NCT07170150 TRONTIER 2 — A Clinical Trial of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease ACTIVE_NOT_RECRUITING
Prasinezumab Parkinson Phase 3 NCT07174310 PARAISO — A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease RECRUITING
Cladribine Low Dose Myasthénie Phase 3 NCT06463587 Efficacy and Safety of a New Formulation of Oral Cladribine Compared With Placebo in Participants With Generalized Myasthenia Gravis (MyClad) RECRUITING
Nipocalimab Lupus Phase 3 NCT07438496 GARDENIA-SLE — A Study of Nipocalimab in Adults With Moderate to Severe Systemic Lupus Erythematosus RECRUITING
RAP-219 Épilepsie Phase 3 NCT07563881 FOCUS 1 — Study Evaluating the Efficacy and Safety of RAP-219 in Adult Participants With Focal Seizures FOCUS-1 RECRUITING
Irinotecan Cancer Phase 1 NCT00874328 A Study of TS-1 Plus Irinotecan and Cisplatin (IP) for Patients With Stage IIIB/IV Non Small Cell Lung Cancer (NSCLC) UNKNOWN
Pembrolizumab Parkinson Phase 3 NCT03358472 Pembrolizumab Plus Epacadostat, Pembrolizumab Monotherapy, and the EXTREME Regimen in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (KEYNOTE-669/ECHO-304) COMPLETED
Sacituzumab govitecan-hziy Cancer Phase 3 NCT06486441 Study of Sacituzumab Govitecan Versus Treatment of Physician's Choice in Participants With Endometrial Cancer After Platinum-Based Chemotherapy and Immunotherapy (ASCENT-GYN-01/GOG-3104/ENGOT-en26) ACTIVE_NOT_RECRUITING
Donepezil Alzheimer Phase 1 NCT02178124 A Phase I Clinical Study, Randomized, Single-blind, Placebo-controlled, Multiple Doses, Dose Escalation Study of the Safety, Tolerability and Pharmacokinetics of Donepezil Patch in Healthy Male Subjects. COMPLETED