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Myopathies
Un même point d’entrée pour les études cliniques, les découvertes scientifiques, les publications et les pistes exploratoires présentes dans Biomedical Watch.
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1028 résultats correspondants
· 46 visibles sur cette page
dans le périmètre Myopathies
Niveau clinique
Études et traitements 434
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Yoomi Physical Therapy Software NCT05815017 · YOOMI: Effect of Gamified Physical Therapy Exercise Software on Inpatient Mobili… | Myopathies | À vérifier | Non applicable | COMPLETED | Patients admitted to the hospital often develop functional impairments due… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:35 | Détail |
| 3 Year Follow up on ANO5 Patients NCT05206617 · NCT05206617 | Myopathies | Ralentissement de la progression | À vérifier | ACTIVE_NOT_RECRUITING | The aim of the study is to investigate progression in muscle affection in… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| ANO5 MRI — MRI-phenotyping of Patients With Pathogenic Anoctamin 5 Va… NCT05102799 · NCT05102799 | Myopathies | Thérapie génique | À vérifier | ACTIVE_NOT_RECRUITING | A large cohort of MRI scans from patients with pathogenic variants in the… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| Apitegromab NCT07435129 · Phase 2 Study Evaluating Apitegromab for the Treatment of FSHD | Myopathies | À vérifier | Phase 2 | RECRUITING | A randomized Phase 2 study to evaluate the efficacy and safety of apitegro… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| Botulinum toxin type A NCT07758322 · Efficacy of Focused Shock Wave Therapy Before and After Botulinum Toxin Injectio… | Myopathies | Traitement symptomatique | Non applicable | ACTIVE_NOT_RECRUITING | The main purpose of this study is to determine which is the best dose of a… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| Constant Current Stimulator NCT07715006 · Dorsal Root Electrical Stimulation in Children With Cerebral Palsy | Myopathies | Traitement symptomatique | Non applicable | RECRUITING | The goal of this clinical trial is to evaluate whether dorsal root electri… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| Conventional Stabilization Splints NCT07760428 · Comparison of Conventional,3D Printed and Novel Hybrid Stabilization Splints in… | Myopathies | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | Occlusal splint therapy is a well-established conservative approach for th… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| delpacibart zotadirsen NCT07250737 · Managed Access Program for Del-zota in Participants With DMD Mutations Amenable… | Myopathies | À vérifier | À vérifier | AVAILABLE | The purpose of this Managed Access Program is to allow access to delpaciba… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| DNA Methylation in PMR NCT07748195 · NCT07748195 | Myopathies | À vérifier | À vérifier | NOT_YET_RECRUITING | Polymyalgia Rheumatica (PMR) is treated with corticosteroids; however, lon… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| Dry Needling NCT07321483 · Reflex Therapy of Temporomandibular Dysfunctions | Myopathies | Traitement symptomatique | Non applicable | RECRUITING | This randomized clinical trial will aim to compare the effectiveness of dr… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| Dual-task cycling NCT07580365 · VirtualPark_Pediatric | Myopathies | À vérifier | Non applicable | RECRUITING | The goal of this clinical trial is to assess the effects of a dual-task, m… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| Effects of Curcumin-Piperine Supplementation in Fibromyalgia NCT07753018 · NCT07753018 | Myopathies | Neuroprotection · Immunomodulation · Traitement symptomatique | Phase 2 | NOT_YET_RECRUITING | The goal of this clinical trail is to evaluate the effectiveness and safet… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| Effects of Pilates and Desk-Based Exercise on Office Workers NCT07763925 · NCT07763925 | Myopathies | Traitement symptomatique | Non applicable | COMPLETED | This study evaluated whether adding Pilates exercises to a desk-based exer… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| EXCEL — A Study to Check Liver Health in Boys With XLMTM, a Serious G… NCT06581146 · NCT06581146 | Myopathies | Traitement symptomatique · Thérapie génique | À vérifier | RECRUITING | XLMTM (X-linked myotubular myopathy) is a serious genetic muscle condition… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| Fibromyalgia Syndrome on Anthropometric and Ultrasonographic Measurem… NCT06536894 · NCT06536894 | Myopathies | À vérifier | À vérifier | COMPLETED | Obstructive type sleep apnea syndrome is a clinical condition characterize… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| GRT6019 NCT07347548 · A Trial to Investigate the Safety and Pharmacokinetics of GRT6019 in Healthy Mal… | Myopathies | À vérifier | Phase 1 | COMPLETED | The purpose of this trial is to assess the safety, tolerability, and PK of… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| HD-tDCS treatments NCT04606095 · Explosive Synchronization of Brain Network Activity in Chronic Pain | Myopathies | Traitement symptomatique | Non applicable | ACTIVE_NOT_RECRUITING | This project is being conducted to evaluate the impact of explosive synchr… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| INFLAME-BANK — Inflammatory Disease Biobank for Immunophenotyping and… NCT07737470 · NCT07737470 | Myopathies | Immunomodulation · Thérapie génique | À vérifier | NOT_YET_RECRUITING | INFLAME-BANK is a French multicenter prospective observational ancillary s… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| KER-065 NCT07704099 · Safety and Efficacy of KER-065 in Participants With Duchenne Muscular Dystrophy | Myopathies | À vérifier | Phase 2 | NOT_YET_RECRUITING | The purpose of this study is to evaluate the safety, tolerability, pharmac… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| KinesioTape — The Effect of KT on Tissue Parameters NCT06012305 · NCT06012305 | Myopathies | Traitement symptomatique | Non applicable | COMPLETED | Myofascial pain is a concept that refers to pain from trigger points. The… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
Découverte scientifique
Recherches et trouvailles 0
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune trouvaille ne correspond aux filtres. | |||||||
Bibliographie
Publications 588
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| A Randomized Controlled Trial of Dual Upper-Extremity Training [DUET]… HD-tDCS treatments · PMID 42438177 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source Corticobasal syndrome (CBS) is a progressive neurodegenerative condition characterized by asymmetric limb rigidity, apr… | Movement disorders clinical practice 2026-08-13 15:03:23 | Source |
| Estimating the Minimal Detectable Change (MDC) of the Disability of t… Focal Extracorporeal Shock Wave Therapy (ESWT) · PMID 42526637 | Myopathies | Ralentissement de la progression · Traitement symptomatique | Publication | PubMed | Voir la publication source Idiopathic frozen shoulder is a disabling condition characterized by pain and restricted range of motion, often evaluat… | Orthopaedics & traumatology, surgery & research : OTSR 2026-08-13 15:03:22 | Source |
| Extracorporeal shockwave therapy in tissue repair and regeneration. Focal Extracorporeal Shock Wave Therapy (ESWT) · PMID 42525197 | Myopathies | Remyélinisation indirecte / réparation · Thérapie cellulaire | Publication | PubMed | Voir la publication source In this article, we aim to provide a comprehensive overview of the development of shockwave therapy in medicine, from t… | Wiener medizinische Wochenschrift (1946) 2026-08-13 15:03:22 | Source |
| Identifying the Diagnostic Challenges and Indicators of Orthostatic T… Data Collection of Standard Care of Patients in the EMG Section · PMID 40265716 | Myopathies | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source The diagnosis of orthostatic tremor (OT) is challenging because of its non-specific symptoms and a broad range of diffe… | Movement disorders clinical practice 2026-08-13 15:03:20 | Source |
| Utilization of Preoperative Electrodiagnostic Studies for Carpal Tunn… Data Collection of Standard Care of Patients in the EMG Section · PMID 27068003 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Given the lack of a reference standard diagnostic tool for carpal tunnel syndrome (CTS), we conducted a population-leve… | The Journal of hand surgery 2026-08-13 15:03:20 | Source |
| Applicability of an Immersive Virtual Reality Exercise Training Syste… Dual-task cycling · PMID 35878115 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Virtual reality is a computer-generated simulation of a real or imaginary three-dimensional environment that has entere… | Sports (Basel, Switzerland) 2026-08-13 15:03:19 | Source |
| Event-related brain potentials reveal enhancing and compensatory mech… Dual-task cycling · PMID 37845733 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Various neurocognitive tests have shown that cycling enhances cognitive performance compared to resting. Event-related… | BMC sports science, medicine & rehabilitation 2026-08-13 15:03:19 | Source |
| Advancing treatment of spinal muscular atrophy through inhibition of… Apitegromab · PMID 41566720 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source In spinal muscular atrophy (SMA), irreversible loss of spinal motor neurons and progressive skeletal muscle atrophy cau… | Expert review of neurotherapeutics 2026-08-13 15:03:18 | Source |
| Apitegromab for lean mass preservation during tirzepatide-induced wei… Apitegromab · PMID 42260100 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Loss of lean mass in proportion to total weight loss is observed with incretin mimetic therapies such as tirzepatide an… | Nature medicine 2026-08-13 15:03:18 | Source |
| Impact of Virtual Reality-Based Task-Oriented Training for Enhancing… Standard rehabilitation · PMID 42581516 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source BACKGROUND Stroke frequently causes persistent motor impairment and dependence in activities of daily living (ADL). Vir… | Medical science monitor : international medical journa… 2026-08-13 15:03:17 | Source |
| The Role of Radial Shockwave Therapy in Reducing Spasticity and Impro… Standard rehabilitation · PMID 42589983 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source : Spasticity resulting from a stroke usually develops within a few weeks or months of the incident and occurs in approx… | Journal of clinical medicine 2026-08-13 15:03:17 | Source |
| Exploring somatosensory temporal discrimination deficits in rheumatoi… Constant Current Stimulator · PMID 41316482 | Myopathies | Ralentissement de la progression | Publication | PubMed | Voir la publication source Objective- Somatosensory deficits in rheumatoid arthritis (RA) have not been adequately investigated, despite their pot… | Advances in rheumatology (London, England) 2026-08-13 15:03:15 | Source |
| Optimizing Movement Performance with Altered Sensation: An Examinatio… Constant Current Stimulator · PMID 37759903 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Two experiments were conducted to assess the impact of induced paresthesia on movement parameters of goal-directed aimi… | Brain sciences 2026-08-13 15:03:15 | Source |
| Degradation-Robust Hue Prior Network for Low-Light Rainy Image Restor… SRP-1003 SC Injection · PMID 42590629 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Restoring images captured in low-light rainy scenes is challenging because brightness degradation and rain corruption a… | Sensors (Basel, Switzerland) 2026-08-13 15:03:14 | Source |
| Elegans-Inspired Magnetic Polyurethane Soft Robot (MPSR) for Closed V… SRP-1003 SC Injection · PMID 42590852 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Secondary hemorrhage is inevitable during the transportation of casualties in harsh environments, and reoperative treat… | Advanced healthcare materials 2026-08-13 15:03:14 | Source |
| Remifentanil attenuates LPS-induced hepatic injury by modulating NRF2… SRP-1003 IV Infusion · PMID 42584673 | Myopathies | Neuroprotection · Immunomodulation · Thérapie génique | Publication | PubMed | Voir la publication source Lipopolysaccharide (LPS)-induced sepsis causes widespread inflammation and liver dysfunction, driven by oxidative stres… | Naunyn-Schmiedeberg's archives of pharmacology 2026-08-13 15:03:13 | Source |
| Transient Neonatal Myasthenia Gravis in a Newborn Infant Presenting t… SRP-1003 IV Infusion · PMID 42583073 | Myopathies | Thérapie génique | Publication | PubMed | Voir la publication source A four-day-old female born full term via uncomplicated vaginal delivery presented to the emergency department with poor… | Cureus 2026-08-13 15:03:13 | Source |
| AOC 1044 induces exon 44 skipping and restores dystrophin protein in… AOC 1044 · PMID 40183632 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Duchenne muscular dystrophy (DMD) is a severe disorder caused by mutations in the dystrophin gene, resulting in loss of… | Nucleic acids research 2026-08-13 15:03:12 | Source |
| Antibodies to watch in 2026. delpacibart zotadirsen · PMID 41560619 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source The Antibodies to Watch article series provides annual updates on commercial late-stage clinical development, regulator… | mAbs 2026-08-13 15:03:10 | Source |
| A hospital based epidemiological study of genetically determined musc… 3 Year Follow up on ANO5 Patients · PMID 32146000 | Myopathies | Thérapie génique | Publication | PubMed | Voir la publication source We determined the prevalence of genetically determined neuromuscular diseases in adult Norwegian patients from Hordalan… | Neuromuscular disorders : NMD 2026-08-13 15:03:09 | Source |
Exploration — prudence
Pistes exploratoires 6
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| N-PPG N-PPG — modulation métabolique cérébrale | Myopathies | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation métabolique et mitohormèse N-PPG est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être pertinents pour Myopat… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |
| Vecteur Ple389 (ADORA2A) MiniPromoter Ple389 — ciblage striatal | Myopathies | Thérapie génique | Hypothèse exploratoire | Rapprochement automatique non validé | Expression génique ciblée dans les neurones striataux Vecteur Ple389 (ADORA2A) est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être per… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |
| α-Amyrin α-Amyrin — protection mitochondriale | Myopathies | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Protection mitochondriale et modulation de la pathologie Tau α-Amyrin est étudié dans Maladie d’Alzheimer et documente plusieurs axes biologiques pouvant être pertinents pour Myopa… | Rapprochement Biomedical Watch · Maladie d’Alzheimer | Détail |
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Myopathies | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation immunométabolique de la microglie 4-octyl itaconate et dérivés est étudié dans Sclérose latérale amyotrophique et documente plusieurs axes biologiques po… | Rapprochement Biomedical Watch · Sclérose latérale amy… | Détail |
| Thonningianin A Thonningianin A — neuroprotection anti-amyloïde | Myopathies | Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation du stress oxydatif et des protéines associées à Alzheimer Thonningianin A est étudié dans Maladie d’Alzheimer et documente plusieurs axes biologiques pouvant être pertinents pou… | Rapprochement Biomedical Watch · Maladie d’Alzheimer | Détail |
| Vutiglabridin Vutiglabridin — autophagie et PON2 | Myopathies | Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Activation de PON2 et stimulation de l’autophagie Vutiglabridin est étudié dans Maladie d’Alzheimer et documente plusieurs axes biologiques pouvant être pertinents pour… | Rapprochement Biomedical Watch · Maladie d’Alzheimer | Détail |