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10635 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 5743
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Brain Interchange System NCT05439655 · Acute Recording of Stereotyped High-Frequency Oscillations | Épilepsie | À vérifier | Non applicable | ACTIVE_NOT_RECRUITING | Overall, this study will investigate the functional utility of stereotyped… À vérifier | ClinicalTrials.gov 2026-10-18 04:36:32 | Détail |
| Ear-SD NCT06598189 · EarSD001 — Ear-Seizure Detection (EarSD) Study | Épilepsie | À vérifier | Non applicable | RECRUITING | The proposed study is an investigator-initiated study that aims to measure… À vérifier | ClinicalTrials.gov 2026-10-18 04:36:32 | Détail |
| Exablate 4000 Transcranial MRgfUS System NCT06292494 · Focused Ultrasound for Drug-resistant Epilepsy | Épilepsie | À vérifier | Non applicable | RECRUITING | Focused ultrasound (FUS) has been shown to differentially lesion or modula… À vérifier | ClinicalTrials.gov 2026-10-18 04:36:32 | Détail |
| Ketogenic diet NCT06700811 · Ketogenic Diet for Prevention of Epileptic Spasms in Infantile Onset Genetic Epi… | Épilepsie | À vérifier | Phase 1 | TERMINATED | Epileptic spasms (ES) are a predominantly infantile seizure type observed… À vérifier | ClinicalTrials.gov 2026-10-18 04:36:32 | Détail |
| LP352 NCT06908226 · A Study to Investigate LP352 in Children and Adults With Developmental and Epile… | Épilepsie | À vérifier | Phase 3 | ENROLLING_BY_INVITATION | This (DEEp OLE Study) is a multicentre, open-label study to investigate th… À vérifier | ClinicalTrials.gov 2026-10-18 04:36:32 | Détail |
| Non-invasive Temporal Interference (TI) Stimulation Targeting Bilater… NCT07434986 · TI-HPC-TLE — Overnight TI in TLE | Épilepsie | À vérifier | Non applicable | RECRUITING | The goal of this clinical trial is to gauge whether overnight, non-invasiv… À vérifier | ClinicalTrials.gov 2026-10-18 04:36:32 | Détail |
| Study Subjects NCT07877896 · A Device to Prevent Unexpected Death in Epilepsy | Épilepsie | À vérifier | Non applicable | ACTIVE_NOT_RECRUITING | The goal of this study is to assess the performance of a commercial sheet… À vérifier | ClinicalTrials.gov 2026-10-18 04:36:32 | Détail |
| Temporal Interference Stimulation NCT07764718 · Temporal Interference Brain Stimulation for Adults With Drug-Resistant Epilepsy… | Épilepsie | Traitement symptomatique | Non applicable | RECRUITING | This clinical trial will evaluate the efficacy of accelerated Temporal Int… À vérifier | ClinicalTrials.gov 2026-10-18 04:36:32 | Détail |
| Ultrasound-guided intermediate cervical plexus block NCT07689617 · Ultrasound-Guided Intermediate Cervical Plexus Block for Postoperative Analgesia… | Épilepsie | Traitement symptomatique | À vérifier | COMPLETED | This retrospective cohort study evaluated the medical records of adult pat… À vérifier | ClinicalTrials.gov 2026-10-18 04:36:32 | Détail |
| Xcopri NCT05067634 · Safety and Efficacy Study of Cenobamate in Pediatric Subjects 2-17 Years of Age… | Épilepsie | À vérifier | Phase 3 | COMPLETED | Primary objective: To evaluate the safety and tolerability of cenobamate i… À vérifier | ClinicalTrials.gov 2026-10-18 04:36:32 | Détail |
| Acoramidis NCT03536767 · Open-Label Study of AG10 in Patients With Cardiomyopathy | Maladie d’Alzheimer | Traitement symptomatique | Phase 2 | TERMINATED | Transthyretin amyloidosis (ATTR) is a disease where the normally occurring… À vérifier | ClinicalTrials.gov 2026-10-18 04:36:27 | Détail |
| Continuous Glucose Monitoring System (CGMS) NCT04201600 · Glucose Variability and Cognition in Prediabetes | Maladie d’Alzheimer | À vérifier | À vérifier | COMPLETED | This study examines the association of variability in glucose values over… À vérifier | ClinicalTrials.gov 2026-10-18 04:36:27 | Détail |
| DaTscan NCT03019757 · Distinguishing Between Alzheimer's Disease, Lewy Body Dementia, and Parkinson's… | Maladie d’Alzheimer | À vérifier | À vérifier | RECRUITING | The study is designed to characterize the clinical, neuropsychological, po… À vérifier | ClinicalTrials.gov 2026-10-18 04:36:27 | Détail |
| Donanemab NCT07838155 · A Study of Donanemab (LY3002813) in Participants With Early Symptomatic Alzheime… | Maladie d’Alzheimer | Traitement symptomatique | Phase 4 | NOT_YET_RECRUITING | The main purpose of this study is to evaluate the effects of donanemab (LY… À vérifier | ClinicalTrials.gov 2026-10-18 04:36:27 | Détail |
| GE-287 NCT07873463 · Flutemetamol F 18 Injection Formulation Comparison | Maladie d’Alzheimer | À vérifier | Phase 2 | NOT_YET_RECRUITING | VIZAMYL (flutemetamol F 18 injection) is a drug used during Positron Emiss… À vérifier | ClinicalTrials.gov 2026-10-18 04:36:27 | Détail |
| Hip or Knee Arthroplasty Under Spinal Anesthesia NCT07871487 · TAU-PET — Tau Pathology in the Brain After Hip or Knee Replacement Surgery | Maladie d’Alzheimer | Immunomodulation | À vérifier | RECRUITING | The goal of this observational study is to study whether major surgery is… À vérifier | ClinicalTrials.gov 2026-10-18 04:36:27 | Détail |
| Medical yoga NCT07872956 · Feasibility Study of a Co-Designed Gamified Medical Yoga App for Home-Based Canc… | Maladie d’Alzheimer | À vérifier | Non applicable | RECRUITING | The project aims to develop a gamified medical yoga intervention through c… À vérifier | ClinicalTrials.gov 2026-10-18 04:36:27 | Détail |
| KarXT NCT06937229 · A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agi… | Maladie d’Alzheimer | À vérifier | Phase 3 | RECRUITING | The purpose of this study is to evaluate the efficacy and safety of KarXT… À vérifier | ClinicalTrials.gov 2026-10-18 04:36:26 | Détail |
| Donanemab NCT06566170 · A Real-World Comparative Study of Donanemab (LY3002813) Plus Usual Care Versus U… | Maladie d’Alzheimer | Traitement symptomatique | À vérifier | RECRUITING | The main purpose of this study is to evaluate the effects of donanemab (LY… À vérifier | ClinicalTrials.gov 2026-10-18 04:36:25 | Détail |
| GLP-1 Receptor Agonists NCT07677865 · GLP1-AD-TTE — GLP-1 Receptor Agonists and Alzheimer's Disease: A Multi-National… | Maladie d’Alzheimer | Ralentissement de la progression | À vérifier | WITHDRAWN | Background: Seven large real-world cohort studies (N \> 4 million) have co… À vérifier | ClinicalTrials.gov 2026-10-18 04:36:25 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4871
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Effects of continuous vs. intermittent transcutaneous electrical stim… Transcutaneous electrical nerve stimulation unit (TENS) · PMID 41866984 | Maladie rénale chronique | Traitement symptomatique | Publication | PubMed | Voir la publication source To compare the effects of two transcutaneous electrical stimulation (TES) patterns applied to the auricular branches of… | Cranio : the journal of craniomandibular practice 2026-11-08 04:38:07 | Source |
| Optimizing Percutaneous Tibial Nerve Stimulation Intensity for Overac… Transcutaneous electrical nerve stimulation unit (TENS) · PMID 42554545 | Maladie rénale chronique | Traitement symptomatique | Publication | PubMed | Voir la publication source Overactive bladder (OAB) is a significant global health issue. The standard percutaneous tibial nerve stimulation (PTNS… | Neuromodulation : journal of the International Neuromo… 2026-11-08 04:38:07 | Source |
| Transcutaneous auricular vagus nerve stimulation improves dysautonomi… Transcutaneous electrical nerve stimulation unit (TENS) · PMID 42802247 | Maladie rénale chronique | Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source Autonomic nervous system dysfunction is highly prevalent in hypermobile Ehlers-Danlos syndrome (hEDS) and contributes s… | Neurological sciences : official journal of the Italia… 2026-11-08 04:38:07 | Source |
| Factors associated with high-flow therapy failure in COVID-19-related… Non-Invasive Positive Pressure Ventilation · PMID 42888091 | Maladie rénale chronique | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source The optimal selection of non-invasive respiratory support for patients with COVID-19-related acute hypoxemic respirator… | Enfermedades infecciosas y microbiologia clinica (Engl… 2026-11-08 04:38:06 | Source |
| High-Flow Nasal Cannula in Adult Acute Care: Physiological Mechanisms… Non-Invasive Positive Pressure Ventilation · PMID 42942512 | Maladie rénale chronique | À vérifier | Publication | PubMed | Voir la publication source High-flow nasal cannula (HFNC) oxygen therapy is widely used in emergency, intensive care, perioperative, and procedura… | Medicina (Kaunas, Lithuania) 2026-11-08 04:38:06 | Source |
| Impact of respiratory support on time to achieve full oral feeding in… Non-Invasive Positive Pressure Ventilation · PMID 42871336 | Maladie rénale chronique | À vérifier | Publication | PubMed | Voir la publication source Very low birth weight infants often require respiratory support, which may delay full oral feeding. The independent rol… | Frontiers in pediatrics 2026-11-08 04:38:06 | Source |
| A comparative analysis of 3MAX aspiration versus 3 mm Trevo Retriever… Thromboaspiration catheter · PMID 31243066 | Accident vasculaire cérébral | À vérifier | Publication | PubMed | Voir la publication source Although aspiration and stent retriever thrombectomy perform similarly in proximal occlusions, no comparative series ar… | Journal of neurointerventional surgery 2026-11-08 04:38:02 | Source |
| Percutaneous Pulmonary Thrombectomy Beyond Acute Pulmonary Embolism:… Thromboaspiration catheter · PMID 38385241 | Accident vasculaire cérébral | Thérapie génique | Publication | PubMed | Voir la publication source Subacute massive pulmonary embolism is an uncommon manifestation of severe pulmonary embolism associated with poor prog… | Journal of endovascular therapy : an official journal… 2026-11-08 04:38:02 | Source |
| Simplified classification of cavernous internal carotid artery tortuo… Thromboaspiration catheter · PMID 35475775 | Hypertension artérielle · Accident vasculaire cérébral | Thérapie génique | Publication | PubMed | Voir la publication source Thromboaspiration catheters are increasingly used for the endovascular treatment of large vessel stroke (LVS), while to… | Neurological research 2026-11-08 04:38:02 | Source |
| Multifocal continuous theta burst stimulation in idiopathic generaliz… Continuous Theta Burst Stimulation (cTBS) · PMID 42731195 | Accident vasculaire cérébral | Traitement symptomatique | Publication | PubMed | Voir la publication source Idiopathic generalized epilepsy (IGE) is a disorder of the cortico-subcortical networks. Continuous theta burst stimula… | Clinical neurophysiology : official journal of the Int… 2026-11-08 04:38:00 | Source |
| Optimizing brain functional-structural architecture with cTBS to redu… Continuous Theta Burst Stimulation (cTBS) · PMID 42457860 | Accident vasculaire cérébral | À vérifier | Publication | PubMed | Voir la publication source Alcohol use disorder (AUD) is characterized by high relapse rates, necessitating novel interventions. Continuous theta-… | Molecular psychiatry 2026-11-08 04:38:00 | Source |
| Digital Outreach to Improve Statin Refills in Patients With Low Stati… Cordio System · PMID 42667613 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Statin nonadherence is a leading, addressable driver of preventable cardiovascular events. Although health systems rout… | JAMA 2026-11-08 04:37:54 | Source |
| Endovascular ablation of the right greater splanchnic nerve for the m… Right Greater Splanchnic Nerve (GSN) ablation · PMID 42257781 | Insuffisance cardiaque | Traitement symptomatique | Publication | PubMed | Voir la publication source Heart failure with preserved ejection fraction (HFpEF) remains difficult to manage because conventional therapies often… | The Egyptian heart journal : (EHJ) : official bulletin… 2026-11-08 04:37:54 | Source |
| Incidence, medical therapy, and outcomes in heart failure with improv… Cordio System · PMID 42702264 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source To assess the incidence of heart failure with improved ejection fraction (HFimpEF) across guideline definitions (ACC/AH… | American heart journal 2026-11-08 04:37:54 | Source |
| Relationship Between the Azygos Vein and the Greater Splanchnic Nerve… Right Greater Splanchnic Nerve (GSN) ablation · PMID 42249803 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Although ablation of the greater splanchnic nerve is now being used to treat some patients with heart failure, the anat… | Clinical anatomy (New York, N.Y.) 2026-11-08 04:37:54 | Source |
| Validation of the PREVENT-HF Risk Prediction Equation in US Veterans. Cordio System · PMID 42969140 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Résumé non disponible dans la base locale. | Circulation 2026-11-08 04:37:54 | Source |
| Changes in right ventricular-pulmonary artery coupling after transcat… Tricuspid Transcatheter Edge-to-Edge Repair (TEER) · PMID 42822601 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Right ventricular-pulmonary artery (RV-PA) coupling is an established marker of prognosis in mitral regurgitation (MR),… | International journal of cardiology 2026-11-08 04:37:47 | Source |
| Intraprocedural evaluation of residual mitral and tricuspid regurgita… Tricuspid Transcatheter Edge-to-Edge Repair (TEER) · PMID 42982241 | Maladie coronarienne | À vérifier | Publication | PubMed | Voir la publication source Transcatheter edge-to-edge repair (TEER) has emerged as an established therapeutic option for selected patients with se… | International journal of cardiology 2026-11-08 04:37:47 | Source |
| Tricuspid transcatheter edge-to-edge repair versus transcatheter tric… Tricuspid Transcatheter Edge-to-Edge Repair (TEER) · PMID 42989943 | Maladie coronarienne | À vérifier | Publication | PubMed | Voir la publication source Recent clinical studies of tricuspid transcatheter edge-to-edge repair (T-TEER) and transcatheter tricuspid valve repla… | Current opinion in cardiology 2026-11-08 04:37:47 | Source |
| Automated Production of Gene-Edited CAR-T Cells for People Living wit… RAPA-501 Autologous T stem cells · PMID 42847201 | Cancer | Thérapie cellulaire · Thérapie génique | Publication | PubMed | Voir la publication source Adoptive transfer of gene-modified autologous T cells, for example, expressing chimeric antigen receptors (CARs), is a… | Human gene therapy 2026-11-08 04:37:39 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||