Clinical trials

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Études cliniques 242

Étude / NCT ⇅ Molécule ⇅ Maladie ⇅ Phase ⇅ Statut ⇅ Résultat ⇅ Sponsor ⇅ Pays / centres ⇅ Période ⇅ Détail
NCT05540327
The Willow LTE Study With M5049 in Participants With SCLE, DLE and/or S…
M5049 low dose Lupus Phase 2 ACTIVE_NOT_RECRUITING En attente / non publié Merck Healthcare KGaA, Darmstadt,… United States, Argentina, Australia, Brazil, Bulgaria… 2022-09-16 → 2028-08-12 Ouvrir
NCT07087912
BTNDV-ARD — Safety and Immunogenicity of the Live Attenuated Tetravalen…
Dengue 1,2,3,4 (attenuated) vacci… Lupus Phase 4 RECRUITING En attente / non publié University of Sao Paulo General H… Brazil · Hospital das Clinicas da Faculdade de Medici… 2026-03-16 → 2028-12-30 Ouvrir
NCT07716462
MIGHT-SLE — Home-Based High-Intensity Interval Training in Systemic Lup…
MIGHT-SLE — Home-Based High-Inten… Lupus Non applicable NOT_YET_RECRUITING En attente / non publié University of Alabama at Birmingh… United States · University of Alabama at Birmingham, … 2026-10-01 → 2027-12 Ouvrir
NCT06594068
PRIMULA Lac — Prospective Registry Investigating Maternal, Infant, and …
Anifrolumab Lupus Phase 4 RECRUITING En attente / non publié University of Cambridge United States · Research Site, Las Vegas, United Stat… 2026-01-16 → 2027-08-31 Ouvrir
NCT05966480
LUMUS — Phase 2 Placebo-Controlled Study to Assess the Safety and Effic…
Envudeucitinib Lupus Phase 2 ACTIVE_NOT_RECRUITING En attente / non publié Alumis Inc United States, Argentina, Bulgaria, Chile, Colombia, … 2023-06-26 → 2027-09-01 Ouvrir
NCT04221477
REGENCY — A Study to Evaluate the Efficacy and Safety of Obinutuzumab i…
Obinutuzumab Lupus Phase 3 ACTIVE_NOT_RECRUITING En attente / non publié Hoffmann-La Roche United States, Argentina, Brazil, Colombia, France, G… 2020-08-10 → 2031-03-02 Ouvrir
NCT07175285
BENCHMARK-SLE — A Study in Participants With Active Systemic Lupus Eryt…
BENCHMARK-SLE — A Study in Partic… Lupus À vérifier RECRUITING En attente / non publié Bristol-Myers Squibb United States, Argentina, Brazil, Canada, France, Ger… 2025-10-08 → 2032-10-05 Ouvrir
NCT07330245
DAHLIA — Achievement of LLDAS5 in Patients With Systemic Lupus Erythema…
Anifrolumab Lupus À vérifier RECRUITING En attente / non publié University of Cambridge Italy · AOU Ospedali Riuniti di Ancona - Presidio Tor… 2025-12-31 → 2028-09-30 Ouvrir
NCT07720310
Anti-CD19 CAR-T Cell Therapy for Patients With Refractory Systemic Lupu…
CAR T cells chimeric antigen rece… Lupus À vérifier ENROLLING_BY_INVITATION En attente / non publié N.N. Alexandrov National Cancer C… Belarus · NN Alexandrov National Cancer Centre of Bel… 2026-03-09 → 2030-06 Ouvrir
NCT07719322
Non Invasive Assessment of Subclinical Atherosclerosis and Cardiovascul…
Non Invasive Assessment of Subcli… Lupus À vérifier NOT_YET_RECRUITING En attente / non publié Assiut University Egypt · Assuit university hospitals, Asyut, Egypt 2026-07 → 2029-07 Ouvrir
NCT07719140
Childhood-onset Lupus Nephritis Initial Glucocorticoid-dose Harmonizati…
High-dose prednisone Lupus Phase 4 RECRUITING En attente / non publié Peking Union Medical College Hosp… China · Beijing Children's Hospital, Capital Medical … 2026-07 → 2029-03 Ouvrir
NCT06799520
A Phase 1 Trial to Evaluate the Safety, Tolerability, Pharmacodynamics,…
VIS171 Lupus Phase 1 ACTIVE_NOT_RECRUITING En attente / non publié Otsuka Pharmaceutical Development… Bulgaria, Moldova, Romania, Spain · Visterra Investig… 2025-03-17 → 2027-02-19 Ouvrir
NCT07430306
SUNFLOWER — A Study to Evaluate the Treatment Outcomes of Subcutaneous …
Anifrolumab Lupus Phase 3 RECRUITING En attente / non publié University of Cambridge United States, Canada, France, Germany, Italy, Mexico… 2026-04-13 → 2029-01-26 Ouvrir
NCT07721324
SLE — Effect of Melatonin Administration on Systemic Lupus Erythematosu…
Melatonin Lupus Phase 2/3 NOT_YET_RECRUITING En attente / non publié Nishtar Medical University Egypt · Department of Rheumatology Ain Shams Universi… 2026-07-21 → 2026-11-21 Ouvrir
NCT07721857
Neutrophil Extracellular Traps and Lupus Nephritis
Neutrophil Extracellular Traps an… Lupus À vérifier NOT_YET_RECRUITING En attente / non publié Assiut University Non communiqué 2026-09-01 → 2028-10-31 Ouvrir
NCT07721363
OBLUMEN — Obinutuzumab for Systemic Lupus Erythematosus Pure Membranous…
Obinutuzumab Lupus Phase 2 NOT_YET_RECRUITING En attente / non publié Hoffmann-La Roche France · Sorbonne University - Nephrology Départment … 2026-09-02 → 2029-09-02 Ouvrir
NCT06217107
Wellness & Workforce Solution for Lupus/Lupus Nephritis
Wellness & Workforce Solution for… Lupus Non applicable RECRUITING En attente / non publié Morehouse School of Medicine United States · Morehouse School of Medicine, Atlanta… 2024-09-14 → 2026-12-31 Ouvrir
NCT07089121
Descartes-08 for Children, Adolescents, and Young Adults With Autoimmun…
Descartes-08 Lupus Phase 1/2 RECRUITING En attente / non publié Cartesian Therapeutics United States · Cincinnati Children's Hospital Medica… 2026-01-14 → 2028-12 Ouvrir
NCT02472795
Clinical Study to Investigate the Biological Activity, Safety, Tolerabi…
Cenerimod Lupus Phase 1/2 COMPLETED En attente / non publié Viatris Innovation GmbH United States, Belarus, Bulgaria, Georgia, Russia, Uk… 2015-06-01 → 2017-02-28 Ouvrir
NCT06947460
CD19-BCMA CART Cell Therapy for Refractory SLE-LN, SSc, and pSS-PAH
CD19-BCMA CAR-T cells infusion Lupus Phase 1/2 RECRUITING En attente / non publié Beijing GoBroad Hospital China · 北京高博医院, Beijing, China 2025-04-18 → 2026-07-31 Ouvrir
NCT06032923
Double-blind Placebo Controlled Study to Evaluate the Effect of NAD+ Bo…
Double-blind Placebo Controlled S… Lupus Phase 1/2 RECRUITING En attente / non publié National Heart, Lung, and Blood I… United States · National Institutes of Health Clinica… 2024-03-13 → 2028-08-01 Ouvrir
NCT07564596
A Phase 1b/2a Study of Budoprutug in Systemic Lupus Erythematosus (SLE)
Budoprutug Lupus Phase 1/2 RECRUITING En attente / non publié Climb Bio, Inc. China · Baoji Central Hospital, Baoji, China | Mianya… 2026-06-30 → 2027-09 Ouvrir
NCT05835310
BLOSSOM — An Efficacy and Safety Study of Intravenous Anifrolumab to Tr…
Anifrolumab Lupus Phase 3 RECRUITING En attente / non publié University of Cambridge United States, Argentina, Brazil, Canada, China, Colo… 2024-03-14 → 2030-01-09 Ouvrir
NCT06897930
A Study to Investigate the Safety, Tolerability, and Efficacy of AZD012…
AZD0120 Lupus Phase 1/2 RECRUITING En attente / non publié Tongji Hospital United States, Australia, Canada, United Kingdom · Re… 2025-04-21 → 2029-05-01 Ouvrir
NCT05531565
AMETHYST — A 2-Part Study to Learn Whether Litifilimab (BIIB059) Inject…
Litifilimab Lupus Phase 2/3 ACTIVE_NOT_RECRUITING En attente / non publié Biogen United States, Argentina, Belgium, Brazil, Bulgaria, … 2022-09-13 → 2027-12-14 Ouvrir