Vue transversale globale
Toutes les maladies
Un même point d’entrée pour les études cliniques, les découvertes scientifiques, les publications et les pistes exploratoires présentes dans Biomedical Watch.
Périmètre
Filtrer toute la vue
Chaque choix s’applique immédiatement aux quatre sections. Le filtre « type de SEP » n’apparaît que lorsque la sclérose en plaques est sélectionnée.
10635 résultats correspondants
· 41 visibles sur cette page
dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 5743
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| RAD001 NCT01713946 · A Placebo-controlled Study of Efficacy & Safety of 2 Trough-ranges of Everolimus… | Épilepsie | À vérifier | Phase 3 | COMPLETED | This study evaluated the efficacy and safety of two trough-ranges of evero… À vérifier | ClinicalTrials.gov 2026-07-08 15:42:27 | Détail |
| Self-management for People With Epilepsy and a History of Negative He… NCT02970396 · NCT02970396 | Épilepsie | À vérifier | NA | COMPLETED | This is an investigation of adult individuals with epilepsy, and involves… À vérifier | ClinicalTrials.gov 2026-07-08 15:42:27 | Détail |
| Active vibrotactile coordinated reset NCT05881460 · Vibrotactile Coordinated Reset: A Non-invasive Treatment for Parkinson's Disease… | Maladie de Parkinson | Thérapie génique | NA | ACTIVE_NOT_RECRUITING | The purpose of our study is to evaluate Vibrotactile Coordinated Reset sti… À vérifier | ClinicalTrials.gov 2026-07-08 15:42:26 | Détail |
| Changes in Movement, Fitness, and Quality of Life in People With Park… NCT07221266 · NCT07221266 | Maladie de Parkinson | Neuroprotection · Immunomodulation | NA | RECRUITING | Parkinson's disease (PD) is a progressive neurological condition that can… À vérifier | ClinicalTrials.gov 2026-07-08 15:42:26 | Détail |
| CVN424 75 mg NCT06553027 · To Evaluate the Efficacy of CVN424 in Parkinson's Disease Participants With Moto… | Maladie de Parkinson | À vérifier | Phase 3 | ACTIVE_NOT_RECRUITING | This is a randomized, double-blind, placebo-controlled, multicenter study… À vérifier | ClinicalTrials.gov 2026-07-08 15:42:26 | Détail |
| Digital GaitCare - Therapy Monitoring in the Home Environment of Pati… NCT04931303 · NCT04931303 | Maladie de Parkinson | Ralentissement de la progression · Traitement symptomatique | À vérifier | COMPLETED | Gait disturbances and movement restrictions occur frequently in Parkinson'… À vérifier | ClinicalTrials.gov 2026-07-08 15:42:26 | Détail |
| Evaluation of Advanced Imaging and Visualization for Clinical Deep Br… NCT06191874 · NCT06191874 | Maladie de Parkinson | À vérifier | À vérifier | COMPLETED | The objective of this project is to evaluate next generation visualization… À vérifier | ClinicalTrials.gov 2026-07-08 15:42:26 | Détail |
| Ginseng NCT01712373 · Ginseng in Treatment of Fatigue in Multiple Sclerosis | Sclérose en plaques | Traitement symptomatique | Phase 2 | COMPLETED | The purpose of this study was to evaluate the efficacy and safety of Ginse… À vérifier | ClinicalTrials.gov 2026-07-08 15:42:26 | Détail |
| GNbAC1 NCT03179423 · RAINBOW-T1D — Clinical Trial Assessing the GNbAC1 in Patients With Onset of Type… | Sclérose en plaques | À vérifier | Phase 2 | COMPLETED | The monoclonal antibody GNbAC1 targets the envelope protein (Env) of the h… À vérifier | ClinicalTrials.gov 2026-07-08 15:42:26 | Détail |
| Risk Factors in Early Multiple Sclerosis NCT03586986 · NCT03586986 | Sclérose en plaques | Neuroprotection · Traitement symptomatique | À vérifier | UNKNOWN | The central hypothesis of this protocol is that it is possible, using Firs… À vérifier | ClinicalTrials.gov 2026-07-08 15:42:26 | Détail |
| Systematic exercise training NCT03322761 · Early Exercise Efforts in Multiple Sclerosis | Sclérose en plaques | Ralentissement de la progression · Traitement symptomatique | NA | COMPLETED | This study seeks to investigate whether early exercise efforts can expand… À vérifier | ClinicalTrials.gov 2026-07-08 15:42:26 | Détail |
| Zeposia NCT04885894 · An Examination of Cognitive Fatigue Using Functional Neuroimaging | Sclérose en plaques | Traitement symptomatique | À vérifier | UNKNOWN | The purpose of this research study is to investigate the effectiveness of… À vérifier | ClinicalTrials.gov 2026-07-08 15:42:26 | Détail |
| ALS patients genetic characterization NCT03073239 · Amyotrophic Lateral Sclerosis: a New Paradigm | Sclérose latérale amyotrophique | À vérifier | À vérifier | COMPLETED | Description non affichée : incohérence de maladie détectée. Consultez l’es… À vérifier | ClinicalTrials.gov 2026-07-08 12:06:28 | Détail |
| COVID-19 Pandemic and Parents of Disabled Children NCT04525742 · NCT04525742 | Myopathies | À vérifier | NA | COMPLETED | Pandemic period could affect the disabled children's rehabilitation and fo… À vérifier | ClinicalTrials.gov 2026-07-08 12:06:28 | Détail |
| Custom Mask Interface NCT03519880 · A Pilot Study of the Utility of 3D Printed Masks for ALS Subjects | Sclérose latérale amyotrophique | À vérifier | NA | TERMINATED | Description non affichée : incohérence de maladie détectée. Consultez l’es… À vérifier | ClinicalTrials.gov 2026-07-08 12:06:28 | Détail |
| DAS-001 NCT04226170 · Study of Pyridostigmine With Ondansetron in Subjects With Anti-AchR Positive Mya… | Myasthénie | À vérifier | Phase 2 | TERMINATED | This is a phase II, single center, randomized, double-blind, placebo-contr… À vérifier | ClinicalTrials.gov 2026-07-08 12:06:28 | Détail |
| eculizumab NCT00727194 · Safety and Efficacy Study of Eculizumab in Patients With Refractory Generalized… | Myasthénie | À vérifier | Phase 2 | TERMINATED | The purpose of this study is to determine whether eculizumab is safe and e… À vérifier | ClinicalTrials.gov 2026-07-08 12:06:28 | Détail |
| EDG-5506 Tablet NCT05730842 · Absorption, Metabolism, Excretion and Absolute Bioavailability of EDG-5506 in He… | Myopathies | À vérifier | Phase 1 | COMPLETED | This is a Phase 1 2-part, single-center, open-label study in healthy male… À vérifier | ClinicalTrials.gov 2026-07-08 12:06:28 | Détail |
| Inspiratory muscle training NCT06624345 · Interval Inspiratory Training and Aerobic Exercise for Muscle Recovery in Myasth… | Myasthénie | À vérifier | NA | COMPLETED | The goal of this clinical trial is to determine whether inspiratory muscle… À vérifier | ClinicalTrials.gov 2026-07-08 12:06:28 | Détail |
| MRI NCT04656210 · Myotonic Dystrophy - Vascular and Cognition | Myopathies | Remyélinisation · Thérapie génique | À vérifier | ACTIVE_NOT_RECRUITING | The cognitive disorders of adult forms of myotonic dystrophies type 1 are… À vérifier | ClinicalTrials.gov 2026-07-08 12:06:28 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4871
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Effects of continuous vs. intermittent transcutaneous electrical stim… Transcutaneous electrical nerve stimulation unit (TENS) · PMID 41866984 | Maladie rénale chronique | Traitement symptomatique | Publication | PubMed | Voir la publication source To compare the effects of two transcutaneous electrical stimulation (TES) patterns applied to the auricular branches of… | Cranio : the journal of craniomandibular practice 2026-11-08 04:38:07 | Source |
| Optimizing Percutaneous Tibial Nerve Stimulation Intensity for Overac… Transcutaneous electrical nerve stimulation unit (TENS) · PMID 42554545 | Maladie rénale chronique | Traitement symptomatique | Publication | PubMed | Voir la publication source Overactive bladder (OAB) is a significant global health issue. The standard percutaneous tibial nerve stimulation (PTNS… | Neuromodulation : journal of the International Neuromo… 2026-11-08 04:38:07 | Source |
| Transcutaneous auricular vagus nerve stimulation improves dysautonomi… Transcutaneous electrical nerve stimulation unit (TENS) · PMID 42802247 | Maladie rénale chronique | Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source Autonomic nervous system dysfunction is highly prevalent in hypermobile Ehlers-Danlos syndrome (hEDS) and contributes s… | Neurological sciences : official journal of the Italia… 2026-11-08 04:38:07 | Source |
| Factors associated with high-flow therapy failure in COVID-19-related… Non-Invasive Positive Pressure Ventilation · PMID 42888091 | Maladie rénale chronique | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source The optimal selection of non-invasive respiratory support for patients with COVID-19-related acute hypoxemic respirator… | Enfermedades infecciosas y microbiologia clinica (Engl… 2026-11-08 04:38:06 | Source |
| High-Flow Nasal Cannula in Adult Acute Care: Physiological Mechanisms… Non-Invasive Positive Pressure Ventilation · PMID 42942512 | Maladie rénale chronique | À vérifier | Publication | PubMed | Voir la publication source High-flow nasal cannula (HFNC) oxygen therapy is widely used in emergency, intensive care, perioperative, and procedura… | Medicina (Kaunas, Lithuania) 2026-11-08 04:38:06 | Source |
| Impact of respiratory support on time to achieve full oral feeding in… Non-Invasive Positive Pressure Ventilation · PMID 42871336 | Maladie rénale chronique | À vérifier | Publication | PubMed | Voir la publication source Very low birth weight infants often require respiratory support, which may delay full oral feeding. The independent rol… | Frontiers in pediatrics 2026-11-08 04:38:06 | Source |
| A comparative analysis of 3MAX aspiration versus 3 mm Trevo Retriever… Thromboaspiration catheter · PMID 31243066 | Accident vasculaire cérébral | À vérifier | Publication | PubMed | Voir la publication source Although aspiration and stent retriever thrombectomy perform similarly in proximal occlusions, no comparative series ar… | Journal of neurointerventional surgery 2026-11-08 04:38:02 | Source |
| Percutaneous Pulmonary Thrombectomy Beyond Acute Pulmonary Embolism:… Thromboaspiration catheter · PMID 38385241 | Accident vasculaire cérébral | Thérapie génique | Publication | PubMed | Voir la publication source Subacute massive pulmonary embolism is an uncommon manifestation of severe pulmonary embolism associated with poor prog… | Journal of endovascular therapy : an official journal… 2026-11-08 04:38:02 | Source |
| Simplified classification of cavernous internal carotid artery tortuo… Thromboaspiration catheter · PMID 35475775 | Hypertension artérielle · Accident vasculaire cérébral | Thérapie génique | Publication | PubMed | Voir la publication source Thromboaspiration catheters are increasingly used for the endovascular treatment of large vessel stroke (LVS), while to… | Neurological research 2026-11-08 04:38:02 | Source |
| Multifocal continuous theta burst stimulation in idiopathic generaliz… Continuous Theta Burst Stimulation (cTBS) · PMID 42731195 | Accident vasculaire cérébral | Traitement symptomatique | Publication | PubMed | Voir la publication source Idiopathic generalized epilepsy (IGE) is a disorder of the cortico-subcortical networks. Continuous theta burst stimula… | Clinical neurophysiology : official journal of the Int… 2026-11-08 04:38:00 | Source |
| Optimizing brain functional-structural architecture with cTBS to redu… Continuous Theta Burst Stimulation (cTBS) · PMID 42457860 | Accident vasculaire cérébral | À vérifier | Publication | PubMed | Voir la publication source Alcohol use disorder (AUD) is characterized by high relapse rates, necessitating novel interventions. Continuous theta-… | Molecular psychiatry 2026-11-08 04:38:00 | Source |
| Digital Outreach to Improve Statin Refills in Patients With Low Stati… Cordio System · PMID 42667613 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Statin nonadherence is a leading, addressable driver of preventable cardiovascular events. Although health systems rout… | JAMA 2026-11-08 04:37:54 | Source |
| Endovascular ablation of the right greater splanchnic nerve for the m… Right Greater Splanchnic Nerve (GSN) ablation · PMID 42257781 | Insuffisance cardiaque | Traitement symptomatique | Publication | PubMed | Voir la publication source Heart failure with preserved ejection fraction (HFpEF) remains difficult to manage because conventional therapies often… | The Egyptian heart journal : (EHJ) : official bulletin… 2026-11-08 04:37:54 | Source |
| Incidence, medical therapy, and outcomes in heart failure with improv… Cordio System · PMID 42702264 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source To assess the incidence of heart failure with improved ejection fraction (HFimpEF) across guideline definitions (ACC/AH… | American heart journal 2026-11-08 04:37:54 | Source |
| Relationship Between the Azygos Vein and the Greater Splanchnic Nerve… Right Greater Splanchnic Nerve (GSN) ablation · PMID 42249803 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Although ablation of the greater splanchnic nerve is now being used to treat some patients with heart failure, the anat… | Clinical anatomy (New York, N.Y.) 2026-11-08 04:37:54 | Source |
| Validation of the PREVENT-HF Risk Prediction Equation in US Veterans. Cordio System · PMID 42969140 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Résumé non disponible dans la base locale. | Circulation 2026-11-08 04:37:54 | Source |
| Changes in right ventricular-pulmonary artery coupling after transcat… Tricuspid Transcatheter Edge-to-Edge Repair (TEER) · PMID 42822601 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Right ventricular-pulmonary artery (RV-PA) coupling is an established marker of prognosis in mitral regurgitation (MR),… | International journal of cardiology 2026-11-08 04:37:47 | Source |
| Intraprocedural evaluation of residual mitral and tricuspid regurgita… Tricuspid Transcatheter Edge-to-Edge Repair (TEER) · PMID 42982241 | Maladie coronarienne | À vérifier | Publication | PubMed | Voir la publication source Transcatheter edge-to-edge repair (TEER) has emerged as an established therapeutic option for selected patients with se… | International journal of cardiology 2026-11-08 04:37:47 | Source |
| Tricuspid transcatheter edge-to-edge repair versus transcatheter tric… Tricuspid Transcatheter Edge-to-Edge Repair (TEER) · PMID 42989943 | Maladie coronarienne | À vérifier | Publication | PubMed | Voir la publication source Recent clinical studies of tricuspid transcatheter edge-to-edge repair (T-TEER) and transcatheter tricuspid valve repla… | Current opinion in cardiology 2026-11-08 04:37:47 | Source |
| Automated Production of Gene-Edited CAR-T Cells for People Living wit… RAPA-501 Autologous T stem cells · PMID 42847201 | Cancer | Thérapie cellulaire · Thérapie génique | Publication | PubMed | Voir la publication source Adoptive transfer of gene-modified autologous T cells, for example, expressing chimeric antigen receptors (CARs), is a… | Human gene therapy 2026-11-08 04:37:39 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||