Vue transversale de la maladie
Migraine
Un même point d’entrée pour les études cliniques, les découvertes scientifiques, les publications et les pistes exploratoires présentes dans Biomedical Watch.
Périmètre
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1239 résultats correspondants
· 46 visibles sur cette page
dans le périmètre Migraine
Niveau clinique
Études et traitements 572
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| ketamine infusion NCT06935552 · Ketamine and Lidocaine Infusion in Refractory Chronic Migraine | Migraine | Ralentissement de la progression · Traitement symptomatique | Phase 1 | NOT_YET_RECRUITING | Ketamine is a drug used for anesthesia but at low doses it is a very effec… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:17 | Détail |
| Ketorolac NCT04353505 · Intra-arterial Sphenopalatine Ganglion Block for Patients With Refractory Headac… | Migraine | À vérifier | Phase 1 | WITHDRAWN | The purpose of this study is to evaluate the safety and efficacy of intra-… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:17 | Détail |
| Lidocaine (drug) NCT07361549 · LIGHT 2 — Localized Injection of Lidocaine Via the Middle Meningeal Artery for I… | Migraine | Traitement symptomatique | Phase 2 | NOT_YET_RECRUITING | The main purpose of this study is to evaluate the effectiveness of a new t… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:17 | Détail |
| Middle Meningeal Artery embolization NCT06029153 · FAST-EM — Efficacy and Safety of Middle Meningeal Artery Embolization for Treatm… | Migraine | À vérifier | Non applicable | COMPLETED | This is a prospective, multi-center, feasibility study to investigate safe… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:17 | Détail |
| Precision NCT00747812 · PRISM UK — Study of Occipital Nerve Stimulation for Drug Refractory Migraine | Migraine | Thérapie génique | Phase 2 | TERMINATED | The purpose of this study is to evaluate the safety and effectiveness of a… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:17 | Détail |
| Precision NCT00286078 · Treatment for Migraines With an Implantable Device | Migraine | Thérapie génique | Non applicable | COMPLETED | The purpose of this study is to evaluate the safety and effectiveness of a… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:17 | Détail |
| Prodigy internal pulse generator occipital nerve stimulator NCT07087678 · Occipital Nerve Stimulation in Chronic Migraine | Migraine | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | The goal of this clinical trial is to compare two different types of occip… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:17 | Détail |
| Propofol NCT02492295 · Low-dose Propofol for the Treatment of Severe Refractory Migraine Headache in th… | Migraine | Immunomodulation · Traitement symptomatique | Non applicable | TERMINATED | Migraine headache is a frequent Emergency Department complaint. While firs… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:17 | Détail |
| Psychological and Biological Markers of Refractory Migraine NCT05046119 · NCT05046119 | Migraine | Traitement symptomatique | À vérifier | UNKNOWN | The term "refractory" migraine describes a particularly aggressive form of… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:17 | Détail |
| pulsed electromagnetic field NCT01670214 · Pulsed Electromagnetic Field Therapy in the Refractory Migraine | Migraine | À vérifier | Non applicable | COMPLETED | Pulsed electromagnetic field (PEMF) as prophylactic treatment may prevent… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:17 | Détail |
| SCS NCT05382832 · BTX/SCS/TMig — Botox Vs Spinal Cord Stimulation in the Treatment of Refractory M… | Migraine | À vérifier | Non applicable | UNKNOWN | The clinical trial is focused on the treatment of selected patients with a… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:17 | Détail |
| Senza™, High Frequency Spinal Cord Stimulator for Refractory Chronic… NCT01653340 · rCM HF-SCS — A Feasibility Clinical Trial to Evaluate High Frequency Spinal Cord… | Migraine | À vérifier | Non applicable | COMPLETED | The purpose of this study is to assess short- and long-term safety, tolera… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:17 | Détail |
| The Use of Autologous Mesenchymal Stem Cell Preparation for Treatment… NCT04064879 · NCT04064879 | Migraine | Traitement symptomatique · Thérapie cellulaire | Non applicable | SUSPENDED | The present study is being undertaken as a phase I study to determine the… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:17 | Détail |
| Transcranial electrical stimulation NCT05099406 · Home-based Transcranial Stimulation in the Treatment of Patients With Refractory… | Migraine | Traitement symptomatique · Thérapie génique | Non applicable | UNKNOWN | Refractory chronic pain represents a serious and limiting health condition… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:17 | Détail |
| Cadwell Cascade 32 PRO NCT07402954 · MMA-Stim — Stimulation of External Carotid Artery Circulation | Migraine | Traitement symptomatique · Thérapie génique | Non applicable | RECRUITING | This study is testing a new approach to help people with migraine headache… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:16 | Détail |
| embolization of middle meningeal arteries NCT07223008 · MMAE-Migraine — Bilateral Embolization of the Middle Meningeal Arteries for Refr… | Migraine | À vérifier | Non applicable | RECRUITING | This study is to test the safety and feasibility of a procedure called emb… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:16 | Détail |
| Pulsed Radiofrequency of the Sphenopalatine Ganglion NCT07370142 · SPG-PRF — Sphenopalatine Ganglion Pulsed Radiofrequency Treatment Outcomes | Migraine | Traitement symptomatique | Non applicable | COMPLETED | Purpose of the Study: This study aims to evaluate the clinical effectivene… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:16 | Détail |
| Amylin NCT07340788 · Amylin-Induced Migraine Attacks Without Aura | Migraine | À vérifier | Non applicable | NOT_YET_RECRUITING | Pramlintide is a peptide analogue of human amylin which is a vasoactive si… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:15 | Détail |
| Discussion on the Mechanism of Acupuncture on Patients with Paroxysma… NCT06676670 · NCT06676670 | Migraine | Thérapie génique | Non applicable | UNKNOWN | Background: Migraine is common but poorly managed with drugs. Acupuncture,… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:15 | Détail |
| FAST — Molecular Phenotyping of Migraine Patients According to Sex an… NCT06674772 · NCT06674772 | Migraine | À vérifier | À vérifier | RECRUITING | Patients will be asked to visit the study center 2 times, the first time f… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:15 | Détail |
Découverte scientifique
Recherches et trouvailles 0
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune trouvaille ne correspond aux filtres. | |||||||
Bibliographie
Publications 661
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Active machine learning model for the dynamic simulation and growth m… TI-001 · PMID 38184678 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Substrate-catalyzed growth offers a highly promising approach for the controlled synthesis of carbon nanostructures. Ho… | Nature communications 2026-08-08 00:59:56 | Source |
| Combined Occipital Nerve and Sphenopalatine Ganglion Neuromodulation… Occipital Nerve Stimulation · PMID 42100751 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Craniofacial complex regional pain syndrome (CRPS) is a rare, diagnostically challenging condition characterized by sym… | Local and regional anesthesia 2026-08-08 00:59:56 | Source |
| Comparative Efficacy and Acceptability of Noninvasive Brain Stimulati… Occipital Nerve Stimulation · PMID 42473074 | Migraine | À vérifier | Publication | PubMed | Voir la publication source This network meta-analysis (NMA) aimed to compare and rank the efficacy and acceptability of different noninvasive brai… | Brain and behavior 2026-08-08 00:59:56 | Source |
| TiO2 nanotubes: interdependence of substrate grain orientation and gr… TI-001 · PMID 25545715 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Highly ordered arrays of TiO2 nanotubes can be produced by self-organized anodic growth. It is desirable to identify ke… | ACS applied materials & interfaces 2026-08-08 00:59:56 | Source |
| International Headache society evidence-based guidelines on the use o… Nerivio Migra-1 Sham device · PMID 41117312 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source ObjectiveTo develop evidence-based clinical practice guidelines for non-invasive neuromodulation devices in acute and p… | Cephalalgia : an international journal of headache 2026-08-08 00:59:54 | Source |
| Plasma Phosphorylated Tau 217 in Participants at Risk for Chronic Tra… BE WELL With Migraine: Brain Education and WELLness With Migraine · PMID 42440317 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source In vivo biomarkers for detecting neuropathologies from repetitive head impacts (RHI), including chronic traumatic encep… | JAMA network open 2026-08-08 00:59:53 | Source |
| Weight loss with atogepant in the long-term treatment of migraine: An… BE WELL With Migraine: Brain Education and WELLness With Migraine · PMID 42396885 | Migraine | À vérifier | Publication | PubMed | Voir la publication source To assess weight loss with atogepant 60 mg once daily during long-term treatment of chronic migraine (CM) and episodic… | Headache 2026-08-08 00:59:53 | Source |
| Cellulose and Its Derivatives in Drug Delivery: Recent Advances and A… sumatriptan succinate · PMID 42198288 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Drug delivery systems have long faced a fundamental challenge: achieving high drug-loading efficiency, precise control… | Pharmaceutics 2026-08-08 00:59:51 | Source |
| Spatial metabolomics combined with MALDI-MSI unveils gut-brain axis m… sumatriptan succinate · PMID 41619552 | Migraine | Immunomodulation · Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Migraine is a highly disabling neurological disorder characterized by recurrent headaches and complex metabolic disturb… | Phytomedicine : international journal of phytotherapy… 2026-08-08 00:59:51 | Source |
| Drugs targeting nitric oxide synthase for migraine treatment. NXN-188 · PMID 24818644 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Ample evidence that nitric oxide (NO) is a causative molecule in migraine has encouraged research to develop drugs that… | Expert opinion on investigational drugs 2026-08-08 00:59:50 | Source |
| The nitric oxide synthase inhibitor and serotonin-receptor agonist NX… NXN-188 · PMID 29913885 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Background and aims NXN-188 is a combined neuronal nitric oxide synthase (nNOS) inhibitor and 5HT-1B/1D receptor agonis… | Scandinavian journal of pain 2026-08-08 00:59:50 | Source |
| Identifying central positional vertigo to prevent diagnostic pitfalls… Vestibular System in Migrainous Vertigo Patients · PMID 42564662 | Migraine | À vérifier | Publication | PubMed | Voir la publication source This case series highlights the critical role of radiological imaging in patients presenting with positional vertigo in… | Radiology case reports 2026-08-08 00:59:48 | Source |
| Quantitative pupillometry as a marker of autonomic dysregulation in v… Vestibular System in Migrainous Vertigo Patients · PMID 42548108 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source Vestibular migraine (VM) has been associated with altered central sensory processing; however, objective measures of au… | Journal of oral & facial pain and headache 2026-08-08 00:59:48 | Source |
| Arterial hepatic perfusion is preserved during early resuscitation af… blood withdrawal · PMID 42431156 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Hemorrhagic shock is a major contributor to morbidity and mortality after polytrauma and plays a central role in the de… | Injury 2026-08-08 00:59:47 | Source |
| Long peripheral catheters for short-term vascular access: A 7-day obs… blood withdrawal · PMID 42438309 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source Long peripheral catheters are increasingly used as an alternative to short peripheral catheters for short-term intraven… | The journal of vascular access 2026-08-08 00:59:47 | Source |
| A Real-World Evidence Study on US Patients Demonstrating Safety of Hi… Nerivio ® · PMID 41886224 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Remote electrical neuromodulation (REN) is an FDA-cleared, nonsignificant-risk, drug-free, prescribed wearable device (… | Pain and therapy 2026-08-08 00:59:45 | Source |
| Association of adverse childhood experiences with physical illness an… Brief Interventions in Chronic Migraine · PMID 40194777 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Adverse childhood experiences (ACEs) are highly prevalent and associated with life-long health consequences. Here, we i… | European journal of public health 2026-08-08 00:59:45 | Source |
| Non-Pharmacological Treatment of Primary Headaches-A Focused Review. Brief Interventions in Chronic Migraine · PMID 37891800 | Migraine | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Headache disorders are a significant global health burden, leading to reduced quality of life. While vast pharmacologic… | Brain sciences 2026-08-08 00:59:45 | Source |
| U.S. Veterans Using Remote Electrical Neuromodulation for Migraine: A… Nerivio ® · PMID 42520312 | Migraine | Ralentissement de la progression · Traitement symptomatique | Publication | PubMed | Voir la publication source Among U.S. veterans, migraine and other headache disorders are common, and frequently co-occur with other comorbidities… | Military medicine 2026-08-08 00:59:45 | Source |
| 2025 guideline update to acute treatment of migraine for adults in th… Greater Occipital Nerve Block with dexamethasone and lidocaine · PMID 41321235 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source To update the 2016 American Headache Society (AHS) guideline on parenteral pharmacologic therapies for the management o… | Headache 2026-08-08 00:59:43 | Source |
Exploration — prudence
Pistes exploratoires 6
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Bavisant BRAVEinMS — Bavisant | Migraine | Remyélinisation · Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Antagonisme du récepteur H3 de l’histamine Bavisant est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migra… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| Tol-MP Tol-MP — tolérance immunitaire spécifique de la myéline | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Microparticules biodégradables chargées en rapamycine et fonctionnalisées… Tol-MP est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migrain… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| C-CAR168 C-CAR168 — AbelZeta Pharma | Migraine | Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | CAR-T autologue bispécifique anti-CD20/BCMA visant une déplétion profonde… C-CAR168 est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migra… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| SetPoint System SetPoint System — SetPoint Medical | Migraine | Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | yClinical EvidenceFAQsManualsScienceFuture ApplicationsPublicationsCompany… SetPoint System est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pou… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation immunométabolique de la microglie 4-octyl itaconate et dérivés est étudié dans Sclérose latérale amyotrophique et documente plusieurs axes biologiques po… | Rapprochement Biomedical Watch · Sclérose latérale amy… | Détail |
| N-PPG N-PPG — modulation métabolique cérébrale | Migraine | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation métabolique et mitohormèse N-PPG est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être pertinents pour Migrai… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |