Vue transversale de la maladie
Myopathies
Un même point d’entrée pour les études cliniques, les découvertes scientifiques, les publications et les pistes exploratoires présentes dans Biomedical Watch.
Périmètre
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1028 résultats correspondants
· 46 visibles sur cette page
dans le périmètre Myopathies
Niveau clinique
Études et traitements 434
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Efficacy Of Platelet Rich Plasma In The Treatment Of Hemiplegıc Shoul… NCT03931824 · NCT03931824 | Myopathies | Traitement symptomatique | NA | COMPLETED | In this study assessing whether platelet rich plasma injections(PRP) are e… À vérifier | ClinicalTrials.gov 2026-07-14 16:01:05 | Détail |
| GSK1278863 NCT02231190 · GSK1278863 Effects on Eccentric Exercise-Induced Muscle Damage | Myopathies | Traitement symptomatique | Phase 1 | COMPLETED | As per non-clinical studies, prolyl hydroxylase inhibitor GSK1278863 can p… À vérifier | ClinicalTrials.gov 2026-07-14 16:01:05 | Détail |
| Magnetic Resonance Imaging and Ultrasound Comparison With Load Evalua… NCT06227182 · NCT06227182 | Myopathies | Ralentissement de la progression | À vérifier | RECRUITING | Facioscapulohumeral dystrophy (FSHD) is one of the most common hereditary… À vérifier | ClinicalTrials.gov 2026-07-14 16:01:05 | Détail |
| Measurement of compartment compressibility using the CPMX1 device NCT06030635 · ACS Monitoring Charité Berlin | Myopathies | Traitement symptomatique · Thérapie génique | NA | COMPLETED | Compartment syndrome is a very serious musculoskeletal disorder, which can… À vérifier | ClinicalTrials.gov 2026-07-14 16:01:05 | Détail |
| Pain Science Education NCT07280273 · Effectiveness of Pain Science Education in Patients With Fibromyalgia Syndrome L… | Myopathies | Traitement symptomatique | NA | ACTIVE_NOT_RECRUITING | Fibromyalgia Syndrome (FMS) is a complex chronic pain disorder characteriz… À vérifier | ClinicalTrials.gov 2026-07-14 16:01:05 | Détail |
| CORRECT: COmmunity RegistRy Study Evaluating Dupuytren's Contracture… NCT01715467 · NCT01715467 | Myopathies | À vérifier | À vérifier | COMPLETED | This observational study will prospectively collect data on treatment opti… À vérifier | ClinicalTrials.gov 2026-07-12 19:40:03 | Détail |
| Creatine Monohydrate NCT00016653 · Creatine and Glutamine in Steroid-Naive Duchenne Muscular Dystrophy | Myopathies | À vérifier | Phase 2 | COMPLETED | This study will help to determine the effectiveness of glutamine and creat… À vérifier | ClinicalTrials.gov 2026-07-12 19:40:03 | Détail |
| GenPHSat injection (Safety) NCT05588401 · Evaluating Safety and Efficacy of Autologous Gene-edited Muscle Stem Cells (GenP… | Myopathies | Thérapie cellulaire | Phase 1 | UNKNOWN | This study is an investigator initiated first-in-human interventional open… À vérifier | ClinicalTrials.gov 2026-07-12 19:40:03 | Détail |
| HB-adMSCs NCT05154851 · HBCMD01- Expanded Access for the Treatment of Congenital Muscular Dystrophy. | Myopathies | À vérifier | À vérifier | NO_LONGER_AVAILABLE | This individual patient expanded access IND is requested for a patient dia… À vérifier | ClinicalTrials.gov 2026-07-12 19:40:03 | Détail |
| M5049 dose NCT05650567 · Study of M5049 in DM and PM Participants (NEPTUNIA) | Myopathies | Immunomodulation | Phase 2 | TERMINATED | The purpose of this study is to evaluate the efficacy and safety of orally… À vérifier | ClinicalTrials.gov 2026-07-12 19:40:03 | Détail |
| Muscular electrostimulation and percutaneus muscular biopsy. NCT02033057 · Muscular Electrostimulation of the Sedated and Mechanically Ventilated Criticall… | Myopathies | Ralentissement de la progression | Phase 4 | UNKNOWN | Even 20-50% of patients under sedation and mechanical ventilation develops… À vérifier | ClinicalTrials.gov 2026-07-12 19:40:03 | Détail |
| Observational Study on Cardiac Biomarkers Testing in Patients with Mu… NCT05779202 · NCT05779202 | Myopathies | À vérifier | À vérifier | COMPLETED | The objective of this study is to evaluate acute changes of cardiac tropon… À vérifier | ClinicalTrials.gov 2026-07-12 19:40:03 | Détail |
| Organ Dysfunction Associated With Intra Abdominal Pressures in Liver… NCT04463745 · NCT04463745 | Myopathies | À vérifier | À vérifier | UNKNOWN | Patients with end stage liver disease have varying degrees of intra-abdomi… À vérifier | ClinicalTrials.gov 2026-07-12 19:40:03 | Détail |
| Tadalafil NCT05195775 · Tadalafil as Adjuvant Therapy for DMD | Myopathies | À vérifier | Phase 2 | ACTIVE_NOT_RECRUITING | Examining two strategies as potential adjuvant therapies for Duchenne musc… À vérifier | ClinicalTrials.gov 2026-07-12 19:40:03 | Détail |
| trigger point injection NCT02293083 · Hyaluronidase for Trigger Point Injection in Myofascial Pain Syndrome | Myopathies | Traitement symptomatique | NA | COMPLETED | Myofascial pain syndrome (MPS) is the most common cause of persistent regi… À vérifier | ClinicalTrials.gov 2026-07-12 19:40:03 | Détail |
| Behavioral Interventions for Controlling Oral Behaviors NCT07022795 · NCT07022795 | Myopathies | Traitement symptomatique | NA | RECRUITING | Ecological momentary assessment (EMA) interventions via mobile devices can… À vérifier | ClinicalTrials.gov 2026-07-10 00:13:40 | Détail |
| Botulinum Toxin Type A for Injection NCT02280083 · A Study to Evaluate the Botulinum Toxin Type A for Injection(HengLi®) in Subject… | Myopathies | Ralentissement de la progression · Traitement symptomatique | Phase 3 | COMPLETED | This is a multicenter, double-blind, randomized, placebo-controlled study… À vérifier | ClinicalTrials.gov 2026-07-10 00:13:40 | Détail |
| Capsaicin Topical Cream NCT07598994 · Topical Capsaicin Versus Diclofenac for Chronic Temporomandibular Joint-Related… | Myopathies | Traitement symptomatique | NA | COMPLETED | The goal of this clinical trial is to compare the effectiveness and safety… À vérifier | ClinicalTrials.gov 2026-07-10 00:13:40 | Détail |
| Casimersen NCT03532542 · An Extension Study to Evaluate Casimersen or Golodirsen in Patients With Duchenn… | Myopathies | À vérifier | Phase 3 | TERMINATED | The main objective of this study is to evaluate the safety and tolerabilit… À vérifier | ClinicalTrials.gov 2026-07-10 00:13:40 | Détail |
| Desipramine NCT03726996 · Desipramine in Infantile Neuroaxonal Dystrophy (INAD). | Myopathies | Neuroprotection · Ralentissement de la progression · Traitement symptomatique | Phase 4 | TERMINATED | This is a research study to find out if clinically prescribed desipramine… À vérifier | ClinicalTrials.gov 2026-07-10 00:13:40 | Détail |
Découverte scientifique
Recherches et trouvailles 0
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune trouvaille ne correspond aux filtres. | |||||||
Bibliographie
Publications 588
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Optimizing muscle inset in free functional muscle transfer for facial… Functional muscle transfer · PMID 42585788 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Free functional muscle transfer is a well-established technique for dynamic facial reanimation; however, the inset phas… | Journal of plastic, reconstructive & aesthetic surgery… 2026-08-13 15:01:43 | Source |
| Toward an Integrated Strategy for Volumetric Muscle Loss Regeneration. Functional muscle transfer · PMID 42590005 | Myopathies | Remyélinisation indirecte / réparation · Immunomodulation · Traitement symptoma… | Publication | PubMed | Voir la publication source Volumetric muscle loss (VML) constitutes a significant clinical challenge, defined by the irreversible loss of skeletal… | Journal of clinical medicine 2026-08-13 15:01:43 | Source |
| Capsaicin and diclofenac coloaded nanoemulsion gel optimized by quali… Diclofenac 1% Topical · PMID 42578576 | Myopathies | Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source Rheumatoid arthritis (RA) is a chronic inflammatory disorder associated with progressive joint damage and pain. The pre… | Therapeutic delivery 2026-08-13 15:01:42 | Source |
| Hyaluronic acid nanoparticle as drug delivery carrier for the treatme… Diclofenac 1% Topical · PMID 42578876 | Myopathies | Immunomodulation | Publication | PubMed | Voir la publication source BackgroundAllergic conjunctivitis is an inflammatory disorder of the conjunctiva triggered by allergens. Although topic… | Bio-medical materials and engineering 2026-08-13 15:01:42 | Source |
| Successful Management of Refractory Cannabinoid Hyperemesis Syndrome… Capsaicin Topical Cream · PMID 42491286 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source Cannabinoid hyperemesis syndrome (CHS) is a debilitating disorder of chronic, heavy cannabis users characterized by cyc… | Clinical medicine insights. Case reports 2026-08-13 15:01:41 | Source |
| Fat Embolism Syndrome Following Elective Orthopedic Surgery in a Pati… Chronic Corticosteroid Therapy · PMID 42572732 | Myopathies | Immunomodulation | Publication | PubMed | Voir la publication source Duchenne muscular dystrophy (DMD) is associated with substantial perioperative morbidity due to progressive cardiopulmo… | Cureus 2026-08-13 15:01:38 | Source |
| Recalibrating Therapeutic Priorities for Duchenne Muscular Dystrophy:… Ataluren · PMID 42510866 | Myopathies | Thérapie génique | Publication | PubMed | Voir la publication source Duchenne muscular dystrophy (DMD) has, for the first time, several mutation-specific drugs in clinical use. Four exon-s… | Genes 2026-08-13 15:01:37 | Source |
| Modular intramedullary knee arthrodesis for chronic periprosthetic jo… Limb salvage · PMID 42585983 | Myopathies | Thérapie génique | Publication | PubMed | Voir la publication source Chronic periprosthetic joint infection (PJI) after total knee arthroplasty (TKA) is a severe complication causing repea… | The Knee 2026-08-13 15:01:34 | Source |
| Primary Soft Tissue Sarcomas of the Extremities: A Nationwide Retrosp… Limb salvage · PMID 42588730 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source : The aim of this study was to determine the oncologic outcomes for adult patients with primary extremity soft tissue s… | Cancers 2026-08-13 15:01:34 | Source |
| Risk of glaucoma among patients using tadalafil for lower urinary tra… Tadalafil · PMID 42552102 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source To evaluate the association between tadalafil use for lower urinary tract symptoms (LUTS) and the risk of developing gl… | The British journal of ophthalmology 2026-08-13 15:01:34 | Source |
| Multidimensional Factors Influencing the Implementation of Early Mobi… The Impact of Early Mobilization Protocol in Patients in the ICU · PMID 42504084 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source This meta-synthesis of qualitative studies aimed to explore the experiences and perspectives of healthcare providers in… | Journal of advanced nursing 2026-08-13 15:01:28 | Source |
| Stepping it Up on Temporary Mechanical Circulatory Support - Mobiliza… The Impact of Early Mobilization Protocol in Patients in the ICU · PMID 42521141 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Early mobilization and prehabilitation in patients supported with temporary mechanical circulatory support (tMCS) have… | Journal of cardiac failure 2026-08-13 15:01:28 | Source |
| Clinical Impact of Complete Revascularization Before Left Ventricular… Revascularization · PMID 42590810 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Limited information exists regarding whether coronary revascularization by percutaneous coronary intervention (PCI) pri… | Artificial organs 2026-08-13 15:01:25 | Source |
| Postoperative perfusion volume on territorial arterial spin labeling… Revascularization · PMID 42591086 | Myopathies | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Cerebral hyperperfusion syndrome (CHS) after revascularization for moyamoya disease (MMD) represents a failure of cereb… | Frontiers in physiology 2026-08-13 15:01:25 | Source |
| Cohort, gender and spatial patterns of delayed school enrolment in th… COVID-19 Pandemic and Parents of Disabled Children · PMID 42527426 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Delayed school enrolment can be an important marker for developmental delays and be associated with adverse health even… | Scientific reports 2026-08-13 15:01:22 | Source |
| School Readiness, Learning Challenges, and Lifestyle Changes Among Ch… COVID-19 Pandemic and Parents of Disabled Children · PMID 42532839 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source The COVID-19 pandemic disrupted schooling worldwide. While there is evidence of declines in academic performance, the l… | The Journal of school health 2026-08-13 15:01:22 | Source |
| From trunk and hip muscle function to class allocation: understanding… Manual muscular test · PMID 42539762 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Functional assessment in wheelchair basketball (WB) has three evaluation stages: analysis of isolated functions, combin… | Frontiers in sports and active living 2026-08-13 15:01:21 | Source |
| Precision and Error Propagation in Static MEMS-IMU Inertial Navigatio… test of walk · PMID 42590462 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source This paper investigates the precision and stochastic error propagation of navigation solutions obtained from a low-cost… | Sensors (Basel, Switzerland) 2026-08-13 15:01:20 | Source |
| The Effect of Whole-Body Cryotherapy on Exercise Capacity of Healthy… test of walk · PMID 42590172 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source : To analyze the effect of whole-body cryotherapy on exercise tolerance in healthy, training men related to their profe… | Journal of clinical medicine 2026-08-13 15:01:20 | Source |
| A qualitative study on the vulnerability factors of unintentional inj… Awareness Levels of Caregivers of Disabled Children · PMID 42577259 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Unintentional injuries represent a primary cause of child mortality worldwide. However, child injury research in China… | Frontiers in public health 2026-08-13 15:01:19 | Source |
Exploration — prudence
Pistes exploratoires 6
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| N-PPG N-PPG — modulation métabolique cérébrale | Myopathies | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation métabolique et mitohormèse N-PPG est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être pertinents pour Myopat… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |
| Vecteur Ple389 (ADORA2A) MiniPromoter Ple389 — ciblage striatal | Myopathies | Thérapie génique | Hypothèse exploratoire | Rapprochement automatique non validé | Expression génique ciblée dans les neurones striataux Vecteur Ple389 (ADORA2A) est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être per… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |
| α-Amyrin α-Amyrin — protection mitochondriale | Myopathies | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Protection mitochondriale et modulation de la pathologie Tau α-Amyrin est étudié dans Maladie d’Alzheimer et documente plusieurs axes biologiques pouvant être pertinents pour Myopa… | Rapprochement Biomedical Watch · Maladie d’Alzheimer | Détail |
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Myopathies | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation immunométabolique de la microglie 4-octyl itaconate et dérivés est étudié dans Sclérose latérale amyotrophique et documente plusieurs axes biologiques po… | Rapprochement Biomedical Watch · Sclérose latérale amy… | Détail |
| Thonningianin A Thonningianin A — neuroprotection anti-amyloïde | Myopathies | Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation du stress oxydatif et des protéines associées à Alzheimer Thonningianin A est étudié dans Maladie d’Alzheimer et documente plusieurs axes biologiques pouvant être pertinents pou… | Rapprochement Biomedical Watch · Maladie d’Alzheimer | Détail |
| Vutiglabridin Vutiglabridin — autophagie et PON2 | Myopathies | Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Activation de PON2 et stimulation de l’autophagie Vutiglabridin est étudié dans Maladie d’Alzheimer et documente plusieurs axes biologiques pouvant être pertinents pour… | Rapprochement Biomedical Watch · Maladie d’Alzheimer | Détail |