Clinical trials

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Études cliniques 211

Étude / NCT ⇅ Molécule ⇅ Maladie ⇅ Phase ⇅ Statut ⇅ Résultat ⇅ Sponsor ⇅ Pays / centres ⇅ Période ⇅ Détail
NCT07105371
Patients With ALS and Other Motor Disorders Will be Treated With Mesenc…
Exosome Secretome Sclérose latérale amyotrophique Phase 1 COMPLETED En attente / non publié The Foundation for Orthopaedics a… Antigua and Barbuda · Medical Surgical Associates Cen… 2024-07-14 → 2026-05-14 Ouvrir
NCT06126315
ALCALS — Trial on the Biological and Clinical Effects of Acetyl-L-carni…
Acetyl-l-carnitine Sclérose latérale amyotrophique Phase 2/3 RECRUITING En attente / non publié Mario Negri Institute for Pharmac… Australia, Italy · A.S.P. Palermo, Villa delle Ginest… 2025-03-26 → 2027-09 Ouvrir
NCT07862959
Early Access Program for Ulefnersen in Children, Adolescents and Adults…
Ulefnersen Sclérose latérale amyotrophique À vérifier AVAILABLE En attente / non publié Otsuka Pharmaceutical Development… Non communiqué Non communiqué Ouvrir
NCT06249867
A Study to Assess the Safety, Tolerability, and Pharmacology of Darifen…
Darifenacin 7.5 MG Extended Relea… Sclérose latérale amyotrophique Phase 2 RECRUITING En attente / non publié Oliver Blanchard Canada · Montreal Neurological Institute, Montreal, C… 2024-11-08 → 2027-11 Ouvrir
NCT07865260
PhiCube-Adults — PhiCube for Bilateral Upper Limb Neuromotor and Cognit…
PhiCube Sclérose latérale amyotrophique Non applicable NOT_YET_RECRUITING En attente / non publié Istituto di Sistemi e Tecnologie … Italy · Istituti Clinici Scientifici Maugeri IRCCS, B… 2026-09 → 2027-09 Ouvrir
NCT05163886
Study of Safety, Tolerability, and Biological Activity of LAM-002A in C…
LAM-002A Sclérose latérale amyotrophique Phase 2 COMPLETED En attente / non publié IRulya Therapeutics Inc. United States · Johns Hopkins University School of Me… 2021-12-23 → 2025-05-31 Ouvrir
NCT07521930
Interfacing With NeuroTechnology to Expand Neural Throughput (INTENT)
INTENT Neural Interface System Sclérose latérale amyotrophique Non applicable RECRUITING En attente / non publié Johns Hopkins University United States · Johns Hopkins Medicine, Baltimore, Un… 2027-01 → 2028-12 Ouvrir
NCT04220190
RAPA-501 Therapy for ALS
RAPA-501 Autologous T stem cells Sclérose latérale amyotrophique Phase 2/3 RECRUITING En attente / non publié Rapa Therapeutics LLC United States · Massachusetts General Hospital, Bosto… 2025-01-02 → 2028-07-01 Ouvrir
NCT05039099
A Study to Evaluate, Safety, Tolerability, and PK of AP-101 in Particip…
AP-101 Sclérose latérale amyotrophique Phase 2 COMPLETED En attente / non publié AL-S Pharma United States, Belgium, Canada, Germany, South Korea,… 2021-09-02 → 2025-08-13 Ouvrir
NCT05936619
MindEx: A Novel, Multifocal, Cognitive Brain-Machine Interface System
Mind Extender (MindEx) Sclérose latérale amyotrophique Non applicable RECRUITING En attente / non publié Nader Pouratian United States · UT Southwestern Medical Center, Dalla… 2026-02-20 → 2031-09-01 Ouvrir
NCT07855211
HORIZON — A Study to Learn About the Safety of BIIB147 and Its Effects …
BIIB147 Sclérose latérale amyotrophique Phase 1/2 NOT_YET_RECRUITING En attente / non publié Biogen Non communiqué 2026-10-22 → 2034-01-23 Ouvrir
NCT06726577
TP04HN106 in the Treatment of Patients With Amyotrophic Lateral Scleros…
TP04HN106 Sclérose latérale amyotrophique Phase 1/2 RECRUITING En attente / non publié Talengen Institute of Life Scienc… China · The First Affiliated Hospital of Soochow Univ… 2026-06-04 → 2027-04 Ouvrir
NCT07204977
Acamprosate in C9orf72 Hexanucleotide Repeat Expansion Amyotrophic Late…
Acamprosate calcium Sclérose latérale amyotrophique Phase 1 RECRUITING En attente / non publié National Institute of Neurologica… United States · National Institutes of Health Clinica… 2026-02-02 → 2028-09-30 Ouvrir
NCT02880033
LymphoEnergy — Oxidative Stress and Apoptosis of Energy Metabolism by D…
deferiprone Sclérose latérale amyotrophique Non applicable COMPLETED En attente / non publié University Hospital, Lille France · Hôpital Roger Salengro, CHRU de Lille, Lille… 2011-02 → 2020-03 Ouvrir
NCT05744310
ALS-LTMV — Effects of Long Term Ventilation Support on the Quality of L…
Long term mechanical ventilation … Sclérose latérale amyotrophique Non applicable RECRUITING En attente / non publié Haukeland University Hospital Norway · Akershus University Hospital, Lørenskog, Nor… 2023-04-21 → 2032-08-21 Ouvrir
NCT06881979
Fit4MR-ChrMND — High-Tech Rehabilitation Pathway for Chronic Adult Neur…
High-tech rehabilitative treatment Sclérose latérale amyotrophique Non applicable RECRUITING En attente / non publié Istituti Clinici Scientifici Maug… Italy · Azienda Ospedaliero-Universitaria di Modena, … 2025-04-28 → 2026-11 Ouvrir
NCT07833618
A Phase II Study of ALT001 in Patients With Amyotrophic Lateral Scleros…
ALT001 1.0 μg/kg Sclérose latérale amyotrophique Phase 2 NOT_YET_RECRUITING En attente / non publié Darwin Origin (Hubei) Biopharmace… China · Capital Medical University Affiliated Beijing… 2026-09-01 → 2028-12-31 Ouvrir
NCT07082192
A Study to Evaluate the Efficacy and Safety of Different Doses of CB03-…
Test drug CB03-154 5mg group Sclérose latérale amyotrophique Phase 2/3 RECRUITING En attente / non publié Shanghai Zhimeng Biopharma, Inc. China · Peking University Third Hospital, Beijing, Ch… 2025-10-30 → 2027-10 Ouvrir
NCT07834450
CORTEX-ALS — Efficacy and Safety of Cyclophosphamide in Amyotrophic Lat…
Cyclophosphamide Sclérose latérale amyotrophique Phase 2 NOT_YET_RECRUITING En attente / non publié Hebei Senlang Biotechnology Inc.,… Non communiqué 2026-10-01 → 2029-09-30 Ouvrir
NCT07836751
Using Gaze to Enable Head-neck Movements in Patients With Head Drop
neck exoskeleton controller Sclérose latérale amyotrophique Non applicable RECRUITING En attente / non publié University of Utah United States · Utah Wearable Robotics Laboratory, De… 2025-06-30 → 2026-12-01 Ouvrir
NCT07838389
Evaluation of Donor-Derived B Cell Infusions in Patients With Amyotroph…
B cell infusion Sclérose latérale amyotrophique Phase 1 NOT_YET_RECRUITING En attente / non publié Mark Poznansky United States · Sean M. Healey and AMG Center for ALS… 2027-09 → 2030-01 Ouvrir
NCT05407324
DAZALS — Dazucorilant in Patients With Amyotrophic Lateral Sclerosis
Dazucorilant 300 mg Sclérose latérale amyotrophique Phase 2 ACTIVE_NOT_RECRUITING En attente / non publié Corcept Therapeutics United States, Belgium, Canada, France, Germany, Irel… 2022-11-15 → 2027-11 Ouvrir
NCT06441682
ReALiSe — A Safety and Efficacy Study of ARGX-119 in Adult Patients Wit…
ARGX-119 Sclérose latérale amyotrophique Phase 2 TERMINATED En attente / non publié argenx Belgium, Canada, Denmark, France, Netherlands, Sweden… 2024-10-23 → 2026-08-12 Ouvrir
NCT05035823
COMMAND Early Feasibility Study: Implantable BCI to Control a Digital D…
Motor Neuroprosthesis (MNP) Sclérose latérale amyotrophique Non applicable ACTIVE_NOT_RECRUITING En attente / non publié Synchron Medical, Inc. United States · Mount Sinai Health System, New York, … 2022-04-27 → 2028-09 Ouvrir
NCT04396873
PET Imaging of Cyclooxygenases in Neurodegenerative Brain Disease
11C-MC1 Sclérose latérale amyotrophique Phase 1 RECRUITING En attente / non publié National Institute of Mental Heal… United States · National Institutes of Health Clinica… 2021-08-17 → 2030-10-03 Ouvrir