Vue transversale de la maladie
Myopathies
Un même point d’entrée pour les études cliniques, les découvertes scientifiques, les publications et les pistes exploratoires présentes dans Biomedical Watch.
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1028 résultats correspondants
· 46 visibles sur cette page
dans le périmètre Myopathies
Niveau clinique
Études et traitements 434
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Multimodal Management of Neck and Back Pain in the Emergency Departme… NCT05221125 · NCT05221125 | Myopathies | Traitement symptomatique | Non applicable | COMPLETED | The purpose of this study is to assess the feasibility and acceptability o… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| Positional Release Technique NCT07644988 · PRT-PIR-LS — Comparing Two Muscle Relaxation Techniques for Neck Pain | Myopathies | Ralentissement de la progression · Traitement symptomatique | Non applicable | ACTIVE_NOT_RECRUITING | Levator scapulae muscle tightness is a common cause of neck pain due to po… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| Repeated Bout Effect i Neuromuscular Diseases NCT05599568 · NCT05599568 | Myopathies | À vérifier | Non applicable | COMPLETED | The repeated bout effect (RBE) refers to the adaptation whereby a single b… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| Satralizumab NCT06450639 · SHIELD DMD — A Study to Assess the Efficacy and Safety of Satralizumab in Duchen… | Myopathies | À vérifier | Phase 2 | ACTIVE_NOT_RECRUITING | The purpose of this study is to assess the efficacy, safety, pharmacokinet… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| SGT-003 NCT07160634 · A Study of SGT-003 Gene Therapy in Ambulant Males With Duchenne Muscular Dystrop… | Myopathies | Thérapie génique | Phase 3 | RECRUITING | This is a Phase 3, double-blind, placebo-controlled study with the primary… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| Simple electrolysis percutaneous NCT07695792 · Efficacy of Therapeutic Percutaneous Electrolysis Simple vs Multiple vs Laser Th… | Myopathies | Traitement symptomatique | Non applicable | COMPLETED | Supraspinatus tendinopathy is one of the main pathologies that cause funct… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| Temporomandibular Disorders With and Without Chronic Neck Pain NCT07750743 · NCT07750743 | Myopathies | Ralentissement de la progression · Traitement symptomatique | À vérifier | COMPLETED | Temporomandibular disorders (TMD) are common musculoskeletal conditions fr… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| The Effects of Tyrosol and Creatine on Exercise Performance and Cogni… NCT07756658 · NCT07756658 | Myopathies | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This study will be a randomized, double-blind, placebo-controlled trial. I… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| TREAT-EXT — Trial Readiness and Endpoint Assessment in Pediatric Myot… NCT06747884 · NCT06747884 | Myopathies | À vérifier | À vérifier | RECRUITING | This is a natural history study to improve the types of assessments and bi… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| Ublituximab NCT07103746 · SUMMIT — Ublituximab in Autoantibody Positive Immune Mediated Necrotizing Myopat… | Myopathies | Traitement symptomatique | Phase 2 | RECRUITING | The proposed study is a pilot study of ublituximab involving people with m… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| VX-670 NCT06926621 · A Study of Long-term Safety and Efficacy of VX-670 in Participants With Myotonic… | Myopathies | À vérifier | Phase 2 | ENROLLING_BY_INVITATION | The purpose of the study is to evaluate the long-term safety and tolerabil… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| Trans-auricular Vagus Nerve Stimulation: Low Intensity Étude non communiquée | Myopathies | À vérifier | Non applicable | Actif | The purpose of this study is to compare two approaches to cognitive rehabi… À vérifier | ClinicalTrials.gov 2026-08-12 | Détail |
| post isometric relaxation Étude non communiquée | Myopathies | Ralentissement de la progression · Traitement symptomatique | Non applicable | Actif | Levator scapulae muscle tightness is a common cause of neck pain due to po… À vérifier | ClinicalTrials.gov 2026-08-11 | Détail |
| Cadwell Guardian System Étude non communiquée | Myopathies | Traitement symptomatique | Non applicable | Actif | The goal of this clinical trial is to evaluate whether dorsal root electri… À vérifier | ClinicalTrials.gov 2026-08-10 | Détail |
| Standard rehabilitation Étude non communiquée | Myopathies | Traitement symptomatique | Non applicable | Actif | This study aims to evaluate the effectiveness of dry needling in patients… À vérifier | ClinicalTrials.gov 2026-08-09 | Détail |
| CMDPROS — Congenital Muscle Disease Study of Patient and Family Repor… NCT01403402 · NCT01403402 | Myopathies | Thérapie génique | À vérifier | RECRUITING | The Congenital Muscle Disease Patient and Proxy Reported Outcome Study (CM… À vérifier | ClinicalTrials.gov 2026-08-08 00:54:21 | Détail |
| Impact of Clinical Pharmacy Services on Medication Cost and Hospitali… NCT05952388 · NCT05952388 | Myopathies | À vérifier | NA | WITHDRAWN | The purpose of this study is to evaluate the effects of pharmaceutical car… À vérifier | ClinicalTrials.gov 2026-08-08 00:54:21 | Détail |
| Limb Girdle Muscular Dystrophy Type 2E Recruitment Study NCT03492346 · NCT03492346 | Myopathies | Thérapie génique | À vérifier | UNKNOWN | This study is to recruit and establish baseline measurements for potential… À vérifier | ClinicalTrials.gov 2026-08-08 00:54:21 | Détail |
| Stem Cell NCT02245711 · Cell Therapy in Limb Girdle Muscular Dystrophy | Myopathies | Thérapie cellulaire | Phase 1 | WITHDRAWN | The purpose of this study was to study the effect of stem cell therapy on… À vérifier | ClinicalTrials.gov 2026-08-08 00:54:21 | Détail |
| BFRT for Severe Lower Extremity Muscle Atrophy NCT04357184 · NCT04357184 | Myopathies | Traitement symptomatique | NA | COMPLETED | Muscle weakness or atrophy is a common condition following acute and chron… À vérifier | ClinicalTrials.gov 2026-08-08 00:54:20 | Détail |
Découverte scientifique
Recherches et trouvailles 0
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune trouvaille ne correspond aux filtres. | |||||||
Bibliographie
Publications 588
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Clinical and genetic features of anoctaminopathy in Saudi Arabia. 3 Year Follow up on ANO5 Patients · PMID 25864073 | Myopathies | Ralentissement de la progression · Traitement symptomatique | Publication | PubMed | Voir la publication source Characterization of the phenotypic, pathological, radiological, and genetic findings in 2 Saudi Arabian families with a… | Neurosciences (Riyadh, Saudi Arabia) 2026-08-13 15:03:09 | Source |
| Individualized 3D-Printed Titanium Mesh-Assisted Alveolar Reconstruct… 3d printed Stabilization splint · PMID 42551905 | Myopathies | Remyélinisation indirecte / réparation | Publication | PubMed | Voir la publication source Medication-related osteonecrosis of the jaw is a severe complication of antiresorptive therapy that often necessitates… | The Journal of oral implantology 2026-08-13 15:03:08 | Source |
| Trueness and scanning time of complete-arch intraoral scans of edentu… 3d printed Stabilization splint · PMID 42521277 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source This in vitro study evaluated the influence of the presence of saliva in varying levels on the trueness and scanning ti… | Journal of prosthodontics : official journal of the Am… 2026-08-13 15:03:08 | Source |
| Beyond the first bout: Adaptations to repeated injuries across physio… Repeated Bout Effect i Neuromuscular Diseases · PMID 42186361 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Skeletal muscle exhibits remarkable plasticity following injury, yet most research has focused on responses to a single… | Physiological reports 2026-08-13 15:03:07 | Source |
| Clear Aligners and Patient-Specific Plates in Orthognathic Surgery fo… Conventional Stabilization Splints · PMID 42535967 | Myopathies | Thérapie génique | Publication | PubMed | Voir la publication source Orthognathic surgery in patients with severe dental and periodontal compromise represents a significant clinical challe… | The Journal of craniofacial surgery 2026-08-13 15:03:07 | Source |
| Impact of Powdered Tart Cherry Supplementation on Performance Recover… Repeated Bout Effect i Neuromuscular Diseases · PMID 41683264 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Due to its high polyphenol content and purported capability to mitigate post-exercise muscle soreness and promote recov… | Nutrients 2026-08-13 15:03:07 | Source |
| Two-Stage Management of Severe Maxillary Atrophy With Maxillary Advan… Conventional Stabilization Splints · PMID 42536014 | Myopathies | Thérapie génique | Publication | PubMed | Voir la publication source Severe maxillary atrophy is a significant challenge for implant-supported rehabilitation, often requiring complex recon… | The Journal of craniofacial surgery 2026-08-13 15:03:07 | Source |
| Effects of daily multivitamin-multimineral and cocoa extract suppleme… DNA Methylation in PMR · PMID 41803341 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Large-scale randomized trials have found that multivitamin-multimineral (MVM) supplements and cocoa flavanols may benef… | Nature medicine 2026-08-13 15:03:04 | Source |
| Multi-gene DNA methylation profiles of tumor suppressor genes for pro… DNA Methylation in PMR · PMID 41634637 | Myopathies | Thérapie cellulaire | Publication | PubMed | Voir la publication source BACKGROUND: This study aimed to identify prognostic biomarkers for gastric cancer (GC) by analyzing the methylation sta… | BMC cancer 2026-08-13 15:03:04 | Source |
| The effects of reformer pilates on postural alignment, body appreciat… Effects of Pilates and Desk-Based Exercise on Office Workers · PMID 41024232 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source With the increasing prevalence of sedentary work life, misalignments in postural alignment and psychosocial health prob… | BMC sports science, medicine & rehabilitation 2026-08-13 15:03:03 | Source |
| Comprehensive review of adverse reactions and toxicology in ASO-based… ENTR-601-44 · PMID 38983605 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Duchenne Muscular Dystrophy (DMD) is a devastating X-linked genetic disorder characterized by progressive muscle degene… | Current research in toxicology 2026-08-13 15:03:02 | Source |
| Comparison of post-isometric relaxation and active static stretching… post isometric relaxation · PMID 42092043 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Hamstring tightness is a common musculoskeletal concern that can impair posture, restrict mobility, and predispose indi… | Scientific reports 2026-08-13 15:03:01 | Source |
| Effectiveness of manual therapy targeting hamstring tightness in knee… post isometric relaxation · PMID 42465096 | Myopathies | Ralentissement de la progression · Traitement symptomatique | Publication | PubMed | Voir la publication source Knee osteoarthritis (KOA) is a leading cause of pain and disability worldwide. Hamstring tightness alters biomechanics… | Frontiers in medicine 2026-08-13 15:03:01 | Source |
| Positional release technique in the management of low back pain: A sy… Positional Release Technique · PMID 40954594 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source This systematic review aimed to evaluate the effects of positional release technique (PRT) on clinically relevant outco… | Journal of bodywork and movement therapies 2026-08-13 15:03:00 | Source |
| Positional Release Technique Versus Muscle Energy Technique for Patie… Positional Release Technique · PMID 41873799 | Myopathies | Ralentissement de la progression · Traitement symptomatique | Publication | PubMed | Voir la publication source This study, being a pilot research, explored the comparative short-term results, as well as the feasibility, of using p… | Pain research & management 2026-08-13 15:03:00 | Source |
| Gene therapy in Duchenne muscular dystrophy. SGT-003 · PMID 41391912 | Myopathies | Thérapie génique | Publication | PubMed | Voir la publication source Duchenne muscular dystrophy (DMD) is a severe X-linked myopathy caused by mutations in the DMD gene, resulting in the a… | Archives de pediatrie : organe officiel de la Societe… 2026-08-13 15:02:59 | Source |
| Effects of connective tissue massage and kinesiotaping in patients wi… KinesioTape — The Effect of KT on Tissue Parameters · PMID 39593407 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source Fibromyalgia (FM) is a common soft tissue rheumatic disease. There is no established treatment plan for FM. Current tre… | Journal of bodywork and movement therapies 2026-08-13 15:02:58 | Source |
| Effects of tape and Kinesiotape on ankle range of motion, Single Leg… KinesioTape — The Effect of KT on Tissue Parameters · PMID 40258080 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source The prevention and management of injuries in runners is a key area of research in sports medicine. Fatigue during runni… | PloS one 2026-08-13 15:02:58 | Source |
| Clinical Use of Interleukin-6 Blockade in Neuroimmunological Disorder… Satralizumab · PMID 42583026 | Myopathies | Remyélinisation · Neuroprotection · Immunomodulation | Publication | PubMed | Voir la publication source Interleukin-6 (IL-6) is a multifunctional cytokine that plays a critical role in immune regulation, host defense, and t… | Noro psikiyatri arsivi 2026-08-13 15:02:57 | Source |
| Reduced drug use and hospitalization rates in patients undergoing hem… Impact of Clinical Pharmacy Services on Medication Cost and Hospitalization Rates in Hemodialy… | Myopathies | À vérifier | Publication | PubMed | Voir la publication source To investigate the impact of a pharmaceutical care program managed by clinical pharmacists on drug use, drug costs, hos… | Pharmacotherapy 2026-08-13 15:02:53 | Source |
Exploration — prudence
Pistes exploratoires 6
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| N-PPG N-PPG — modulation métabolique cérébrale | Myopathies | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation métabolique et mitohormèse N-PPG est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être pertinents pour Myopat… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |
| Vecteur Ple389 (ADORA2A) MiniPromoter Ple389 — ciblage striatal | Myopathies | Thérapie génique | Hypothèse exploratoire | Rapprochement automatique non validé | Expression génique ciblée dans les neurones striataux Vecteur Ple389 (ADORA2A) est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être per… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |
| α-Amyrin α-Amyrin — protection mitochondriale | Myopathies | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Protection mitochondriale et modulation de la pathologie Tau α-Amyrin est étudié dans Maladie d’Alzheimer et documente plusieurs axes biologiques pouvant être pertinents pour Myopa… | Rapprochement Biomedical Watch · Maladie d’Alzheimer | Détail |
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Myopathies | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation immunométabolique de la microglie 4-octyl itaconate et dérivés est étudié dans Sclérose latérale amyotrophique et documente plusieurs axes biologiques po… | Rapprochement Biomedical Watch · Sclérose latérale amy… | Détail |
| Thonningianin A Thonningianin A — neuroprotection anti-amyloïde | Myopathies | Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation du stress oxydatif et des protéines associées à Alzheimer Thonningianin A est étudié dans Maladie d’Alzheimer et documente plusieurs axes biologiques pouvant être pertinents pou… | Rapprochement Biomedical Watch · Maladie d’Alzheimer | Détail |
| Vutiglabridin Vutiglabridin — autophagie et PON2 | Myopathies | Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Activation de PON2 et stimulation de l’autophagie Vutiglabridin est étudié dans Maladie d’Alzheimer et documente plusieurs axes biologiques pouvant être pertinents pour… | Rapprochement Biomedical Watch · Maladie d’Alzheimer | Détail |