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Toutes les maladies
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Périmètre
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10635 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 5743
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| LVIVO-TaVec400 product NCT07583030 · A Clinical Study to Evaluate LVIVO-TaVec400 for the Treatment of Relapsed/Refrac… | Myasthénie | À vérifier | Phase 1 | WITHDRAWN | This is a prospective, single-arm, open-label dose-escalation clinical stu… À vérifier | ClinicalTrials.gov 2026-10-11 04:37:11 | Détail |
| DS-5141b NCT04433234 · Long-term, Extension Study of DS-5141b in Patients With Duchenne Muscular Dystro… | Myopathies | À vérifier | Phase 2 | ACTIVE_NOT_RECRUITING | This is a multicenter, open-label, long-term, extension, phase 2 study to… À vérifier | ClinicalTrials.gov 2026-10-11 04:37:07 | Détail |
| ELEVIDYS NCT07542314 · ENHANCE — Study to Evaluate the Safety and Effectiveness of ELEVIDYS in Particip… | Myopathies | À vérifier | Phase 4 | RECRUITING | The primary objective of this study is to evaluate acute liver injury (ALI… À vérifier | ClinicalTrials.gov 2026-10-11 04:37:07 | Détail |
| garetosmab NCT07559513 · OPTIMA-2 — A Study to Investigate the Safety, Pharmacokinetics (PK), and Efficac… | Myopathies | À vérifier | Phase 3 | NOT_YET_RECRUITING | This study is researching an experimental drug called garetosmab, referred… À vérifier | ClinicalTrials.gov 2026-10-11 04:37:07 | Détail |
| LabVax 3(22)-23 and GM-CSF (adjuvant) in combination with pembrolizum… NCT07859592 · Labyrinthin Vaccination in Veterans With Lung Adenocarcinoma | Myopathies | À vérifier | Phase 2 | NOT_YET_RECRUITING | This phase 2 trial tests the safety and effectiveness of a cancer vaccine… À vérifier | ClinicalTrials.gov 2026-10-11 04:37:07 | Détail |
| Nerivio treatment NCT07639944 · An Open Label Study Assessing REN Treatment in Headache Management in Temporoman… | Myopathies | Traitement symptomatique | Non applicable | RECRUITING | Temporomandibular disorders (TMD) encompass a group of conditions involvin… À vérifier | ClinicalTrials.gov 2026-10-11 04:37:07 | Détail |
| Photobiomodulation (Low-Level Laser Therapy) NCT07546539 · Photobiomodulation in Chronic Fatigue Syndrome | Myopathies | Traitement symptomatique | Non applicable | RECRUITING | The goal of this clinical trial is to evaluate whether photobiomodulation… À vérifier | ClinicalTrials.gov 2026-10-11 04:37:07 | Détail |
| SAT-3247 NCT06867107 · An Open-label Long-term Follow-up Study of SAT-3247 for Participants With Duchen… | Myopathies | À vérifier | Phase 2 | ENROLLING_BY_INVITATION | Phase 2a trial of SAT-3247 in ambulatory DMD patients aged ≥ 7 and \< 10 y… À vérifier | ClinicalTrials.gov 2026-10-11 04:37:07 | Détail |
| SRP-1001 for Injection NCT06131983 · Study of SRP-1001 in Adult and Adolescent Participants With Facioscapulohumeral… | Myopathies | À vérifier | Phase 1/2 | ENROLLING_BY_INVITATION | The purpose of this study is to evaluate the safety, tolerability, pharmac… À vérifier | ClinicalTrials.gov 2026-10-11 04:37:07 | Détail |
| SRP-1003 IV Infusion NCT06138743 · Study of SRP-1003 in Participants With Type 1 Myotonic Dystrophy | Myopathies | À vérifier | Phase 1/2 | ENROLLING_BY_INVITATION | This is a phase 1/2a double-blinded, placebo-controlled, dose-escalating s… À vérifier | ClinicalTrials.gov 2026-10-11 04:37:07 | Détail |
| VM100 Nutritional Supplement NCT07766980 · Evaluating VM100 Nutritional Supplement for Improving Quality of Life in Duchenn… | Myopathies | Traitement symptomatique | Phase 2 | RECRUITING | This pilot study will investigate the potential efficacy of VM100, a nutri… À vérifier | ClinicalTrials.gov 2026-10-11 04:37:07 | Détail |
| Ataluren NCT01247207 · Study of Ataluren in Previously Treated Participants With Nonsense Mutation Dyst… | Myopathies | À vérifier | Phase 3 | TERMINATED | Duchenne/Becker muscular dystrophy (DMD/BMD) is a genetic disorder that de… À vérifier | ClinicalTrials.gov 2026-10-11 04:37:06 | Détail |
| Botulinum Toxin A (Botox ) NCT07867379 · Botulinum Toxin Type A Versus Triamcinolone for Facial Myalgia | Myopathies | Traitement symptomatique | Phase 4 | NOT_YET_RECRUITING | This single-blind randomized controlled trial aims to compare the therapeu… À vérifier | ClinicalTrials.gov 2026-10-11 04:37:06 | Détail |
| electro-stimulation suit NCT07202195 · HANDS-MS — At Home Use of Stimulation Suits for Managing MS Symptoms | Myopathies | Traitement symptomatique | Non applicable | RECRUITING | This study is being carried out at Multiple Sclerosis (MS) centers to eval… À vérifier | ClinicalTrials.gov 2026-10-11 04:37:06 | Détail |
| SPIO® Core-MAX® Expedition thoracolumbosacral orthosis NCT06027580 · Orthosis to Improve Trunk Control in Infants Age 6-18 Months | Myopathies | À vérifier | À vérifier | COMPLETED | The purpose of this study is to determine the impact of the SPIO® Core-MAX… À vérifier | ClinicalTrials.gov 2026-10-11 04:37:06 | Détail |
| Litifilimab NCT05352919 · EMERALD — A Study to Learn More About the Long-Term Safety of Litifilimab (BIIB0… | Lupus | Traitement symptomatique · Thérapie génique | Phase 3 | ENROLLING_BY_INVITATION | In this study, researchers will learn more about a study drug called litif… À vérifier | ClinicalTrials.gov 2026-10-11 04:37:01 | Détail |
| Belimumab Injection NCT03747159 · SynBioSe-2 — Synergetic B-cell Immunomodulation in SLE - 2nd Study. | Lupus | Immunomodulation | Phase 3 | COMPLETED | In follow-up of the previous SynBioSe Study the present study is a randomi… À vérifier | ClinicalTrials.gov 2026-10-11 04:37:00 | Détail |
| CM355 NCT07104344 · Study of CM355 in Patients With Systemic Lupus Erythematosus | Lupus | À vérifier | Non applicable | ACTIVE_NOT_RECRUITING | This study was designed to investigate the safety and efficacy of CM355 in… À vérifier | ClinicalTrials.gov 2026-10-11 04:37:00 | Détail |
| Daratumumab NCT04868838 · Daratumumab to Treat Active Lupus Nephritis | Lupus | À vérifier | Phase 2 | ACTIVE_NOT_RECRUITING | Multiple myeloma (MM) is a plasma cell disease characterized by the growth… À vérifier | ClinicalTrials.gov 2026-10-11 04:37:00 | Détail |
| LY4298445 NCT07276958 · A Study of LY4298445 in Healthy Participants and Participants With Systemic Lupu… | Lupus | À vérifier | Phase 1 | RECRUITING | The purpose of this study is to investigate the safety and tolerability of… À vérifier | ClinicalTrials.gov 2026-10-11 04:37:00 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4871
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Effects of continuous vs. intermittent transcutaneous electrical stim… Transcutaneous electrical nerve stimulation unit (TENS) · PMID 41866984 | Maladie rénale chronique | Traitement symptomatique | Publication | PubMed | Voir la publication source To compare the effects of two transcutaneous electrical stimulation (TES) patterns applied to the auricular branches of… | Cranio : the journal of craniomandibular practice 2026-11-08 04:38:07 | Source |
| Optimizing Percutaneous Tibial Nerve Stimulation Intensity for Overac… Transcutaneous electrical nerve stimulation unit (TENS) · PMID 42554545 | Maladie rénale chronique | Traitement symptomatique | Publication | PubMed | Voir la publication source Overactive bladder (OAB) is a significant global health issue. The standard percutaneous tibial nerve stimulation (PTNS… | Neuromodulation : journal of the International Neuromo… 2026-11-08 04:38:07 | Source |
| Transcutaneous auricular vagus nerve stimulation improves dysautonomi… Transcutaneous electrical nerve stimulation unit (TENS) · PMID 42802247 | Maladie rénale chronique | Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source Autonomic nervous system dysfunction is highly prevalent in hypermobile Ehlers-Danlos syndrome (hEDS) and contributes s… | Neurological sciences : official journal of the Italia… 2026-11-08 04:38:07 | Source |
| Factors associated with high-flow therapy failure in COVID-19-related… Non-Invasive Positive Pressure Ventilation · PMID 42888091 | Maladie rénale chronique | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source The optimal selection of non-invasive respiratory support for patients with COVID-19-related acute hypoxemic respirator… | Enfermedades infecciosas y microbiologia clinica (Engl… 2026-11-08 04:38:06 | Source |
| High-Flow Nasal Cannula in Adult Acute Care: Physiological Mechanisms… Non-Invasive Positive Pressure Ventilation · PMID 42942512 | Maladie rénale chronique | À vérifier | Publication | PubMed | Voir la publication source High-flow nasal cannula (HFNC) oxygen therapy is widely used in emergency, intensive care, perioperative, and procedura… | Medicina (Kaunas, Lithuania) 2026-11-08 04:38:06 | Source |
| Impact of respiratory support on time to achieve full oral feeding in… Non-Invasive Positive Pressure Ventilation · PMID 42871336 | Maladie rénale chronique | À vérifier | Publication | PubMed | Voir la publication source Very low birth weight infants often require respiratory support, which may delay full oral feeding. The independent rol… | Frontiers in pediatrics 2026-11-08 04:38:06 | Source |
| A comparative analysis of 3MAX aspiration versus 3 mm Trevo Retriever… Thromboaspiration catheter · PMID 31243066 | Accident vasculaire cérébral | À vérifier | Publication | PubMed | Voir la publication source Although aspiration and stent retriever thrombectomy perform similarly in proximal occlusions, no comparative series ar… | Journal of neurointerventional surgery 2026-11-08 04:38:02 | Source |
| Percutaneous Pulmonary Thrombectomy Beyond Acute Pulmonary Embolism:… Thromboaspiration catheter · PMID 38385241 | Accident vasculaire cérébral | Thérapie génique | Publication | PubMed | Voir la publication source Subacute massive pulmonary embolism is an uncommon manifestation of severe pulmonary embolism associated with poor prog… | Journal of endovascular therapy : an official journal… 2026-11-08 04:38:02 | Source |
| Simplified classification of cavernous internal carotid artery tortuo… Thromboaspiration catheter · PMID 35475775 | Hypertension artérielle · Accident vasculaire cérébral | Thérapie génique | Publication | PubMed | Voir la publication source Thromboaspiration catheters are increasingly used for the endovascular treatment of large vessel stroke (LVS), while to… | Neurological research 2026-11-08 04:38:02 | Source |
| Multifocal continuous theta burst stimulation in idiopathic generaliz… Continuous Theta Burst Stimulation (cTBS) · PMID 42731195 | Accident vasculaire cérébral | Traitement symptomatique | Publication | PubMed | Voir la publication source Idiopathic generalized epilepsy (IGE) is a disorder of the cortico-subcortical networks. Continuous theta burst stimula… | Clinical neurophysiology : official journal of the Int… 2026-11-08 04:38:00 | Source |
| Optimizing brain functional-structural architecture with cTBS to redu… Continuous Theta Burst Stimulation (cTBS) · PMID 42457860 | Accident vasculaire cérébral | À vérifier | Publication | PubMed | Voir la publication source Alcohol use disorder (AUD) is characterized by high relapse rates, necessitating novel interventions. Continuous theta-… | Molecular psychiatry 2026-11-08 04:38:00 | Source |
| Digital Outreach to Improve Statin Refills in Patients With Low Stati… Cordio System · PMID 42667613 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Statin nonadherence is a leading, addressable driver of preventable cardiovascular events. Although health systems rout… | JAMA 2026-11-08 04:37:54 | Source |
| Endovascular ablation of the right greater splanchnic nerve for the m… Right Greater Splanchnic Nerve (GSN) ablation · PMID 42257781 | Insuffisance cardiaque | Traitement symptomatique | Publication | PubMed | Voir la publication source Heart failure with preserved ejection fraction (HFpEF) remains difficult to manage because conventional therapies often… | The Egyptian heart journal : (EHJ) : official bulletin… 2026-11-08 04:37:54 | Source |
| Incidence, medical therapy, and outcomes in heart failure with improv… Cordio System · PMID 42702264 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source To assess the incidence of heart failure with improved ejection fraction (HFimpEF) across guideline definitions (ACC/AH… | American heart journal 2026-11-08 04:37:54 | Source |
| Relationship Between the Azygos Vein and the Greater Splanchnic Nerve… Right Greater Splanchnic Nerve (GSN) ablation · PMID 42249803 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Although ablation of the greater splanchnic nerve is now being used to treat some patients with heart failure, the anat… | Clinical anatomy (New York, N.Y.) 2026-11-08 04:37:54 | Source |
| Validation of the PREVENT-HF Risk Prediction Equation in US Veterans. Cordio System · PMID 42969140 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Résumé non disponible dans la base locale. | Circulation 2026-11-08 04:37:54 | Source |
| Changes in right ventricular-pulmonary artery coupling after transcat… Tricuspid Transcatheter Edge-to-Edge Repair (TEER) · PMID 42822601 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Right ventricular-pulmonary artery (RV-PA) coupling is an established marker of prognosis in mitral regurgitation (MR),… | International journal of cardiology 2026-11-08 04:37:47 | Source |
| Intraprocedural evaluation of residual mitral and tricuspid regurgita… Tricuspid Transcatheter Edge-to-Edge Repair (TEER) · PMID 42982241 | Maladie coronarienne | À vérifier | Publication | PubMed | Voir la publication source Transcatheter edge-to-edge repair (TEER) has emerged as an established therapeutic option for selected patients with se… | International journal of cardiology 2026-11-08 04:37:47 | Source |
| Tricuspid transcatheter edge-to-edge repair versus transcatheter tric… Tricuspid Transcatheter Edge-to-Edge Repair (TEER) · PMID 42989943 | Maladie coronarienne | À vérifier | Publication | PubMed | Voir la publication source Recent clinical studies of tricuspid transcatheter edge-to-edge repair (T-TEER) and transcatheter tricuspid valve repla… | Current opinion in cardiology 2026-11-08 04:37:47 | Source |
| Automated Production of Gene-Edited CAR-T Cells for People Living wit… RAPA-501 Autologous T stem cells · PMID 42847201 | Cancer | Thérapie cellulaire · Thérapie génique | Publication | PubMed | Voir la publication source Adoptive transfer of gene-modified autologous T cells, for example, expressing chimeric antigen receptors (CARs), is a… | Human gene therapy 2026-11-08 04:37:39 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||