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Synchronisé depuis ClinicalTrials.gov — NCT07476287

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43
MoléculeIndication / populationPhaseNCTTitreStatut
XEN1101 Épilepsie Phase 2 NCT03796962 X-TOLE — A Study to Evaluate XEN1101 as Adjunctive Therapy in Focal Epilepsy ACTIVE_NOT_RECRUITING
Maridebart cafraglutide Insuffisance cardiaque Phase 3 NCT07037459 MARITIME-HF — Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity RECRUITING
Selatogrel Maladie coronarienne Phase 3 NCT04957719 SOS-AMI — Selatogrel Outcome Study in Suspected Acute Myocardial Infarction ENROLLING_BY_INVITATION
Adagrasib Cancer Phase 2/3 NCT04613596 Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7 RECRUITING
RapidPulseTM Aspiration System Accident vasculaire cérébral Non applicable NCT06029491 TURBO — Thrombectomy Using Pulsed Aspiration for Reperfusion of Brain Occlusions RECRUITING
BMS-986504 Cancer Phase 2/3 NCT07063745 MountainTAP-29 — A Study to Compare the Combination of Navlimetostat (BMS-986504) With Pembrolizumab and Chemotherapy Versus Placebo Plus Pembrolizumab and Chemotherapy in First-line Metastatic Non-small Cell Lung Cancer Participants With Homozygous MTAP Deletion RECRUITING
Nivolumab Cancer Phase 3 NCT06561386 RELATIVITY1093 — A Study to Compare the Efficacy of Nivolumab and Relatlimab Plus Chemotherapy vs Pembrolizumab Plus Chemotherapy for Stage IV/Recurrent Non-squamous Non-small Cell Lung Cancer With PD-L1 Expression ≥ 1% RECRUITING
Tenecteplase Accident vasculaire cérébral Phase 3 NCT07361302 TENACITY — A Study to Test if Tenecteplase Helps People to Recover From an Acute Stroke When Given More Than 4.5 Hours After the Person Was Last Seen Well RECRUITING
Vicadrostat Insuffisance cardiaque Phase 3 NCT06424288 A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure RECRUITING
Vicadrostat Insuffisance cardiaque Phase 3 NCT06935370 A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart RECRUITING
SherpaPak Cardiac Transport System Insuffisance cardiaque À vérifier NCT04141605 GUARDIAN — Global Utilization And Registry Database for Improved heArt preservatioN ENROLLING_BY_INVITATION
Efgartigimod PH20 SC Myopathies Phase 3 NCT05979441 ALKIVIA+ — A Study to Assess the Long-term Safety and Efficacy of a Subcutaneous Formulation of Efgartigimod in Adults With Active Idiopathic Inflammatory Myopathy ENROLLING_BY_INVITATION
ZL-1310 Cancer Phase 1 NCT06179069 A Study of ZL-1310 in Subjects With Small Cell Lung Cancer RECRUITING
Epcoritamab SEP Phase 2 NCT05660967 EPCORE DLBCL-3 — Subcutaneous Epcoritamab With or Without Lenalidomide as First Line Therapy for Diffuse Large B-Cell Lymphoma TERMINATED
PF-08634404 Cancer Phase 2 NCT07476287 Symbiotic-Lung-14: A Study to Learn About the Study Medicine Called PF08634404 in Combination With Chemotherapy in Adult Participants With Transformed Small Cell Lung Cancer RECRUITING
Ocrelizumab SEP Phase 3 NCT03599245 This is an Extension Study of the Roche P-trials to Investigate Safety and Effectiveness of Ocrelizumab in Participants With Multiple Sclerosis (MS) COMPLETED
doxecitine and doxribtimine Myopathies Phase 2 NCT06754098 Doxecitin and Doxribthymine in Adult Subjects With Thymidine Kinase 2 (TK2) Deficiency RECRUITING
Zanidatamab Cancer Phase 3 NCT06282575 Efficacy and Safety of Zanidatamab With Standard-of-care Therapy Against Standard-of-care Therapy for Advanced HER2-positive Biliary Tract Cancer RECRUITING
RO7126209 Alzheimer Phase 1/2 NCT04639050 Brainshuttle AD: A Multiple Ascending Dose Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7126209 Following Intravenous Infusion in Participants With Prodromal or Mild to Moderate Alzheimer's Disease ACTIVE_NOT_RECRUITING
Sonrotoclax Cancer Phase 3 NCT07277231 A Study to Investigate Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Acalabrutinib in Adults With Previously Untreated Chronic Lymphocytic Leukemia RECRUITING
Prasinezumab Parkinson Phase 2 NCT04777331 PADOVA — A Study to Evaluate the Efficacy and Safety of Intravenous Prasinezumab in Participants With Early Parkinson's Disease ACTIVE_NOT_RECRUITING
Inavolisib Cancer Phase 3 NCT06790693 INAVO123 — A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer RECRUITING
Lasmiditan Migraine Phase 3 NCT04396236 PIONEER-PEDS1 — A Study of Lasmiditan (LY573144) Treatment in Children Aged 6 to 17 With Migraine TERMINATED
Nerandomilast Myopathies Phase 3 NCT07789015 VERANDA™-IIM — A Study to Understand How Nerandomilast Works in People With Active Idiopathic Inflammatory Myopathies NOT_YET_RECRUITING
Inavolisib Cancer Phase 2 NCT07054190 A Study to Test Inavolisib Treatments in Participants With Early-Stage, PIK3CA-Mutated Breast Cancer RECRUITING
Obinutuzumab Lupus Phase 3 NCT04221477 REGENCY — A Study to Evaluate the Efficacy and Safety of Obinutuzumab in Participants With ISN/RPS 2003 Class III or IV Lupus Nephritis ACTIVE_NOT_RECRUITING
PF-06821497 Cancer Phase 3 NCT06629779 A Study to Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic Castration-resistant Prostate Cancer. RECRUITING
Lasmiditan Migraine Phase 3 NCT04396574 PIONEER-PEDS2 — A 12-Month Study of Lasmiditan (LY573144) Treatment in Children Aged 6 to 17 With Migraine TERMINATED
Adagrasib Cancer Phase 3 NCT06875310 A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4) RECRUITING
Cenerimod 0.5 mg Lupus Phase 2 NCT03742037 Efficacy and Safety of Four Doses of Cenerimod Compared to Placebo in Adult Subjects With Active Systemic Lupus Erythematosus COMPLETED
Trontinemab Alzheimer Phase 3 NCT07170150 TRONTIER 2 — A Clinical Trial of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease ACTIVE_NOT_RECRUITING
Inebilizumab Lupus Phase 2 NCT06570798 A Phase 2 Master Protocol Assessing Inebilizumab and Blinatumomab in Autoimmune Diseases RECRUITING
PF-06823859 Lupus Phase 2 NCT05879718 A Study to Learn About the Study Medicine (PF-06823859) in Adults With Active CLE or SLE With Skin Symptoms. TERMINATED
Vonsetamig Lupus Phase 1 NCT06975787 Dose Escalation Study With Bispecific Antibodies in Adult Participants With Lupus Nephritis RECRUITING
XEN1101 Épilepsie Phase 3 NCT05667142 X-ACKT — A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures RECRUITING
RO7269162 Alzheimer Phase 2 NCT06402838 A Study to Evaluate the Safety and Biomarker Effects of RO7269162 in Participants at Risk for or at the Prodromal Stage of Alzheimer's Disease (AD) ACTIVE_NOT_RECRUITING
KarXT Alzheimer Phase 3 NCT06976203 A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2) RECRUITING
Orelabrutinib SEP Phase 3 NCT07067463 A Study of Orelabrutinib in Patients With Primary Progressive Multiple Sclerosis RECRUITING
Pembrolizumab Parkinson Phase 3 NCT03358472 Pembrolizumab Plus Epacadostat, Pembrolizumab Monotherapy, and the EXTREME Regimen in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (KEYNOTE-669/ECHO-304) COMPLETED
Botulinum toxin type A Migraine Phase 3 NCT06047457 E-BEOND — A Study to Evaluate the Effectiveness and Safety of Dysport® for the Prevention of Episodic Migraine in Adults ACTIVE_NOT_RECRUITING
Botulinum toxin type A Migraine Phase 3 NCT06047444 C-BEOND — A Study to Evaluate the Effectiveness and Safety of Dysport® for the Prevention of Chronic Migraine in Adults ACTIVE_NOT_RECRUITING
RO7507062 Lupus Phase 1 NCT05835986 A First-in-Human Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of RO7507062 in Participants With Systemic Lupus Erythematosus ACTIVE_NOT_RECRUITING
GLPG1690 SEP Phase 2 NCT03798366 A Clinical Study to Test How Effective and Safe GLPG1690 is for Participants With Systemic Sclerosis COMPLETED