Universiteit Antwerpen — Biomedical Watch V2

Traitements5programmes

Essais2liés

Publications5liées

SourceDBlocale

Traitements

5

Molécule	Indication / population	Phase	Objectif	Pays	Résultat
Colli-Pee 20 mL device with UCMThe goal of the MYSSELF (Methylation Profiling in Self-Samples for Identification of (Epi)Genetic Biomarkers for Gynecological Cancers) study is to investigate which biological markers (i.e., (epi)genetic biomarkers) found in self-collected samples, such as first-void urine and vaginal samples, are linked to the presence of endometrial, ovarian, vulvar, or vaginal (pre-)cancer or to postmenopausal bleeding. Samples collected by clinicians from the cervix or vulva, as well as blood and tissue samples, will be used for comparison. The study will explore whether these markers could help improve earlier and less invasive detection of gynecological cancers in the future.	Cancer	Non applicable	À vérifier	Belgium	À vérifier
Evalyn BrushThe goal of the MYSSELF (Methylation Profiling in Self-Samples for Identification of (Epi)Genetic Biomarkers for Gynecological Cancers) study is to investigate which biological markers (i.e., (epi)genetic biomarkers) found in self-collected samples, such as first-void urine and vaginal samples, are linked to the presence of endometrial, ovarian, vulvar, or vaginal (pre-)cancer or to postmenopausal bleeding. Samples collected by clinicians from the cervix or vulva, as well as blood and tissue samples, will be used for comparison. The study will explore whether these markers could help improve earlier and less invasive detection of gynecological cancers in the future.	Cancer	Non applicable	À vérifier	Belgium	À vérifier
ivermectinRandomized clinical trial in the Logo health zone, in Ituri province, Democratic Republic of Congo to compare seizure freedom in onchocerciasis infested epilepsy patients who ivermectin treatment once a year compared to 2 and 3 times a year. All participants also receive anti-epileptic drugs according to local guidelines for epilepsy treatment. Participants will be followed for 12 months. The primary endpoint is seizure freedom defined as no seizures during the last fourth months of the trial.	Épilepsie	Phase 4	À vérifier	Democratic Republic of the Congo	À vérifier
ivermectinRandomized clinical trial in the Logo health zone, in Ituri province, Democratic Republic of Congo to compare seizure freedom in onchocerciasis infested epilepsy patients who ivermectin treatment once a year compared to 2 and 3 times a year. All participants also receive anti-epileptic drugs according to local guidelines for epilepsy treatment. Participants will be followed for 12 months. The primary endpoint is seizure freedom defined as no seizures during the last fourth months of the trial.	Épilepsie	Phase 4	À vérifier	Democratic Republic of the Congo	À vérifier
Colli-Pee 20 mL device with UCMThe goal of the MYSSELF (Methylation Profiling in Self-Samples for Identification of (Epi)Genetic Biomarkers for Gynecological Cancers) study is to investigate which biological markers (i.e., (epi)genetic biomarkers) found in self-collected samples, such as first-void urine and vaginal samples, are linked to the presence of endometrial, ovarian, vulvar, or vaginal (pre-)cancer or to postmenopausal bleeding. Samples collected by clinicians from the cervix or vulva, as well as blood and tissue samples, will be used for comparison. The study will explore whether these markers could help improve earlier and less invasive detection of gynecological cancers in the future.	Cancer	Non applicable	À vérifier	Belgium	À vérifier

Essais cliniques

2

Molécule	Indication / population	Phase	NCT	Titre	Statut
Colli-Pee 20 mL device with UCM	Cancer	Non applicable	NCT07902375	MYSSELF — Methylation Profiling in Self-Samples for Identification of (Epi)Genetic Biomarkers for Gynecological Cancers	RECRUITING
ivermectin	Épilepsie	Phase 4	NCT03852303	OAETREATe — Ivermectin Treatment of Persons With Onchocerciasis-associated Epilepsy	COMPLETED

Publications

5

Molécule	Indication / population	Titre	Journal	Date
ivermectin		Antiparasitic agents in oncology: Innovative mechanisms, emerging evidence and clinical potential in cancer treatment.	European journal of medicinal chemistry
ivermectin		Treatment of redness in rosacea with potassium-titanyl-phosphate (KTP) 532 nm laser with and without topical 1% ivermectin cream: a randomized split-face trial.	The Journal of dermatological treatment
ivermectin		Simple and efficient HPLC-MS/MS method for simultaneous extraction and quantification of anthelmintics in equine manure.	MethodsX
ivermectin		ALSUntangled #84 - ivermectin.	Amyotrophic lateral sclerosis & frontotemporal degeneration
ivermectin		In Vivo Acaricidal Effect of Linoleic Acid and Olive Oil Against Psoroptes cuniculi Mites in Experimentally Infested Rabbits.	Acta parasitologica