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10635 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 5743
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Cryotherapy NCT03492424 · Ablative Therapy in the Management of Prostate Cancer | Cancer | Immunomodulation | À vérifier | RECRUITING | Background: In published studies, complete response (CR) to chemoradiation… À vérifier | ClinicalTrials.gov 2026-10-25 04:36:54 | Détail |
| ExAblate 2100; InSightec NCT01522118 · MR-guided Focused Ultrasound Treatment of Prostate Cancer: Focal Therapy for Loc… | Cancer | À vérifier | Phase 1 | COMPLETED | Since prostate specific antigen (PSA) was introduced as a clinical screeni… À vérifier | ClinicalTrials.gov 2026-10-25 04:36:54 | Détail |
| high-intensity focused ultrasound ablation NCT00030277 · High-Intensity Focused Ultrasound in Treating Patients With Locally Recurrent Pr… | Cancer | À vérifier | Phase 1 | COMPLETED | RATIONALE: Ultrasound therapy kills tumor cells by heating them to several… À vérifier | ClinicalTrials.gov 2026-10-25 04:36:54 | Détail |
| Hybrid Argon Plasma Coagulation and EMR procedure NCT04015765 · h-APC_EMR — Hybrid-APC Margin Ablation to Prevent Post EMR Adenoma Recurrence | Cancer | À vérifier | Non applicable | COMPLETED | Endoscopic Mucosal Resection (EMR) is the current standard for effective e… À vérifier | ClinicalTrials.gov 2026-10-25 04:36:54 | Détail |
| Local ablative therapy (LAT) NCT06356779 · OLIGO-DK — Longitudinal Study of Local Ablative Therapy in Oligometastatic Disea… | Cancer | À vérifier | Non applicable | RECRUITING | This prospective national multicenter observational and interventional stu… À vérifier | ClinicalTrials.gov 2026-10-25 04:36:54 | Détail |
| MTT(Multimodal Tumor Thermal Therapy System)- Colorectal Cancer NCT06889610 · A Phase II Clinical Study of Multimodal Ablation Combined With Systemic Drug The… | Cancer | À vérifier | Phase 2 | RECRUITING | This study focuses on the treatment of liver metastases from three common… À vérifier | ClinicalTrials.gov 2026-10-25 04:36:54 | Détail |
| pembrolizumab or nivolumab or JS001 NCT03939975 · Anti-PD-1therapy Combined With Thermal Ablation for Advanced HCC | Cancer | À vérifier | Phase 2 | COMPLETED | The inhibition of programmed cell death protein 1 (PD-1) has shown promisi… À vérifier | ClinicalTrials.gov 2026-10-25 04:36:54 | Détail |
| Stereotactic body radiotherapy NCT04081168 · COLLISION-XL — COLLISION XL: Unresectable Colorectal Liver Metastases (3-5cm): S… | Cancer | À vérifier | Non applicable | UNKNOWN | The primary objective of this phase IIb/III, prospective, randomized clini… À vérifier | ClinicalTrials.gov 2026-10-25 04:36:54 | Détail |
| Thermal ablation NCT03864211 · Thermal Ablation Followed by Immunotherapy for HCC | Cancer | À vérifier | Phase 1/2 | UNKNOWN | The primary objective is to prove non-inferiority of thermal ablation comp… À vérifier | ClinicalTrials.gov 2026-10-25 04:36:54 | Détail |
| ultiparametric Magnetic Resonance Imaging NCT06024772 · Multiparametric Ultrasound for the Diagnosis of Clinically Significant Prostate… | Cancer | Thérapie génique | Phase 3 | NOT_YET_RECRUITING | This phase III trial compares the use of contrast-enhanced multiparametric… À vérifier | ClinicalTrials.gov 2026-10-25 04:36:54 | Détail |
| Visualase Thermal Therapy NCT01792024 · MR-Guided Laser Interstitial Thermal Therapy in Treating Patients With Prostate… | Cancer | À vérifier | Non applicable | COMPLETED | This phase II trial studies how well magnetic resonance (MR)-guided laser… À vérifier | ClinicalTrials.gov 2026-10-25 04:36:54 | Détail |
| Robot-Assisted Laparoscopic Surgery NCT02370342 · Robot-Assisted Ultrasound for Thermal Ablative Therapy in Treating Patients With… | Cancer | À vérifier | Non applicable | WITHDRAWN | This clinical trial studies a type of ultrasound called robot-assisted lap… À vérifier | ClinicalTrials.gov 2026-10-25 04:36:53 | Détail |
| aldesleukin NCT06904066 · Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Partic… | Cancer | Immunomodulation · Thérapie génique | Phase 1 | RECRUITING | Background: Blood cancers (such as leukemias) can be hard to treat, especi… À vérifier | ClinicalTrials.gov 2026-10-25 04:36:52 | Détail |
| Biospecimen Collection NCT07097142 · Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in… | Cancer | Traitement symptomatique | Phase 3 | RECRUITING | This phase III trial compares standard of care hormone therapy plus riboci… À vérifier | ClinicalTrials.gov 2026-10-25 04:36:52 | Détail |
| Denosumab (reduced dosing) NCT02051218 · Prevention of Symptomatic Skeletal Events With Denosumab Administered Every 4 We… | Cancer | Traitement symptomatique | Phase 3 | TERMINATED | The aim of the trial is to test the hypothesis that the benefit of denosum… À vérifier | ClinicalTrials.gov 2026-10-25 04:36:52 | Détail |
| MRI NCT02798796 · BREAST-MRI — Brazilian Randomized Study - Impact of MRI for Breast Cancer | Cancer | Remyélinisation · Thérapie génique | Non applicable | COMPLETED | The cognitive disorders of adult forms of myotonic dystrophies type 1 are… À vérifier | ClinicalTrials.gov 2026-10-25 04:36:52 | Détail |
| VS-7375 NCT07659782 · TARGET-D 202 — A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Non… | Cancer | À vérifier | Phase 2 | RECRUITING | This study will assess the safety and efficacy of VS-7375 alone and in com… À vérifier | ClinicalTrials.gov 2026-10-25 04:36:52 | Détail |
| Acalabrutinib (ACP-196) NCT02970318 · A Study of Acalabrutinib vs Investigator's Choice of Idelalisib Plus Rituximab o… | Cancer | À vérifier | Phase 3 | ACTIVE_NOT_RECRUITING | This study is designed to evaluate the efficacy of acalabrutinib compared… À vérifier | ClinicalTrials.gov 2026-10-25 04:36:51 | Détail |
| Bevacizumab NCT07198074 · Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Ca… | Cancer | À vérifier | Phase 3 | RECRUITING | This randomized phase II trial studies how well paclitaxel with or without… À vérifier | ClinicalTrials.gov 2026-10-25 04:36:51 | Détail |
| INR731 NCT07570979 · A Study to Investigate the Safety and Tolerability of Oral INR731 Single Agent o… | Cancer | À vérifier | Phase 1 | RECRUITING | The purpose of this study is to assess the safety, tolerability, pharmacok… À vérifier | ClinicalTrials.gov 2026-10-25 04:36:51 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4871
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Effects of continuous vs. intermittent transcutaneous electrical stim… Transcutaneous electrical nerve stimulation unit (TENS) · PMID 41866984 | Maladie rénale chronique | Traitement symptomatique | Publication | PubMed | Voir la publication source To compare the effects of two transcutaneous electrical stimulation (TES) patterns applied to the auricular branches of… | Cranio : the journal of craniomandibular practice 2026-11-08 04:38:07 | Source |
| Optimizing Percutaneous Tibial Nerve Stimulation Intensity for Overac… Transcutaneous electrical nerve stimulation unit (TENS) · PMID 42554545 | Maladie rénale chronique | Traitement symptomatique | Publication | PubMed | Voir la publication source Overactive bladder (OAB) is a significant global health issue. The standard percutaneous tibial nerve stimulation (PTNS… | Neuromodulation : journal of the International Neuromo… 2026-11-08 04:38:07 | Source |
| Transcutaneous auricular vagus nerve stimulation improves dysautonomi… Transcutaneous electrical nerve stimulation unit (TENS) · PMID 42802247 | Maladie rénale chronique | Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source Autonomic nervous system dysfunction is highly prevalent in hypermobile Ehlers-Danlos syndrome (hEDS) and contributes s… | Neurological sciences : official journal of the Italia… 2026-11-08 04:38:07 | Source |
| Factors associated with high-flow therapy failure in COVID-19-related… Non-Invasive Positive Pressure Ventilation · PMID 42888091 | Maladie rénale chronique | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source The optimal selection of non-invasive respiratory support for patients with COVID-19-related acute hypoxemic respirator… | Enfermedades infecciosas y microbiologia clinica (Engl… 2026-11-08 04:38:06 | Source |
| High-Flow Nasal Cannula in Adult Acute Care: Physiological Mechanisms… Non-Invasive Positive Pressure Ventilation · PMID 42942512 | Maladie rénale chronique | À vérifier | Publication | PubMed | Voir la publication source High-flow nasal cannula (HFNC) oxygen therapy is widely used in emergency, intensive care, perioperative, and procedura… | Medicina (Kaunas, Lithuania) 2026-11-08 04:38:06 | Source |
| Impact of respiratory support on time to achieve full oral feeding in… Non-Invasive Positive Pressure Ventilation · PMID 42871336 | Maladie rénale chronique | À vérifier | Publication | PubMed | Voir la publication source Very low birth weight infants often require respiratory support, which may delay full oral feeding. The independent rol… | Frontiers in pediatrics 2026-11-08 04:38:06 | Source |
| A comparative analysis of 3MAX aspiration versus 3 mm Trevo Retriever… Thromboaspiration catheter · PMID 31243066 | Accident vasculaire cérébral | À vérifier | Publication | PubMed | Voir la publication source Although aspiration and stent retriever thrombectomy perform similarly in proximal occlusions, no comparative series ar… | Journal of neurointerventional surgery 2026-11-08 04:38:02 | Source |
| Percutaneous Pulmonary Thrombectomy Beyond Acute Pulmonary Embolism:… Thromboaspiration catheter · PMID 38385241 | Accident vasculaire cérébral | Thérapie génique | Publication | PubMed | Voir la publication source Subacute massive pulmonary embolism is an uncommon manifestation of severe pulmonary embolism associated with poor prog… | Journal of endovascular therapy : an official journal… 2026-11-08 04:38:02 | Source |
| Simplified classification of cavernous internal carotid artery tortuo… Thromboaspiration catheter · PMID 35475775 | Hypertension artérielle · Accident vasculaire cérébral | Thérapie génique | Publication | PubMed | Voir la publication source Thromboaspiration catheters are increasingly used for the endovascular treatment of large vessel stroke (LVS), while to… | Neurological research 2026-11-08 04:38:02 | Source |
| Multifocal continuous theta burst stimulation in idiopathic generaliz… Continuous Theta Burst Stimulation (cTBS) · PMID 42731195 | Accident vasculaire cérébral | Traitement symptomatique | Publication | PubMed | Voir la publication source Idiopathic generalized epilepsy (IGE) is a disorder of the cortico-subcortical networks. Continuous theta burst stimula… | Clinical neurophysiology : official journal of the Int… 2026-11-08 04:38:00 | Source |
| Optimizing brain functional-structural architecture with cTBS to redu… Continuous Theta Burst Stimulation (cTBS) · PMID 42457860 | Accident vasculaire cérébral | À vérifier | Publication | PubMed | Voir la publication source Alcohol use disorder (AUD) is characterized by high relapse rates, necessitating novel interventions. Continuous theta-… | Molecular psychiatry 2026-11-08 04:38:00 | Source |
| Digital Outreach to Improve Statin Refills in Patients With Low Stati… Cordio System · PMID 42667613 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Statin nonadherence is a leading, addressable driver of preventable cardiovascular events. Although health systems rout… | JAMA 2026-11-08 04:37:54 | Source |
| Endovascular ablation of the right greater splanchnic nerve for the m… Right Greater Splanchnic Nerve (GSN) ablation · PMID 42257781 | Insuffisance cardiaque | Traitement symptomatique | Publication | PubMed | Voir la publication source Heart failure with preserved ejection fraction (HFpEF) remains difficult to manage because conventional therapies often… | The Egyptian heart journal : (EHJ) : official bulletin… 2026-11-08 04:37:54 | Source |
| Incidence, medical therapy, and outcomes in heart failure with improv… Cordio System · PMID 42702264 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source To assess the incidence of heart failure with improved ejection fraction (HFimpEF) across guideline definitions (ACC/AH… | American heart journal 2026-11-08 04:37:54 | Source |
| Relationship Between the Azygos Vein and the Greater Splanchnic Nerve… Right Greater Splanchnic Nerve (GSN) ablation · PMID 42249803 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Although ablation of the greater splanchnic nerve is now being used to treat some patients with heart failure, the anat… | Clinical anatomy (New York, N.Y.) 2026-11-08 04:37:54 | Source |
| Validation of the PREVENT-HF Risk Prediction Equation in US Veterans. Cordio System · PMID 42969140 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Résumé non disponible dans la base locale. | Circulation 2026-11-08 04:37:54 | Source |
| Changes in right ventricular-pulmonary artery coupling after transcat… Tricuspid Transcatheter Edge-to-Edge Repair (TEER) · PMID 42822601 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Right ventricular-pulmonary artery (RV-PA) coupling is an established marker of prognosis in mitral regurgitation (MR),… | International journal of cardiology 2026-11-08 04:37:47 | Source |
| Intraprocedural evaluation of residual mitral and tricuspid regurgita… Tricuspid Transcatheter Edge-to-Edge Repair (TEER) · PMID 42982241 | Maladie coronarienne | À vérifier | Publication | PubMed | Voir la publication source Transcatheter edge-to-edge repair (TEER) has emerged as an established therapeutic option for selected patients with se… | International journal of cardiology 2026-11-08 04:37:47 | Source |
| Tricuspid transcatheter edge-to-edge repair versus transcatheter tric… Tricuspid Transcatheter Edge-to-Edge Repair (TEER) · PMID 42989943 | Maladie coronarienne | À vérifier | Publication | PubMed | Voir la publication source Recent clinical studies of tricuspid transcatheter edge-to-edge repair (T-TEER) and transcatheter tricuspid valve repla… | Current opinion in cardiology 2026-11-08 04:37:47 | Source |
| Automated Production of Gene-Edited CAR-T Cells for People Living wit… RAPA-501 Autologous T stem cells · PMID 42847201 | Cancer | Thérapie cellulaire · Thérapie génique | Publication | PubMed | Voir la publication source Adoptive transfer of gene-modified autologous T cells, for example, expressing chimeric antigen receptors (CARs), is a… | Human gene therapy 2026-11-08 04:37:39 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||