Vue transversale de la maladie
Myopathies
Un même point d’entrée pour les études cliniques, les découvertes scientifiques, les publications et les pistes exploratoires présentes dans Biomedical Watch.
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1028 résultats correspondants
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dans le périmètre Myopathies
Niveau clinique
Études et traitements 434
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Clinical evaluation NCT07792434 · The NAP SAPS — Nociplastic Pain in Patients Diagnosed With Subacromial Pain Synd… | Myopathies | Traitement symptomatique | À vérifier | NOT_YET_RECRUITING | The goal of this prospective cohort study is to investigate whether pain p… À vérifier | ClinicalTrials.gov 2026-09-03 16:31:32 | Détail |
| Effectiveness of Brief Mindfulness-Based Interventions for Painful Te… NCT06582134 · NCT06582134 | Myopathies | Traitement symptomatique · Thérapie génique | Non applicable | COMPLETED | The goal of this clinical trial is to learn if brief mindfulness-based int… À vérifier | ClinicalTrials.gov 2026-09-03 16:31:32 | Détail |
| End-expiratory Transpulmonary Pressure-guided vs Electrical Impedance… NCT06697717 · End-expiratory Transpulmonary Pressure-guided vs Electrical Impedance Tomography… | Myopathies | À vérifier | Non applicable | COMPLETED | This study aims to adopt a randomized crossover design to compare the effe… À vérifier | ClinicalTrials.gov 2026-09-03 16:31:32 | Détail |
| GRASP-01-002 — Defining Endpoints in Becker Muscular Dystrophy NCT05257473 · NCT05257473 | Myopathies | À vérifier | À vérifier | ACTIVE_NOT_RECRUITING | This is a 24-month, observational study of 50 participants with Becker mus… À vérifier | ClinicalTrials.gov 2026-09-03 16:31:32 | Détail |
| INIT ART — Comparison of Integrated Neuromuscular Inhibition Techniqu… NCT07395154 · NCT07395154 | Myopathies | Ralentissement de la progression · Traitement symptomatique | Non applicable | COMPLETED | The goal of this clinical trial is to determine whether two manual therapy… À vérifier | ClinicalTrials.gov 2026-09-03 16:31:32 | Détail |
| Monoplace Hyperbaric Chamber (Class III medical device). NCT06082518 · PCS-HBOT — Improving Post COVID-19 Syndrome With Hyperbaric Oxygen Treatments | Myopathies | Traitement symptomatique | Non applicable | ACTIVE_NOT_RECRUITING | Over 500 million people have been infected with COVID-19, and to date, mor… À vérifier | ClinicalTrials.gov 2026-09-03 16:31:32 | Détail |
| Piloting a Novel Peer Support Pain Self-Management Intervention (Proj… NCT04229134 · NCT04229134 | Myopathies | Traitement symptomatique · Thérapie génique | Non applicable | COMPLETED | The proposed study will test the feasibility and acceptability of an 8-wee… À vérifier | ClinicalTrials.gov 2026-09-03 16:31:32 | Détail |
| Pulsed Electromagnetic Field Therapy NCT07802938 · Pulsed Electromagnetic Field Therapy Added to ESWT for Lateral Epicondylitis | Myopathies | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This randomized, sham-controlled, assessor-blinded clinical trial will eva… À vérifier | ClinicalTrials.gov 2026-09-03 16:31:32 | Détail |
| Resamirigene bilparvovec NCT03199469 · ASPIRO — A Study of AT132 in Young Children With X-Linked Myotubular Myopathy (X… | Myopathies | Traitement symptomatique · Thérapie génique | Phase 2/3 | ACTIVE_NOT_RECRUITING | X-linked myotubular myopathy (XLMTM) is a rare and serious condition prese… À vérifier | ClinicalTrials.gov 2026-09-03 16:31:32 | Détail |
| SFL-0821 for injection NCT07798609 · A Trial to Assess Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and… | Myopathies | À vérifier | Phase 1/2 | NOT_YET_RECRUITING | The purpose of this study is to evaluate the safety, tolerability, and pre… À vérifier | ClinicalTrials.gov 2026-09-03 16:31:32 | Détail |
| Triamcinolone injection to the shoulder, elbow, wrist, or hand NCT05292339 · Ketorolac in Upper Extremity Tendinopathy and Arthropathy | Myopathies | Immunomodulation · Traitement symptomatique | Phase 4 | RECRUITING | Osteoarthritis (OA) and inflammatory conditions of the tendons and joints… À vérifier | ClinicalTrials.gov 2026-09-03 16:31:32 | Détail |
| UX016 NCT07511556 · First-in-human Study of UX016 in GNEM | Myopathies | À vérifier | Phase 1/2 | RECRUITING | The goal of this study is to assess the safety and dose of UX016 and its i… À vérifier | ClinicalTrials.gov 2026-09-03 16:31:32 | Détail |
| Whole body vibration therapy NCT07286435 · The Effect of Whole-Body Vibration Therapy Following Botulinum Toxin A Injection… | Myopathies | Traitement symptomatique | Non applicable | RECRUITING | The purpose of this clinical study is to evaluate the effect of Whole Body… À vérifier | ClinicalTrials.gov 2026-09-03 16:31:32 | Détail |
| zeleciment basivarsen (DYNE-101) NCT07486934 · Efficacy, Safety, and Tolerability of Zeleciment Basivarsen (DYNE-101) in Partic… | Myopathies | À vérifier | Phase 3 | RECRUITING | The purpose of the study is to assess the efficacy, safety, and tolerabili… À vérifier | ClinicalTrials.gov 2026-09-03 16:31:32 | Détail |
| CTX112 Étude non communiquée | Lupus · Myopathies · Sclérose en plaques | Remyélinisation · Immunomodulation | Phase 1/2 | Prévu | This is a single-arm, open-label, multicenter, ascending dose Phase 1 stud… À vérifier | ClinicalTrials.gov 2026-09-03 | Détail |
| Sham whole body vibration therapy Étude non communiquée | Myopathies | Traitement symptomatique | Non applicable | Actif | The purpose of this clinical study is to evaluate the effect of Whole Body… À vérifier | ClinicalTrials.gov 2026-09-02 | Détail |
| Shoulder orthosis Étude non communiquée | Myopathies · Sclérose latérale amyotrophique | Traitement symptomatique | Non applicable | Terminé | The goal of this clinical trial is to investigate the effect of a muscle-m… À vérifier | ClinicalTrials.gov 2026-09-02 | Détail |
| AB-1003 dose level 1 NCT05230459 · A Study to Evaluate the Safety of AB-1003 (Previously LION-101) in Subjects With… | Myopathies | À vérifier | Phase 1/2 | ACTIVE_NOT_RECRUITING | The purpose of this study is to evaluate the safety and tolerability of a… À vérifier | ClinicalTrials.gov 2026-09-01 09:22:28 | Détail |
| Alternate-day prednisolone NCT07787689 · Intermittent vs Alternate Daily Regimen of Prednisolone in Ambulatory Boys With… | Myopathies | Thérapie génique | Non applicable | NOT_YET_RECRUITING | The alternate-day regimen is hypothesized to reduce hypothalamic-pituitary… À vérifier | ClinicalTrials.gov 2026-09-01 09:22:28 | Détail |
| ELEVIDYS NCT07542314 · ENHANCE — Study to Evaluate the Safety and Effectiveness of ELEVIDYS in Particip… | Myopathies | À vérifier | Phase 4 | NOT_YET_RECRUITING | The primary objective of this study is to evaluate acute liver injury (ALI… À vérifier | ClinicalTrials.gov 2026-09-01 09:22:28 | Détail |
Découverte scientifique
Recherches et trouvailles 0
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune trouvaille ne correspond aux filtres. | |||||||
Bibliographie
Publications 588
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| A mobile learning environment: a preliminary study of a developmental… test of walk · PMID 42485077 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source An embodied theory of development views an infant's mobility as a causal factor in their cognitive, language and motor… | Disability and rehabilitation. Assistive technology 2026-07-22 21:22:37 | Source |
| Feasibility of Real-Time Autonomous Functional Electrical Stimulation… test of walk · PMID 42484421 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source Freezing of gait is a debilitating walking disturbance that can severely worsen quality of life for people with Parkins… | The European journal of neuroscience 2026-07-22 21:22:37 | Source |
| Persistent hiccups following endobronchial ultrasound-guided transbro… baclofen · PMID 42471910 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a minimally invasive diagnostic procedu… | Respiratory medicine case reports 2026-07-22 21:22:33 | Source |
| Six approved drugs for alcohol use disorder: algorithms for their use… baclofen · PMID 42476146 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source The pharmacological management of alcohol use disorder (AUD) currently includes six medications approved by different r… | Alcohol and alcoholism (Oxford, Oxfordshire) 2026-07-22 21:22:33 | Source |
| Beyond intraocular pressure: vascular and metabolic modifiers of opti… Metformin · PMID 42484773 | Myopathies | Ralentissement de la progression · Thérapie génique | Publication | PubMed | Voir la publication source To critically integrate epidemiological, mechanistic, and clinical evidence linking systemic blood pressure dysregulati… | International ophthalmology 2026-07-22 21:21:06 | Source |
| Case Report: Early-onset euglycemic diabetic ketoacidosis following h… Metformin · PMID 42483676 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source Sodium-glucose cotransporter 2 (SGLT2) inhibitors are associated with euglycemic diabetic ketoacidosis (euDKA), typical… | Frontiers in endocrinology 2026-07-22 21:21:06 | Source |
| Interim Safety Profile From the Feasibility Study of the BrainGate Ne… BrainGate Neural Interface System · PMID 36639237 | Myopathies | Ralentissement de la progression | Publication | PubMed | Voir la publication source Brain-computer interfaces (BCIs) are being developed to restore mobility, communication, and functional independence to… | Neurology 2026-07-18 15:48:46 | Source |
| Neural Point-and-Click Communication by a Person With Incomplete Lock… BrainGate Neural Interface System · PMID 25385765 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source A goal of brain-computer interface research is to develop fast and reliable means of communication for individuals with… | Neurorehabilitation and neural repair 2026-07-18 15:48:46 | Source |
| Multimodality Risk Stratification in Athletes With Long QT Syndrome. Mexiletine · PMID 42460964 | Myopathies | Thérapie génique | Publication | PubMed | Voir la publication source Long QT syndrome has traditionally led to exercise restriction due to concerns for exertion-triggered arrhythmia and su… | JACC. Case reports 2026-07-18 15:48:44 | Source |
| Efficacy of perifracture site injections for pain control following d… GenPHSat injection (Efficacy) · PMID 42469861 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source Surgical site analgesic injections are used as part of multimodal analgesia in elective orthopedic surgery, but their e… | Journal of orthopaedic surgery and research 2026-07-18 15:48:08 | Source |
| Denecimig (Mim8) prophylaxis once-every-2-weeks for hemophilia A with… GenPHSat injection (Safety) · PMID 42469164 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Denecimig (Mim8) is a next-generation, activated factor VIII mimetic, fully human bispecific IgG4 antibody in developme… | Blood advances 2026-07-18 15:48:07 | Source |
| Long-term efficacy and safety of intra-articular corticosteroid injec… GenPHSat injection (Safety) · PMID 42470097 | Myopathies | Ralentissement de la progression · Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Knee osteoarthritis (KOA) is a highly prevalent condition worldwide, resulting in a significant symptom burden and dimi… | Expert opinion on drug safety 2026-07-18 15:48:07 | Source |
| Examining the feasibility and preliminary effects of resistance exerc… Creatine Monohydrate · PMID 42455839 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source The purpose of this trial was to assess the feasibility, acceptability and safety of a 10-week hybrid (in-clinic and vi… | PloS one 2026-07-18 15:48:05 | Source |
| A case report of Good syndrome: Diarrhea and dyspnea. IvIg · PMID 42470030 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Good syndrome (GS) is a rare acquired immunodeficiency disorder characterized by thymoma, hypogammaglobulinemia, and pe… | Medicine 2026-07-18 15:47:59 | Source |
| Knowledge graph visualization and bibliometric analysis of research o… IvIg · PMID 42470076 | Myopathies | Thérapie génique | Publication | PubMed | Voir la publication source Coronary artery lesions (CAL) complicating Kawasaki disease (KD) are a central concern affecting the long-term cardiova… | Medicine 2026-07-18 15:47:59 | Source |
| Evaluation of the "Los Filabres" Protocol on Behavioral and Psycholog… Behavioral Interventions for Controlling Oral Behaviors · PMID 42450944 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source Behavioral and psychological symptoms of dementia (BPSD) are highly prevalent among nursing home residents and represen… | Healthcare (Basel, Switzerland) 2026-07-18 15:47:58 | Source |
| Linguistical and psychometric validation of the MIND Youth Questionna… Behavioral Interventions for Controlling Oral Behaviors · PMID 42449006 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source The Mind Youth Questionnaire is a multidimensional health-related quality-of-life questionnaire designed for pediatric… | Journal of patient-reported outcomes 2026-07-18 15:47:58 | Source |
| Adrenal rather than central dysfunction limits HPA axis recovery afte… Chronic Corticosteroid Therapy · PMID 42464759 | Myopathies | Thérapie génique | Publication | PubMed | Voir la publication source Glucocorticoid-induced adrenal insufficiency (GIAI) can persist for months after discontinuation of chronic corticoster… | Endocrinology 2026-07-18 15:47:55 | Source |
| Erectile dysfunction severity and penile Doppler findings in pelvic f… Tadalafil · PMID 42465782 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Erectile dysfunction (ED) is a common and multifactorial complication after pelvic fracture urethral injury (PFUI), yet… | Indian journal of urology : IJU : journal of the Urolo… 2026-07-18 15:47:51 | Source |
| Targeting canonical TGFβ/SMAD3 and ERK1/2 signaling in human valve in… Tadalafil · PMID 42461450 | Myopathies | Ralentissement de la progression · Immunomodulation | Publication | PubMed | Voir la publication source Rheumatic heart disease (RHD) is a chronic sequel of acute rheumatic fever characterized by sustained inflammation, fib… | Journal of physiology and biochemistry 2026-07-18 15:47:51 | Source |
Exploration — prudence
Pistes exploratoires 6
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| N-PPG N-PPG — modulation métabolique cérébrale | Myopathies | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation métabolique et mitohormèse N-PPG est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être pertinents pour Myopat… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |
| Vecteur Ple389 (ADORA2A) MiniPromoter Ple389 — ciblage striatal | Myopathies | Thérapie génique | Hypothèse exploratoire | Rapprochement automatique non validé | Expression génique ciblée dans les neurones striataux Vecteur Ple389 (ADORA2A) est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être per… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |
| α-Amyrin α-Amyrin — protection mitochondriale | Myopathies | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Protection mitochondriale et modulation de la pathologie Tau α-Amyrin est étudié dans Maladie d’Alzheimer et documente plusieurs axes biologiques pouvant être pertinents pour Myopa… | Rapprochement Biomedical Watch · Maladie d’Alzheimer | Détail |
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Myopathies | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation immunométabolique de la microglie 4-octyl itaconate et dérivés est étudié dans Sclérose latérale amyotrophique et documente plusieurs axes biologiques po… | Rapprochement Biomedical Watch · Sclérose latérale amy… | Détail |
| Thonningianin A Thonningianin A — neuroprotection anti-amyloïde | Myopathies | Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation du stress oxydatif et des protéines associées à Alzheimer Thonningianin A est étudié dans Maladie d’Alzheimer et documente plusieurs axes biologiques pouvant être pertinents pou… | Rapprochement Biomedical Watch · Maladie d’Alzheimer | Détail |
| Vutiglabridin Vutiglabridin — autophagie et PON2 | Myopathies | Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Activation de PON2 et stimulation de l’autophagie Vutiglabridin est étudié dans Maladie d’Alzheimer et documente plusieurs axes biologiques pouvant être pertinents pour… | Rapprochement Biomedical Watch · Maladie d’Alzheimer | Détail |