Vue transversale de la maladie
Myopathies
Un même point d’entrée pour les études cliniques, les découvertes scientifiques, les publications et les pistes exploratoires présentes dans Biomedical Watch.
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1028 résultats correspondants
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dans le périmètre Myopathies
Niveau clinique
Études et traitements 434
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Efficacy Of Platelet Rich Plasma In The Treatment Of Hemiplegıc Shoul… NCT03931824 · NCT03931824 | Myopathies | Traitement symptomatique | NA | COMPLETED | In this study assessing whether platelet rich plasma injections(PRP) are e… À vérifier | ClinicalTrials.gov 2026-07-14 16:01:05 | Détail |
| GSK1278863 NCT02231190 · GSK1278863 Effects on Eccentric Exercise-Induced Muscle Damage | Myopathies | Traitement symptomatique | Phase 1 | COMPLETED | As per non-clinical studies, prolyl hydroxylase inhibitor GSK1278863 can p… À vérifier | ClinicalTrials.gov 2026-07-14 16:01:05 | Détail |
| Magnetic Resonance Imaging and Ultrasound Comparison With Load Evalua… NCT06227182 · NCT06227182 | Myopathies | Ralentissement de la progression | À vérifier | RECRUITING | Facioscapulohumeral dystrophy (FSHD) is one of the most common hereditary… À vérifier | ClinicalTrials.gov 2026-07-14 16:01:05 | Détail |
| Measurement of compartment compressibility using the CPMX1 device NCT06030635 · ACS Monitoring Charité Berlin | Myopathies | Traitement symptomatique · Thérapie génique | NA | COMPLETED | Compartment syndrome is a very serious musculoskeletal disorder, which can… À vérifier | ClinicalTrials.gov 2026-07-14 16:01:05 | Détail |
| Pain Science Education NCT07280273 · Effectiveness of Pain Science Education in Patients With Fibromyalgia Syndrome L… | Myopathies | Traitement symptomatique | NA | ACTIVE_NOT_RECRUITING | Fibromyalgia Syndrome (FMS) is a complex chronic pain disorder characteriz… À vérifier | ClinicalTrials.gov 2026-07-14 16:01:05 | Détail |
| CORRECT: COmmunity RegistRy Study Evaluating Dupuytren's Contracture… NCT01715467 · NCT01715467 | Myopathies | À vérifier | À vérifier | COMPLETED | This observational study will prospectively collect data on treatment opti… À vérifier | ClinicalTrials.gov 2026-07-12 19:40:03 | Détail |
| Creatine Monohydrate NCT00016653 · Creatine and Glutamine in Steroid-Naive Duchenne Muscular Dystrophy | Myopathies | À vérifier | Phase 2 | COMPLETED | This study will help to determine the effectiveness of glutamine and creat… À vérifier | ClinicalTrials.gov 2026-07-12 19:40:03 | Détail |
| GenPHSat injection (Safety) NCT05588401 · Evaluating Safety and Efficacy of Autologous Gene-edited Muscle Stem Cells (GenP… | Myopathies | Thérapie cellulaire | Phase 1 | UNKNOWN | This study is an investigator initiated first-in-human interventional open… À vérifier | ClinicalTrials.gov 2026-07-12 19:40:03 | Détail |
| HB-adMSCs NCT05154851 · HBCMD01- Expanded Access for the Treatment of Congenital Muscular Dystrophy. | Myopathies | À vérifier | À vérifier | NO_LONGER_AVAILABLE | This individual patient expanded access IND is requested for a patient dia… À vérifier | ClinicalTrials.gov 2026-07-12 19:40:03 | Détail |
| M5049 dose NCT05650567 · Study of M5049 in DM and PM Participants (NEPTUNIA) | Myopathies | Immunomodulation | Phase 2 | TERMINATED | The purpose of this study is to evaluate the efficacy and safety of orally… À vérifier | ClinicalTrials.gov 2026-07-12 19:40:03 | Détail |
| Muscular electrostimulation and percutaneus muscular biopsy. NCT02033057 · Muscular Electrostimulation of the Sedated and Mechanically Ventilated Criticall… | Myopathies | Ralentissement de la progression | Phase 4 | UNKNOWN | Even 20-50% of patients under sedation and mechanical ventilation develops… À vérifier | ClinicalTrials.gov 2026-07-12 19:40:03 | Détail |
| Observational Study on Cardiac Biomarkers Testing in Patients with Mu… NCT05779202 · NCT05779202 | Myopathies | À vérifier | À vérifier | COMPLETED | The objective of this study is to evaluate acute changes of cardiac tropon… À vérifier | ClinicalTrials.gov 2026-07-12 19:40:03 | Détail |
| Organ Dysfunction Associated With Intra Abdominal Pressures in Liver… NCT04463745 · NCT04463745 | Myopathies | À vérifier | À vérifier | UNKNOWN | Patients with end stage liver disease have varying degrees of intra-abdomi… À vérifier | ClinicalTrials.gov 2026-07-12 19:40:03 | Détail |
| Tadalafil NCT05195775 · Tadalafil as Adjuvant Therapy for DMD | Myopathies | À vérifier | Phase 2 | ACTIVE_NOT_RECRUITING | Examining two strategies as potential adjuvant therapies for Duchenne musc… À vérifier | ClinicalTrials.gov 2026-07-12 19:40:03 | Détail |
| trigger point injection NCT02293083 · Hyaluronidase for Trigger Point Injection in Myofascial Pain Syndrome | Myopathies | Traitement symptomatique | NA | COMPLETED | Myofascial pain syndrome (MPS) is the most common cause of persistent regi… À vérifier | ClinicalTrials.gov 2026-07-12 19:40:03 | Détail |
| Behavioral Interventions for Controlling Oral Behaviors NCT07022795 · NCT07022795 | Myopathies | Traitement symptomatique | NA | RECRUITING | Ecological momentary assessment (EMA) interventions via mobile devices can… À vérifier | ClinicalTrials.gov 2026-07-10 00:13:40 | Détail |
| Botulinum Toxin Type A for Injection NCT02280083 · A Study to Evaluate the Botulinum Toxin Type A for Injection(HengLi®) in Subject… | Myopathies | Ralentissement de la progression · Traitement symptomatique | Phase 3 | COMPLETED | This is a multicenter, double-blind, randomized, placebo-controlled study… À vérifier | ClinicalTrials.gov 2026-07-10 00:13:40 | Détail |
| Capsaicin Topical Cream NCT07598994 · Topical Capsaicin Versus Diclofenac for Chronic Temporomandibular Joint-Related… | Myopathies | Traitement symptomatique | NA | COMPLETED | The goal of this clinical trial is to compare the effectiveness and safety… À vérifier | ClinicalTrials.gov 2026-07-10 00:13:40 | Détail |
| Casimersen NCT03532542 · An Extension Study to Evaluate Casimersen or Golodirsen in Patients With Duchenn… | Myopathies | À vérifier | Phase 3 | TERMINATED | The main objective of this study is to evaluate the safety and tolerabilit… À vérifier | ClinicalTrials.gov 2026-07-10 00:13:40 | Détail |
| Desipramine NCT03726996 · Desipramine in Infantile Neuroaxonal Dystrophy (INAD). | Myopathies | Neuroprotection · Ralentissement de la progression · Traitement symptomatique | Phase 4 | TERMINATED | This is a research study to find out if clinically prescribed desipramine… À vérifier | ClinicalTrials.gov 2026-07-10 00:13:40 | Détail |
Découverte scientifique
Recherches et trouvailles 0
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune trouvaille ne correspond aux filtres. | |||||||
Bibliographie
Publications 588
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| A Randomized Controlled Trial of Dual Upper-Extremity Training [DUET]… HD-tDCS treatments · PMID 42438177 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source Corticobasal syndrome (CBS) is a progressive neurodegenerative condition characterized by asymmetric limb rigidity, apr… | Movement disorders clinical practice 2026-08-13 15:03:23 | Source |
| Estimating the Minimal Detectable Change (MDC) of the Disability of t… Focal Extracorporeal Shock Wave Therapy (ESWT) · PMID 42526637 | Myopathies | Ralentissement de la progression · Traitement symptomatique | Publication | PubMed | Voir la publication source Idiopathic frozen shoulder is a disabling condition characterized by pain and restricted range of motion, often evaluat… | Orthopaedics & traumatology, surgery & research : OTSR 2026-08-13 15:03:22 | Source |
| Extracorporeal shockwave therapy in tissue repair and regeneration. Focal Extracorporeal Shock Wave Therapy (ESWT) · PMID 42525197 | Myopathies | Remyélinisation indirecte / réparation · Thérapie cellulaire | Publication | PubMed | Voir la publication source In this article, we aim to provide a comprehensive overview of the development of shockwave therapy in medicine, from t… | Wiener medizinische Wochenschrift (1946) 2026-08-13 15:03:22 | Source |
| Identifying the Diagnostic Challenges and Indicators of Orthostatic T… Data Collection of Standard Care of Patients in the EMG Section · PMID 40265716 | Myopathies | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source The diagnosis of orthostatic tremor (OT) is challenging because of its non-specific symptoms and a broad range of diffe… | Movement disorders clinical practice 2026-08-13 15:03:20 | Source |
| Utilization of Preoperative Electrodiagnostic Studies for Carpal Tunn… Data Collection of Standard Care of Patients in the EMG Section · PMID 27068003 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Given the lack of a reference standard diagnostic tool for carpal tunnel syndrome (CTS), we conducted a population-leve… | The Journal of hand surgery 2026-08-13 15:03:20 | Source |
| Applicability of an Immersive Virtual Reality Exercise Training Syste… Dual-task cycling · PMID 35878115 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Virtual reality is a computer-generated simulation of a real or imaginary three-dimensional environment that has entere… | Sports (Basel, Switzerland) 2026-08-13 15:03:19 | Source |
| Event-related brain potentials reveal enhancing and compensatory mech… Dual-task cycling · PMID 37845733 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Various neurocognitive tests have shown that cycling enhances cognitive performance compared to resting. Event-related… | BMC sports science, medicine & rehabilitation 2026-08-13 15:03:19 | Source |
| Advancing treatment of spinal muscular atrophy through inhibition of… Apitegromab · PMID 41566720 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source In spinal muscular atrophy (SMA), irreversible loss of spinal motor neurons and progressive skeletal muscle atrophy cau… | Expert review of neurotherapeutics 2026-08-13 15:03:18 | Source |
| Apitegromab for lean mass preservation during tirzepatide-induced wei… Apitegromab · PMID 42260100 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Loss of lean mass in proportion to total weight loss is observed with incretin mimetic therapies such as tirzepatide an… | Nature medicine 2026-08-13 15:03:18 | Source |
| Impact of Virtual Reality-Based Task-Oriented Training for Enhancing… Standard rehabilitation · PMID 42581516 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source BACKGROUND Stroke frequently causes persistent motor impairment and dependence in activities of daily living (ADL). Vir… | Medical science monitor : international medical journa… 2026-08-13 15:03:17 | Source |
| The Role of Radial Shockwave Therapy in Reducing Spasticity and Impro… Standard rehabilitation · PMID 42589983 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source : Spasticity resulting from a stroke usually develops within a few weeks or months of the incident and occurs in approx… | Journal of clinical medicine 2026-08-13 15:03:17 | Source |
| Exploring somatosensory temporal discrimination deficits in rheumatoi… Constant Current Stimulator · PMID 41316482 | Myopathies | Ralentissement de la progression | Publication | PubMed | Voir la publication source Objective- Somatosensory deficits in rheumatoid arthritis (RA) have not been adequately investigated, despite their pot… | Advances in rheumatology (London, England) 2026-08-13 15:03:15 | Source |
| Optimizing Movement Performance with Altered Sensation: An Examinatio… Constant Current Stimulator · PMID 37759903 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Two experiments were conducted to assess the impact of induced paresthesia on movement parameters of goal-directed aimi… | Brain sciences 2026-08-13 15:03:15 | Source |
| Degradation-Robust Hue Prior Network for Low-Light Rainy Image Restor… SRP-1003 SC Injection · PMID 42590629 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Restoring images captured in low-light rainy scenes is challenging because brightness degradation and rain corruption a… | Sensors (Basel, Switzerland) 2026-08-13 15:03:14 | Source |
| Elegans-Inspired Magnetic Polyurethane Soft Robot (MPSR) for Closed V… SRP-1003 SC Injection · PMID 42590852 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Secondary hemorrhage is inevitable during the transportation of casualties in harsh environments, and reoperative treat… | Advanced healthcare materials 2026-08-13 15:03:14 | Source |
| Remifentanil attenuates LPS-induced hepatic injury by modulating NRF2… SRP-1003 IV Infusion · PMID 42584673 | Myopathies | Neuroprotection · Immunomodulation · Thérapie génique | Publication | PubMed | Voir la publication source Lipopolysaccharide (LPS)-induced sepsis causes widespread inflammation and liver dysfunction, driven by oxidative stres… | Naunyn-Schmiedeberg's archives of pharmacology 2026-08-13 15:03:13 | Source |
| Transient Neonatal Myasthenia Gravis in a Newborn Infant Presenting t… SRP-1003 IV Infusion · PMID 42583073 | Myopathies | Thérapie génique | Publication | PubMed | Voir la publication source A four-day-old female born full term via uncomplicated vaginal delivery presented to the emergency department with poor… | Cureus 2026-08-13 15:03:13 | Source |
| AOC 1044 induces exon 44 skipping and restores dystrophin protein in… AOC 1044 · PMID 40183632 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Duchenne muscular dystrophy (DMD) is a severe disorder caused by mutations in the dystrophin gene, resulting in loss of… | Nucleic acids research 2026-08-13 15:03:12 | Source |
| Antibodies to watch in 2026. delpacibart zotadirsen · PMID 41560619 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source The Antibodies to Watch article series provides annual updates on commercial late-stage clinical development, regulator… | mAbs 2026-08-13 15:03:10 | Source |
| A hospital based epidemiological study of genetically determined musc… 3 Year Follow up on ANO5 Patients · PMID 32146000 | Myopathies | Thérapie génique | Publication | PubMed | Voir la publication source We determined the prevalence of genetically determined neuromuscular diseases in adult Norwegian patients from Hordalan… | Neuromuscular disorders : NMD 2026-08-13 15:03:09 | Source |
Exploration — prudence
Pistes exploratoires 6
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| N-PPG N-PPG — modulation métabolique cérébrale | Myopathies | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation métabolique et mitohormèse N-PPG est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être pertinents pour Myopat… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |
| Vecteur Ple389 (ADORA2A) MiniPromoter Ple389 — ciblage striatal | Myopathies | Thérapie génique | Hypothèse exploratoire | Rapprochement automatique non validé | Expression génique ciblée dans les neurones striataux Vecteur Ple389 (ADORA2A) est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être per… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |
| α-Amyrin α-Amyrin — protection mitochondriale | Myopathies | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Protection mitochondriale et modulation de la pathologie Tau α-Amyrin est étudié dans Maladie d’Alzheimer et documente plusieurs axes biologiques pouvant être pertinents pour Myopa… | Rapprochement Biomedical Watch · Maladie d’Alzheimer | Détail |
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Myopathies | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation immunométabolique de la microglie 4-octyl itaconate et dérivés est étudié dans Sclérose latérale amyotrophique et documente plusieurs axes biologiques po… | Rapprochement Biomedical Watch · Sclérose latérale amy… | Détail |
| Thonningianin A Thonningianin A — neuroprotection anti-amyloïde | Myopathies | Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation du stress oxydatif et des protéines associées à Alzheimer Thonningianin A est étudié dans Maladie d’Alzheimer et documente plusieurs axes biologiques pouvant être pertinents pou… | Rapprochement Biomedical Watch · Maladie d’Alzheimer | Détail |
| Vutiglabridin Vutiglabridin — autophagie et PON2 | Myopathies | Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Activation de PON2 et stimulation de l’autophagie Vutiglabridin est étudié dans Maladie d’Alzheimer et documente plusieurs axes biologiques pouvant être pertinents pour… | Rapprochement Biomedical Watch · Maladie d’Alzheimer | Détail |