Vue transversale de la maladie
Myopathies
Un même point d’entrée pour les études cliniques, les découvertes scientifiques, les publications et les pistes exploratoires présentes dans Biomedical Watch.
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1028 résultats correspondants
· 46 visibles sur cette page
dans le périmètre Myopathies
Niveau clinique
Études et traitements 434
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Yoomi Physical Therapy Software NCT05815017 · YOOMI: Effect of Gamified Physical Therapy Exercise Software on Inpatient Mobili… | Myopathies | À vérifier | Non applicable | COMPLETED | Patients admitted to the hospital often develop functional impairments due… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:35 | Détail |
| 3 Year Follow up on ANO5 Patients NCT05206617 · NCT05206617 | Myopathies | Ralentissement de la progression | À vérifier | ACTIVE_NOT_RECRUITING | The aim of the study is to investigate progression in muscle affection in… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| ANO5 MRI — MRI-phenotyping of Patients With Pathogenic Anoctamin 5 Va… NCT05102799 · NCT05102799 | Myopathies | Thérapie génique | À vérifier | ACTIVE_NOT_RECRUITING | A large cohort of MRI scans from patients with pathogenic variants in the… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| Apitegromab NCT07435129 · Phase 2 Study Evaluating Apitegromab for the Treatment of FSHD | Myopathies | À vérifier | Phase 2 | RECRUITING | A randomized Phase 2 study to evaluate the efficacy and safety of apitegro… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| Botulinum toxin type A NCT07758322 · Efficacy of Focused Shock Wave Therapy Before and After Botulinum Toxin Injectio… | Myopathies | Traitement symptomatique | Non applicable | ACTIVE_NOT_RECRUITING | The main purpose of this study is to determine which is the best dose of a… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| Constant Current Stimulator NCT07715006 · Dorsal Root Electrical Stimulation in Children With Cerebral Palsy | Myopathies | Traitement symptomatique | Non applicable | RECRUITING | The goal of this clinical trial is to evaluate whether dorsal root electri… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| Conventional Stabilization Splints NCT07760428 · Comparison of Conventional,3D Printed and Novel Hybrid Stabilization Splints in… | Myopathies | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | Occlusal splint therapy is a well-established conservative approach for th… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| delpacibart zotadirsen NCT07250737 · Managed Access Program for Del-zota in Participants With DMD Mutations Amenable… | Myopathies | À vérifier | À vérifier | AVAILABLE | The purpose of this Managed Access Program is to allow access to delpaciba… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| DNA Methylation in PMR NCT07748195 · NCT07748195 | Myopathies | À vérifier | À vérifier | NOT_YET_RECRUITING | Polymyalgia Rheumatica (PMR) is treated with corticosteroids; however, lon… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| Dry Needling NCT07321483 · Reflex Therapy of Temporomandibular Dysfunctions | Myopathies | Traitement symptomatique | Non applicable | RECRUITING | This randomized clinical trial will aim to compare the effectiveness of dr… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| Dual-task cycling NCT07580365 · VirtualPark_Pediatric | Myopathies | À vérifier | Non applicable | RECRUITING | The goal of this clinical trial is to assess the effects of a dual-task, m… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| Effects of Curcumin-Piperine Supplementation in Fibromyalgia NCT07753018 · NCT07753018 | Myopathies | Neuroprotection · Immunomodulation · Traitement symptomatique | Phase 2 | NOT_YET_RECRUITING | The goal of this clinical trail is to evaluate the effectiveness and safet… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| Effects of Pilates and Desk-Based Exercise on Office Workers NCT07763925 · NCT07763925 | Myopathies | Traitement symptomatique | Non applicable | COMPLETED | This study evaluated whether adding Pilates exercises to a desk-based exer… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| EXCEL — A Study to Check Liver Health in Boys With XLMTM, a Serious G… NCT06581146 · NCT06581146 | Myopathies | Traitement symptomatique · Thérapie génique | À vérifier | RECRUITING | XLMTM (X-linked myotubular myopathy) is a serious genetic muscle condition… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| Fibromyalgia Syndrome on Anthropometric and Ultrasonographic Measurem… NCT06536894 · NCT06536894 | Myopathies | À vérifier | À vérifier | COMPLETED | Obstructive type sleep apnea syndrome is a clinical condition characterize… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| GRT6019 NCT07347548 · A Trial to Investigate the Safety and Pharmacokinetics of GRT6019 in Healthy Mal… | Myopathies | À vérifier | Phase 1 | COMPLETED | The purpose of this trial is to assess the safety, tolerability, and PK of… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| HD-tDCS treatments NCT04606095 · Explosive Synchronization of Brain Network Activity in Chronic Pain | Myopathies | Traitement symptomatique | Non applicable | ACTIVE_NOT_RECRUITING | This project is being conducted to evaluate the impact of explosive synchr… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| INFLAME-BANK — Inflammatory Disease Biobank for Immunophenotyping and… NCT07737470 · NCT07737470 | Myopathies | Immunomodulation · Thérapie génique | À vérifier | NOT_YET_RECRUITING | INFLAME-BANK is a French multicenter prospective observational ancillary s… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| KER-065 NCT07704099 · Safety and Efficacy of KER-065 in Participants With Duchenne Muscular Dystrophy | Myopathies | À vérifier | Phase 2 | NOT_YET_RECRUITING | The purpose of this study is to evaluate the safety, tolerability, pharmac… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| KinesioTape — The Effect of KT on Tissue Parameters NCT06012305 · NCT06012305 | Myopathies | Traitement symptomatique | Non applicable | COMPLETED | Myofascial pain is a concept that refers to pain from trigger points. The… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
Découverte scientifique
Recherches et trouvailles 0
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune trouvaille ne correspond aux filtres. | |||||||
Bibliographie
Publications 588
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| New Cortisol Thresholds for the Diagnosis of Adrenal Insufficiency Us… Chronic Corticosteroid Therapy · PMID 41975776 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source The low-dose Synacthen stimulation test (LD-SST) is the reference dynamic test for diagnosing glucocorticoid-induced ad… | Diagnostics (Basel, Switzerland) 2026-07-08 20:15:00 | Source |
| Very late stent thrombosis associated with stent malapposition and un… Chronic Corticosteroid Therapy · PMID 41972237 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Kounis syndrome (KS) is an acute coronary syndrome triggered by allergic or hypersensitivity reactions and is classifie… | European heart journal. Case reports 2026-07-08 20:15:00 | Source |
| Investigation of the relationship between dual-task performance and f… Fear of Falling in Muscular Dystrophy · PMID 40107171 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source The aim of this study is to investigate the variations in dual-task performance between children with Duchenne Muscular… | Research in developmental disabilities 2026-07-08 20:14:58 | Source |
| Tests of dynamic balance, motor function and fear of falling as indic… Fear of Falling in Muscular Dystrophy · PMID 40645042 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source This study aims to examine dynamic balance, motor function, and fear of falling (FOF) as indicators of fall risk in chi… | European journal of paediatric neurology : EJPN : offi… 2026-07-08 20:14:58 | Source |
| New insights into an old vaccine: potency and breadth of neutralizing… Yellow Fever vaccine (17D) · PMID 40766119 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source The yellow fever vaccine 17D has controlled yellow fever for almost 90 years and is considered highly successful. Howev… | medRxiv : the preprint server for health sciences 2026-07-08 20:14:57 | Source |
| New insights into an old vaccine: potency and breadth of neutralizing… Yellow Fever vaccine (17D) · PMID 41670061 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source The yellow fever vaccine 17D has controlled yellow fever for almost 90 years and is considered highly successful. Howev… | The Journal of infectious diseases 2026-07-08 20:14:57 | Source |
| Early mobilization in the neurotrauma intensive care unit: a service… The Impact of Early Mobilization Protocol in Patients in the ICU · PMID 42388707 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Early mobilization (EM) refers to active exercise commenced while patients are on the intensive care unit (ICU). Althou… | Frontiers in neurology 2026-07-08 20:14:56 | Source |
| Nursing-led stepwise pain-management protocol improves postoperative… The Impact of Early Mobilization Protocol in Patients in the ICU · PMID 42007103 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source To assess the impact of a stepwise pain-management protocol on postoperative recovery, pain control, complication rate,… | American journal of translational research 2026-07-08 20:14:56 | Source |
| Experiences of women with disabilities accessing maternal and newborn… Awareness Levels of Caregivers of Disabled Children · PMID 42192434 | Myopathies | Ralentissement de la progression · Thérapie génique | Publication | PubMed | Voir la publication source Despite global commitments to inclusive and equitable maternal and newborn health (MNH) care, women with disabilities i… | Reproductive health 2026-07-08 20:14:50 | Source |
| The effect of a mindfulness-based stress reduction program on stress… Awareness Levels of Caregivers of Disabled Children · PMID 42297152 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Mothers of children with physical disabilities often experience caregiving-related stress that may negatively affect th… | Journal of affective disorders 2026-07-08 20:14:50 | Source |
| One-day rejuvenation: a preliminary case series of a multimodal proto… Botulinum toxin type A · PMID 42418230 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Same-day multimodal aesthetic treatments may optimize patient convenience, but concerns remain regarding possible therm… | Journal of cosmetic and laser therapy : official publi… 2026-07-08 20:14:49 | Source |
| Activation of GABAR alleviates colitis by reprogramming macrophage po… baclofen · PMID 42413737 | Myopathies | Immunomodulation | Publication | PubMed | Voir la publication source Although the metabotropic GABA type B receptor (GABAR) has emerged as an immune modulator, its specific role in regulat… | Biochemical pharmacology 2026-07-08 20:14:47 | Source |
| Long-Term Effects of Early Postnatal Administration of R-Baclofen on… baclofen · PMID 42411441 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source Contactin-associated protein-like 2 () is a highly expressed gene during development, coding for the cell adhesion mole… | Journal of integrative neuroscience 2026-07-08 20:14:47 | Source |
| Intermittent Theta-Burst Stimulation and Depressive Symptoms in Major… Intermittent theta burst stimulation · PMID 42418203 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source Intermittent theta-burst stimulation (iTBS) is an established treatment for major depressive disorder (MDD), but sham-c… | JAMA network open 2026-07-08 20:14:19 | Source |
| Intermittent Theta-Burst Stimulation for Depression-Delineating Speci… Intermittent theta burst stimulation · PMID 42418204 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Résumé non disponible dans la base locale. | JAMA network open 2026-07-08 20:14:19 | Source |
| Feasibility and behavioral impact of a wearable-supported digital hea… test of walk · PMID 42416388 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source This proof-of-concept study examined whether wearable devices integrated with the Welloop mobile application and a ligh… | Digital health 2026-07-08 15:43:04 | Source |
| Five-Year Outcomes of Paclitaxel-Coated Balloons in Patients with Dia… test of walk · PMID 42416524 | Myopathies | Thérapie génique | Publication | PubMed | Voir la publication source Long-term outcomes of paclitaxel-coated drug-coated balloons (DCBs) in patients with diabetes mellitus (DM) and infrain… | Vascular health and risk management 2026-07-08 15:43:04 | Source |
| Disparities in deworming coverage between children with and without d… COVID-19 Pandemic and Parents of Disabled Children · PMID 42264499 | Myopathies | Ralentissement de la progression | Publication | PubMed | Voir la publication source Children with disabilities experience lower school enrolment rates and may be systematically excluded from school-based… | BMJ global health 2026-07-08 12:06:58 | Source |
| Neurodevelopmental treatment needs after severe acute respiratory syn… COVID-19 Pandemic and Parents of Disabled Children · PMID 42050906 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source ObjectiveThis cohort study examined whether documented coronavirus disease 2019 in young children affects the need for… | The Journal of international medical research 2026-07-08 12:06:58 | Source |
| Aquatic training improves muscle strength and functional mobility in… Manual muscular test · PMID 42398272 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Myotonic dystrophy type 1 (DM1) is the most common adult muscular dystrophy and is characterized by progressive muscle… | Neuromuscular disorders : NMD 2026-07-08 12:06:57 | Source |
Exploration — prudence
Pistes exploratoires 6
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| N-PPG N-PPG — modulation métabolique cérébrale | Myopathies | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation métabolique et mitohormèse N-PPG est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être pertinents pour Myopat… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |
| Vecteur Ple389 (ADORA2A) MiniPromoter Ple389 — ciblage striatal | Myopathies | Thérapie génique | Hypothèse exploratoire | Rapprochement automatique non validé | Expression génique ciblée dans les neurones striataux Vecteur Ple389 (ADORA2A) est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être per… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |
| α-Amyrin α-Amyrin — protection mitochondriale | Myopathies | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Protection mitochondriale et modulation de la pathologie Tau α-Amyrin est étudié dans Maladie d’Alzheimer et documente plusieurs axes biologiques pouvant être pertinents pour Myopa… | Rapprochement Biomedical Watch · Maladie d’Alzheimer | Détail |
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Myopathies | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation immunométabolique de la microglie 4-octyl itaconate et dérivés est étudié dans Sclérose latérale amyotrophique et documente plusieurs axes biologiques po… | Rapprochement Biomedical Watch · Sclérose latérale amy… | Détail |
| Thonningianin A Thonningianin A — neuroprotection anti-amyloïde | Myopathies | Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation du stress oxydatif et des protéines associées à Alzheimer Thonningianin A est étudié dans Maladie d’Alzheimer et documente plusieurs axes biologiques pouvant être pertinents pou… | Rapprochement Biomedical Watch · Maladie d’Alzheimer | Détail |
| Vutiglabridin Vutiglabridin — autophagie et PON2 | Myopathies | Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Activation de PON2 et stimulation de l’autophagie Vutiglabridin est étudié dans Maladie d’Alzheimer et documente plusieurs axes biologiques pouvant être pertinents pour… | Rapprochement Biomedical Watch · Maladie d’Alzheimer | Détail |