Universidade Metodista de Piracicaba — Biomedical Watch V2

Traitements3programmes

Essais1liés

Publications0liées

SourceDBlocale

Traitements

3

Molécule	Indication / population	Phase	Objectif	Pays	Résultat
Active Transcranial Direct Current Stimulation (tDCS)Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by motor and non-motor impairments that negatively affect functional independence and quality of life. Although multimodal rehabilitation approaches have demonstrated therapeutic benefits, underlying pathophysiological mechanisms may limit the magnitude and persistence of treatment effects. In this context, transcranial direct current stimulation (tDCS) has emerged as a potential strategy to enhance neuroplasticity and optimize motor responses to physical rehabilitation. This randomized, double-blind, sham-controlled clinical trial aimed to investigate the effects of tDCS combined with Nordic walking as part of a multimodal rehabilitation program on upper limb function in individuals with Parkinson's disease. Participants were randomly assigned to receive either active or sham tDCS, both combined with the same multimodal rehabilitation program over four consecutive weeks. Upper limb motor performance, manual dexterity, handgrip strength, and quality of life were assessed before and after the intervention, as well as at a 30-day follow-up. Data were analyzed using linear mixed-effects models, with a significance level of 5%.	Parkinson	Non applicable	À vérifier	Brazil	À vérifier
Sham Transcranial Direct Current Stimulation (tDCS)Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by motor and non-motor impairments that negatively affect functional independence and quality of life. Although multimodal rehabilitation approaches have demonstrated therapeutic benefits, underlying pathophysiological mechanisms may limit the magnitude and persistence of treatment effects. In this context, transcranial direct current stimulation (tDCS) has emerged as a potential strategy to enhance neuroplasticity and optimize motor responses to physical rehabilitation. This randomized, double-blind, sham-controlled clinical trial aimed to investigate the effects of tDCS combined with Nordic walking as part of a multimodal rehabilitation program on upper limb function in individuals with Parkinson's disease. Participants were randomly assigned to receive either active or sham tDCS, both combined with the same multimodal rehabilitation program over four consecutive weeks. Upper limb motor performance, manual dexterity, handgrip strength, and quality of life were assessed before and after the intervention, as well as at a 30-day follow-up. Data were analyzed using linear mixed-effects models, with a significance level of 5%.	Parkinson	Non applicable	À vérifier	Brazil	À vérifier
Active Transcranial Direct Current Stimulation (tDCS)Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by motor and non-motor impairments that negatively affect functional independence and quality of life. Although multimodal rehabilitation approaches have demonstrated therapeutic benefits, underlying pathophysiological mechanisms may limit the magnitude and persistence of treatment effects. In this context, transcranial direct current stimulation (tDCS) has emerged as a potential strategy to enhance neuroplasticity and optimize motor responses to physical rehabilitation. This randomized, double-blind, sham-controlled clinical trial aimed to investigate the effects of tDCS combined with Nordic walking as part of a multimodal rehabilitation program on upper limb function in individuals with Parkinson's disease. Participants were randomly assigned to receive either active or sham tDCS, both combined with the same multimodal rehabilitation program over four consecutive weeks. Upper limb motor performance, manual dexterity, handgrip strength, and quality of life were assessed before and after the intervention, as well as at a 30-day follow-up. Data were analyzed using linear mixed-effects models, with a significance level of 5%.	Parkinson	Non applicable	À vérifier	Brazil	À vérifier

Essais cliniques

1

Molécule	Indication / population	Phase	NCT	Titre	Statut
Active Transcranial Direct Current Stimulation (tDCS)	Parkinson	Non applicable	NCT07925567	Effects of Transcranial Direct Current Stimulation Combined With Nordic Walking on Upper Limb Function in Individuals With Parkinson's Disease	COMPLETED

Publications

0

Molécule	Indication / population	Titre	Journal	Date
Aucune publication.