Clinical trials

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Études cliniques 211

Étude / NCT ⇅ Molécule ⇅ Maladie ⇅ Phase ⇅ Statut ⇅ Résultat ⇅ Sponsor ⇅ Pays / centres ⇅ Période ⇅ Détail
NCT07656714
HFCWO Vest Plus Mechanical Cough Assist Versus Cough Assist Alone on Re…
High-frequency chest wall oscilla… Sclérose latérale amyotrophique Non applicable COMPLETED En attente / non publié Hospital Universitario Virgen Mac… Spain · Hospital Universitario Virgen Macarena, Sevil… 2021-04-15 → 2025-04-27 Ouvrir
NCT07660614
NeurALS — A Study of LTX-002 in Adult Participants With Amyotrophic Lat…
LTX-002 Sclérose latérale amyotrophique Phase 1/2 RECRUITING En attente / non publié Leal Therapeutics, Inc Germany, Italy, Netherlands, Sweden · AOU Citta della… 2026-04-29 → 2031-06 Ouvrir
NCT07287397
Study is to Assess the Safety and Tolerability of VTx-002 in Participan…
VTx-002 Sclérose latérale amyotrophique Phase 1/2 RECRUITING En attente / non publié Vector Y Therapeutics United States, Belgium, Netherlands, United Kingdom ·… 2025-12-19 → 2027-10-15 Ouvrir
NCT05829330
Ambulatory Versus Inpatient Initiation of Home Mechanical Ventilation
Ambulatory Versus Inpatient Initi… Sclérose latérale amyotrophique Non applicable COMPLETED En attente / non publié Anne Kathrine Staehr-Rye Denmark · Department of Anaesthesia, Pain and REspira… 2023-09-20 → 2026-05-01 Ouvrir
NCT07233148
Healing ALS Registry Observational Study (HAROS)
ALS medications and other medicat… Sclérose latérale amyotrophique À vérifier RECRUITING En attente / non publié Healing Advocates Registry and Mi… United States · Virtual, Park City, United States 2026-01-26 → 2036-03-31 Ouvrir
NCT07294144
Tofersen in Non-SOD1 ALS
Tofersen Sclérose latérale amyotrophique Phase 2 RECRUITING En attente / non publié Biogen United States · Emory University, Atlanta, United Sta… 2025-12-29 → 2028-05 Ouvrir
NCT04858555
Biostaging — Staging System in Amyotrophic Lateral Sclerosis
Biostaging — Staging System in Am… Sclérose latérale amyotrophique À vérifier ACTIVE_NOT_RECRUITING En attente / non publié University Hospital, Limoges France · Limoges university Hospital, Limoges, France… 2022-12-02 → 2027-12-02 Ouvrir
NCT05724173
BG-Speech-01 — Feasibility of the BrainGate2 Neural Interface System in…
BrainGate Neural Interface System Sclérose latérale amyotrophique Non applicable RECRUITING En attente / non publié Leigh R. Hochberg, MD, PhD. United States · Massachusetts General Hospital, Bosto… 2023-10-18 → 2027-07-31 Ouvrir
NCT05189106
Neurodegenerative Alzheimer's Disease and Amyotrophic Lateral Sclerosis…
Baricitinib Sclérose latérale amyotrophique Phase 1/2 COMPLETED En attente / non publié Massachusetts General Hospital United States · Massachusetts General Hospital - AD S… 2022-12-05 → 2025-06-20 Ouvrir
NCT02478450
Study to Investigate the Safety of the Transplantation (by Injection) o…
Q-Cells Sclérose latérale amyotrophique Phase 1/2 NOT_YET_RECRUITING En attente / non publié Q Therapeutics, Inc. Non communiqué 2026-12 → 2029-12 Ouvrir
NCT07017946
Intestinal Microbiome Transplant in ALS
MTP-101C Sclérose latérale amyotrophique Phase 1/2 RECRUITING En attente / non publié Duke University United States · Duke University Medical Center, Durha… 2026-01-27 → 2026-11-01 Ouvrir
NCT06392126
Personalized Antisense Oligonucleotide Therapy for A Single Participant…
nL-CHCHD-001 Sclérose latérale amyotrophique Phase 1/2 ACTIVE_NOT_RECRUITING En attente / non publié n-Lorem Foundation United States · Mayo Clinic, Jacksonville, United Sta… 2024-04-16 → 2027-04 Ouvrir
NCT07095686
Personalized Antisense Oligonucleotide for Participants With CHCHD10 ALS
nL-CHCHD-001 Sclérose latérale amyotrophique Phase 1/2 ENROLLING_BY_INVITATION En attente / non publié n-Lorem Foundation United States · Columbia University, Irving Medical C… 2024-10-02 → 2027-04 Ouvrir
NCT06977451
Personalized Antisense Oligonucleotide for a Single Participant With CH…
nL-CHCHD-001 Sclérose latérale amyotrophique Phase 1/2 ACTIVE_NOT_RECRUITING En attente / non publié n-Lorem Foundation United States · Columbia University, Irving Medical C… 2024-06-24 → 2027-06 Ouvrir
NCT07703462
Personalized Antisense Oligonucleotide Therapy for a Participant With T…
nL-TARDB-002 Sclérose latérale amyotrophique Phase 1/2 ENROLLING_BY_INVITATION En attente / non publié n-Lorem Foundation United States · Jefferson Health, Philadelphia, Unite… 2026-12 → 2028-12 Ouvrir
NCT07680361
TETRAJACO — Study of Home Use of the Jaco Robotic Manipulation Device b…
Use of the JACO robotic arm for a… Sclérose latérale amyotrophique Non applicable COMPLETED En attente / non publié Association APPROCHE France · Centre Bouffard Vercelli, Perpignan, France 2022-03-30 → 2023-04-21 Ouvrir
NCT06209515
DEGERWD — Sociodemographic Factors and Criminal Behaviour Preceding Neu…
DEGERWD — Sociodemographic Factor… Sclérose latérale amyotrophique À vérifier ACTIVE_NOT_RECRUITING En attente / non publié Kuopio University Hospital Finland · Kuopio University Hospital, Kuopio, Finland 2022-01-01 → 2029-12-31 Ouvrir
NCT07410806
HEALEY ALS Platform Trial - Regimen I NUZ-001
NUZ-001 Sclérose latérale amyotrophique Phase 2/3 ACTIVE_NOT_RECRUITING En attente / non publié Merit E. Cudkowicz, MD United States · Healey Center for ALS at Massachusett… 2026-02-25 → 2028-08-01 Ouvrir
NCT06719947
tDCS-ALS — HD-tDCS in Amyotrophic Lateral Sclerosis: A Multicenter Rand…
Active HD-tDCS Sclérose latérale amyotrophique Phase 2/3 RECRUITING En attente / non publié Universidade Federal do Rio Grand… Brazil, Chile · PneumoCardioVascular Lab - HUOL/UFRN,… 2025-11-28 → 2028-09-01 Ouvrir
NCT04297683
HEALEY ALS Platform Trial - Master Protocol
Zilucoplan Sclérose latérale amyotrophique Phase 2/3 ACTIVE_NOT_RECRUITING En attente / non publié UCB Biopharma SRL United States · Atrium Health, Charlotte, United Stat… 2020-06-14 → 2028-08 Ouvrir
NCT06351592
GOALS — First in Human (FIH) Study of ALN-SOD in Adult Participants Wit…
ALN-SOD Sclérose latérale amyotrophique Phase 1/2 RECRUITING En attente / non publié Regeneron Pharmaceuticals Australia, Belgium, Canada, Germany, Japan, Poland, S… 2024-08-28 → 2032-03-21 Ouvrir
NCT05470478
iBCI Optimization for Veterans With Paralysis
Mobile neural decoding platform (… Sclérose latérale amyotrophique Non applicable NOT_YET_RECRUITING En attente / non publié VA Office of Research and Develop… United States · Providence VA Medical Center, Provide… 2026-10-02 → 2027-06-30 Ouvrir
NCT04745299
ALSummit — Evaluation the Efficacy and Safety of Mutiple Lenzumestrocel…
Lenzumestrocel Sclérose latérale amyotrophique Phase 3 COMPLETED En attente / non publié Corestemchemon, Inc. South Korea · Hanyang university hospital, Seoul, Sou… 2021-02-24 → 2024-11-13 Ouvrir
NCT00140218
R(+) Pramipexole in Early Amyotrophic Lateral Sclerosis
R(+) pramipexole dihydrochloride … Sclérose latérale amyotrophique Phase 1/2 COMPLETED En attente / non publié Bennett, James P., Jr., M.D., Ph.… United States · David Lacomis MD, Pittsburgh, United … 2005-08 → 2006-12 Ouvrir
NCT03293069
FAIR-ALS II — Conservative Iron Chelation as a Disease-modifying Strate…
deferiprone Sclérose latérale amyotrophique Phase 2/3 COMPLETED En attente / non publié University Hospital, Lille France · Aphm Hopital La Timone, Marseille, France | … 2019-01-30 → 2024-05-06 Ouvrir