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Toutes les maladies
Un même point d’entrée pour les études cliniques, les découvertes scientifiques, les publications et les pistes exploratoires présentes dans Biomedical Watch.
Périmètre
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8666 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 4050
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Doxorubicin Hydrochloride Étude non communiquée | Cancer · Sclérose en plaques | À vérifier | Phase 2 | Arrêté / suspendu | This randomized phase II trial studies how well paclitaxel with or without… À vérifier | ClinicalTrials.gov 2021-10-19 | Détail |
| EPOCH regimen Étude non communiquée | Sclérose en plaques | À vérifier | Phase 2 | Arrêté / suspendu | RATIONALE: Monoclonal antibodies such as rituximab can locate cancer cells… À vérifier | ClinicalTrials.gov 2021-10-19 | Détail |
| Etoposide Étude non communiquée | Cancer · Myasthénie · Maladie de Parkinson · Sclérose en plaques | À vérifier | Phase 2 | Arrêté / suspendu | The purpose of this study is to evaluate the use of investigational agents… À vérifier | ClinicalTrials.gov 2021-10-19 | Détail |
| Sargramostim Étude non communiquée | Cancer · Sclérose en plaques | Immunomodulation | Phase 2 | Arrêté / suspendu | This phase I trial studies the side effects of survivin long peptide vacci… À vérifier | ClinicalTrials.gov 2021-10-19 | Détail |
| Opioid Anesthetics Étude non communiquée | Cancer | À vérifier | Phase 1 | Terminé | Hemodynamic control during craniotomies can be a bit hectic specially duri… À vérifier | ClinicalTrials.gov 2021-10-17 | Détail |
| Levodopa (L-DOPA) + Standard care Étude non communiquée | Maladie de Parkinson | À vérifier | À vérifier | Terminé | The purpose of this study is to describe the safety and efficacy of opicap… À vérifier | ClinicalTrials.gov 2021-10-01 | Détail |
| Part B: TRV250 Dose 1 Étude non communiquée | Migraine | À vérifier | Phase 1 | Échec | A trial to assess the efficacy, safety, tolerability and effect of a drug… À vérifier | ClinicalTrials.gov 2021-09-20 | Détail |
| Part B: TRV250 Dose 2 Étude non communiquée | Migraine | À vérifier | Phase 1 | Échec | A trial to assess the efficacy, safety, tolerability and effect of a drug… À vérifier | ClinicalTrials.gov 2021-09-20 | Détail |
| Part B: TRV250 Dose 3 Étude non communiquée | Migraine | À vérifier | Phase 1 | Échec | A trial to assess the efficacy, safety, tolerability and effect of a drug… À vérifier | ClinicalTrials.gov 2021-09-20 | Détail |
| conventional treatment plan Étude non communiquée | Maladie de Parkinson | À vérifier | NA | Terminé | To compare the effects of exer-gaming with conventional physiotherapy on b… À vérifier | ClinicalTrials.gov 2021-09-13 | Détail |
| Copaxone-Teva Étude non communiquée | Sclérose en plaques | Neuroprotection | Phase 3 | Terminé | The objective of the clinical study of the medicinal product for medical u… À vérifier | ClinicalTrials.gov 2021-09-08 | Détail |
| injectable MS DMT Étude non communiquée | Sclérose en plaques | À vérifier | Phase 4 | Terminé | The primary objective of the study is to determine if dimethyl fumarate (D… À vérifier | ClinicalTrials.gov 2021-09-03 | Détail |
| Landmark-Based Greater Occipital Nerve Block Étude non communiquée | Migraine | À vérifier | Non applicable | Terminé | This study will compare the analgesic benefit of a traditional landmark-gu… À vérifier | ClinicalTrials.gov 2021-06-14 | Détail |
| Sumatriptan Succinate Oral Tablet Étude non communiquée | Sclérose en plaques | À vérifier | Phase 4 | Terminé | Objectives: To compare the safety and efficacy of oral theophylline versus… À vérifier | ClinicalTrials.gov 2021-05-31 | Détail |
| Lumishade® Sham Lens Étude non communiquée | Migraine | Traitement symptomatique | Non applicable | UNKNOWN | This proof of concept clinical study will investigate the efficacy of acti… À vérifier | ClinicalTrials.gov 2021-05-21 | Détail |
| O-15 Water Étude non communiquée | Maladie de Parkinson · Sclérose en plaques | À vérifier | Phase 3 | Terminé | This is an in vivo positron emission tomography (PET) study of regional ce… À vérifier | ClinicalTrials.gov 2021-05-20 | Détail |
| Sham gammaCore/electroCore Étude non communiquée | Sclérose en plaques | Immunomodulation | Phase 3 | Terminé | The tasks of the project are to map the potency and kinetics of the neurol… À vérifier | ClinicalTrials.gov 2021-05-20 | Détail |
| Nerivio Migra-1 Sham device Étude non communiquée | Migraine | Traitement symptomatique | Non applicable | Terminé | Migraine is a common neurologic with attacks of headache and associated sy… À vérifier | ClinicalTrials.gov 2021-05-17 | Détail |
| Acetaminophen Alone Étude non communiquée | Migraine | À vérifier | Phase 2 | Terminé | The study consists of a screening visit, out-patient treatment of a modera… À vérifier | ClinicalTrials.gov 2021-04-11 | Détail |
| Naltrexone Alone (regular dose) Étude non communiquée | Migraine | À vérifier | Phase 2 | Terminé | The study consists of a screening visit, out-patient treatment of a modera… À vérifier | ClinicalTrials.gov 2021-04-11 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4595
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Effects of testosterone-augmented multimodal exercise intervention in… Whole-body Electrical Muscle Stimulation Exercise · PMID 41988780 | Myasthénie | À vérifier | Publication | PubMed | Voir la publication source Spinal cord injury (SCI) leads to profound muscle atrophy, aerobic deconditioning, and metabolic dysfunction. Exercise-… | The Journal of clinical endocrinology and metabolism 2026-09-20 04:37:05 | Source |
| Feasibility and acceptability of whole-body electromyostimulation in… Whole-body Electrical Muscle Stimulation Exercise · PMID 42464389 | Myasthénie | À vérifier | Publication | PubMed | Voir la publication source Evidence on the effectiveness of electromyostimulation (EMS) has been reported in pulmonary rehabilitation, but the ben… | Pilot and feasibility studies 2026-09-20 04:37:05 | Source |
| Vestibular contributions adapt to the balance strategies adopted duri… Whole-body Electrical Muscle Stimulation Exercise · PMID 42616645 | Myasthénie | À vérifier | Publication | PubMed | Voir la publication source Vestibular contributions during walking are not uniform, but vary with gait phase, muscle group, and balance demands. M… | Journal of neurophysiology 2026-09-20 04:37:05 | Source |
| Clinical efficacy of abdominal moxibustion at the Zhongji (CV3) in co… Yangyin Roujin Decoction · PMID 42015783 | Myopathies | Neuroprotection · Traitement symptomatique | Publication | PubMed | Voir la publication source To investigate the clinical effect of abdominal moxibustion at the Zhongji (CV3) combined with Yiqi Tonglin Yangyin dec… | Journal of traditional Chinese medicine = Chung i tsa… 2026-09-20 04:37:03 | Source |
| Yiqi Huoxue Yangyin Decoction Ameliorates Diabetic Nephropathy by Tar… Yangyin Roujin Decoction · PMID 42713045 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source This study aimed to investigate the protective effects and underlying mechanisms of Yiqi Huoxue Yangyin Decoction (YHY)… | Diabetes, metabolic syndrome and obesity : targets and… 2026-09-20 04:37:03 | Source |
| Yiqi Huoxue Yangyin Decoction attenuates diabetic nephropathy in mice… Yangyin Roujin Decoction · PMID 42016924 | Myopathies | Thérapie génique | Publication | PubMed | Voir la publication source Diabetic nephropathy (DN) is a major complication of diabetes with limited therapeutic options. Yiqi Huoxue Yangyin Dec… | Frontiers in pharmacology 2026-09-20 04:37:03 | Source |
| Barcoded oligonucleotide system (BOLT) for targeted organ delivery. Immunotherapy · PMID 42733790 | Cancer | À vérifier | Publication | PubMed | Voir la publication source The therapeutic potential of oligonucleotides (oligos) is limited by insufficient delivery to extrahepatic tissues. In… | Bioactive materials 2026-09-20 04:36:56 | Source |
| Dual metabolic checkpoint blockade a 3D-Printed metalloplatform remod… Immunotherapy · PMID 42724565 | Cancer | Immunomodulation | Publication | PubMed | Voir la publication source The immunosuppressive tumor microenvironment limits the efficacy of therapies that target metabolism. Here we show a st… | Bioactive materials 2026-09-20 04:36:56 | Source |
| Oligosaccharide adjuvant-deferred antigen endocytosis promotes cross-… Immunotherapy · PMID 42751513 | Cancer | Immunomodulation · Thérapie génique | Publication | PubMed | Voir la publication source Antigen cross-presentation by dendritic cells (DCs) is essential for inducing cytotoxic immune responses, which are cru… | Bioactive materials 2026-09-20 04:36:56 | Source |
| Feasibility and safety of early discharge after robot-assisted uro-on… Digital care pathway for hypertension · PMID 42671715 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source Early discharge after robot-assisted uro-oncologic surgery remains limited by concerns regarding patient safety and the… | Journal of robotic surgery 2026-09-20 04:36:49 | Source |
| HomeSafe: Postpartum Hypertensive Care Enabled by Electronic Health R… Digital care pathway for hypertension · PMID 41707683 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source The objective is to present stepwise refinements to , an Epic-tethered, population-health-coordinated postpartum pathwa… | American journal of perinatology 2026-09-20 04:36:49 | Source |
| Nutraceutical and functional food: efficacy against metabolic disorde… Digital care pathway for hypertension · PMID 42603698 | Hypertension artérielle | Neuroprotection · Immunomodulation | Publication | PubMed | Voir la publication source The growing global emphasis on health consciousness has significantly increased demand for traditional and complementar… | Journal of advanced research 2026-09-20 04:36:49 | Source |
| Community-engaged design of a virtual diabetes prevention program int… Asynchronous communication with nurse · PMID 42288862 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source The Diabetes Prevention Program (DPP) is an evidence-based approach to prevent Type 2 Diabetes (T2D), the leading cause… | BMC health services research 2026-09-20 04:36:48 | Source |
| Evolving Lung Cancer Navigator Practice Through Targeted Professional… Asynchronous communication with nurse · PMID 42463006 | Cancer | À vérifier | Publication | PubMed | Voir la publication source Lung cancer remains the leading cause of cancer deaths worldwide, and it has persistent disparities in detection, treat… | Chest 2026-09-20 04:36:48 | Source |
| Mass casualty training for prehospital and emergency providers in Kig… Asynchronous communication with nurse · PMID 42751142 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source A mass casualty incident (MCI) occurs when the number of patients exceeds available healthcare resources, placing signi… | African journal of emergency medicine : Revue africain… 2026-09-20 04:36:48 | Source |
| Innovating a Teach-Back Model for Community Health Workers Led Health… Health Literacy Project · PMID 40194526 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source From 2021 to 2023, the City of Albuquerque, the University of New Mexico (UNM) Office for Community Health, the UNM Hos… | Health literacy research and practice 2026-09-20 04:36:34 | Source |
| Carotid intima-media thickness may be an early biomarker for cardiova… Impact of Ketogenic Diets on Cardiovascular Health in Adults With Epilepsy · PMID 41026111 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source To assess early signs of atherosclerosis following long-term treatment with the ketogenic diet therapy due to concerns… | Epilepsia open 2026-09-20 04:36:33 | Source |
| Impact of low-carbohydrate diet on health status: an umbrella review. Impact of Ketogenic Diets on Cardiovascular Health in Adults With Epilepsy · PMID 39385794 | Cancer | À vérifier | Publication | PubMed | Voir la publication source The prevalence of diet-related non-communicable diseases has increased. A low-carbohydrate diet (LCDs) is one of the mo… | Frontiers in nutrition 2026-09-20 04:36:33 | Source |
| The effect of anti-seizure medications on lipid values in adults with… Impact of Ketogenic Diets on Cardiovascular Health in Adults With Epilepsy · PMID 37244221 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source Certain anti-seizure medications (ASMs) adversely impact lipid values. Here, we explored the impact of ASMs on lipid va… | Epilepsy & behavior : E&B 2026-09-20 04:36:33 | Source |
| Possible role of locus coeruleus neuronal loss in age-related memory… The Role of the Locus Coeruleus in Age-related Distractibility · PMID 37694113 | Maladie d’Alzheimer | Immunomodulation | Publication | PubMed | Voir la publication source Aging is associated with a decline in cognitive abilities, including memory and attention. It is generally accepted tha… | Frontiers in neuroscience 2026-09-20 04:36:30 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||