Clinical trials

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Études cliniques 242

Étude / NCT ⇅ Molécule ⇅ Maladie ⇅ Phase ⇅ Statut ⇅ Résultat ⇅ Sponsor ⇅ Pays / centres ⇅ Période ⇅ Détail
NCT07053891
LUPKYNIS Drug-use Results Survey
Voclosporin (LUPKYNIS) Lupus À vérifier RECRUITING En attente / non publié Otsuka Pharmaceutical Co., Ltd. Japan · Pharmacovigilance Department, Osaka, Japan 2025-09-17 → 2032-06-30 Ouvrir
NCT07123519
A Clinical Study of YTS109 Cells for the Treatment of R/R Autoimmune Di…
YTS109 cell Lupus Phase 1 RECRUITING En attente / non publié China Immunotech (Beijing) Biotec… China · Institute of Hematology & Blood Diseases Hosp… 2025-08-13 → 2027-08-13 Ouvrir
NCT06978647
A Clinical Study of YTS109 Cell in R/R Autoimmune Diseases
YTS109 cell Lupus Phase 1 RECRUITING En attente / non publié China Immunotech (Beijing) Biotec… China · The First Medical Center of Chinese PLA Gener… 2025-05-19 → 2027-05-19 Ouvrir
NCT07104721
A Clinical Study of YTS109 Cell for R/R Autoimmune Diseases
YTS109 cell Lupus Phase 1 RECRUITING En attente / non publié China Immunotech (Beijing) Biotec… China · The First Affiliated Hospital of Anhui Medica… 2025-08-04 → 2028-12-30 Ouvrir
NCT07778446
A Study to Test CRT-402 in Refractory Autoimmune Disease
CRT-402 Lupus Phase 1/2 RECRUITING En attente / non publié Myeloid Therapeutics Australia · Linear Advanced Clinical Trial Centre, Gr… 2026-08-26 → 2029-08-01 Ouvrir
NCT06647069
A Study to Evaluate the Safety and Activity of SAR448501/DR-0201 in Pat…
SAR448501 Lupus Phase 1 RECRUITING En attente / non publié Sanofi Australia, Bosnia and Herzegovina, Georgia, New Zeala… 2025-03-27 → 2029-06-25 Ouvrir
NCT07598396
SOLUNA — A Study to Evaluate Mosunetuzumab in Participants With Systemi…
Mosunetuzumab Lupus Phase 2 RECRUITING En attente / non publié Hoffmann-La Roche Argentina, Brazil, Colombia, Italy, Mexico, South Afr… 2026-05-25 → 2028-08-31 Ouvrir
NCT06613360
A Study of CLN-978, a Subcutaneously Administered CD19-directed T Cell …
CLN-978 Lupus Phase 1 RECRUITING En attente / non publié Cullinan Therapeutics Inc. United States, Australia, Bulgaria, France, Georgia, … 2025-01-21 → 2027-12 Ouvrir
NCT07729826
C-CAR168, an Autologous Anti-CD20/BCMA Chimeric Antigen Receptor T-Cell…
C-CAR168 SEP Phase 2 NOT_YET_RECRUITING En attente / non publié Huashan Hospital Non communiqué 2026-09-30 → 2029-09-01 Ouvrir
NCT07873931
A Study of BMS-986553 in Participants With Refractory Autoimmune Diseas…
BMS-986553 Maladie rénale chronique Phase 1 NOT_YET_RECRUITING En attente / non publié Bristol-Myers Squibb United States, Belgium, France, Germany, Netherlands,… 2026-10-30 → 2033-01-31 Ouvrir
NCT06653556
A Study of LCAR-AIO in Subjects With Relapsed/Refractory Systemic Lupus…
LCAR-AIO T cells Lupus Phase 1 COMPLETED En attente / non publié Union Hospital, Tongji Medical Co… China · Wuhan Union Hospital, Wuhan, China 2025-01-08 → 2026-06-06 Ouvrir
NCT06943937
A Clinical Study of YTS109 Cell in R/R Systemic Lupus Erythematosus
YTS109 cell injection Lupus Phase 1 TERMINATED En attente / non publié China Immunotech (Beijing) Biotec… China · Beijing GoBroad Hospital, Beijing, China 2025-04-16 → 2026-04-25 Ouvrir
NCT06293365
Two-period Crossover Study to Demonstrate the Comparability of Pharmaco…
VAY736 1ml PFS Lupus Phase 2 ACTIVE_NOT_RECRUITING En attente / non publié Novartis Pharmaceuticals United States, Argentina, Canada, Czechia, Hungary, I… 2024-07-02 → 2029-01-16 Ouvrir
NCT07361094
Autologous CD19/BCMA Dual-Target CAR-T for Relapsed/Refractory Autoimmu…
Autologous CD19-BCMA Dual-Target … Lupus Phase 1 WITHDRAWN En attente / non publié Beijing Boren Hospital China · Beijing GoBroad Boren Hospital, Beijing, China 2025-11-06 → 2028-06 Ouvrir
NCT05798117
An Open-label, Study to Assess Safety, Efficacy and Cellular Kinetics o…
YTB323 Lupus Phase 1/2 COMPLETED En attente / non publié Novartis Pharmaceuticals Australia, France, Germany, Spain, Switzerland · Nova… 2023-02-28 → 2026-09-24 Ouvrir
NCT05126277
SIRIUS-LN — Safety, Efficacy and Tolerability of Ianalumab Versus Place…
ianalumab s.c. q4w Lupus Phase 3 ACTIVE_NOT_RECRUITING En attente / non publié Novartis Pharmaceuticals United States, Argentina, Brazil, Canada, Chile, Chin… 2022-07-14 → 2031-02-04 Ouvrir
NCT05268289
Study of Efficacy and Safety of LNP023 in Participants With Active Lupu…
Iptacopan (part 1) Lupus Phase 2 TERMINATED En attente / non publié Novartis Pharmaceuticals United States, Argentina, Brazil, China, Colombia, Fr… 2022-08-10 → 2026-10-01 Ouvrir
NCT05765006
CD19-CART(Relma-cel) for Moderate to Severe Active Systemic Lupus Eryth…
Relma-cel SEP Phase 1 UNKNOWN En attente / non publié Shanghai Ming Ju Biotechnology Co… China · Relma-cel Medical, Shanghai, China 2023-02-24 → 2025-12-30 Ouvrir
NCT07331467
Study of Ultra-Fast CD19 CAR-T Therapy for Refractory SLE
CD19 CAR-T cells SEP Phase 1 RECRUITING En attente / non publié Chongqing Precision Biotech Co., … China · Affiliated Drum Tower Hospital, Medical Schoo… 2026-01 → 2028-08 Ouvrir
NCT05352919
EMERALD — A Study to Learn More About the Long-Term Safety of Litifilim…
Litifilimab Lupus Phase 3 ENROLLING_BY_INVITATION En attente / non publié Biogen United States, Argentina, Belgium, Brazil, Bulgaria, … 2022-06-10 → 2032-05-03 Ouvrir
NCT06434363
Phase I/II Study of AD-PluReceptor Plus Tafasitamab-cxix and Lymphodepl…
Tafasitamab Lupus Phase 1/2 RECRUITING En attente / non publié M.D. Anderson Cancer Center United States · MD Anderson Cancer Center, Houston, U… 2024-07-31 → 2030-12-31 Ouvrir
NCT07104344
Study of CM355 in Patients With Systemic Lupus Erythematosus
CM355 Lupus Non applicable ACTIVE_NOT_RECRUITING En attente / non publié Second Xiangya Hospital of Centra… China · Second Xiangya Hospital of Central South Univ… 2025-09-25 → 2027-09-01 Ouvrir
NCT04868838
Daratumumab to Treat Active Lupus Nephritis
Daratumumab Lupus Phase 2 ACTIVE_NOT_RECRUITING En attente / non publié Mayo Clinic United States · Mayo Clinic in Rochester, Rochester, … 2021-04-20 → 2027-01 Ouvrir
NCT03747159
SynBioSe-2 — Synergetic B-cell Immunomodulation in SLE - 2nd Study.
Belimumab Injection Lupus Phase 3 COMPLETED En attente / non publié Leiden University Medical Center Netherlands · HagaZiekenhuis, The Hague, Netherlands … 2018-10-01 → 2026-06-22 Ouvrir
NCT07276958
A Study of LY4298445 in Healthy Participants and Participants With Syst…
LY4298445 Lupus Phase 1 RECRUITING En attente / non publié Eli Lilly and Company Australia, China, Japan · Anhui Provincial Hospital, … 2026-02-04 → 2028-03 Ouvrir