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Synchronisé depuis ClinicalTrials.gov — NCT06091865

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51
MoléculeIndication / populationPhaseNCTTitreStatut
Ipatasertib Cancer Phase 3 NCT05862285 UmbrellaMAX — A Rollover Study for Participants Previously Enrolled in a Genentech and/or F. Hoffman-La Roche Sponsored Study RECRUITING
Carisbamate Épilepsie Phase 3 NCT05219617 Investigate Efficacy and Safety of Carisbamate as Adjunctive Treatment for Seizures Associated With LGS in Children and Adults RECRUITING
Survodutide Maladie rénale chronique Phase 3 NCT06077864 A Study to Test the Effect of Survodutide (BI 456906) on Cardiovascular Safety in People With Overweight or Obesity (SYNCHRONIZE™ - CVOT) COMPLETED
Maridebart cafraglutide Insuffisance cardiaque Phase 3 NCT07037459 MARITIME-HF — Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity RECRUITING
Selatogrel Maladie coronarienne Phase 3 NCT04957719 SOS-AMI — Selatogrel Outcome Study in Suspected Acute Myocardial Infarction ENROLLING_BY_INVITATION
Adagrasib Cancer Phase 2/3 NCT04613596 Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7 RECRUITING
FARAPULSE™ PFA system and WATCHMAN LAAC Delivery Systems Maladie coronarienne À vérifier NCT06686485 OPTION-A — Concomitant Left Atrial Appendage Closure and Pulsed Field Ablation-Asia ACTIVE_NOT_RECRUITING
FARAPULSE™ Pulsed Field Ablation System Maladie coronarienne Non applicable NCT06735534 ReMATCH — Repeat Ablation of Persistent Atrial Fibrillation, Including Mitral Isthmus Catheter Ablation, With the FARAPULSE Pulsed Field Ablation System ACTIVE_NOT_RECRUITING
BMS-986504 Cancer Phase 2/3 NCT07063745 MountainTAP-29 — A Study to Compare the Combination of Navlimetostat (BMS-986504) With Pembrolizumab and Chemotherapy Versus Placebo Plus Pembrolizumab and Chemotherapy in First-line Metastatic Non-small Cell Lung Cancer Participants With Homozygous MTAP Deletion RECRUITING
Nivolumab Cancer Phase 3 NCT06561386 RELATIVITY1093 — A Study to Compare the Efficacy of Nivolumab and Relatlimab Plus Chemotherapy vs Pembrolizumab Plus Chemotherapy for Stage IV/Recurrent Non-squamous Non-small Cell Lung Cancer With PD-L1 Expression ≥ 1% RECRUITING
Finerenone (Kerendia, BAY94-8862) Maladie rénale chronique Phase 3 NCT05196035 FIONA — A Study to Learn More About How Well the Study Treatment Finerenone Works, How Safe it is, How it Moves Into, Through, and Out of the Body, and the Effects it Has on the Body When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker in Children With Chronic Kidney Disease and Proteinuria ACTIVE_NOT_RECRUITING
Symplicity Spyral™ multi-electrode renal denervation system Maladie rénale chronique Non applicable NCT07115953 Streamlined Denervation With spYral For an Optimized Treatment (SPYRAL SWYFT) in Subjects With Uncontrolled Hypertension RECRUITING
Tenecteplase Accident vasculaire cérébral Phase 3 NCT07361302 TENACITY — A Study to Test if Tenecteplase Helps People to Recover From an Acute Stroke When Given More Than 4.5 Hours After the Person Was Last Seen Well RECRUITING
peripheral magnetic stimulation Accident vasculaire cérébral Non applicable NCT05112094 Peripheral Magnetic Stimulation to Treat Patient With Post-stroke Shoulder-hand Syndrome COMPLETED
Vicadrostat Insuffisance cardiaque Phase 3 NCT06424288 A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure RECRUITING
Finerenone (Kerendia, BAY94-8862) Insuffisance cardiaque Phase 3 NCT07192952 FIORELLO — A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction RECRUITING
Finerenone (Kerendia, BAY94-8862) Insuffisance cardiaque Phase 3 NCT07188805 FIORE — A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction RECRUITING
Percutaneous coronary intervention of coronary chronic total occlusion Maladie coronarienne À vérifier NCT06917378 TRIO CTO (Taiwan Research Initiative on Coronary Total Occlusion) RECRUITING
Iza-bren Cancer Phase 2/3 NCT07100080 Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01) RECRUITING
PF-08634404 Cancer Phase 2 NCT07476287 Symbiotic-Lung-14: A Study to Learn About the Study Medicine Called PF08634404 in Combination With Chemotherapy in Adult Participants With Transformed Small Cell Lung Cancer RECRUITING
Melatonin Épilepsie Phase 2/3 NCT05439876 Getting SMART for Pediatric Epilepsy COMPLETED
Pasritamig Cancer Phase 3 NCT07164443 KLK2-comPAS — A Study of Pasritamig With or Without JNJ-87189401 Versus Placebo for Late Line Metastatic Castration-resistant Prostate Cancer (mCRPC) RECRUITING
Odronextamab Cancer Phase 3 NCT06091865 OLYMPIA-3 — A Study to Compare How Well Odronextamab Combined With Chemotherapy Works and How Safe it is Against Rituximab Combined With Chemotherapy, in Adult Patients With Previously Untreated Diffuse Large B-cell Lymphoma RECRUITING
Histotripsie — HistoSonics Edison System Cancer Non applicable NCT07207343 Symptomatic Abdominal Tumors Are Unsuitable for Surgical Resection, High-intensity Focused Ultrasound (HIFU) Treatment Will be Applied to the Tumors. Postoperatively, Continuous Evaluation and Analysis of the Ablation Effect Will be Performed Using CT or MRI Imaging. ACTIVE_NOT_RECRUITING
Sotorasib Cancer Phase 3 NCT05920356 A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202) RECRUITING
Trontinemab Alzheimer Phase 3 NCT07717411 PrevenTRON — A Study of Trontinemab in Cognitively Unimpaired Individuals at Risk for Progression to Symptomatic Alzheimer's Disease RECRUITING
Ozanimod SEP Phase 3 NCT06408259 Study to Evaluate the Effectiveness and Safety of Ozanimod Compared to Fingolimod in Children and Adolescents With Relapsing Remitting Multiple Sclerosis RECRUITING
Amivantamab Cancer Phase 3 NCT04538664 PAPILLON — A Study of Combination Amivantamab and Carboplatin-Pemetrexed Therapy, Compared With Carboplatin-Pemetrexed, in Participants With Advanced or Metastatic Non-Small Cell Lung Cancer Characterized by Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertions ACTIVE_NOT_RECRUITING
ACP-204 Alzheimer Phase 2/3 NCT06159673 ACP-204 in Adults With Alzheimer's Disease Psychosis RECRUITING
PF-06821497 Cancer Phase 3 NCT06629779 A Study to Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic Castration-resistant Prostate Cancer. RECRUITING
Vicadrostat Hypertension Phase 3 NCT07064473 EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease RECRUITING
SMART-2 — Sleep, Music, And Research Trial 2.0 Épilepsie Non applicable NCT07696442 SMART-2 — Sleep, Music, And Research Trial 2.0 NOT_YET_RECRUITING
Adagrasib Cancer Phase 3 NCT06875310 A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4) RECRUITING
Cenerimod Lupus Phase 3 NCT06475742 OPUS OLE — Long-term Safety and Tolerability of Cenerimod in Adults With Systemic Lupus Erythematosus ENROLLING_BY_INVITATION
Cenerimod Lupus Phase 3 NCT05648500 OPUS-1 — A Research Study to Evaluate the Effects of a New Oral Medicine Called Cenerimod in Adults With Systemic Lupus Erythematosus ACTIVE_NOT_RECRUITING
Acoramidis Alzheimer Phase 3 NCT06563895 Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant RECRUITING
Donanemab Alzheimer Phase 2 NCT07589595 A Study of Donanemab (LY3002813) in Participants With Early Cognitive Decline (TRAILBLAZER-ALZ 7) RECRUITING
Trontinemab Alzheimer Phase 3 NCT07169578 TRONTIER 1 — A Study of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease ACTIVE_NOT_RECRUITING
Prasinezumab Parkinson Phase 3 NCT07174310 PARAISO — A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease RECRUITING
plasmapheresis Sclérose latérale amyotrophique Non applicable NCT05562960 PALATIN — Plasmapheresis in Amyotrophic Lateral Sclerosis With Autoantibody Against NRIP COMPLETED
PF-06939926 Myopathies Phase 3 NCT04281485 Study to Evaluate the Safety and Efficacy of PF-06939926 for the Treatment of Duchenne Muscular Dystrophy ACTIVE_NOT_RECRUITING
SRP-1003 IV Infusion Myopathies Phase 1/2 NCT06138743 Study of SRP-1003 in Participants With Type 1 Myotonic Dystrophy ENROLLING_BY_INVITATION
Nipocalimab Lupus Phase 3 NCT07438496 GARDENIA-SLE — A Study of Nipocalimab in Adults With Moderate to Severe Systemic Lupus Erythematosus RECRUITING
BI 3000202 Lupus Phase 2 NCT07409181 A Study to Test Whether Different Doses of BI 3000202 Help People With Systemic Lupus Erythematosus (SLE) RECRUITING
Vonsetamig Lupus Phase 1 NCT06975787 Dose Escalation Study With Bispecific Antibodies in Adult Participants With Lupus Nephritis RECRUITING
Histotripsie — HistoSonics Edison System Cancer Non applicable NCT07180706 To Evaluate the Safety and Efficacy of Histotripsy for the Symptom Relief of Inoperable Abdominal Tumors NOT_YET_RECRUITING
Xanomeline/Trospium Chloride Capsule Alzheimer Phase 3 NCT07011732 A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-1) RECRUITING
Adefovir Dipivoxil and Lamivudine Cancer À vérifier NCT00455091 A Phase III Study in Post-operative HBV-related Hepatocellular Carcinoma TERMINATED
Pembrolizumab Parkinson Phase 3 NCT03358472 Pembrolizumab Plus Epacadostat, Pembrolizumab Monotherapy, and the EXTREME Regimen in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (KEYNOTE-669/ECHO-304) COMPLETED
AZD9291 Cancer Phase 2 NCT02811354 Phase II Study of AZD9291 in Advanced Stage NSCLC With EGFR and T790M Mutations Detected in Plasma Ct-DNA UNKNOWN
Sacituzumab govitecan-hziy Cancer Phase 3 NCT06486441 Study of Sacituzumab Govitecan Versus Treatment of Physician's Choice in Participants With Endometrial Cancer After Platinum-Based Chemotherapy and Immunotherapy (ASCENT-GYN-01/GOG-3104/ENGOT-en26) ACTIVE_NOT_RECRUITING