Traitements2programmes
Essais1liés
Publications0liées
SourceDBlocale

Traitements

2
MoléculeIndication / populationPhaseObjectifPaysRésultat
isunakinraThis study will enroll patients with colorectal cancer that is locally advanced or metastatic. The tumor must be microsatellite stable (MSS), have a tumor mutational burden that is high (TMB-H) and be kras mutated. Patients must have been treated with available approved treatments already. In this study the investigators are testing a new type of immunotherapy, the potent IL-1 inhibitor isunakinra to be added to already approved immunotherapy (PD-1/PD-L1 inhibitor) in an attempt to get this treatment to work in this treatment resistant type of tumor. Cancer Phase 2 À vérifier United States À vérifier
isunakinraThis study will enroll patients with colorectal cancer that is locally advanced or metastatic. The tumor must be microsatellite stable (MSS), have a tumor mutational burden that is high (TMB-H) and be kras mutated. Patients must have been treated with available approved treatments already. In this study the investigators are testing a new type of immunotherapy, the potent IL-1 inhibitor isunakinra to be added to already approved immunotherapy (PD-1/PD-L1 inhibitor) in an attempt to get this treatment to work in this treatment resistant type of tumor. Cancer Phase 2 À vérifier United States À vérifier

Essais cliniques

1
MoléculeIndication / populationPhaseNCTTitreStatut
isunakinra Cancer Phase 2 NCT06634875 Isunakinra Alone and in Combination With Pembrolizumab in Patients With Colorectal Cancer (MSS) RECRUITING

Publications

0
MoléculeIndication / populationTitreJournalDate
Aucune publication.