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Études cliniques 67

Étude / NCT ⇅ Molécule ⇅ Maladie ⇅ Phase ⇅ Statut ⇅ Résultat ⇅ Sponsor ⇅ Pays / centres ⇅ Période ⇅ Détail
NCT06711354
B-cell Depletion in Offspring to Women With MS Under Immunomodulatory T…
Anti-CD20 Monoclonal Antibody SEP À vérifier UNKNOWN En attente / non publié Region Stockholm Non communiqué 2025-06 → 2025-12 Ouvrir
NCT04971005
COAST — Ocrelizumab or Alemtuzumab Compared With Autologous Hematopoiet…
Autologous Hematopoietic Stem Cel… SEP Phase 2 TERMINATED En attente / non publié Universitätsklinikum Hamburg-Eppe… Germany · Universitätsklinikum Hamburg-Eppendorf, Ham… 2021-08-27 → 2022-02-04 Ouvrir
NCT02807285
Expanded Access Program for Ocrelizumab in Participants With Primary Pr…
Ocrelizumab SEP À vérifier NO_LONGER_AVAILABLE En attente / non publié Hoffmann-La Roche United States · Abington Neurological Associates, Wil… Non communiqué Ouvrir
NCT05123703
Operetta 2 — A Study to Evaluate Safety and Efficacy of Ocrelizumab in …
Ocrelizumab SEP Phase 3 ACTIVE_NOT_RECRUITING En attente / non publié Hoffmann-La Roche United States, Argentina, Australia, Austria, Belgium… 2022-05-19 → 2029-09-17 Ouvrir
NCT04458688
Investigating the Effect of Ocrelizumab in African Americans and Caucas…
Investigating the Effect of Ocrel… SEP À vérifier RECRUITING En attente / non publié Wayne State University United States · Wayne State University, Detroit, Unit… 2021-11-20 → 2030-12 Ouvrir
NCT05999604
WINDOCRE — Impact of Annual Versus Biannual Infusions of Ocrelizumab in…
Ocrelizumab Injection [Ocrevus] SEP Phase 3 ACTIVE_NOT_RECRUITING En attente / non publié Fondation Ophtalmologique Adolphe… France · CH Gonesse, Gonesse, France | CHI Poissy-Sai… 2023-11-09 → 2028-05 Ouvrir
NCT04767698
Addition of Belimumab to B-cell Depletion in Relapsing-remitting Multip…
Belimumab SEP Phase 2 TERMINATED En attente / non publié Johns Hopkins University United States · Johns Hopkins University, Baltimore, … 2021-10-01 → 2022-05-10 Ouvrir
NCT06159712
CoSHEDRMS — Comparative Study of High-Efficacy Disease Modifying Treatm…
CoSHEDRMS — Comparative Study of … SEP Non applicable UNKNOWN En attente / non publié University of Aarhus Denmark · Aarhus University, Aarhus, Denmark 2023-11-27 → 2025-11 Ouvrir
NCT04175834
PRECEPT — Comparing Risk and Severity of IRRs in Patients Premedicated …
cetrizine SEP Phase 3 COMPLETED En attente / non publié Providence Health & Services United States · Providence Neurological Specialties W… 2020-02-05 → 2022-05-13 Ouvrir
NCT03138525
Immune Profiling During Ocrelizumab Treatment in Multiple Sclerosis
Immune Profiling During Ocrelizum… SEP À vérifier COMPLETED En attente / non publié Brigham and Women's Hospital United States · Brigham and Women's Hospital, Boston,… 2017-06-20 → 2019-12-20 Ouvrir
NCT01247324
A Study of Ocrelizumab in Comparison With Interferon Beta-1a (Rebif) in…
Interferon beta-1a SEP Phase 3 COMPLETED En attente / non publié German University in Cairo United States, Argentina, Australia, Austria, Belgium… 2011-08-31 → 2022-12-31 Ouvrir
NCT06846281
Efficacy and Safety of Remibrutinib After Switching From Ocrelizumab in…
Remibrutinib oral treatment SEP Phase 3 RECRUITING En attente / non publié Novartis Pharmaceuticals United States, Argentina, Australia, Belgium, Brazil,… 2025-06-23 → 2031-06-25 Ouvrir
NCT04544436
MUSETTE — A Study to Evaluate the Efficacy, Safety and Pharmacokinetics…
Ocrelizumab SEP Phase 3 ACTIVE_NOT_RECRUITING En attente / non publié Hoffmann-La Roche United States, Argentina, Australia, Belgium, Brazil,… 2020-11-26 → 2028-08-31 Ouvrir
NCT05834855
Noisy Rebels — Non-inferiority Study of Rituximab Compared to Ocrelizum…
Rituximab SEP Phase 3 RECRUITING En attente / non publié M.D. Anderson Cancer Center Netherlands · Amsterdam UMC, location VUmc, Amsterdam… 2023-04 → 2027-05 Ouvrir
NCT02545868
A Study to Evaluate the Effects of Ocrelizumab on Immune Responses In P…
23-PPV SEP Phase 3 COMPLETED En attente / non publié Hoffmann-La Roche United States, Canada · Abington Neurological Associa… 2015-10-27 → 2021-09-21 Ouvrir
NCT06586177
REBELLION-MS — Understanding the 'Durable Effect' Concept of B-cell Mod…
Anti-CD20 antibody SEP À vérifier RECRUITING En attente / non publié Heinrich-Heine University, Duesse… Germany · Heinrich-Heine University, Duesseldorf, Düs… 2021-10-27 → 2028-12-31 Ouvrir
NCT05266469
Exploring the Profiles of RMS Patients on Ofatumumab or Ocrelizumab in …
Exploring the Profiles of RMS Pat… SEP À vérifier COMPLETED En attente / non publié Novartis Pharmaceuticals United Arab Emirates · Novartis Investigative Site, A… 2022-07-26 → 2024-11-11 Ouvrir
NCT07074886
PORTAMENTO — A Study to Assess Bioequivalence of Two Subcutaneous (SC) …
Ocrelizumab Test Formulation SEP Phase 2 ACTIVE_NOT_RECRUITING En attente / non publié Hoffmann-La Roche United States, Argentina, Brazil, France, Germany, It… 2025-11-13 → 2030-03-31 Ouvrir
NCT04035005
O'HAND — A Study to Evaluate the Efficacy and Safety of Ocrelizumab in …
Ocrelizumab SEP Phase 3 ACTIVE_NOT_RECRUITING En attente / non publié Hoffmann-La Roche United States, Australia, Belgium, Bulgaria, Canada, … 2019-08-12 → 2028-01-19 Ouvrir
NCT01765361
Assessment of Ocrelizumab (OCR) Treatment Effects on Functional Impairm…
Assessment of Ocrelizumab (OCR) T… SEP À vérifier COMPLETED En attente / non publié University Hospital, Basel, Switz… Switzerland · Dep. Neurology, Hospital of the Univers… 2012-09 → 2017-01 Ouvrir
NCT05269004
OLERO — A Rollover Study to Evaluate the Long-Term Safety and Efficacy …
Ocrelizumab SEP Phase 3 ACTIVE_NOT_RECRUITING En attente / non publié Hoffmann-La Roche United States, Argentina, Australia, Austria, Belarus… 2022-05-03 → 2027-12-31 Ouvrir
NCT07389590
Study of Ublituximab for Ocrelizumab Wearing-Off in Multiple Sclerosis
Ublituximab SEP Phase 4 RECRUITING En attente / non publié TG Therapeutics, Inc. United States · Johns Hopkins University, Baltimore, … 2026-02-10 → 2029-03 Ouvrir
NCT05232825
Ocarina II — A Phase III, Non-Inferiority, Randomized, Open-Label, Para…
Ocrelizumab IV SEP Phase 3 COMPLETED En attente / non publié Hoffmann-La Roche United States, Brazil, Czechia, Italy, New Zealand, P… 2022-05-03 → 2025-06-06 Ouvrir
NCT06780150
SurfSubQ — A Study to Investigate Effects of Ocrelizumab Treatment on N…
Ocrelizumab SEP À vérifier RECRUITING En attente / non publié Hoffmann-La Roche Germany, Switzerland · Allgemeines Krankenhaus Celle … 2024-09-26 → 2028-03-31 Ouvrir
NCT07667322
OCARINA 3 — A Study to Investigate the Safety, Tolerability, Pharmacoki…
Ocrelizumab Co-formulated With rH… SEP Phase 1 ACTIVE_NOT_RECRUITING En attente / non publié Hoffmann-La Roche United States, Brazil, Mexico, United Kingdom · Centr… 2024-12-17 → 2028-08-01 Ouvrir