Vue transversale de la maladie
Myopathies
Un même point d’entrée pour les études cliniques, les découvertes scientifiques, les publications et les pistes exploratoires présentes dans Biomedical Watch.
Périmètre
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1028 résultats correspondants
· 46 visibles sur cette page
dans le périmètre Myopathies
Niveau clinique
Études et traitements 434
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Effectiveness of Tele-Rehabilitation in Managing Rhomboid Trigger Poi… NCT07573527 · NCT07573527 | Myopathies | Ralentissement de la progression · Traitement symptomatique | Non applicable | RECRUITING | This randomized controlled trial aims to assess the effectiveness of tele-… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:34 | Détail |
| Exopulse Mollii Suit NCT05885139 · EXOCEP2GER — Exopulse Mollii Suit, Motor Functions & CP Children With Cerebral P… | Myopathies | Traitement symptomatique | Non applicable | COMPLETED | Cerebral Palsy (CP) is is estimated to be around 1.5-3 per live birth, wit… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:34 | Détail |
| IL1 Inhibition in FOP NCT06724562 · NCT06724562 | Myopathies | Traitement symptomatique | À vérifier | RECRUITING | This is an observational pre-post study to observe if the off label use of… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:34 | Détail |
| Low Level Laser Therapy NCT07753460 · Low-Level Laser Therapy in the Treatment of Trigger Finger | Myopathies | Immunomodulation · Traitement symptomatique | Non applicable | RECRUITING | Trigger finger, also known as stenosing tenosynovitis, is one of the most… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:34 | Détail |
| ME/CFS — Controlled Trial of Hydrogen Water as a Treatment for Myalgi… NCT07753122 · NCT07753122 | Myopathies | Traitement symptomatique | Non applicable | RECRUITING | This is a 16-week controlled treatment trial of an over-the -counter suppl… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:34 | Détail |
| Micro-Fragmented Adipose Tissue (MFAT) injection NCT07748793 · MFAT — Autologous Fat Grafting for the Treatment of Chronic Tendinopathy | Myopathies | Traitement symptomatique · Thérapie génique | Non applicable | NOT_YET_RECRUITING | The goal of this clinical trial is to learn whether a one-time injection o… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:34 | Détail |
| Patient-Centered Assessment of Symptoms and Outcomes NCT03952624 · NCT03952624 | Myopathies | Traitement symptomatique | À vérifier | ACTIVE_NOT_RECRUITING | Background: The cause of fatigue is not well understood. It can be felt di… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:34 | Détail |
| RCT — The Effect of Multimodal Approach of Electrotherapy Versus Shoc… NCT07750080 · NCT07750080 | Myopathies | Traitement symptomatique | Non applicable | RECRUITING | Tennis Elbow (or Lateral Epicondylalgia) is one of the most common overloa… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:34 | Détail |
| Study of Intramuscular Injections of OnabotulinumtoxinA to Assess Cha… NCT06150729 · NCT06150729 | Myopathies | Traitement symptomatique | À vérifier | COMPLETED | Spasticity is often observed as muscle tightness and stiffness in the uppe… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:34 | Détail |
| TMD — The Effects of Pilates Exercises on Women With Myogenic Temporo… NCT07750145 · NCT07750145 | Myopathies | Ralentissement de la progression · Traitement symptomatique | Non applicable | COMPLETED | The aim of this study is to investigate the effects of an 8-week Pilates e… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:34 | Détail |
| TSK-TMD-ITA — The Italian Version of the Tampa Scale for Kinesiophobi… NCT07750509 · NCT07750509 | Myopathies | Ralentissement de la progression · Traitement symptomatique · Thérapie génique | À vérifier | NOT_YET_RECRUITING | This observational, cross-sectional study aims to translate, culturally ad… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:34 | Détail |
| Ultrasound-guided dry needling NCT07550322 · Dry Needling vs ESWT in Lateral Epicondylitis | Myopathies | Traitement symptomatique | Non applicable | ACTIVE_NOT_RECRUITING | This randomized single-blind controlled trial aims to compare the effectiv… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:34 | Détail |
| Using Personalized Rehabilitation to Reduce Disease and Increase Acti… NCT07749547 · NCT07749547 | Myopathies | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | Polymyalgia rheumatica (PMR) is a condition that causes joint pain and sti… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:34 | Détail |
| Vagus nerve stimulation NCT06237595 · Vagus Nerve Stimulation in Fibromyalgia | Myopathies | À vérifier | Non applicable | COMPLETED | Vagus nerve stimulation is thought to reduce sympathetic nerve outflow and… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:34 | Détail |
| AOC-1020 NCT07038200 · FORTITUDE-3 — A Study to Evaluate Del-brax (Also Referred to as AOC 1020) in Par… | Myopathies | À vérifier | Phase 3 | RECRUITING | A Randomized, Double-blind, Placebo-controlled, Phase 3 Study to Evaluate… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:36 | Détail |
| AOC 1044 NCT06244082 · EXPLORE44OLE — Ph2 Open-label Study of AOC 1044 in Duchenne Muscular Dystrophy P… | Myopathies | À vérifier | Phase 2 | ACTIVE_NOT_RECRUITING | A Randomized, Double-blind, Placebo-controlled, Phase 3 Study to Evaluate… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:36 | Détail |
| BBP-418 NCT04800874 · Study of BBP-418 in Patients With LGMD2I | Myopathies | À vérifier | Phase 2 | ACTIVE_NOT_RECRUITING | BBP-418 is being developed for the treatment of patients with Limb-Girdle… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:36 | Détail |
| BMN 351 NCT07573631 · An Open-Label Extension Study to Evaluate the Long-term Safety and Efficacy of B… | Myopathies | À vérifier | Phase 2 | ENROLLING_BY_INVITATION | This open-label extension study aims to evaluate the long-term safety and… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:36 | Détail |
| CDLink — CureDuchenne Link®: A Resource for Research NCT04972604 · NCT04972604 | Myopathies | À vérifier | À vérifier | COMPLETED | CureDuchenne link is a data hub comprised of integrated biospecimens, clin… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:36 | Détail |
| Del-desiran (AOC 1001) NCT07008469 · HARBOR-OLE — Global Open-Label Extension Study of Del-desiran for the Treatment… | Myopathies | À vérifier | Phase 3 | ENROLLING_BY_INVITATION | A Global Phase 3 Open-Label Extension Study to Assess the Long-Term Safety… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:36 | Détail |
Découverte scientifique
Recherches et trouvailles 0
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune trouvaille ne correspond aux filtres. | |||||||
Bibliographie
Publications 588
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Unlocking hypoglycemic effect of black highland barley by targeting α… (-)-Epicatechin · PMID 42177877 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Highland barley is a unique crop of the Qinghai-Tibet Plateau, and its hypoglycemic properties have attracted extensive… | Talanta 2026-08-16 13:25:58 | Source |
| Anaesthetic efficacy of intraligamentary injection compared to incisi… Mepivacaine Hydrochloride · PMID 39825316 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source In dentistry, local anesthetic is frequently used to manage pain throughout several phases of dental treatments, includ… | BMC oral health 2026-08-16 13:25:54 | Source |
| Lidocaine spray vs mepivacaine local infiltration for suturing 1st/2n… Mepivacaine Hydrochloride · PMID 38914976 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Perineal lacerations are a very common complication of post-partum. Usually, the repair of 1st and 2nd-grade laceration… | BMC pregnancy and childbirth 2026-08-16 13:25:54 | Source |
| The efficacy of injecting a distillate of the pitcher plant (Sarracen… Mepivacaine Hydrochloride · PMID 38145776 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source This study aimed to determine the efficacy of instilling extract of the pitcher plant around the palmar digital nerves… | Journal of equine veterinary science 2026-08-16 13:25:54 | Source |
| Comparison between Perineural and Intravenous Dexamethasone on Durati… Lidocaine Hydrochloride · PMID 41574836 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source A disadvantage of regional blocks is their limited period of efficacy. One of the medications that has been found to ha… | Annals of African medicine 2026-08-16 13:25:53 | Source |
| Topical delivery of Lidocaine using spicules for local anesthesia. Lidocaine Hydrochloride · PMID 41402578 | Myopathies | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Topical anesthesia offers a painless alternative to injections but is limited by the low skin permeability of local ane… | Drug delivery and translational research 2026-08-16 13:25:53 | Source |
| Efficacy of dry needling in reducing spasticity after stroke: A syste… Dry Needling · PMID 42603654 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source To assess the effectiveness of dry needling (DN) in reducing spasticity among post-stroke patients through meta-analysi… | Complementary therapies in medicine 2026-08-16 13:25:50 | Source |
| Interventional Procedures in Sports. Dry Needling · PMID 42547150 | Myopathies | Immunomodulation · Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Image-guided percutaneous procedures are increasingly important in managing sports-related overuse and degenerative inj… | Radiologic clinics of North America 2026-08-16 13:25:50 | Source |
| Operational taxonomy as a determinant of classification stability in… Dry Needling · PMID 42235437 | Myopathies | Neuroprotection | Publication | PubMed | Voir la publication source Reproducibility in rehabilitation evidence synthesis is influenced not only by search strategy and adjudication archite… | International journal of medical informatics 2026-08-16 13:25:50 | Source |
| CACNA1C -Related Channelopathy Presenting With Adult-Onset Combined D… Xeomin Injectable Product · PMID 41978253 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source Pathogenic variants in CACNA1C have been associated with cardiac arrhythmias and neurodevelopmental disorders, occasion… | American journal of medical genetics. Part A 2026-08-16 13:25:47 | Source |
| Late recovery of responsiveness after intra-thecal baclofen pump impl… infusion pump for intrathecal baclofen, Synchromed, Medtronic · PMID 31267188 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source Patients with a prolonged disorder of consciousness (DoC) may present with severe spasticity and diffuse pain, which mi… | Acta neurochirurgica 2026-08-16 13:25:46 | Source |
| Wearable sensors in paediatric neurology. Syde · PMID 39888848 | Myopathies | Ralentissement de la progression · Thérapie génique | Publication | PubMed | Voir la publication source Wearable sensors have the potential to transform diagnosis, monitoring, and management of children who have neurologica… | Developmental medicine and child neurology 2026-08-16 13:25:41 | Source |
| Effects of carnosine supplementation on physical endurance: a placebo… Physical therapy · PMID 42308284 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Carnosine (β-alanine-L-histidine) is an endogenous dipeptide found in abundance in highly metabolic tissues such as ske… | Journal of the International Society of Sports Nutriti… 2026-08-16 13:25:37 | Source |
| Learning from Inuit perspectives on timimut ikajuqsivik/rehabilitatio… Physical therapy · PMID 42409750 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source The practice approaches and evidence base of timimut ikajuqtiit/rehabilitation professionals working with children are… | International journal of circumpolar health 2026-08-16 13:25:37 | Source |
| Instant analgesic effect of radial extracorporeal shock wave therapy… sham shockwave therapy · PMID 32046753 | Myopathies | Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source Primary dysmenorrhoea (PDM) is defined as a series of pain-dominated symptoms during and after menstruation without org… | Trials 2026-08-16 13:25:36 | Source |
| Association between radial extracorporeal shock wave therapy combined… Radial extracorporeal shock wave therapy (rESWT) · PMID 42264811 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source Few studies have evaluated the combined effects of radial extracorporeal shock wave therapy (rESWT) and physical therap… | Journal of bodywork and movement therapies 2026-08-16 13:25:33 | Source |
| [Translated article] Short- and mid-term efficacy of extracorporeal s… Radial extracorporeal shock wave therapy (rESWT) · PMID 42023623 | Myopathies | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Trigger finger is a common condition managed through various conservative approaches. This study aimed to compare the s… | Revista espanola de cirugia ortopedica y traumatologia 2026-08-16 13:25:33 | Source |
| A matrix-adapted RNA extraction strategy for targeted RT-qPCR analysi… RNA extraction · PMID 42548905 | Myopathies | Thérapie génique | Publication | PubMed | Voir la publication source Human amniotic membrane (HAM) is a promising scaffold for periodontal tissue engineering, supporting favorable cellular… | Regenerative therapy 2026-08-16 13:25:30 | Source |
| Optimizing protocols for microRNA profiling of infant and toddler sto… RNA extraction · PMID 41715892 | Myopathies | Thérapie génique | Publication | PubMed | Voir la publication source Despite growing interest in profiling microRNAs (miRNAs) in infant and toddler stool, no studies have compared protocol… | RNA biology 2026-08-16 13:25:30 | Source |
| Salivary RANKL and OPG gene expression quantification during intermax… RNA extraction · PMID 42318067 | Myopathies | Thérapie génique | Publication | PubMed | Voir la publication source This protocol describes a non-invasive workflow for quantifying salivary RANKL and OPG gene expression in orthodontic p… | MethodsX 2026-08-16 13:25:30 | Source |
Exploration — prudence
Pistes exploratoires 6
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| N-PPG N-PPG — modulation métabolique cérébrale | Myopathies | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation métabolique et mitohormèse N-PPG est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être pertinents pour Myopat… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |
| Vecteur Ple389 (ADORA2A) MiniPromoter Ple389 — ciblage striatal | Myopathies | Thérapie génique | Hypothèse exploratoire | Rapprochement automatique non validé | Expression génique ciblée dans les neurones striataux Vecteur Ple389 (ADORA2A) est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être per… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |
| α-Amyrin α-Amyrin — protection mitochondriale | Myopathies | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Protection mitochondriale et modulation de la pathologie Tau α-Amyrin est étudié dans Maladie d’Alzheimer et documente plusieurs axes biologiques pouvant être pertinents pour Myopa… | Rapprochement Biomedical Watch · Maladie d’Alzheimer | Détail |
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Myopathies | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation immunométabolique de la microglie 4-octyl itaconate et dérivés est étudié dans Sclérose latérale amyotrophique et documente plusieurs axes biologiques po… | Rapprochement Biomedical Watch · Sclérose latérale amy… | Détail |
| Thonningianin A Thonningianin A — neuroprotection anti-amyloïde | Myopathies | Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation du stress oxydatif et des protéines associées à Alzheimer Thonningianin A est étudié dans Maladie d’Alzheimer et documente plusieurs axes biologiques pouvant être pertinents pou… | Rapprochement Biomedical Watch · Maladie d’Alzheimer | Détail |
| Vutiglabridin Vutiglabridin — autophagie et PON2 | Myopathies | Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Activation de PON2 et stimulation de l’autophagie Vutiglabridin est étudié dans Maladie d’Alzheimer et documente plusieurs axes biologiques pouvant être pertinents pour… | Rapprochement Biomedical Watch · Maladie d’Alzheimer | Détail |