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Toutes les maladies
Un même point d’entrée pour les études cliniques, les découvertes scientifiques, les publications et les pistes exploratoires présentes dans Biomedical Watch.
Périmètre
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Chaque choix s’applique immédiatement aux quatre sections. Le filtre « type de SEP » n’apparaît que lorsque la sclérose en plaques est sélectionnée.
8666 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 4050
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| standard therapy Étude non communiquée | Lupus | À vérifier | Phase 1 | Terminé | This is a multi-center, open-label, phase I study. À vérifier | ClinicalTrials.gov 2023-12-05 | Détail |
| PACAP-38 Étude non communiquée | Migraine | À vérifier | Non applicable | Terminé | To investigate whether administration of calcitonin gene-related peptide (… À vérifier | ClinicalTrials.gov 2023-11-30 | Détail |
| Tailor-made Notched Music Training Étude non communiquée | Sclérose en plaques | À vérifier | Non applicable | Prévu | This clinical study is a prospective, multicenter, randomized, controlled,… À vérifier | ClinicalTrials.gov 2023-11-22 | Détail |
| Oral Prophylactic Étude non communiquée | Migraine | À vérifier | Phase 4 | Terminé | The purpose of this study is to compare the sustained long-term benefit be… À vérifier | ClinicalTrials.gov 2023-11-01 | Détail |
| Primary major amputation Étude non communiquée | Myopathies | Thérapie génique | À vérifier | Terminé | The primary objective of this study is to evaluate the effect of different… À vérifier | ClinicalTrials.gov 2023-10-30 | Détail |
| Noninvasive transcutaneous auricular vagus nerve stimulation at 25Hz Étude non communiquée | Sclérose en plaques | À vérifier | Non applicable | Terminé | This is a randomised, within-subject, double-blinded, placebo-controlled s… À vérifier | ClinicalTrials.gov 2023-10-15 | Détail |
| Sham cyma conchae stimulation Étude non communiquée | Sclérose en plaques | À vérifier | Non applicable | Terminé | This is a randomised, within-subject, double-blinded, placebo-controlled s… À vérifier | ClinicalTrials.gov 2023-10-15 | Détail |
| CoolStat sham device Étude non communiquée | Migraine | Traitement symptomatique | Non applicable | Arrêté / suspendu | This is a prospective, double-blind, sham-controlled, randomized study to… À vérifier | ClinicalTrials.gov 2023-09-06 | Détail |
| GenPHSat injection (Efficacy) Étude non communiquée | Myopathies | À vérifier | Phase 1 | UNKNOWN | This study is an investigator initiated first-in-human interventional open… À vérifier | ClinicalTrials.gov 2023-08-02 | Détail |
| Amifampridine (base) with modified release Étude non communiquée | Myasthénie | À vérifier | Phase 3 | UNKNOWN | A randomized, double-blind, placebo controlled, crossover intervention stu… À vérifier | ClinicalTrials.gov 2023-06-16 | Détail |
| Glatiramer acetate Étude non communiquée | Sclérose en plaques | Remyélinisation | Phase 2 | Arrêté / suspendu | Primary Objective: To evaluate the efficacy, safety, and tolerability of a… À vérifier | ClinicalTrials.gov 2023-05-31 | Détail |
| Interferon-beta1 Étude non communiquée | Sclérose en plaques | Remyélinisation · Neuroprotection · Ralentissement de la progression | Phase 2 | Arrêté / suspendu | The primary objectives of the study are to evaluate the safety of BIIB061… À vérifier | ClinicalTrials.gov 2023-05-31 | Détail |
| sham iTBS Étude non communiquée | Maladie de Parkinson | À vérifier | Non applicable | UNKNOWN | Intermittent theta burst stimulation (iTBS) is an emerging non-invasive ne… À vérifier | ClinicalTrials.gov 2023-05-08 | Détail |
| Radiolabeled EDG-5506 Intravenous Étude non communiquée | Myopathies | À vérifier | Phase 1 | Terminé | This is a Phase 1 2-part, single-center, open-label study in healthy male… À vérifier | ClinicalTrials.gov 2023-04-14 | Détail |
| Radiolabeled EDG-5506 Suspension Étude non communiquée | Myopathies | À vérifier | Phase 1 | Terminé | This is a Phase 1 2-part, single-center, open-label study in healthy male… À vérifier | ClinicalTrials.gov 2023-04-14 | Détail |
| HBM9161 Injection (340 mg) Étude non communiquée | Myasthénie | À vérifier | Phase 2 | Terminé | Primary Objectives: To investigate the efficacy of HBM9161 in patients wit… À vérifier | ClinicalTrials.gov 2023-03-06 | Détail |
| Carbidopa and Levodopa Controlled Release Tablets Étude non communiquée | Maladie de Parkinson | À vérifier | Phase 4 | UNKNOWN | The main goal of PD research is to develop disease-modifying drugs to dela… À vérifier | ClinicalTrials.gov 2023-02-14 | Détail |
| Continued Ocrelizumab Étude non communiquée | Sclérose en plaques | Ralentissement de la progression · Immunomodulation | Phase 2 | Arrêté / suspendu | Multiple sclerosis is the most common inflammatory disease of the central… À vérifier | ClinicalTrials.gov 2023-02-07 | Détail |
| Short-course Ocrelizumab Étude non communiquée | Sclérose en plaques | Ralentissement de la progression · Immunomodulation | Phase 2 | Arrêté / suspendu | Multiple sclerosis is the most common inflammatory disease of the central… À vérifier | ClinicalTrials.gov 2023-02-07 | Détail |
| ThisCART19A with Dose Level 2 Étude non communiquée | Sclérose en plaques | Thérapie cellulaire | Phase 1 | UNKNOWN | This is a phase 1, single-center, dose selection study to evaluate the eff… À vérifier | ClinicalTrials.gov 2023-01-18 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4595
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Effects of testosterone-augmented multimodal exercise intervention in… Whole-body Electrical Muscle Stimulation Exercise · PMID 41988780 | Myasthénie | À vérifier | Publication | PubMed | Voir la publication source Spinal cord injury (SCI) leads to profound muscle atrophy, aerobic deconditioning, and metabolic dysfunction. Exercise-… | The Journal of clinical endocrinology and metabolism 2026-09-20 04:37:05 | Source |
| Feasibility and acceptability of whole-body electromyostimulation in… Whole-body Electrical Muscle Stimulation Exercise · PMID 42464389 | Myasthénie | À vérifier | Publication | PubMed | Voir la publication source Evidence on the effectiveness of electromyostimulation (EMS) has been reported in pulmonary rehabilitation, but the ben… | Pilot and feasibility studies 2026-09-20 04:37:05 | Source |
| Vestibular contributions adapt to the balance strategies adopted duri… Whole-body Electrical Muscle Stimulation Exercise · PMID 42616645 | Myasthénie | À vérifier | Publication | PubMed | Voir la publication source Vestibular contributions during walking are not uniform, but vary with gait phase, muscle group, and balance demands. M… | Journal of neurophysiology 2026-09-20 04:37:05 | Source |
| Clinical efficacy of abdominal moxibustion at the Zhongji (CV3) in co… Yangyin Roujin Decoction · PMID 42015783 | Myopathies | Neuroprotection · Traitement symptomatique | Publication | PubMed | Voir la publication source To investigate the clinical effect of abdominal moxibustion at the Zhongji (CV3) combined with Yiqi Tonglin Yangyin dec… | Journal of traditional Chinese medicine = Chung i tsa… 2026-09-20 04:37:03 | Source |
| Yiqi Huoxue Yangyin Decoction Ameliorates Diabetic Nephropathy by Tar… Yangyin Roujin Decoction · PMID 42713045 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source This study aimed to investigate the protective effects and underlying mechanisms of Yiqi Huoxue Yangyin Decoction (YHY)… | Diabetes, metabolic syndrome and obesity : targets and… 2026-09-20 04:37:03 | Source |
| Yiqi Huoxue Yangyin Decoction attenuates diabetic nephropathy in mice… Yangyin Roujin Decoction · PMID 42016924 | Myopathies | Thérapie génique | Publication | PubMed | Voir la publication source Diabetic nephropathy (DN) is a major complication of diabetes with limited therapeutic options. Yiqi Huoxue Yangyin Dec… | Frontiers in pharmacology 2026-09-20 04:37:03 | Source |
| Barcoded oligonucleotide system (BOLT) for targeted organ delivery. Immunotherapy · PMID 42733790 | Cancer | À vérifier | Publication | PubMed | Voir la publication source The therapeutic potential of oligonucleotides (oligos) is limited by insufficient delivery to extrahepatic tissues. In… | Bioactive materials 2026-09-20 04:36:56 | Source |
| Dual metabolic checkpoint blockade a 3D-Printed metalloplatform remod… Immunotherapy · PMID 42724565 | Cancer | Immunomodulation | Publication | PubMed | Voir la publication source The immunosuppressive tumor microenvironment limits the efficacy of therapies that target metabolism. Here we show a st… | Bioactive materials 2026-09-20 04:36:56 | Source |
| Oligosaccharide adjuvant-deferred antigen endocytosis promotes cross-… Immunotherapy · PMID 42751513 | Cancer | Immunomodulation · Thérapie génique | Publication | PubMed | Voir la publication source Antigen cross-presentation by dendritic cells (DCs) is essential for inducing cytotoxic immune responses, which are cru… | Bioactive materials 2026-09-20 04:36:56 | Source |
| Feasibility and safety of early discharge after robot-assisted uro-on… Digital care pathway for hypertension · PMID 42671715 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source Early discharge after robot-assisted uro-oncologic surgery remains limited by concerns regarding patient safety and the… | Journal of robotic surgery 2026-09-20 04:36:49 | Source |
| HomeSafe: Postpartum Hypertensive Care Enabled by Electronic Health R… Digital care pathway for hypertension · PMID 41707683 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source The objective is to present stepwise refinements to , an Epic-tethered, population-health-coordinated postpartum pathwa… | American journal of perinatology 2026-09-20 04:36:49 | Source |
| Nutraceutical and functional food: efficacy against metabolic disorde… Digital care pathway for hypertension · PMID 42603698 | Hypertension artérielle | Neuroprotection · Immunomodulation | Publication | PubMed | Voir la publication source The growing global emphasis on health consciousness has significantly increased demand for traditional and complementar… | Journal of advanced research 2026-09-20 04:36:49 | Source |
| Community-engaged design of a virtual diabetes prevention program int… Asynchronous communication with nurse · PMID 42288862 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source The Diabetes Prevention Program (DPP) is an evidence-based approach to prevent Type 2 Diabetes (T2D), the leading cause… | BMC health services research 2026-09-20 04:36:48 | Source |
| Evolving Lung Cancer Navigator Practice Through Targeted Professional… Asynchronous communication with nurse · PMID 42463006 | Cancer | À vérifier | Publication | PubMed | Voir la publication source Lung cancer remains the leading cause of cancer deaths worldwide, and it has persistent disparities in detection, treat… | Chest 2026-09-20 04:36:48 | Source |
| Mass casualty training for prehospital and emergency providers in Kig… Asynchronous communication with nurse · PMID 42751142 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source A mass casualty incident (MCI) occurs when the number of patients exceeds available healthcare resources, placing signi… | African journal of emergency medicine : Revue africain… 2026-09-20 04:36:48 | Source |
| Innovating a Teach-Back Model for Community Health Workers Led Health… Health Literacy Project · PMID 40194526 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source From 2021 to 2023, the City of Albuquerque, the University of New Mexico (UNM) Office for Community Health, the UNM Hos… | Health literacy research and practice 2026-09-20 04:36:34 | Source |
| Carotid intima-media thickness may be an early biomarker for cardiova… Impact of Ketogenic Diets on Cardiovascular Health in Adults With Epilepsy · PMID 41026111 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source To assess early signs of atherosclerosis following long-term treatment with the ketogenic diet therapy due to concerns… | Epilepsia open 2026-09-20 04:36:33 | Source |
| Impact of low-carbohydrate diet on health status: an umbrella review. Impact of Ketogenic Diets on Cardiovascular Health in Adults With Epilepsy · PMID 39385794 | Cancer | À vérifier | Publication | PubMed | Voir la publication source The prevalence of diet-related non-communicable diseases has increased. A low-carbohydrate diet (LCDs) is one of the mo… | Frontiers in nutrition 2026-09-20 04:36:33 | Source |
| The effect of anti-seizure medications on lipid values in adults with… Impact of Ketogenic Diets on Cardiovascular Health in Adults With Epilepsy · PMID 37244221 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source Certain anti-seizure medications (ASMs) adversely impact lipid values. Here, we explored the impact of ASMs on lipid va… | Epilepsy & behavior : E&B 2026-09-20 04:36:33 | Source |
| Possible role of locus coeruleus neuronal loss in age-related memory… The Role of the Locus Coeruleus in Age-related Distractibility · PMID 37694113 | Maladie d’Alzheimer | Immunomodulation | Publication | PubMed | Voir la publication source Aging is associated with a decline in cognitive abilities, including memory and attention. It is generally accepted tha… | Frontiers in neuroscience 2026-09-20 04:36:30 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||