Vue transversale de la maladie
Myopathies
Un même point d’entrée pour les études cliniques, les découvertes scientifiques, les publications et les pistes exploratoires présentes dans Biomedical Watch.
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1028 résultats correspondants
· 46 visibles sur cette page
dans le périmètre Myopathies
Niveau clinique
Études et traitements 434
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Yoomi Physical Therapy Software NCT05815017 · YOOMI: Effect of Gamified Physical Therapy Exercise Software on Inpatient Mobili… | Myopathies | À vérifier | Non applicable | COMPLETED | Patients admitted to the hospital often develop functional impairments due… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:35 | Détail |
| 3 Year Follow up on ANO5 Patients NCT05206617 · NCT05206617 | Myopathies | Ralentissement de la progression | À vérifier | ACTIVE_NOT_RECRUITING | The aim of the study is to investigate progression in muscle affection in… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| ANO5 MRI — MRI-phenotyping of Patients With Pathogenic Anoctamin 5 Va… NCT05102799 · NCT05102799 | Myopathies | Thérapie génique | À vérifier | ACTIVE_NOT_RECRUITING | A large cohort of MRI scans from patients with pathogenic variants in the… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| Apitegromab NCT07435129 · Phase 2 Study Evaluating Apitegromab for the Treatment of FSHD | Myopathies | À vérifier | Phase 2 | RECRUITING | A randomized Phase 2 study to evaluate the efficacy and safety of apitegro… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| Botulinum toxin type A NCT07758322 · Efficacy of Focused Shock Wave Therapy Before and After Botulinum Toxin Injectio… | Myopathies | Traitement symptomatique | Non applicable | ACTIVE_NOT_RECRUITING | The main purpose of this study is to determine which is the best dose of a… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| Constant Current Stimulator NCT07715006 · Dorsal Root Electrical Stimulation in Children With Cerebral Palsy | Myopathies | Traitement symptomatique | Non applicable | RECRUITING | The goal of this clinical trial is to evaluate whether dorsal root electri… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| Conventional Stabilization Splints NCT07760428 · Comparison of Conventional,3D Printed and Novel Hybrid Stabilization Splints in… | Myopathies | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | Occlusal splint therapy is a well-established conservative approach for th… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| delpacibart zotadirsen NCT07250737 · Managed Access Program for Del-zota in Participants With DMD Mutations Amenable… | Myopathies | À vérifier | À vérifier | AVAILABLE | The purpose of this Managed Access Program is to allow access to delpaciba… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| DNA Methylation in PMR NCT07748195 · NCT07748195 | Myopathies | À vérifier | À vérifier | NOT_YET_RECRUITING | Polymyalgia Rheumatica (PMR) is treated with corticosteroids; however, lon… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| Dry Needling NCT07321483 · Reflex Therapy of Temporomandibular Dysfunctions | Myopathies | Traitement symptomatique | Non applicable | RECRUITING | This randomized clinical trial will aim to compare the effectiveness of dr… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| Dual-task cycling NCT07580365 · VirtualPark_Pediatric | Myopathies | À vérifier | Non applicable | RECRUITING | The goal of this clinical trial is to assess the effects of a dual-task, m… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| Effects of Curcumin-Piperine Supplementation in Fibromyalgia NCT07753018 · NCT07753018 | Myopathies | Neuroprotection · Immunomodulation · Traitement symptomatique | Phase 2 | NOT_YET_RECRUITING | The goal of this clinical trail is to evaluate the effectiveness and safet… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| Effects of Pilates and Desk-Based Exercise on Office Workers NCT07763925 · NCT07763925 | Myopathies | Traitement symptomatique | Non applicable | COMPLETED | This study evaluated whether adding Pilates exercises to a desk-based exer… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| EXCEL — A Study to Check Liver Health in Boys With XLMTM, a Serious G… NCT06581146 · NCT06581146 | Myopathies | Traitement symptomatique · Thérapie génique | À vérifier | RECRUITING | XLMTM (X-linked myotubular myopathy) is a serious genetic muscle condition… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| Fibromyalgia Syndrome on Anthropometric and Ultrasonographic Measurem… NCT06536894 · NCT06536894 | Myopathies | À vérifier | À vérifier | COMPLETED | Obstructive type sleep apnea syndrome is a clinical condition characterize… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| GRT6019 NCT07347548 · A Trial to Investigate the Safety and Pharmacokinetics of GRT6019 in Healthy Mal… | Myopathies | À vérifier | Phase 1 | COMPLETED | The purpose of this trial is to assess the safety, tolerability, and PK of… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| HD-tDCS treatments NCT04606095 · Explosive Synchronization of Brain Network Activity in Chronic Pain | Myopathies | Traitement symptomatique | Non applicable | ACTIVE_NOT_RECRUITING | This project is being conducted to evaluate the impact of explosive synchr… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| INFLAME-BANK — Inflammatory Disease Biobank for Immunophenotyping and… NCT07737470 · NCT07737470 | Myopathies | Immunomodulation · Thérapie génique | À vérifier | NOT_YET_RECRUITING | INFLAME-BANK is a French multicenter prospective observational ancillary s… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| KER-065 NCT07704099 · Safety and Efficacy of KER-065 in Participants With Duchenne Muscular Dystrophy | Myopathies | À vérifier | Phase 2 | NOT_YET_RECRUITING | The purpose of this study is to evaluate the safety, tolerability, pharmac… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| KinesioTape — The Effect of KT on Tissue Parameters NCT06012305 · NCT06012305 | Myopathies | Traitement symptomatique | Non applicable | COMPLETED | Myofascial pain is a concept that refers to pain from trigger points. The… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
Découverte scientifique
Recherches et trouvailles 0
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune trouvaille ne correspond aux filtres. | |||||||
Bibliographie
Publications 588
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| A mobile learning environment: a preliminary study of a developmental… test of walk · PMID 42485077 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source An embodied theory of development views an infant's mobility as a causal factor in their cognitive, language and motor… | Disability and rehabilitation. Assistive technology 2026-07-22 21:22:37 | Source |
| Feasibility of Real-Time Autonomous Functional Electrical Stimulation… test of walk · PMID 42484421 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source Freezing of gait is a debilitating walking disturbance that can severely worsen quality of life for people with Parkins… | The European journal of neuroscience 2026-07-22 21:22:37 | Source |
| Persistent hiccups following endobronchial ultrasound-guided transbro… baclofen · PMID 42471910 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a minimally invasive diagnostic procedu… | Respiratory medicine case reports 2026-07-22 21:22:33 | Source |
| Six approved drugs for alcohol use disorder: algorithms for their use… baclofen · PMID 42476146 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source The pharmacological management of alcohol use disorder (AUD) currently includes six medications approved by different r… | Alcohol and alcoholism (Oxford, Oxfordshire) 2026-07-22 21:22:33 | Source |
| Beyond intraocular pressure: vascular and metabolic modifiers of opti… Metformin · PMID 42484773 | Myopathies | Ralentissement de la progression · Thérapie génique | Publication | PubMed | Voir la publication source To critically integrate epidemiological, mechanistic, and clinical evidence linking systemic blood pressure dysregulati… | International ophthalmology 2026-07-22 21:21:06 | Source |
| Case Report: Early-onset euglycemic diabetic ketoacidosis following h… Metformin · PMID 42483676 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source Sodium-glucose cotransporter 2 (SGLT2) inhibitors are associated with euglycemic diabetic ketoacidosis (euDKA), typical… | Frontiers in endocrinology 2026-07-22 21:21:06 | Source |
| Interim Safety Profile From the Feasibility Study of the BrainGate Ne… BrainGate Neural Interface System · PMID 36639237 | Myopathies | Ralentissement de la progression | Publication | PubMed | Voir la publication source Brain-computer interfaces (BCIs) are being developed to restore mobility, communication, and functional independence to… | Neurology 2026-07-18 15:48:46 | Source |
| Neural Point-and-Click Communication by a Person With Incomplete Lock… BrainGate Neural Interface System · PMID 25385765 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source A goal of brain-computer interface research is to develop fast and reliable means of communication for individuals with… | Neurorehabilitation and neural repair 2026-07-18 15:48:46 | Source |
| Multimodality Risk Stratification in Athletes With Long QT Syndrome. Mexiletine · PMID 42460964 | Myopathies | Thérapie génique | Publication | PubMed | Voir la publication source Long QT syndrome has traditionally led to exercise restriction due to concerns for exertion-triggered arrhythmia and su… | JACC. Case reports 2026-07-18 15:48:44 | Source |
| Efficacy of perifracture site injections for pain control following d… GenPHSat injection (Efficacy) · PMID 42469861 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source Surgical site analgesic injections are used as part of multimodal analgesia in elective orthopedic surgery, but their e… | Journal of orthopaedic surgery and research 2026-07-18 15:48:08 | Source |
| Denecimig (Mim8) prophylaxis once-every-2-weeks for hemophilia A with… GenPHSat injection (Safety) · PMID 42469164 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Denecimig (Mim8) is a next-generation, activated factor VIII mimetic, fully human bispecific IgG4 antibody in developme… | Blood advances 2026-07-18 15:48:07 | Source |
| Long-term efficacy and safety of intra-articular corticosteroid injec… GenPHSat injection (Safety) · PMID 42470097 | Myopathies | Ralentissement de la progression · Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Knee osteoarthritis (KOA) is a highly prevalent condition worldwide, resulting in a significant symptom burden and dimi… | Expert opinion on drug safety 2026-07-18 15:48:07 | Source |
| Examining the feasibility and preliminary effects of resistance exerc… Creatine Monohydrate · PMID 42455839 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source The purpose of this trial was to assess the feasibility, acceptability and safety of a 10-week hybrid (in-clinic and vi… | PloS one 2026-07-18 15:48:05 | Source |
| A case report of Good syndrome: Diarrhea and dyspnea. IvIg · PMID 42470030 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Good syndrome (GS) is a rare acquired immunodeficiency disorder characterized by thymoma, hypogammaglobulinemia, and pe… | Medicine 2026-07-18 15:47:59 | Source |
| Knowledge graph visualization and bibliometric analysis of research o… IvIg · PMID 42470076 | Myopathies | Thérapie génique | Publication | PubMed | Voir la publication source Coronary artery lesions (CAL) complicating Kawasaki disease (KD) are a central concern affecting the long-term cardiova… | Medicine 2026-07-18 15:47:59 | Source |
| Evaluation of the "Los Filabres" Protocol on Behavioral and Psycholog… Behavioral Interventions for Controlling Oral Behaviors · PMID 42450944 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source Behavioral and psychological symptoms of dementia (BPSD) are highly prevalent among nursing home residents and represen… | Healthcare (Basel, Switzerland) 2026-07-18 15:47:58 | Source |
| Linguistical and psychometric validation of the MIND Youth Questionna… Behavioral Interventions for Controlling Oral Behaviors · PMID 42449006 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source The Mind Youth Questionnaire is a multidimensional health-related quality-of-life questionnaire designed for pediatric… | Journal of patient-reported outcomes 2026-07-18 15:47:58 | Source |
| Adrenal rather than central dysfunction limits HPA axis recovery afte… Chronic Corticosteroid Therapy · PMID 42464759 | Myopathies | Thérapie génique | Publication | PubMed | Voir la publication source Glucocorticoid-induced adrenal insufficiency (GIAI) can persist for months after discontinuation of chronic corticoster… | Endocrinology 2026-07-18 15:47:55 | Source |
| Erectile dysfunction severity and penile Doppler findings in pelvic f… Tadalafil · PMID 42465782 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Erectile dysfunction (ED) is a common and multifactorial complication after pelvic fracture urethral injury (PFUI), yet… | Indian journal of urology : IJU : journal of the Urolo… 2026-07-18 15:47:51 | Source |
| Targeting canonical TGFβ/SMAD3 and ERK1/2 signaling in human valve in… Tadalafil · PMID 42461450 | Myopathies | Ralentissement de la progression · Immunomodulation | Publication | PubMed | Voir la publication source Rheumatic heart disease (RHD) is a chronic sequel of acute rheumatic fever characterized by sustained inflammation, fib… | Journal of physiology and biochemistry 2026-07-18 15:47:51 | Source |
Exploration — prudence
Pistes exploratoires 6
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| N-PPG N-PPG — modulation métabolique cérébrale | Myopathies | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation métabolique et mitohormèse N-PPG est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être pertinents pour Myopat… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |
| Vecteur Ple389 (ADORA2A) MiniPromoter Ple389 — ciblage striatal | Myopathies | Thérapie génique | Hypothèse exploratoire | Rapprochement automatique non validé | Expression génique ciblée dans les neurones striataux Vecteur Ple389 (ADORA2A) est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être per… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |
| α-Amyrin α-Amyrin — protection mitochondriale | Myopathies | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Protection mitochondriale et modulation de la pathologie Tau α-Amyrin est étudié dans Maladie d’Alzheimer et documente plusieurs axes biologiques pouvant être pertinents pour Myopa… | Rapprochement Biomedical Watch · Maladie d’Alzheimer | Détail |
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Myopathies | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation immunométabolique de la microglie 4-octyl itaconate et dérivés est étudié dans Sclérose latérale amyotrophique et documente plusieurs axes biologiques po… | Rapprochement Biomedical Watch · Sclérose latérale amy… | Détail |
| Thonningianin A Thonningianin A — neuroprotection anti-amyloïde | Myopathies | Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation du stress oxydatif et des protéines associées à Alzheimer Thonningianin A est étudié dans Maladie d’Alzheimer et documente plusieurs axes biologiques pouvant être pertinents pou… | Rapprochement Biomedical Watch · Maladie d’Alzheimer | Détail |
| Vutiglabridin Vutiglabridin — autophagie et PON2 | Myopathies | Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Activation de PON2 et stimulation de l’autophagie Vutiglabridin est étudié dans Maladie d’Alzheimer et documente plusieurs axes biologiques pouvant être pertinents pour… | Rapprochement Biomedical Watch · Maladie d’Alzheimer | Détail |