Traitements3programmes
Essais2liés
Publications2liées
SourceDBlocale

Traitements

3
MoléculeIndication / populationPhaseObjectifPaysRésultat
AfimetoranThe purpose of this study is to evaluate the effectiveness, safety and tolerability of Afimetoran in participants with active Systemic Lupus Erythematosus (SLE). The extension period will provide additional long-term safety and efficacy data and enable those participants initially randomized to placebo to receive treatment with Afimetoran. Lupus Phase 2/3 À vérifier United States À vérifier
AfimetoranThe purpose of this study is to evaluate the effectiveness, safety and tolerability of Afimetoran in participants with active Systemic Lupus Erythematosus (SLE). The extension period will provide additional long-term safety and efficacy data and enable those participants initially randomized to placebo to receive treatment with Afimetoran. Lupus Phase 2 À vérifier United States, Argentina, Australia, Brazil, Chile, China, Colombia, France, Germany, India, Ireland, Japan, Mexico, Poland, Puerto Rico, Romania, Spain, Taiwan, United Kingdom À vérifier
AfimetoranThe purpose of this study is to evaluate the effectiveness, safety and tolerability of Afimetoran in participants with active Systemic Lupus Erythematosus (SLE). The extension period will provide additional long-term safety and efficacy data and enable those participants initially randomized to placebo to receive treatment with Afimetoran. Lupus Phase 2/3 À vérifier United States À vérifier

Essais cliniques

2
MoléculeIndication / populationPhaseNCTTitreStatut
Afimetoran Lupus Phase 2/3 NCT07881120 DISCOVERY — Study of Afimetoran in Adults With Cutaneous Lupus Erythematosus RECRUITING
Afimetoran Lupus Phase 2 NCT04895696 A Study Evaluating the Efficacy and Safety of Afimetoran Compared With Placebo in Participants With Active Systemic Lupus Erythematosus (SLE) ACTIVE_NOT_RECRUITING

Publications

2
MoléculeIndication / populationTitreJournalDate
Afimetoran Structural and immunological impacts of TOLLIP nsSNPs: A computational biology approach to drug discovery and immune system modulation. PloS one
Afimetoran Development of Kilogram-Scale Electrochemical Ni-Catalyzed Cross Electrophile Coupling in Flow. Organic process research & development