Traitements5programmes
Essais3liés
Publications0liées
SourceDBlocale

Traitements

5
MoléculeIndication / populationPhaseObjectifPaysRésultat
SonrotoclaxThe purpose of this study is to investigate the efficacy and safety of fixed-duration sonrotoclax (also known as BGB-11417) plus zanubrutinib (also known as BGB-3111) (SZ) compared with fixed-duration of venetoclax plus acalabrutinib (AV) in participants with previously untreated chronic lymphocytic leukemia (CLL). Cancer Phase 3 À vérifier United States, Australia, Brazil, Canada, China, Czechia, France, Germany, … À vérifier
TacabrutidegStudy consists of two main parts to explore tacabrutideg recommended dosing, a Phase 1 monotherapy dose finding comprised of monotherapy dose escalation and monotherapy safety expansion of selected doses, and a Phase 2 (expansion cohorts) Cancer Phase 3 À vérifier United States, Argentina, Australia, Brazil, Canada, Czechia, Germany, Italy, … À vérifier
TacabrutidegStudy consists of two main parts to explore tacabrutideg recommended dosing, a Phase 1 monotherapy dose finding comprised of monotherapy dose escalation and monotherapy safety expansion of selected doses, and a Phase 2 (expansion cohorts) Cancer Phase 1/2 À vérifier United States, Australia, Brazil, Canada, China, France, Georgia, Germany, Italy, Japan, Moldova, South Korea, Spain, Sweden, Turkey (Türkiye), United Kingdom À vérifier
SonrotoclaxThe purpose of this study is to investigate the efficacy and safety of fixed-duration sonrotoclax (also known as BGB-11417) plus zanubrutinib (also known as BGB-3111) (SZ) compared with fixed-duration of venetoclax plus acalabrutinib (AV) in participants with previously untreated chronic lymphocytic leukemia (CLL). Cancer Phase 3 À vérifier United States, Australia, Brazil, Canada, China, Czechia, France, Germany, Italy, Netherlands, New Zealand, Poland, Romania, South Korea, Spain, Sweden, United Kingdom À vérifier
TacabrutidegStudy consists of two main parts to explore tacabrutideg recommended dosing, a Phase 1 monotherapy dose finding comprised of monotherapy dose escalation and monotherapy safety expansion of selected doses, and a Phase 2 (expansion cohorts) Cancer Phase 3 Immunomodulation United States, Argentina, Australia, Brazil, Canada, Czechia, Germany, Italy, Japan, Netherlands, Poland, South Korea, Turkey (Türkiye), United Kingdom À vérifier

Essais cliniques

3
MoléculeIndication / populationPhaseNCTTitreStatut
Tacabrutideg Cancer Phase 3 NCT06846671 CaDAnCe-302 — A Study of Tacabrutideg (BGB-16673) Compared to Investigator's Choice in Participants With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Previously Exposed to Both Bruton Tyrosine Kinase (BTK) and B-cell Leukemia/Lymphoma 2 Protein (BCL2) Inhibitors RECRUITING
Sonrotoclax Cancer Phase 3 NCT07277231 A Study to Investigate Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Acalabrutinib in Adults With Previously Untreated Chronic Lymphocytic Leukemia RECRUITING
Tacabrutideg Cancer Phase 1/2 NCT05006716 CaDAnCe-101 — A Dose-Escalation and Expansion Study of Tacabrutideg (BGB-16673) in Participants With B-Cell Malignancies RECRUITING

Publications

0
MoléculeIndication / populationTitreJournalDate
Aucune publication.