Vue transversale de la maladie
Myopathies
Un même point d’entrée pour les études cliniques, les découvertes scientifiques, les publications et les pistes exploratoires présentes dans Biomedical Watch.
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1028 résultats correspondants
· 46 visibles sur cette page
dans le périmètre Myopathies
Niveau clinique
Études et traitements 434
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Effectiveness of Tele-Rehabilitation in Managing Rhomboid Trigger Poi… NCT07573527 · NCT07573527 | Myopathies | Ralentissement de la progression · Traitement symptomatique | Non applicable | RECRUITING | This randomized controlled trial aims to assess the effectiveness of tele-… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:34 | Détail |
| Exopulse Mollii Suit NCT05885139 · EXOCEP2GER — Exopulse Mollii Suit, Motor Functions & CP Children With Cerebral P… | Myopathies | Traitement symptomatique | Non applicable | COMPLETED | Cerebral Palsy (CP) is is estimated to be around 1.5-3 per live birth, wit… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:34 | Détail |
| IL1 Inhibition in FOP NCT06724562 · NCT06724562 | Myopathies | Traitement symptomatique | À vérifier | RECRUITING | This is an observational pre-post study to observe if the off label use of… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:34 | Détail |
| Low Level Laser Therapy NCT07753460 · Low-Level Laser Therapy in the Treatment of Trigger Finger | Myopathies | Immunomodulation · Traitement symptomatique | Non applicable | RECRUITING | Trigger finger, also known as stenosing tenosynovitis, is one of the most… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:34 | Détail |
| ME/CFS — Controlled Trial of Hydrogen Water as a Treatment for Myalgi… NCT07753122 · NCT07753122 | Myopathies | Traitement symptomatique | Non applicable | RECRUITING | This is a 16-week controlled treatment trial of an over-the -counter suppl… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:34 | Détail |
| Micro-Fragmented Adipose Tissue (MFAT) injection NCT07748793 · MFAT — Autologous Fat Grafting for the Treatment of Chronic Tendinopathy | Myopathies | Traitement symptomatique · Thérapie génique | Non applicable | NOT_YET_RECRUITING | The goal of this clinical trial is to learn whether a one-time injection o… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:34 | Détail |
| Patient-Centered Assessment of Symptoms and Outcomes NCT03952624 · NCT03952624 | Myopathies | Traitement symptomatique | À vérifier | ACTIVE_NOT_RECRUITING | Background: The cause of fatigue is not well understood. It can be felt di… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:34 | Détail |
| RCT — The Effect of Multimodal Approach of Electrotherapy Versus Shoc… NCT07750080 · NCT07750080 | Myopathies | Traitement symptomatique | Non applicable | RECRUITING | Tennis Elbow (or Lateral Epicondylalgia) is one of the most common overloa… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:34 | Détail |
| Study of Intramuscular Injections of OnabotulinumtoxinA to Assess Cha… NCT06150729 · NCT06150729 | Myopathies | Traitement symptomatique | À vérifier | COMPLETED | Spasticity is often observed as muscle tightness and stiffness in the uppe… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:34 | Détail |
| TMD — The Effects of Pilates Exercises on Women With Myogenic Temporo… NCT07750145 · NCT07750145 | Myopathies | Ralentissement de la progression · Traitement symptomatique | Non applicable | COMPLETED | The aim of this study is to investigate the effects of an 8-week Pilates e… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:34 | Détail |
| TSK-TMD-ITA — The Italian Version of the Tampa Scale for Kinesiophobi… NCT07750509 · NCT07750509 | Myopathies | Ralentissement de la progression · Traitement symptomatique · Thérapie génique | À vérifier | NOT_YET_RECRUITING | This observational, cross-sectional study aims to translate, culturally ad… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:34 | Détail |
| Ultrasound-guided dry needling NCT07550322 · Dry Needling vs ESWT in Lateral Epicondylitis | Myopathies | Traitement symptomatique | Non applicable | ACTIVE_NOT_RECRUITING | This randomized single-blind controlled trial aims to compare the effectiv… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:34 | Détail |
| Using Personalized Rehabilitation to Reduce Disease and Increase Acti… NCT07749547 · NCT07749547 | Myopathies | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | Polymyalgia rheumatica (PMR) is a condition that causes joint pain and sti… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:34 | Détail |
| Vagus nerve stimulation NCT06237595 · Vagus Nerve Stimulation in Fibromyalgia | Myopathies | À vérifier | Non applicable | COMPLETED | Vagus nerve stimulation is thought to reduce sympathetic nerve outflow and… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:34 | Détail |
| AOC-1020 NCT07038200 · FORTITUDE-3 — A Study to Evaluate Del-brax (Also Referred to as AOC 1020) in Par… | Myopathies | À vérifier | Phase 3 | RECRUITING | A Randomized, Double-blind, Placebo-controlled, Phase 3 Study to Evaluate… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:36 | Détail |
| AOC 1044 NCT06244082 · EXPLORE44OLE — Ph2 Open-label Study of AOC 1044 in Duchenne Muscular Dystrophy P… | Myopathies | À vérifier | Phase 2 | ACTIVE_NOT_RECRUITING | A Randomized, Double-blind, Placebo-controlled, Phase 3 Study to Evaluate… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:36 | Détail |
| BBP-418 NCT04800874 · Study of BBP-418 in Patients With LGMD2I | Myopathies | À vérifier | Phase 2 | ACTIVE_NOT_RECRUITING | BBP-418 is being developed for the treatment of patients with Limb-Girdle… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:36 | Détail |
| BMN 351 NCT07573631 · An Open-Label Extension Study to Evaluate the Long-term Safety and Efficacy of B… | Myopathies | À vérifier | Phase 2 | ENROLLING_BY_INVITATION | This open-label extension study aims to evaluate the long-term safety and… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:36 | Détail |
| CDLink — CureDuchenne Link®: A Resource for Research NCT04972604 · NCT04972604 | Myopathies | À vérifier | À vérifier | COMPLETED | CureDuchenne link is a data hub comprised of integrated biospecimens, clin… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:36 | Détail |
| Del-desiran (AOC 1001) NCT07008469 · HARBOR-OLE — Global Open-Label Extension Study of Del-desiran for the Treatment… | Myopathies | À vérifier | Phase 3 | ENROLLING_BY_INVITATION | A Global Phase 3 Open-Label Extension Study to Assess the Long-Term Safety… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:36 | Détail |
Découverte scientifique
Recherches et trouvailles 0
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune trouvaille ne correspond aux filtres. | |||||||
Bibliographie
Publications 588
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Potential Epigenetic Mechanisms of High-Frequency rTMS in the Treatme… Non-invasive Neuromodulation · PMID 42582898 | Myopathies | Thérapie génique | Publication | PubMed | Voir la publication source Repetitive Transcranial Magnetic Stimulation (rTMS) is an FDA-approved, non-invasive neuromodulation technique with cli… | Noro psikiyatri arsivi 2026-08-13 15:02:10 | Source |
| Efficacy and safety of risdiplam in patients with type 1 spinal muscu… SOUL-DM1 — Symptoms and Outcome Measures for Upper- Limb Function in Myotonic Dystrophy Type 1… | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source FIREFISH was a multicentre, open-label, two-part, phase 2 trial that assessed the safety, tolerability, pharmacokinetic… | The Lancet. Child & adolescent health 2026-08-13 15:02:08 | Source |
| Radiological Prevalence of Popliteal Artery Entrapment in Individuals… Utilization of High Frequency Ultrasound to Diagnose Chronic Exertional Compartment Syndrome ·… | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source Determine the radiological prevalence of popliteal artery entrapment (PAE) in subjects with anterior leg compartment ch… | Clinical journal of sport medicine : official journal… 2026-08-13 15:02:07 | Source |
| [Diseases and overuse injuries of the lower extremities in long dista… Utilization of High Frequency Ultrasound to Diagnose Chronic Exertional Compartment Syndrome ·… | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source Running is one of the most popular sports worldwide, with running events attracting hundreds of thousands of runners of… | Zeitschrift fur Rheumatologie 2026-08-13 15:02:07 | Source |
| Expression Defects of SCN5A Common Polymorphisms S524Y and H558R in t… Mexiletine · PMID 42587826 | Myopathies | Thérapie génique | Publication | PubMed | Voir la publication source The cardiac sodium channel Na1.5, encoded by SCN5A, generates the inward sodium current required for myocardial excitab… | Cells 2026-08-13 15:02:06 | Source |
| Universal Metal-Free Deborylation-Deuteration via Redox-Decoupled Tan… Mexiletine · PMID 42561327 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Flow electrochemical synthesis is a promising platform for constructing value-added targets such as d-labeled compounds… | Journal of the American Chemical Society 2026-08-13 15:02:06 | Source |
| Empowered Relief for Youth: Development, feasibility and early effect… Pain Science Education · PMID 42542155 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source Empowered Relief (ER) is a single-session pain management class that teaches pain science education and self-regulatory… | The journal of pain 2026-08-13 15:02:02 | Source |
| Beyond the first switch: multiple switching, cross-switching, and noc… GenPHSat injection (Safety) · PMID 42590845 | Myopathies | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source In health systems outside the United States (US) with longer biosimilar experience, use has shifted from a question of… | Expert opinion on biological therapy 2026-08-13 15:01:58 | Source |
| Detection of antisense oligonucleotides from biological samples by li… GenPHSat injection (Safety) · PMID 42590939 | Myopathies | Thérapie génique | Publication | PubMed | Voir la publication source This study developed a detection method for antisense oligonucleotides (ASOs) by ligase detection reaction (LDR) using… | BioTechniques 2026-08-13 15:01:58 | Source |
| Grape-Derived Exosome-like Nanoparticles Ameliorate Prediabetes in Mi… Glutamine · PMID 42589601 | Myopathies | Ralentissement de la progression | Publication | PubMed | Voir la publication source This study investigates the effects of grape-derived exosomes on prediabetic mice and elucidates their underlying mecha… | International journal of molecular sciences 2026-08-13 15:01:56 | Source |
| Species Dynamics and Gene Expression in Algal Polycultures Under Mixo… Glutamine · PMID 42590830 | Myopathies | Thérapie génique | Publication | PubMed | Voir la publication source Mixotrophic cultivation of microalgal polycultures can enhance biomass productivity and nutrient recovery from wastewat… | Biotechnology and bioengineering 2026-08-13 15:01:56 | Source |
| Creatine monohydrate supplementation for recovery from muscle disuse:… Creatine Monohydrate · PMID 42539704 | Myopathies | Immunomodulation | Publication | PubMed | Voir la publication source Creatine monohydrate supplementation is best known as an ergogenic aid. However, its potential role in recovery from mu… | Sports medicine and health science 2026-08-13 15:01:55 | Source |
| Effects of creatine supplementation with and without exercise and die… Creatine Monohydrate · PMID 42578920 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Theoretically, CrM supplementation during a weight loss and exercise intervention may help older individuals promote mo… | Journal of the International Society of Sports Nutriti… 2026-08-13 15:01:55 | Source |
| A machine learning approach to predict treatment response in myofasci… trigger point injection · PMID 42572026 | Myopathies | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Trigger point injection (TPI) therapy is widely used for masseter myofascial pain syndrome (MPS), yet outcomes vary sub… | BMC oral health 2026-08-13 15:01:51 | Source |
| Functional recovery after trigger point injection in pediatric anteri… trigger point injection · PMID 42581245 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source Anterior Cutaneous Nerve Entrapment Syndrome (ACNES) is an under-recognized cause of chronic abdominal pain in children… | European journal of pediatrics 2026-08-13 15:01:51 | Source |
| A pharmacometric framework for norepinephrine transporter occupancy a… Desipramine · PMID 42549822 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Norepinephrine transporter (NET) inhibition is a relevant mechanism across psychotropic medications, although prescribi… | Journal of psychopharmacology (Oxford, England) 2026-08-13 15:01:49 | Source |
| Stepwise Translational Validation of the Screening Hit Desipramine Re… Desipramine · PMID 42587754 | Myopathies | Thérapie cellulaire | Publication | PubMed | Voir la publication source Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal interstitial lung disease with limited treatment options… | Cells 2026-08-13 15:01:49 | Source |
| Impact of an Antimicrobial Stewardship intervention on clinical and e… Behavioral Interventions for Controlling Oral Behaviors · PMID 42575221 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Urinary tract infections (UTIs) are a common indication for Outpatient Parenteral Antimicrobial Therapy (OPAT) and ofte… | International journal of antimicrobial agents 2026-08-13 15:01:45 | Source |
| Neuroprotective effects of gallic acid against docetaxel-induced peri… Behavioral Interventions for Controlling Oral Behaviors · PMID 42573976 | Myopathies | Neuroprotection · Immunomodulation | Publication | PubMed | Voir la publication source This study focuses on the potential neuroprotective effects of gallic acid (GA) against docetaxel (DOC)-induced periphe… | Molecular and cellular biochemistry 2026-08-13 15:01:45 | Source |
| When Neurodevelopment Meets Autoimmunity: Pemphigus Foliaceus in Rett… IvIg · PMID 42589518 | Myopathies | Immunomodulation | Publication | PubMed | Voir la publication source Rett syndrome (RTT, OMIM 312750) is a complex multisystem neurodevelopmental disorder. Evidence suggests that RTT may h… | International journal of molecular sciences 2026-08-13 15:01:45 | Source |
Exploration — prudence
Pistes exploratoires 6
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| N-PPG N-PPG — modulation métabolique cérébrale | Myopathies | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation métabolique et mitohormèse N-PPG est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être pertinents pour Myopat… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |
| Vecteur Ple389 (ADORA2A) MiniPromoter Ple389 — ciblage striatal | Myopathies | Thérapie génique | Hypothèse exploratoire | Rapprochement automatique non validé | Expression génique ciblée dans les neurones striataux Vecteur Ple389 (ADORA2A) est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être per… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |
| α-Amyrin α-Amyrin — protection mitochondriale | Myopathies | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Protection mitochondriale et modulation de la pathologie Tau α-Amyrin est étudié dans Maladie d’Alzheimer et documente plusieurs axes biologiques pouvant être pertinents pour Myopa… | Rapprochement Biomedical Watch · Maladie d’Alzheimer | Détail |
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Myopathies | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation immunométabolique de la microglie 4-octyl itaconate et dérivés est étudié dans Sclérose latérale amyotrophique et documente plusieurs axes biologiques po… | Rapprochement Biomedical Watch · Sclérose latérale amy… | Détail |
| Thonningianin A Thonningianin A — neuroprotection anti-amyloïde | Myopathies | Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation du stress oxydatif et des protéines associées à Alzheimer Thonningianin A est étudié dans Maladie d’Alzheimer et documente plusieurs axes biologiques pouvant être pertinents pou… | Rapprochement Biomedical Watch · Maladie d’Alzheimer | Détail |
| Vutiglabridin Vutiglabridin — autophagie et PON2 | Myopathies | Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Activation de PON2 et stimulation de l’autophagie Vutiglabridin est étudié dans Maladie d’Alzheimer et documente plusieurs axes biologiques pouvant être pertinents pour… | Rapprochement Biomedical Watch · Maladie d’Alzheimer | Détail |