Clinical trials

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Études cliniques 67

Étude / NCT ⇅ Molécule ⇅ Maladie ⇅ Phase ⇅ Statut ⇅ Résultat ⇅ Sponsor ⇅ Pays / centres ⇅ Période ⇅ Détail
NCT07282574
Mintaka — A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodyn…
RO7268489 SEP Phase 2 RECRUITING En attente / non publié Hoffmann-La Roche Australia, Brazil, France, Germany, Hungary, Italy, N… 2026-03-10 → 2030-05-30 Ouvrir
NCT04855617
Symptom Burden in Patients Treated With Ocrelizumab for Multiple Sclero…
Ocrelizumab SEP À vérifier COMPLETED En attente / non publié Hoffmann-La Roche United States · Elliot Lewis Center for Multiple Scle… 2020-10-26 → 2022-10-01 Ouvrir
NCT02637856
A Study of Ocrelizumab in Participants With Relapsing Remitting Multipl…
Ocrelizumab SEP Phase 3 COMPLETED En attente / non publié Hoffmann-La Roche United States, Canada · Advanced Neurology of Colorad… 2016-02-11 → 2019-05-03 Ouvrir
NCT07472413
Alternate Pre-med in Anti-Cluster of Differentiation 20 (CD20) Pilot Pr…
Cetirizine SEP Phase 3 NOT_YET_RECRUITING En attente / non publié University of Miami United States · UHealth Boca Raton, Boca Raton, Unite… 2026-11-01 → 2028-07-01 Ouvrir
NCT03562975
Upper Extremity Function in Multiple Sclerosis Patients With Advanced D…
Ocrelizumab SEP À vérifier COMPLETED En attente / non publié Hoffmann-La Roche United States · Carol and Frank Morsani Center for Ad… 2018-07-23 → 2023-01-11 Ouvrir
NCT06847724
Comparative PK, PD, Efficacy, and Safety Assessment of the Proposed Ocr…
CYB704 SEP Phase 3 ACTIVE_NOT_RECRUITING En attente / non publié Sandoz United States, Bosnia and Herzegovina, Bulgaria, Croa… 2025-06-10 → 2027-05 Ouvrir
NCT03599245
This is an Extension Study of the Roche P-trials to Investigate Safety …
Ocrelizumab SEP Phase 3 COMPLETED En attente / non publié Hoffmann-La Roche Argentina, Belgium, Brazil, Bulgaria, Canada, Croatia… 2018-07-12 → 2025-07-17 Ouvrir
NCT03477500
Randomized Autologous heMatopoietic Stem Cell Transplantation Versus Al…
Cyclophosphamide and ATG SEP Phase 3 ACTIVE_NOT_RECRUITING En attente / non publié Haukeland University Hospital Denmark, Netherlands, Norway, Sweden · Akademiska sju… 2018-03-21 → 2028-03-21 Ouvrir
NCT07827586
SONATA-MS — Non-interventional Study of Subcutaneous Ocrelizumab in Per…
Ocrelizumab SEP À vérifier NOT_YET_RECRUITING En attente / non publié Hoffmann-La Roche Non communiqué 2026-09-30 → 2029-05-31 Ouvrir
NCT04544449
FENtrepid — A Study to Evaluate the Efficacy and Safety of Fenebrutinib…
Fenebrutinib SEP Phase 3 ACTIVE_NOT_RECRUITING En attente / non publié Hoffmann-La Roche United States, Argentina, Australia, Austria, Brazil,… 2020-10-26 → 2027-07-21 Ouvrir
NCT04377555
Prospective Study to Assess Disease Activity and Biomarkers in Minority…
Ocrelizumab SEP Phase 4 COMPLETED En attente / non publié Hoffmann-La Roche United States, Kenya, Puerto Rico · Atlanta Neuroscie… 2020-07-30 → 2025-11-11 Ouvrir
NCT07779460
A Study Comparing Effectiveness of Kesimpta® (Ofatumumab) Versus Ocrevu…
A Study Comparing Effectiveness o… SEP À vérifier RECRUITING En attente / non publié Novartis Pharmaceuticals United States · Novartis, East Hanover, United States 2026-04-08 → 2026-12-31 Ouvrir
NCT04688788
DanNORMS — Non-inferiority Study of Ocrelizumab and Rituximab in Active…
Rituximab SEP Phase 3 ACTIVE_NOT_RECRUITING En attente / non publié M.D. Anderson Cancer Center Denmark · Danish Multiple Sclerosis Center, Rigshospi… 2021-04-28 → 2029-06-10 Ouvrir
NCT04075266
A Study of Ocrelizumab in Children and Adolescents With Relapsing-Remit…
Ocrelizumab SEP Phase 2 ACTIVE_NOT_RECRUITING En attente / non publié Hoffmann-La Roche United States, Italy, Poland · AOU Policlinico V. Ema… 2020-01-09 → 2032-04-26 Ouvrir
NCT07609719
OSSIA — A Study of Ocrelizumab Administered Subcutaneously in Participa…
OCR SC SEP Phase 4 RECRUITING En attente / non publié Genentech, Inc. United States, Puerto Rico · Atlanta Neuroscience Ins… 2026-09-02 → 2029-02-28 Ouvrir
NCT07483450
A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmac…
Ocrelizumab SEP Phase 4 ACTIVE_NOT_RECRUITING En attente / non publié Hoffmann-La Roche China · 1st Affiliated Hospital of Shanxi Medical Uni… 2025-07-04 → 2028-12-31 Ouvrir
NCT03972306
A Study To Investigate The Pharmacokinetics, Safety, And Tolerability O…
Ocrelizumab SEP Phase 1 COMPLETED En attente / non publié Hoffmann-La Roche United States · Cleveland Clinic Mellen Center, Cleve… 2019-08-12 → 2025-06-03 Ouvrir
NCT04261790
Effects of Ocrelizumab on B-cell Tolerance Defect in Relapsing Multiple…
Ocrelizumab SEP Phase 4 COMPLETED En attente / non publié Hoffmann-La Roche United States · Johns Hopkins University, Baltimore, … 2020-08-01 → 2024-11-01 Ouvrir
NCT07181811
ML45855 — Assessing the Effects of Ongoing Ocrelizumab (OCR) Therapy on…
ML45855 — Assessing the Effects o… SEP Non applicable NOT_YET_RECRUITING En attente / non publié Anza Memon United States · John D. Dingell VA Medical Center, De… 2025-09-30 → 2028-06-01 Ouvrir
NCT02861014
A Study of Ocrelizumab in Participants With Relapsing Remitting Multipl…
Ocrelizumab SEP Phase 3 COMPLETED En attente / non publié Hoffmann-La Roche Australia, Belgium, Czechia, Denmark, Estonia, Finlan… 2016-09-09 → 2020-12-15 Ouvrir
NCT04902690
The Possible Neuroprotective Effect of Ocrelizumab Via VEGF Protein Exp…
The Possible Neuroprotective Effe… SEP À vérifier UNKNOWN En attente / non publié IRCCS National Neurological Insti… Non communiqué 2021-05-31 → 2024-07-31 Ouvrir
NCT04863586
COVID-19 and Multiple Sclerosis Disease Modifying Therapies
COVID-19 and Multiple Sclerosis D… SEP À vérifier UNKNOWN En attente / non publié Nottingham University Hospitals N… United Kingdom · Nottingham University Hospitals NHS … 2021-04-01 → 2022-05-31 Ouvrir
NCT05208840
LEGATO — A Study To Determine The Effect Of Ocrelizumab On Leptomeninge…
Ocrelizumab SEP Phase 4 WITHDRAWN En attente / non publié Hoffmann-La Roche Russia · City Clinical Hospital #24; Multipal Scleros… 2023-09-15 → 2026-01-31 Ouvrir
NCT05285891
AMS05 — Ocrelizumab Discontinuation in Relapsing Multiple Sclerosis
Ocrelizumab SEP Phase 4 ACTIVE_NOT_RECRUITING En attente / non publié Hoffmann-La Roche United States · Icahn School of Medicine at Mount Sin… 2023-02-07 → 2032-02-25 Ouvrir
NCT07503340
Operetta III — A Study to Evaluate Pharmacokinetics, Safety, Tolerabili…
Ocrelizumab Co-formulated With rH… SEP Phase 3 NOT_YET_RECRUITING En attente / non publié Hoffmann-La Roche Non communiqué 2026-10-30 → 2031-08-01 Ouvrir